Research graph
References from Chinese yam polysaccharide attenuates DSS-induced ulcerative colitis by modulating gut microbiota and eicosanoid metabolism. Local targets link to admitted publications; unresolved targets remain external evidence.
Ulcerative colitis
10.1016/s0140-6736(23)00966-2 · 2023 · External reference
Intestinal barrier restoration in UC: dietary protein/peptide mediate microbiota-Trp-AhR axis and food processing implications
10.1016/j.foodres.2025.116799 · 2025 · External reference
The influence of cytokines on the complex pathology of ulcerative colitis
10.1016/j.autrev.2021.103017 · 2022 · External reference
Diabetes as an independent risk factor for severe inflammatory bowel disease: evidence from an inflammation–metabolism–liver coupling framework
10.3389/fendo.2025.1707507 · 2025 · External reference
IGF2/IGF2R/Sting signaling as a therapeutic target in DSS-induced ulcerative colitis
10.1016/j.ejphar.2023.176122 · 2023 · External reference
Alleviative effects of natural plant polysaccharides against DSS-induced ulcerative colitis via inhibiting inflammation and modulating gut microbiota
10.1016/j.foodres.2023.112630 · 2023 · External reference
Oryzanol ameliorates DSS-stimulated gut barrier damage via targeting the gut microbiota accompanied by the TLR4/NF-κB/NLRP3 cascade response in vivo
10.1021/acs.jafc.2c04354 · 2022 · External reference
Comparative efficacy and safety of mesalazine-based regimens with traditional Chinese medicines in mild-to-moderate ulcerative colitis
10.3389/fphar.2025.1691460 · 2026 · External reference
Gut microbiota dysbiosis in the pathogenesis of ulcerative colitis and the therapeutic efficacy of fecal microbiota transplantation: a meta-analysis
10.1186/s12876-026-05091-y · 2026 · External reference
The latest progress of natural food polysaccharides preventing ulcerative colitis by regulating intestinal microbiota
10.1016/j.jff.2022.105201 · 2022 · External reference
FMT rescues mice from DSS-induced colitis in a STING-dependent manner
10.1080/19490976.2024.2397879 · 2024 · External reference
Comparative effectiveness and safety of fecal microbiota transplantation in ulcerative colitis: an updated systematic review and meta-analysis
10.1007/s12325-025-03431-0 · 2026 · External reference
Regenerative potential of various plant-derived exosome injections in laser-induced skin wound healing in a rabbit model
10.1111/jocd.70561 · 2025 · External reference
Plant-based exosome injections for skin wound healing: experimental study
2025 · External reference
Ultrasound-assisted extraction of polysaccharides from Ginkgo biloba: process optimization, composition and anti-inflammatory activity
2024 · External reference
Structural features and in vitro antitumor activity of a water-extracted polysaccharide from Ganoderma applanatum
10.1039/d3nj01903a · 2023 · External reference
Structural characterization and hypoglycaemic effects on type 2 diabetic mice of Spirulina platensis polysaccharides and Se-modified polysaccharides
10.1016/j.fbio.2025.105826 · 2025 · External reference
Dietary fucoidan polysaccharide improved growth performance, antimicrobial immune response and gut health of juvenile Macrobrachium rosenbergii through microbiota-gut-brain axis
10.1016/j.aquaculture.2026.743922 · 2026 · External reference
Dual-configuration arabinogalactan-II synergizes with rhamnogalacturonan-I in Lycium barbarum pectin to construct an intestinal anti-inflammatory glycan scaffold
10.1016/j.carbpol.2026.124914 · 2026 · External reference
Chinese yam (Dioscorea opposita) and its bioactive compounds: the beneficial effects on gut microbiota and gut health
2024 · External reference
Extraction, separation and efficacy of yam polysaccharide
10.1016/j.ijbiomac.2024.136167 · 2024 · External reference
Chinese yam (Dioscorea) polysaccharide ameliorates ulcerative colitis in mice via modulating disorders of intestinal microecology and metabolism
10.1016/j.ijbiomac.2025.144110 · 2025 · External reference
Remodeling the gut ecosystem and its mechanism: natural products in the treatment of ulcerative colitis via regulating gut microbiota and metabolites
10.1016/j.intimp.2026.116378 · 2026 · External reference
Fecal 16S rRNA sequencing and multi-compartment metabolomics revealed gut microbiota and metabolites interactions in APP/PS1 mice
10.1016/j.compbiomed.2022.106312 · 2022 · External reference
Physicochemical characterization and immunomodulatory activity of sulfated Chinese yam polysaccharide
10.1016/j.ijbiomac.2020.09.213 · 2020 · External reference
