Research graph
References from Anaplasma phagocytophilum Ats-1 modulates host ER translocation-coupled N-glycosylation through SDCBP and SEC61A2. Local targets link to admitted publications; unresolved targets remain external evidence.
Anaplasma phagocytophilum effector EgeA facilitates infection by hijacking TANGO1 and SCFD1 from ER–Golgi exit sites to pathogen-occupied inclusions
2024 · External reference
Anaplasma phagocytophilum outer membrane protein a interacts with sialylated glycoproteins to promote infection of mammalian host cells
10.1128/iai.00654-12 · 2012 · External reference
Anaplasma phagocytophilum Asp14 is an invasin that interacts with mammalian host cells via its C terminus to facilitate infection
10.1128/iai.00932-12 · 2013 · External reference
Anaplasma phagocytophilum surface protein AipA mediates invasion of mammalian host cells
10.1111/cmi.12286 · 2014 · External reference
The Anaplasma phagocytophilum effector AmpA hijacks host cell SUMOylation
10.1111/cmi.12380 · 2015 · External reference
Chromatin-bound bacterial effector ankyrin a recruits histone deacetylase 1 and modifies host gene expression
10.1111/cmi.12461 · 2015 · External reference
Autophagosomes induced by a bacterial Beclin 1 binding protein facilitate obligatory intracellular infection
10.1073/pnas.1218674109 · 2012 · External reference
Anaplasma phagocytophilum Ats-1 is imported into host cell mitochondria and interferes with apoptosis induction
10.1371/journal.ppat.1000774 · 2010 · External reference
Anaplasma phagocytophilum Ats-1 enhances exosome secretion through Syntenin-1
10.1186/s12866-023-03023-4 · 2023 · External reference
Sensing of bacterial type IV secretion via the unfolded protein response
10.1128/mbio.00418-12 · 2013 · External reference
Brucella-driven host N-glycome remodeling controls infection
10.1016/j.chom.2024.03.003 · 2024 · External reference
Anaplasma phagocytophilum and Ehrlichia chaffeensis type IV secretion and Ank proteins
10.1016/j.mib.2009.12.008 · 2010 · External reference
Preliminary analysis of the mechanism by which the Anaplasma phagocytophilum effector protein Ats-1 regulates host-cell spliceosome transcription (in Chinese)
2024 · External reference
Protein SRP68 of human signal recognition particle: identification of the RNA and SRP72 binding domains
10.1110/ps.051861406 · 2006 · External reference
Mechanism of protein translocation by the Sec61 translocon complex
10.1101/cshperspect.a041250 · 2023 · External reference
Structure of the mammalian oligosaccharyl-transferase complex in the native ER protein translocon
10.1038/ncomms4072 · 2014 · External reference
Membrane protein insertion at the endoplasmic reticulum
10.1146/annurev-cellbio-092910-154125 · 2011 · External reference
Structural basis for coupling protein transport and N-glycosylation at the mammalian endoplasmic reticulum
10.1126/science.aar7899 · 2018 · External reference
Cotranslational and posttranslocational N-glycosylation of proteins in the endoplasmic reticulum
10.1016/j.semcdb.2014.11.005 · 2015 · External reference
N-linked glycosylation and homeostasis of the endoplasmic reticulum
10.1016/j.ceb.2016.03.021 · 2016 · External reference
An evolving view of the eukaryotic oligosaccharyltransferase
10.1093/glycob/cwj066 · 2006 · External reference
Biological role and aberrant overexpression of Syntenin-1 in cancer: potential role as a biomarker and therapeutic target
10.3390/biomedicines11041034 · 2023 · External reference
Mechanically operated signalling scaffolds
10.1042/bst20221194 · 2024 · External reference
Scaffold proteins: hubs for controlling the flow of cellular information
10.1126/science.1198701 · 2011 · External reference
Role of site-specific glycosylation in the I-like domain of integrin β1 in small extracellular vesicle-mediated malignant behavior and FAK activation
10.3390/ijms22041770 · 2021 · External reference
Oligosaccharyltransferase: a gatekeeper of health and tumor progression
10.3390/ijms20236074 · 2019 · External reference
MITA oligomerization upon viral infection is dependent on its N-glycosylation mediated by DDOST
10.1371/journal.ppat.1010989 · 2022 · External reference
Glucose sensing and the unfolded protein response
10.1111/febs.70113 · 2025 · External reference
Fucosylation enhances colonization of ticks by Anaplasma phagocytophilum
10.1111/j.1462-5822.2010.01464.x · 2010 · External reference
Visualization of translation and protein biogenesis at the ER membrane
10.1038/s41586-022-05638-5 · 2023 · External reference
Global analysis of translocon remodeling during protein synthesis at the ER
10.1038/s41594-025-01691-6 · 2025 · External reference
N-glycan-dependent protein maturation and quality control in the ER
10.1038/s41580-025-00855-y · 2025 · External reference
N-linked sugar-regulated protein folding and quality control in the ER
10.1016/j.semcdb.2014.12.001 · 2015 · External reference
Glycosylation: mechanisms, biological functions and clinical implications
10.1038/s41392-024-01886-1 · 2024 · External reference
Glycosylation in health and disease
10.1038/s41581-019-0129-4 · 2019 · External reference
Oligosaccharyltransferase: the central enzyme of N-linked protein glycosylation
10.1007/s10545-011-9337-1 · 2011 · External reference
Infection, inflammation and host carbohydrates: a glyco-evasion hypothesis
10.1093/glycob/cws070 · 2012 · External reference
An intracellular nanobody targeting T4SS effector inhibits Ehrlichia infection
2021 · External reference
Ehrlichia secretes Etf-1 to induce autophagy and capture nutrients for its growth through RAB5 and class III phosphatidylinositol 3-kinase
10.1080/15548627.2016.1217369 · 2016 · External reference
Orientia tsutsugamushi Ank9 is a multifunctional effector that utilizes a novel GRIP-like Golgi localization domain for Golgi-to-endoplasmic reticulum trafficking and interacts with host COPB2
10.1111/cmi.12727 · 2017 · External reference
SDCBP/Syntenin-1 stabilizes BACH1 by disassembling the SCF^FBXO22–BACH1 complex in triple-negative breast cancer
10.1038/s44318-025-00440-1 · 2025 · External reference
Role of Sec61α2 translocon in insulin biosynthesis
10.2337/db24-0115 · 2024 · External reference
Quantitative proteomics identifies the core proteome of exosomes with syntenin-1 as the highest abundant protein and a putative universal biomarker
10.1038/s41556-021-00693-y · 2021 · External reference
Endocytosis blocks the vesicular secretion of exosome marker proteins
10.1126/sciadv.adi9156 · 2024 · External reference
Role of N-glycosylation in trafficking of apical membrane proteins in epithelia
10.1152/ajprenal.90340.2008 · 2009 · External reference
Inhibition of Sec61-dependent translocation by mycolactone uncouples the integrated stress response from ER stress, driving cytotoxicity via translational activation of ATF4
10.1038/s41419-018-0427-y · 2018 · External reference
Tunicamycin induces ER stress and inhibits tumorigenesis of head and neck cancer cells by inhibiting N-glycosylation
2020 · External reference
Endoplasmic reticulum stress-induced autophagy provides cytoprotection from chemical hypoxia and oxidant injury and ameliorates renal ischemia–reperfusion injury
10.1371/journal.pone.0140025 · 2015 · External reference
Breaking in and grabbing a meal: Anaplasma phagocytophilum cellular invasion, nutrient acquisition, and promising tools for their study
10.1016/j.micinf.2013.10.010 · 2013 · External reference
