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References from Modulating microneedles’ array design and application force for personalizing skin permeation using design of experiments. Local targets link to admitted publications; unresolved targets remain external evidence.
A comprehensive review of microneedles: types, materials, processes, characterizations and applications
10.3390/polym13162815 · 2021 · External reference
Optimizing microneedle arrays to increase skin permeability for transdermal drug delivery
10.1111/j.1749-6632.2009.04083.x · 2009 · External reference
Mechanical characterization of dissolving microneedles: factors affecting physical strength of needles
10.3390/pharmaceutics16020200 · 2024 · External reference
Fabrication of dissolving microneedles for transdermal delivery of protein and peptide drugs: polymer materials and solvent casting micromoulding method
10.1080/10837450.2023.2285498 · 2023 · External reference
Development of a 3D printing liquid crystal display (LCD)-assisted micromolding methodology for custom fabrication of polymeric microneedles using experimental design
10.3390/pharmaceutics17121571 · 2025 · External reference
Fabrication and evaluation of transdermal microneedles for a recombinant human keratinocyte growth factor
10.4274/tjps.galenos.2020.21033 · 2021 · External reference
Transdermal drug delivery by coated microneedles: geometry effects on effective skin thickness and drug permeability
10.1016/j.cherd.2008.06.002 · 2008 · External reference
Insertion of microneedles into skin: measurement and prediction of insertion force and needle fracture force
10.1016/j.jbiomech.2003.12.010 · 2004 · External reference
Effect of microneedle design on pain in human volunteers
10.1097/ajp.0b013e31816778f9 · 2008 · External reference
The effects of geometry on skin penetration and failure of polymer microneedles
10.1080/01694243.2012.705101 · 2013 · External reference
Exploring DrugCentral: from molecular structures to clinical effects
10.1007/s10822-023-00529-x · 2023 · External reference
Transdermal delivery of drugs with microneedles—potential and challenges
10.3390/pharmaceutics7030090 · 2015 · External reference
Morphology design and precision control of microneedles by PμSL 3D printing
10.3390/polym17101351 · 2025 · External reference
Technical challenges and quality considerations for dissolving microneedles
10.1016/j.ijpharm.2026.126830 · 2026 · External reference
Microneedle-mediated delivery of donepezil: potential for improved treatment options in Alzheimer's disease
10.1016/j.ejpb.2016.03.026 · 2016 · External reference
A proposed model membrane and test method for microneedle insertion studies
10.1016/j.ijpharm.2014.05.042 · 2014 · External reference
Dissolving microneedle arrays with optimized needle geometry for transcutaneous immunization
10.1016/j.ejps.2020.105361 · 2020 · External reference
Designing multifunctional microneedles in biomedical engineering: materials, methods, and applications
10.2147/ijn.s531898 · 2025 · External reference
Polymeric microneedle drug delivery systems: mechanisms of treatment, material properties, and clinical applications—a comprehensive review
10.3390/polym16182568 · 2024 · External reference
Evaluation of geometrical effects of microneedles on skin penetration by CT scan and finite element analysis
10.1016/j.ejpb.2016.06.023 · 2016 · External reference
PVP-microneedle array for drug delivery: mechanical insight, biodegradation, and recent advances
10.1080/09205063.2022.2155778 · 2023 · External reference
Evaluation of porcine skin layers separation methods, freezing storage and anatomical site in in vitro percutaneous absorption studies using penciclovir formulations
2020 · External reference
Shape of dissolving microneedles determines skin penetration ability and efficacy of drug delivery
10.1016/j.bioadv.2022.213248 · 2023 · External reference
Dissolving microneedles in transdermal drug delivery: a critical analysis of limitations and translation challenges
10.1016/j.jconrel.2025.113794 · 2025 · External reference
Design of experiments (DoE) in pharmaceutical development
10.1080/03639045.2017.1291672 · 2017 · External reference
Microneedle patches: usability and acceptability for self-vaccination against influenza
10.1016/j.vaccine.2014.01.076 · 2014 · External reference
Impact of formulation and microneedle length on transdermal metronidazole permeation through microneedle-treated skin
10.1007/s11095-023-03640-8 · 2024 · External reference
Current status and future potential of transdermal drug delivery
10.1038/nrd1304 · 2004 · External reference
Microneedles for transdermal drug delivery
10.1016/j.addr.2003.10.023 · 2004 · External reference
Successful application of large microneedle patches by human volunteers
10.1016/j.ijpharm.2017.02.011 · 2017 · External reference
Monitoring the penetration process of single microneedles with varying tip diameters
10.1016/j.jmbbm.2014.09.015 · 2014 · External reference
Microneedle pretreatment enhances the percutaneous permeation of hydrophilic compounds with high melting points
10.1186/2050-6511-13-5 · 2012 · External reference
What is the optimal geometry of dissolving microneedle arrays? A literature review
10.3390/pharmaceutics17010124 · 2025 · External reference
Effects of plasticizing on mechanical and viscous characteristics of poly(vinyl alcohol): a comparative study between glycerol and diethanolamine
10.1002/mame.202300090 · 2023 · External reference