Study on the effect of molecular weight on the gut microbiota fermentation properties of blackberry polysaccharides in vitro
10.1021/acs.jafc.2c03091 · 2022 · External reference
10.1021/acs.jafc.3c09290
10.1021/acs.jafc.3c09290 · 2024 · External reference
Dietary flaxseed oil and its blended oil alleviate high-fat diet-induced obesity in mice by improving lipid metabolism and regulating gut microbiota
2025 · External reference
Sulfated Cyclocarya Paliurus polysaccharide sorchestrates the gut microbiome to mobilize a host-derived 12-HEPE against ulcerative colitis
2026 · External reference
Characterization of the heterogeneity in oxidative stress and transcriptional programs within the in vivo microenvironment of ulcerative colitis
10.1016/j.molimm.2025.08.017 · 2025 · External reference
Exploring the antioxidant and protective effects of Marsdenia thyrsiflora Hook.f. leaf extract against carbon tetrachloride-induced hepatic damage in rat models
10.3389/fphar.2024.1463922 · 2024 · External reference
Galangin prevents against ethanol-induced intestinal barrier dysfunction and NLRP3 inflammasome activation via NF-κB/MAPK signaling pathways in mice and Caco-2 cells
2024 · External reference
Berberine regulates intestinal microbiome and metabolism homeostasis to treat ulcerative colitis
10.1016/j.lfs.2023.122385 · 2024 · External reference
Cimicifuga foetida L. polysaccharide alleviates ulcerative colitis by inhibiting pyroptosis and regulating gut microbiota
10.3389/fphar.2026.1780518 · 2026 · External reference
A genome-wide association study identifies 41 loci associated with eicosanoid levels
10.1038/s42003-023-05159-5 · 2023 · External reference
Regulation of inflammation in cancer by dietary eicosanoids
10.1016/j.pharmthera.2023.108455 · 2023 · External reference
Reactive oxygen species-responsive polymeric chloroquine nanogel for targeted oral therapy of ulcerative colitis
10.1021/acsami.5c12328 · 2025 · External reference
Methylated tirilazad alleviates DSS-induced colitis in mice through reciprocal microbiome-metabolome
10.1016/j.biopha.2026.119468 · 2026 · External reference
Research progress on the structure, derivatives, pharmacological activity, and drug carrier capacity of Chinese yam polysaccharides: a review
10.1016/j.ijbiomac.2024.129853 · 2024 · External reference
Industrially produced Rice protein ameliorates dextran sulfate sodium-induced colitis via protecting the intestinal barrier, mitigating oxidative stress, and regulating gut microbiota
10.1021/acs.jafc.2c00585 · 2022 · External reference
Aloin a prevents ulcerative colitis in mice by enhancing the intestinal barrier function via suppressing the notch signaling pathway
10.1016/j.phymed.2022.154403 · 2022 · External reference
Human derived exosome injections (ASCE+ vs. CELLEXOSOME) enhance collagen remodeling and angiogenesis in intact skin: a comparative experimental study
10.1111/jocd.70787 · 2026 · External reference
New cellular treatment factor (NCTF) and polydeoxyribonucleotide (VAMP) injections enhance skin regeneration: experimental and histological evidence
10.1111/jocd.70733 · 2026 · External reference
Astragalus improves intestinal barrier function and immunity by acting on intestinal microbiota to treat T2DM: a research review
10.3389/fimmu.2023.1243834 · 2023 · External reference
The ethanolic extract of domesticated Amauroderma rugosum alleviated DSS-induced ulcerative colitis via repairing the intestinal barrier
10.1007/s10068-024-01565-5 · 2024 · External reference
Lipopolysaccharide-binding protein expression is increased by stress and inhibits monoamine synthesis to promote depressive symptoms
10.1016/j.immuni.2023.02.002 · 2023 · External reference
Intestinal barrier biomarkers in clinical evaluation of patients with inflammatory bowel disease
10.1097/meg.0000000000002681 · 2024 · External reference
Neohesperidin attenuates DSS-induced ulcerative colitis by inhibiting inflammation, reducing intestinal barrier damage, and modulating intestinal flora composition
10.1021/acs.jafc.4c04433 · 2024 · External reference
Integrative multi-omics reveals the anti-colitis mechanisms of Polygonatum kingianum Collett & Hemsl polysaccharides in a mouse DSS model
10.3390/nu17172895 · 2025 · External reference
Hydrogen regulates ulcerative colitis by affecting the intestinal redox environment
10.2147/jir.s445152 · 2024 · External reference
Probiotic delivery for editing of the gut microbiota to mitigate colitis and maintain hepatic homeostasis via gut–liver axis
