Contact and support
Need help, have a question, or want to contact the ResearchHub team?
© 2026 ResearchHub. Built for responsible scholarly connection.
Research graph
References from Advances in radiolabeled antibody technology: optimization strategies for precision medicine. Local targets link to admitted publications; unresolved targets remain external evidence.
Evaluation of candidate theranostics for227Th/89Zr paired radioimmunotherapy of lymphoma
10.2967/jnumed.122.264979 · 2023 · External reference
10.1080/19420862.2016.1185581
10.1080/19420862.2016.1185581 · External reference
Site-specific 89Zr- and 111In-radiolabeling and in vivo evaluation of glycan-free antibodies by azide–alkyne cycloaddition with a non-natural amino acid
10.1021/acs.bioconjchem.0c00100 · 2020 · External reference
Optimizing peptide nucleic acid-based pretargeting for enhanced targeted radionuclide therapy
10.1016/j.jconrel.2025.02.047 · 2025 · External reference
Intraperitoneal α-particle radioimmunotherapy of ovarian cancer patients: pharmacokinetics and dosimetry of 211At-MX35 F(ab′)2—A phase I study
10.2967/jnumed.109.062604 · 2009 · External reference
Zirconium 89 and copper 64 for ImmunoPET: from antibody bioconjugation and radiolabeling to molecular imaging
10.3390/pharmaceutics16070882 · 2024 · External reference
Synthesis and evaluation of anti-PD-L1-B11 antibody fragments for PET imaging of PD-L1 in breast cancer and melanoma tumor models
10.1038/s41598-024-70385-8 · 2024 · External reference
10.3390/ph11040132
10.3390/ph11040132 · External reference
89Zr-trastuzumab PET supports clinical decision making in breast cancer patients, when HER2 status cannot be determined by standard work up
10.1007/s00259-018-4099-8 · 2018 · External reference
Pilot study of 68Ga-DOTA-F(ab')2-trastuzumab in patients with breast cancer
10.1097/mnm.0b013e328365d99b · 2013 · External reference
Actinium-225 targeted alpha particle therapy for prostate cancer
10.7150/thno.96403 · 2024 · External reference
Unresolved reference
2016 · External reference
Synthesis and evaluation of HOPO-O8-methyl-tetrazine as a bifunctional chelator for use in [89Zr]Zr4+, [161Tb]Tb3+ and [227Th]Th4+ radioimmunoconjugates
10.1016/j.jinorgbio.2025.113077 · 2026 · External reference
124I-huA33 antibody PET of colorectal cancer
10.2967/jnumed.110.086165 · 2011 · External reference
Alpha radioimmunotherapy using 225Ac-proteus-DOTA for solid tumors - safety at curative doses
10.7150/thno.48810 · 2020 · External reference
Theranostic pretargeted radioimmunotherapy of internalizing solid tumor antigens in human tumor xenografts in mice: curative treatment of HER2-positive breast carcinoma
10.7150/thno.26585 · 2018 · External reference
Versatile bifunctional PYTA derivatives for 225Ac radiolabeling: a comparison to gold standards
10.2967/jnumed.125.270234 · 2025 · External reference
Optimized clinical performance of growth hormone with an expanded genetic code
10.1073/pnas.1100387108 · 2011 · External reference
Head-to-head comparison of dFO* and DFO chelators: selection of the best candidate for clinical 89Zr-immuno-PET
10.1007/s00259-020-05002-7 · 2021 · External reference
Toward personalized medicine: one chelator for imaging and therapy with lutetium-177 and actinium-225
10.1021/jacs.2c08438 · 2022 · External reference
Consensus nomenclature rules for radiopharmaceutical chemistry — setting the record straight
10.1016/j.nucmedbio.2017.09.004 · 2017 · External reference
10.1186/s41181-018-0047-y
10.1186/s41181-018-0047-y · External reference
10.2967/jnumed.120.255679
10.2967/jnumed.120.255679 · External reference
Site-specific photoaffinity bioconjugation for the creation of 89Zr-labeled radioimmunoconjugates
10.1007/s11307-023-01818-5 · 2023 · External reference
Radioactive drugs emerge from the shadows to storm the market
10.1038/nbt1218-1125 · 2018 · External reference
Perspectives on internal dosimetry for optimized radionuclide therapy
2022 · External reference
177Lu-PSMA-617 single-photon emission computed tomography/computed tomography dosimetry and radiobiological models demonstrate decreasing tumor-to-kidney dose ratio with successive cycles
10.1016/j.ijrobp.2025.06.3869 · 2025 · External reference
Phase 1 trial of a novel anti-CD20 fusion protein in pretargeted radioimmunotherapy for B-cell non-Hodgkin lymphoma
10.1182/blood-2003-09-3284 · 2004 · External reference
CD38-bispecific antibody pretargeted radioimmunotherapy for multiple myeloma and other B-cell malignancies
10.1182/blood-2017-09-807610 · 2018 · External reference
Report of a European consensus workshop to develop recommendations for the optimal use of 90Y-ibritumomab tiuxetan (Zevalin®) in lymphoma
