References

The retinal pigment epithelium in visual function

10.1152/physrev.00021.2004 · 2005 · External reference

Bergen, Arthur AB, The dynamic nature of Bruch's membrane

10.1016/j.preteyeres.2009.08.003 · 2010 · External reference

Hyaluronan and the functional organization of the interphotoreceptor matrix

1999 · External reference

Age-related macular degeneration: a review

10.1001/jama.2023.26074 · 2024 · External reference

Age-related macular degeneration revisited: From pathology and cellular stress to potential therapies

10.3389/fcell.2020.612812 · 2021 · External reference

A systems biology approach towards understanding and treating non-neovascular age-related macular degeneration

10.1038/s41467-019-11262-1 · 2019 · External reference

An update on the hemodynamic model of age-related macular degeneration

10.1016/j.ajo.2021.08.015 · 2022 · External reference

Macular neovascularization

10.1016/j.survophthal.2024.08.003 · 2025 · External reference

Neovascular age-related macular degeneration: therapeutic management and new-upcoming approaches

10.3390/ijms21218242 · 2020 · External reference

Transplantation of the RPE in AMD

10.1016/j.preteyeres.2007.02.002 · 2007 · External reference

Unresolved reference

External reference

A free retinal pigment epithelium–choroid graft in patients with exudative age-related macular degeneration: results up to 7 years

10.1016/j.ajo.2011.06.007 · 2012 · External reference

Sub-retinal Transplantation of hESC Derived RPE (MA09-hRPE) Cells in Patients with Stargardt’s Macular Dystrophy, NCT01345006

2011 · External reference

Comparison of FRPE and human embryonic stem cell–derived RPE behavior on aged human Bruch's membrane

10.1167/iovs.10-5386 · 2011 · External reference

HLA-matched allogeneic iPS cells-derived RPE transplantation for macular degeneration

10.3390/jcm9072217 · 2020 · External reference

Long-term follow-up of a phase 1/2a clinical trial of a stem cell-derived bioengineered retinal pigment epithelium implant for geographic atrophy

10.1016/j.ophtha.2023.12.028 · 2024 · External reference

Advances in retinal pigment epithelial cell transplantation for retinal degenerative diseases

10.1186/s13287-024-04007-5 · 2024 · External reference

Experimental transplantation of human retinal pigment epithelial cells on collagen substrates

10.1016/s0002-9394(14)73079-x · 1994 · External reference

Survival of allogeneic porcine retinal pigment epithelial sheets after subretinal transplantation

10.1167/iovs.03-0662 · 2004 · External reference

A novel approach for subretinal implantation of ultrathin substrates containing stem cell-derived retinal pigment epithelium monolayer

10.1159/000338749 · 2012 · External reference

The anterior lens capsule used as support material in RPE cell-transplantation

10.1034/j.1600-0420.2000.078005527.x · 2000 · External reference

Transplantation of retinal pigment epithelium and photoreceptors generated concomitantly via small molecule-mediated differentiation rescues visual function in rodent models of retinal degeneration

10.1186/s13287-021-02134-x · 2021 · External reference

Histological evidence for revascularisation of an autologous retinal pigment epithelium–choroid graft in the pig

10.1136/bjo.2006.103259 · 2007 · External reference

New insights into the development and progression of geographic atrophy after full thickness autologous choroidal graft

10.1167/iovs.18-24229 · 2018 · External reference

Engineering a blood-retinal barrier with human embryonic stem cell-derived retinal pigment epithelium: transcriptome and functional analysis

10.5966/sctm.2012-0134 · 2013 · External reference

Polarized vascular endothelial growth factor secretion by human retinal pigment epithelium and localization of vascular endothelial growth factor receptors on the inner choriocapillaris: evidence for a trophic paracrine relation

10.1016/s0002-9440(10)65138-3 · 1999 · External reference

Vessel formation by choroidal endothelial cells in vitro is modulated by retinal pigment epithelial cells

10.1001/archopht.1995.01100040134039 · 1995 · External reference

The choice of biopolymer is crucial to trigger angiogenesis with vascular endothelial growth factor releasing coatings

2020 · External reference

Angiogenesis in tissue engineering: breathing life into constructed tissue substitutes

10.1089/ten.2006.12.2093 · 2006 · External reference

Polymeric system for dual growth factor delivery

10.1038/nbt1101-1029 · 2001 · External reference

Angiogenic growth factor synergism in a murine tissue engineering model of angiogenesis and adipogenesis

10.2353/ajpath.2007.070066 · 2007 · External reference

Molecular mechanisms and clinical applications of angiogenesis

10.1038/nature10144 · 2011 · External reference

In vitro and in vivo biocompatibility of dextran dialdehyde cross-linked gelatin hydrogel films

10.1016/s0142-9612(98)00049-0 · 1998 · External reference

The pro-angiogenic characteristics of a cross-linked gelatin matrix

10.1016/j.biomaterials.2007.08.040 · 2007 · External reference

Bioinspired tissue engineering: the great promise of protein delivery technologies

