Research graph
References from Actin filament and microtubule-centered cytoskeletal abnormalities are associated with intracellular structural disorder and cellular softening in keratoconus stromal fibroblasts. Local targets link to admitted publications; unresolved targets remain external evidence.
Keratoconus
10.1038/s41572-024-00565-3 · 2024 · External reference
Keratoconus natural progression: a systematic review and meta-analysis of 11529 eyes
10.1016/j.ophtha.2019.02.029 · 2019 · External reference
The keratoconus enigma: a review with emphasis on pathogenesis
10.1016/j.jtos.2020.03.006 · 2020 · External reference
Clinical ocular biomechanics: where are we after 20 years of progress?
10.1080/02713683.2022.2125530 · 2023 · External reference
Global spatiotemporal biomechanics using video swin transformer: multiscale validation and clinical impact for keratoconus suspects
10.1038/s41746-026-02751-x · 2026 · External reference
Subclinical keratoconus detection and characterization using motion-tracking Brillouin microscopy
10.1016/j.ophtha.2023.10.011 · 2024 · External reference
Keratocyte mechanobiology
10.1016/j.exer.2020.108228 · 2020 · External reference
Changes in collagen orientation and distribution in keratoconus corneas
10.1167/iovs.04-1253 · 2005 · External reference
Mechanical interactions and crosstalk between corneal keratocytes and the extracellular matrix
10.1016/j.exer.2014.09.003 · 2015 · External reference
Mechanotransduction and extracellular matrix homeostasis
10.1038/nrm3896 · 2014 · External reference
Assessing sarcoma cell cytoskeleton remodeling in response to varying collagen concentration
2024 · External reference
Cell mechanics and the cytoskeleton
10.1038/nature08908 · 2010 · External reference
The role of collagen in mechanotransduction and its influence on bone metabolic activity
2025 · External reference
Biochemical and mechanical regulation of actin dynamics
10.1038/s41580-022-00508-4 · 2022 · External reference
Microtubules tune mechanosensitive cell responses
10.1038/s41563-021-01108-x · 2022 · External reference
Intermediate filaments: from cell architecture to nanomechanics
10.1038/nrm2197 · 2007 · External reference
High stretchability, strength, and toughness of living cells enabled by hyperelastic vimentin intermediate filaments
10.1073/pnas.1903890116 · 2019 · External reference
Mechanotransduction gone awry
10.1038/nrm2597 · 2009 · External reference
Global consensus on keratoconus and ectatic diseases
10.1097/ico.0000000000000408 · 2015 · External reference
Effect of graphene-based nanomaterials on corneal wound healing in vitro
10.1016/j.exer.2023.109419 · 2023 · External reference
Microtubule regulation of corneal fibroblast morphology and mechanical activity in 3-D culture
10.1016/j.exer.2007.07.008 · 2007 · External reference
Transport-of-intensity differential phase contrast imaging: defying weak object approximation and matched-illumination condition
10.1364/prj.533170 · 2024 · External reference
Disorder strength measured by quantitative phase imaging as intrinsic cancer marker in fixed tissue biopsies
10.1371/journal.pone.0194320 · 2018 · External reference
Optical measurement of cycle-dependent cell growth
10.1073/pnas.1100506108 · 2011 · External reference
Unresolved reference
2021 · External reference
Evaluation of differentially expressed genes identified in keratoconus
2009 · External reference
Cofilin phosphorylation and actin cytoskeletal dynamics regulated by rho- and Cdc42-activated LIM-kinase 2
10.1083/jcb.147.7.1519 · 1999 · External reference
Downregulation of β-actin gene and human antigen R in human keratoconus
10.1167/iovs.11-9062 · 2012 · External reference
Mechanics of single cytoskeletal filaments
10.1146/annurev-biophys-030722-120914 · 2025 · External reference
Actin, a central player in cell shape and movement
10.1126/science.1175862 · 2009 · External reference
Amphiphysin 2 orchestrates nucleus positioning and shape by linking the nuclear envelope to the actin and microtubule cytoskeleton
10.1016/j.devcel.2015.09.018 · 2015 · External reference
Drug-induced changes of cytoskeletal structure and mechanics in fibroblasts: an atomic force microscopy study
10.1016/s0006-3495(00)76614-8 · 2000 · External reference
Contribution of intermediate filaments to cell stiffness, stiffening, and growth
10.1152/ajpcell.2000.279.1.c188 · 2000 · External reference
Nuclear shape, mechanics, and mechanotransduction
10.1161/circresaha.108.173989 · 2008 · External reference
Untargeted tear proteomics in a large south-Asian cohort reveals inflammatory signaling, ECM remodeling, and altered metabolism in keratoconus
10.1167/iovs.66.2.60 · 2025 · External reference
Spatial transcriptomics and single-cell RNA-sequencing revealed dendritic cell-mediated inflammation in keratoconus
10.1016/j.jtos.2025.01.008 · 2025 · External reference
Shear modulus measurement by quantitative phase imaging and correlation with atomic force microscopy
10.1016/j.bpj.2019.07.008 · 2019 · External reference
Optical phase measurements of disorder strength link microstructure to cell stiffness
10.1016/j.bpj.2016.12.016 · 2017 · External reference
