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References from From single metals to mixtures: uncovering genetic risk factors for metal exposure in disease-free individuals from the EPIC-Spain cohort. Local targets link to admitted publications; unresolved targets remain external evidence.
Genetic effects on gene expression across human tissues
10.1038/nature24277 · 2017 · External reference
Unresolved reference
2024 · External reference
Diet and cancer — the European prospective investigation into cancer and nutrition
10.1038/nrc1298 · 2004 · External reference
Sources of pre-analytical variations in yield of DNA extracted from blood samples: analysis of 50,000 DNA samples in EPIC
2012 · External reference
Cadmium exposure and osteoporosis: epidemiological evidence and mechanisms
2025 · External reference
A critical review on the interactions of microplastics with heavy metals: mechanism and their combined effect on organisms and humans
10.1016/j.scitotenv.2021.147620 · 2021 · External reference
The NHGRI-EBI GWAS catalog: standards for reusability, sustainability and diversity
10.1093/nar/gkae1070 · 2025 · External reference
Tutorial: a guide to performing polygenic risk score analyses
10.1038/s41596-020-0353-1 · 2020 · External reference
Next-generation genotype imputation service and methods
10.1038/ng.3656 · 2016 · External reference
Genome-wide association study identifies loci affecting blood copper, selenium and zinc
10.1093/hmg/ddt239 · 2013 · External reference
Using transcriptomic signatures to elucidate individual and mixture effects of inorganic arsenic and manganese in human placental trophoblast HTR-8/SVneo cells
10.1093/toxsci/kfae147 · 2025 · External reference
Cadmium induces iron deficiency anemia through the suppression of iron transport in the duodenum
10.1016/j.toxlet.2020.07.005 · 2020 · External reference
[the European prospective investigation about cancer and nutrition (EPIC)]
10.1590/s1135-57272004000200004 · 2004 · External reference
Assessing the carcinogenic potential of low-dose exposures to chemical mixtures in the environment: the challenge ahead
10.1093/carcin/bgv039 · 2015 · External reference
The role of copper and zinc in irritable bowel syndrome: a mendelian randomization study
10.1093/aje/kwab180 · 2022 · External reference
The impact of genetic variation on metabolism of heavy metals: genetic predisposition?
10.1016/j.biopha.2019.108642 · 2019 · External reference
A quantile-based g-computation approach to addressing the effects of exposure mixtures
2020 · External reference
Temporal variability of blood lead, mercury, and cadmium levels in elderly panel study (2008–2014)
10.1016/j.ijheh.2016.11.014 · 2017 · External reference
Association between mixed heavy metal exposure and arterial stiffness, with alkaline phosphatase identified as a mediator
10.1007/s12011-024-04359-2 · 2025 · External reference
Association between heavy metal exposure and heart failure incidence and mortality: insights from NHANES data (2003–2018)
10.1186/s12889-025-23177-2 · 2025 · External reference
Association of both prenatal and early childhood multiple metals exposure with neurodevelopment in infant: a prospective cohort study
10.1016/j.envres.2021.112450 · 2022 · External reference
Metals and disease: a global primary health care perspective
2011 · External reference
A state-of-the-science review on metal biomarkers
10.1007/s40572-023-00402-x · 2023 · External reference
Human blood-based exposure levels of persistent organic pollutant (POP) mixtures antagonise androgen receptor transactivation and translocation
10.1016/j.envint.2019.105083 · 2019 · External reference
Genetic disorders affecting proteins of iron and copper metabolism: clinical implications
10.2169/internalmedicine.41.762 · 2002 · External reference
A genome-wide association study provides insights into the genetic etiology of 57 essential and non-essential trace elements in humans
10.1038/s42003-024-06101-z · 2024 · External reference
Genome-wide association study of toxic metals and trace elements reveals novel associations
10.1093/hmg/ddv190 · 2015 · External reference
Metals and breast cancer risk: a prospective Study using toenail biomarkers
10.1093/aje/kwab204 · 2021 · External reference
Prediagnostic levels of copper and zinc and breast cancer risk in the ORDET cohort
10.1158/1055-9965.epi-21-1252 · 2022 · External reference
DisGeNET: a comprehensive platform integrating information on human disease-associated genes and variants
10.1093/nar/gkw943 · 2017 · External reference
Knowns and unknowns on burden of disease due to chemicals: a systematic review
2011 · External reference
European Prospective Investigation into Cancer and Nutrition (EPIC): study populations and data collection
10.1079/phn2002394 · 2002 · External reference
REVIGO summarizes and visualizes long lists of gene ontology terms
2011 · External reference
Unresolved reference
2020 · External reference
Functional mapping and annotation of genetic associations with FUMA
10.1038/s41467-017-01261-5 · 2017 · External reference
Molecular mechanisms of environmental exposures and human disease
10.1038/s41576-022-00569-3 · 2023 · External reference
Metalloestrogens exposure and risk of gestational diabetes mellitus: evidence emerging from the systematic review and meta-analysis
10.1016/j.envres.2024.118321 · 2024 · External reference
A review of toxicity and mechanisms of individual and mixtures of heavy metals in the environment
10.1007/s11356-016-6333-x · 2016 · External reference
Genetic analysis the causal associations between metal elements and thyroid cancer: a bidirectional Mendelian randomization
10.1007/s12672-025-03143-5 · 2025 · External reference
Genome-wide association and Mendelian randomization study of blood copper levels and 213 deep phenotypes in humans
10.1038/s42003-022-03351-7 · 2022 · External reference
Causal relationship between blood metal levels and breast cancer risk: a Mendelian randomization study in East Asian populations
10.1007/s12672-025-03608-7 · 2025 · External reference
Associations between individual and mixed urinary metal exposure and dyslipidemia among Chinese adults: data from the China Multi-Ethnic Cohort Study
10.1016/j.ecoenv.2024.116696 · 2024 · External reference