10.1016/j.ijpharm.2008.04.030 · 2008 · External reference

Stiff gelatin hydrogels can be photo-chemically synthesized from low viscous gelatin solutions using molecularly functionalized gelatin with a high degree of methacrylation

10.1007/s10856-012-4731-2 · 2012 · External reference

Low Bloom strength gelatin as a carrier for potential use in retinal sheet encapsulation and transplantation

10.1021/bm801039n · 2009 · External reference

Transplantation of photoreceptors to light-damaged retina

1989 · External reference

Adult retinal pigment epithelial transplantation in exudative age-related macular degeneration

10.1016/j.ajo.2006.12.007 · 2007 · External reference

Subretinal delivery of ultrathin rigid-elastic cell carriers using a metallic shooter instrument and biodegradable hydrogel encapsulation

10.1167/iovs.11-8260 · 2012 · External reference

Enhancement of retinal pigment epithelial culture characteristics and subretinal space tolerance of scaffolds with 200 nm fiber topography

10.1016/j.biomaterials.2013.12.069 · 2014 · External reference

Ultrathin polyimide membrane as cell carrier for subretinal transplantation of human embryonic stem cell derived retinal pigment epithelium

10.1371/journal.pone.0143669 · 2015 · External reference

A nanofibrillar surface promotes superior growth characteristics in cultured human retinal pigment epithelium

10.1159/000324045 · 2011 · External reference

Localized RPE removal with a novel instrument aided by viscoelastics in rabbits

10.1167/tvst.5.3.11 · 2016 · External reference

Selective large-area retinal pigment epithelial removal by microsecond laser in preparation for cell therapy

10.1167/tvst.10.10.17 · 2021 · External reference

A rabbit model for outer retinal atrophy caused by surgical RPE removal, Graefe's Archive for

2023 · External reference

Clinical-grade stem cell–derived retinal pigment epithelium patch rescues retinal degeneration in rodents and pigs

10.1126/scitranslmed.aat5580 · 2019 · External reference

Survival and functionality of xeno-free human embryonic stem cell–derived retinal pigment epithelial cells on polyester substrate after transplantation in rabbits

10.1111/aos.14004 · 2019 · External reference

A step by step protocol for subretinal surgery in rabbits

2016 · External reference

Human RPE stem cells grown into polarized RPE monolayers on a polyester matrix are maintained after grafting into rabbit subretinal space

10.1016/j.stemcr.2013.11.005 · 2014 · External reference

Submacular integration of hESC-RPE monolayer xenografts in a surgical non-human primate model

10.1186/s13287-021-02395-6 · 2021 · External reference

Surgical transplantation of human RPE stem cell-derived RPE monolayers into non-human primates with immunosuppression

10.1016/j.stemcr.2020.12.007 · 2021 · External reference

Hints for gentle submacular injection in non-human primates based on intraoperative OCT guidance

10.1167/tvst.10.1.10 · 2021 · External reference

Interactions of methacryloylated gelatin and heparin modulate physico-chemical properties of hydrogels and release of vascular endothelial growth factor

10.1088/1748-605x/aacdb2 · 2018 · External reference

Controlled release of vascular endothelial growth factor from heparin-functionalized gelatin type A and albumin hydrogels

10.3390/gels3040035 · 2017 · External reference

Advanced gelatin-based vascularization bioinks for extrusion-based bioprinting of vascularized bone equivalents

10.1038/s41598-020-62166-w · 2020 · External reference

A cell culture medium that supports the differentiation of human retinal pigment epithelium into functionally polarized monolayers

2001 · External reference

Current and emerging concepts in the management of neovascular age-related macular degeneration

10.2174/187152507780363197 · 2007 · External reference

Retinal Pigment Epithelium Transplantation in Retinal Disease: Clinical Trial Development, Challenges, and Future Directions

10.3390/biom15081167 · 2025 · External reference

Vascular endothelial growth factor (VEGF) delivery approaches in regenerative medicine

10.1016/j.biopha.2023.115301 · 2023 · External reference

Advances of natural hydrogel-based vascularization strategies for soft tissue repair

10.3389/fmats.2024.1446035 · 2024 · External reference

VEGF-delivering PEG hydrogels promote vascularization in the porcine subcutaneous space

10.1002/jbm.a.37666 · 2024 · External reference

Exploring the pathogenesis of age-related macular degeneration: A review of the interplay between retinal pigment epithelium dysfunction and the innate immune system

10.3389/fnins.2022.1009599 · 2022 · External reference

Advancements in hydrogel technology for ocular drug delivery

10.37349/ebmx.2024.00023 · 2024 · External reference

Hydrogel-based therapy for age-related macular degeneration: Current innovations, impediments, and future perspectives

10.3390/gels10030158 · 2024 · External reference

Neural differentiation of human retinal pigment epithelial cells on alginate/gelatin substrate

2022 · External reference

Structure and barrier properties of human embryonic stem cell–derived retinal pigment epithelial cells are affected by extracellular matrix protein coating

10.1089/ten.tea.2013.0049 · 2014 · External reference

iPSC-RPE patch restores photoreceptors and regenerates choriocapillaris in a pig retinal degeneration model

10.1172/jci.insight.179246 · 2025 · External reference