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References from Rational design and molecular docking-guided screening of high-affinity β-glucosidase affibodies for application in a lateral flow immunoassay platform. Local targets link to admitted publications; unresolved targets remain external evidence.
Global, regional, and national burdens of colorectal cancer and inflammatory bowel disease, 1990–2021 and projections to 2050: a cross-sectional study
10.1097/js9.0000000000004428 · 2026 · External reference
The global burden of inflammatory bowel disease: from 2025 to 2045
10.1038/s41575-025-01097-1 · 2025 · External reference
Colorectal cancer in inflammatory bowel diseases: epidemiology and prevention: a review
10.3390/cancers14174254 · 2022 · External reference
Ulcerative colitis: clinical biomarkers, therapeutic targets, and emerging treatments
10.1016/j.tips.2024.08.003 · 2024 · External reference
The current consensus on ulcerative colitis, and the evidence and perspectives on the influence of gut microbiota on it
2026 · External reference
Colorectal cancer risk in ulcerative colitis: an updated population-based systematic review and meta-analysis
10.1016/j.eclinm.2025.103269 · 2025 · External reference
Stable incidence and risk factors of colorectal cancer in ulcerative colitis: a population-based cohort between 1977–2020
10.1016/j.cgh.2023.03.022 · 2024 · External reference
Mechanisms and implications of the gut microbial modulation of intestinal metabolic processes
10.1038/s44324-025-00066-1 · 2025 · External reference
β-Glucuronidase at the microbiota—host interface: dual regulatory roles and precision modulation by natural products
10.3390/molecules31040601 · 2026 · External reference
β-Glucuronidases of opportunistic bacteria are the major contributors to xenobiotic-induced toxicity in the gut
10.1038/s41598-018-34678-z · 2018 · External reference
Fusobacterium nucleatum in health and disease
10.1002/mco2.70465 · 2025 · External reference
Gut microbial β-glucuronidases and their role in the microbiome-metabolite axis in colorectal cancer
2025 · External reference
Intestinal bacterial β-glucuronidase activity of patients with colon cancer
10.1007/bf02975166 · 2001 · External reference
Advances in non-invasive screening methods for gastrointestinal cancers: how continued innovation has revolutionized early cancer detection
10.3390/cancers17071085 · 2025 · External reference
Current and future colorectal cancer screening strategies
10.1038/s41575-022-00612-y · 2022 · External reference
Current status and emerging trends in colorectal cancer screening and diagnostics
10.3390/bios13100926 · 2023 · External reference
Advances in fecal occult blood tests: the FIT revolution
10.1007/s10620-014-3445-3 · 2015 · External reference
New faecal tests in gastroenterology
10.1258/acb.2011.011150 · 2012 · External reference
Recent progress on affibody-based supramolecular architectures: moving from monomeric constructs to multivalent assemblies
10.3390/ph18111669 · 2025 · External reference
Engineering of affibody molecules
2024 · External reference
Alternative binding proteins: affibody binding proteins developed from a small three-helix bundle scaffold
10.1111/j.1742-4658.2008.06438.x · 2008 · External reference
Affibody molecules in biotechnological and medical applications
10.1016/j.tibtech.2017.04.007 · 2017 · External reference
Integrating molecular docking and molecular dynamics simulations
2019 · External reference
Discovery of a broad-spectrum affibody ligand for COVID-19 vaccine purification
2025 · External reference
Novel affibody molecules specifically bind to SARS-CoV-2 spike protein and efficiently neutralize delta and omicron variants
10.1128/spectrum.03562-22 · 2023 · External reference
A simplified and miniaturized glucometer-based assay for the detection of β-glucosidase activity
10.1631/jzus.b1800416 · 2019 · External reference
Accurate structure prediction of biomolecular interactions with AlphaFold 3
10.1038/s41586-024-07487-w · 2024 · External reference
A comprehensive benchmarking of the AlphaFold3 for predicting biomacromolecules and their interactions
10.1093/bib/bbaf616 · 2025 · External reference
DDMut-PPI: predicting effects of mutations on protein–protein interactions using graph-based deep learning
10.1093/nar/gkae412 · 2024 · External reference
Unresolved reference
2026 · External reference
Heterogeneous parallelization and acceleration of molecular dynamics simulations in GROMACS
10.1063/5.0018516 · 2020 · External reference
Expression and purification of soluble His6-tagged TEV protease
2009 · External reference
Applications of circular dichroism (CD) for structural analysis of proteins: qualification of near-and far-UV CD for protein higher order structural analysis
10.1002/jps.22695 · 2011 · External reference
Studying molecular interactions via capillary electrophoresis and microscale thermophoresis: a review
10.1002/elps.202200275 · 2023 · External reference
Structural stability of Calmodulin-target peptide complex at different temperatures based on molecular dynamics simulation
10.1186/s13065-025-01515-0 · 2025 · External reference
Abnormal SDS-PAGE migration of cytosolic proteins can identify domains and mechanisms that control surfactant binding
10.1002/pro.2107 · 2012 · External reference
The regulation of host cellular and gut microbial metabolism in the development and prevention of colorectal cancer
10.1080/1040841x.2018.1425671 · 2018 · External reference
The struggle within: microbial influences on colorectal cancer
10.1002/ibd.21354 · 2011 · External reference
Microbiota-associated metabolites and related immunoregulation in colorectal cancer
10.3390/cancers13164054 · 2021 · External reference
The role of gut microbial β-glucuronidases in carcinogenesis and cancer treatment: a scoping review
10.1007/s00432-024-06028-2 · 2024 · External reference
Targeting gut microbiota-derived β-glucuronidase to reduce enterotoxicity: research progress on strategies and prospects for the application of food and medicine homology
10.26599/fmh.2026.9420139 · 2026 · External reference
Impact of host and environmental factors on β-glucuronidase enzymatic activity: implications for gastrointestinal serotonin
10.1152/ajpgi.00026.2020 · 2020 · External reference
Recent advances of affibody molecules in biomedical applications
10.1016/j.bmc.2024.117923 · 2024 · External reference
Advancements and applications of lateral flow assays (LFAs): a comprehensive review
10.3390/s25175414 · 2025 · External reference
New technologies and reagents in lateral flow assay (LFA) designs for enhancing accuracy and sensitivity
10.1039/d3ay00844d · 2023 · External reference
Beyond traditional lateral flow assays: enhancing performance through multianalytical strategies
10.3390/bios15020068 · 2025 · External reference
Ultrasensitive and highly specific lateral flow assays for point-of-care diagnosis
10.1021/acsnano.0c10035 · 2021 · External reference
Designs, formats and applications of lateral flow assay: a literature review
10.1016/j.jscs.2014.09.001 · 2015 · External reference
Unraveling the hook effect: a comprehensive study of high antigen concentration effects in sandwich lateral flow immunoassays
10.1021/acs.analchem.0c03740 · 2020 · External reference
Adding a twist to lateral flow immunoassays: a direct replacement of antibodies with helical affibodies, from selection to application
10.1021/jacs.4c17452 · 2025 · External reference