Pharmaceutical quality by design: product and process development, understanding, and control
10.1007/s11095-007-9511-1 · 2008 · External reference
Effects of plasticizing on mechanical and viscous characteristics of poly(vinyl alcohol): a comparative study between glycerol and diethanolamine
10.1002/mame.202300090 · ExternalCitation · doi-reference
Exploring DrugCentral: from molecular structures to clinical effects
10.1007/s10822-023-00529-x · ExternalCitation · doi-reference
Pharmaceutical quality by design: product and process development, understanding, and control
10.1007/s11095-007-9511-1 · ExternalCitation · doi-reference
Impact of formulation and microneedle length on transdermal metronidazole permeation through microneedle-treated skin
10.1007/s11095-023-03640-8 · ExternalCitation · doi-reference
Microneedles for transdermal drug delivery
10.1016/j.addr.2003.10.023 · ExternalCitation · doi-reference
Shape of dissolving microneedles determines skin penetration ability and efficacy of drug delivery
10.1016/j.bioadv.2022.213248 · ExternalCitation · doi-reference
Transdermal drug delivery by coated microneedles: geometry effects on effective skin thickness and drug permeability
10.1016/j.cherd.2008.06.002 · ExternalCitation · doi-reference
Microneedle-mediated delivery of donepezil: potential for improved treatment options in Alzheimer's disease
10.1016/j.ejpb.2016.03.026 · ExternalCitation · doi-reference
Evaluation of geometrical effects of microneedles on skin penetration by CT scan and finite element analysis
10.1016/j.ejpb.2016.06.023 · ExternalCitation · doi-reference
Dissolving microneedle arrays with optimized needle geometry for transcutaneous immunization
10.1016/j.ejps.2020.105361 · ExternalCitation · doi-reference
A proposed model membrane and test method for microneedle insertion studies
10.1016/j.ijpharm.2014.05.042 · ExternalCitation · doi-reference
Successful application of large microneedle patches by human volunteers
10.1016/j.ijpharm.2017.02.011 · ExternalCitation · doi-reference
Technical challenges and quality considerations for dissolving microneedles
10.1016/j.ijpharm.2026.126830 · ExternalCitation · doi-reference
Insertion of microneedles into skin: measurement and prediction of insertion force and needle fracture force
10.1016/j.jbiomech.2003.12.010 · ExternalCitation · doi-reference
Dissolving microneedles in transdermal drug delivery: a critical analysis of limitations and translation challenges
10.1016/j.jconrel.2025.113794 · ExternalCitation · doi-reference
Monitoring the penetration process of single microneedles with varying tip diameters
10.1016/j.jmbbm.2014.09.015 · ExternalCitation · doi-reference
Microneedle patches: usability and acceptability for self-vaccination against influenza
10.1016/j.vaccine.2014.01.076 · ExternalCitation · doi-reference
Current status and future potential of transdermal drug delivery
10.1038/nrd1304 · ExternalCitation · doi-reference
The effects of geometry on skin penetration and failure of polymer microneedles
10.1080/01694243.2012.705101 · ExternalCitation · doi-reference
Design of experiments (DoE) in pharmaceutical development
10.1080/03639045.2017.1291672 · ExternalCitation · doi-reference
PVP-microneedle array for drug delivery: mechanical insight, biodegradation, and recent advances
10.1080/09205063.2022.2155778 · ExternalCitation · doi-reference
Fabrication of dissolving microneedles for transdermal delivery of protein and peptide drugs: polymer materials and solvent casting micromoulding method
10.1080/10837450.2023.2285498 · ExternalCitation · doi-reference
Effect of microneedle design on pain in human volunteers
10.1097/ajp.0b013e31816778f9 · ExternalCitation · doi-reference
Optimizing microneedle arrays to increase skin permeability for transdermal drug delivery
10.1111/j.1749-6632.2009.04083.x · ExternalCitation · doi-reference
Microneedle pretreatment enhances the percutaneous permeation of hydrophilic compounds with high melting points
10.1186/2050-6511-13-5 · ExternalCitation · doi-reference
Designing multifunctional microneedles in biomedical engineering: materials, methods, and applications
10.2147/ijn.s531898 · ExternalCitation · doi-reference
Mechanical characterization of dissolving microneedles: factors affecting physical strength of needles
10.3390/pharmaceutics16020200 · ExternalCitation · doi-reference
What is the optimal geometry of dissolving microneedle arrays? A literature review
10.3390/pharmaceutics17010124 · ExternalCitation · doi-reference
Development of a 3D printing liquid crystal display (LCD)-assisted micromolding methodology for custom fabrication of polymeric microneedles using experimental design
10.3390/pharmaceutics17121571 · ExternalCitation · doi-reference
Transdermal delivery of drugs with microneedles—potential and challenges
10.3390/pharmaceutics7030090 · ExternalCitation · doi-reference
A comprehensive review of microneedles: types, materials, processes, characterizations and applications
10.3390/polym13162815 · ExternalCitation · doi-reference
Polymeric microneedle drug delivery systems: mechanisms of treatment, material properties, and clinical applications—a comprehensive review
10.3390/polym16182568 · ExternalCitation · doi-reference
Morphology design and precision control of microneedles by PμSL 3D printing
10.3390/polym17101351 · ExternalCitation · doi-reference
Fabrication and evaluation of transdermal microneedles for a recombinant human keratinocyte growth factor
10.4274/tjps.galenos.2020.21033 · ExternalCitation · doi-reference