10.1021/acsnano.5c00325 · 2025 · External reference
Berberine ameliorate inflammation and apoptosis via modulating PI3K/AKT/NFκB and MAPK pathway on dry eye
10.1016/j.phymed.2023.155081 · 2023 · External reference
Almond polysaccharides inhibit DSS-induced inflammatory response in ulcerative colitis mice through NF-κB pathway
10.1016/j.ijbiomac.2024.136206 · 2024 · External reference
Shikimic acid regulates the NF-κB/MAPK signaling pathway and gut microbiota to ameliorate DSS-induced ulcerative colitis
10.1021/acs.jafc.3c00283 · 2023 · External reference
Liposome-embedded SOD attenuated DSS-induced ulcerative colitis in mice by ameliorating oxidative stress and intestinal barrier dysfunction
10.1039/d2fo03312g · 2023 · External reference
Indigo Naturalis regulates the gut microbiota to increase SCFAs content and improve ulcerative colitis lesions
10.3389/fcimb.2026.1772977 · 2026 · External reference
Key structural characteristics enhancing digestion resistance in rice starch-sugarcane polyphenols complexes
10.1016/j.foodchem.2026.148040 · 2026 · External reference
Polysaccharides from black mulberry attenuate colitis through gut microbiota mediated TNF-α/pNF-κB/ICAM-1 signaling pathway
10.1021/acs.jafc.5c01870 · 2025 · External reference
Astragalus polysaccharides alleviate DSS-induced ulcerative colitis in mice by restoring SCFA production and regulating Th17/Treg cell homeostasis in a microbiota-dependent manner
10.1016/j.carbpol.2024.122829 · 2025 · External reference
The roles of different Bacteroides uniformis strains in alleviating DSS-induced ulcerative colitis and related functional genes
10.1039/d3fo04863b · 2024 · External reference
Bacteroides uniformis-induced perturbations in colonic microbiota and bile acid levels inhibit TH17 differentiation and ameliorate colitis developments
10.1038/s41522-023-00420-5 · 2023 · External reference
Bacteroides vulgatus attenuates experimental mice colitis through modulating gut microbiota and immune responses
10.3389/fimmu.2022.1036196 · 2022 · External reference
Sea anemone-derived bioactive peptides alleviate ulcerative colitis via remodeling the gut microbiota-metabolite-immune axis
10.1016/j.jff.2026.107206 · 2026 · External reference
Lactobacillus plantarum-derived extracellular vesicles modulate macrophage polarization and gut homeostasis for alleviating ulcerative colitis
10.1021/acs.jafc.4c01758 · 2024 · External reference
A decrease in Flavonifractor plautii and its product, phytosphingosine, predisposes individuals with phlegm-dampness constitution to metabolic disorders
10.1038/s41421-025-00789-x · 2025 · External reference
5-Aminosalicylic acid alters the gut microbiota and altered microbiota transmitted vertically to offspring have protective effects against colitis
10.1038/s41598-023-39491-x · 2023 · External reference
Asiaticoside ameliorates DSS-induced colitis in mice by inhibiting inflammatory response, protecting intestinal barrier and regulating intestinal microecology
10.1002/ptr.8129 · 2024 · External reference
Amelioration of colitis by donor microbiota modulated with tea active ingredients: a fecal microbiota transplantation study
10.1016/j.foodres.2026.118473 · 2026 · External reference
Flammulina velutipes residue polysaccharide alleviates immunosuppression and intestinal injury by modulating gut microbiota and associated metabolites
10.1021/acs.jafc.4c12105 · 2025 · External reference
Kadsua coccinea extract alleviates rheumatoid arthritis via TNF-α suppression and gut microbiota modulation
10.2147/jir.s614867 · 2026 · External reference
Structural elucidation and structure-activity relationship of Porphyra haitanensis polysaccharide for preventing ulcerative colitis: targeting the immune-microbiota-metabolism axis
10.1016/j.ijbiomac.2026.154165 · 2026 · External reference
Liquid chromatography–tandem mass spectrometry-based targeted lipidomic analysis of obesity-related colorectal cancer: potential roles of the CYP eicosanoid pathway
10.1016/j.tjnut.2025.101311 · 2026 · External reference
Omega-3 polyunsaturated fatty acids and the eicosapentaenoic acid metabolite 18-hydroxyeicosapentaenoic acid (18-HEPE) attenuate experimental necrotizing enterocolitis
10.1016/j.clnu.2025.09.015 · 2025 · External reference
Association of eicosanoids and eicosanoid-related metabolites with obesity and cardiometabolic TRAITS
10.1111/dom.71269 · 2026 · External reference
Arachidonic acid metabolism in metabolic dysfunction–associated steatotic liver disease and liver fibrosis
10.1097/hc9.0000000000000802 · 2025 · External reference