10.1093/annonc/mdi148 · 2005 · External reference
Pretargeted immuno-PET of pancreatic cancer: overcoming circulating antigen and internalized antibody to reduce radiation doses
10.2967/jnumed.115.163824 · 2016 · External reference
Preliminary development and testing of c595 radioimmunoconjugates for targeting MUC1 cancer epitopes in pancreatic ductal adenocarcinoma
2022 · External reference
Site‐specific and stoichiometric modification of antibodies by bacterial transglutaminase
10.1002/anie.201004243 · 2010 · External reference
H2BZmacropa-NCS: a bifunctional chelator for actinium-225 targeted alpha therapy
10.1021/acs.bioconjchem.2c00190 · 2022 · External reference
Preclinical evaluation of NETA-based bifunctional ligand for radioimmunotherapy applications using 212Bi and 213Bi: radiolabeling, serum stability, and biodistribution and tumor uptake studies
10.1016/j.nucmedbio.2013.01.012 · 2013 · External reference
Dual radionuclide theranostic pretargeting
10.1021/acs.molpharmaceut.9b00746 · 2019 · External reference
Tumor targeting by a multivalent single-chain Fv (scFv) anti-lewis Y antibody construct
2008 · External reference
Scaling-down antibody radiolabeling reactions with zirconium-89
10.1039/c5dt04774a · 2016 · External reference
Phase 1/2a study of 177Lu-lilotomab satetraxetan in relapsed/refractory indolent non-hodgkin lymphoma
10.1182/bloodadvances.2020002583 · 2020 · External reference
Identifying CD38+ cells in patients with multiple myeloma: first-in-human imaging using copper-64–labeled daratumumab
10.1182/bloodadvances.2020002603 · 2020 · External reference
Site-specifically labeled 89Zr-DFO-trastuzumab improves immuno-reactivity and tumor uptake for immuno-PET in a subcutaneous HER2-positive xenograft mouse model
10.7150/thno.32883 · 2019 · External reference
PEGylation and multimerization of the anti-p185HER-2 single chain Fv fragment 4D5
10.1074/jbc.m604127200 · 2006 · External reference
Exploration of radionuclide labeling of a novel scFv-fc fusion protein targeting CLDN18.2 for tumor diagnosis and treatment
10.1016/j.ejmech.2024.116134 · 2024 · External reference
Site-specific conjugation of monodispersed DOTA-PEGn to a thiolated diabody reveals the effect of increasing peg size on kidney clearance and tumor uptake with improved 64-copper PET imaging
10.1021/bc100464e · 2011 · External reference
10.1021/acs.bioconjchem.0c00171
10.1021/acs.bioconjchem.0c00171 · External reference
Synthesis of novel DOTA-/AAZTA-based bifunctional chelators: solution thermodynamics, peptidomimetic conjugation, and radiopharmaceutical evaluation
10.1016/j.biopha.2023.115114 · 2023 · External reference
EGFR-targeted metal chelating polymers (MCPs) harboring multiple pendant PEG2K chains for MicroPET/CT imaging of patient-derived pancreatic cancer xenografts
10.1021/acsbiomaterials.6b00649 · 2017 · External reference
EANM guideline for harmonisation on molar activity or specific activity of radiopharmaceuticals: impact on safety and imaging quality
10.1186/s41181-021-00149-6 · 2021 · External reference
Unresolved reference
2018 · External reference
Fc-engineered monoclonal antibodies to reduce off-target liver uptake
10.1186/s13550-023-01030-0 · 2023 · External reference
Site-specific labeling of cysteine-tagged camelid single-domain antibody-fragments for use in molecular imaging
10.1021/bc500111t · 2014 · External reference
PET/CT and SPECT/CT imaging of HER2-positive breast cancer
10.3390/jcm12154882 · 2023 · External reference
Unresolved reference
2015 · External reference
First-in-human study of a thorium-227-labeled mesothelin-targeting antibody-chelator conjugate (MSLN-TTC), in patients with malignant mesothelioma and other solid tumors
10.1016/j.esmoop.2025.105905 · 2025 · External reference
Basic and practical concepts of radiopharmaceutical purification methods
10.1016/j.drudis.2018.09.018 · 2019 · External reference
Effect of modulating FcRn binding on direct and pretargeted tumor uptake of full-length antibodies
10.1158/1535-7163.mct-19-1015 · 2020 · External reference
Radioimmunotherapy: is avidin-biotin pretargeting the preferred choice among pretargeting methods?
10.1007/s00259-002-1090-0 · 2003 · External reference
Enzyme‐mediated site‐specific bioconjugation of metal complexes to proteins: sortase‐mediated coupling of copper‐64 to a single‐chain antibody
10.1002/anie.201402613 · 2014 · External reference
p-Isothiocyanatobenzyl-desferrioxamine: a new bifunctional chelate for facile radiolabeling of monoclonal antibodies with zirconium-89 for immuno-PET imaging
10.1007/s00259-009-1263-1 · 2009 · External reference
10.1016/j.bbcan.2021.188529
10.1016/j.bbcan.2021.188529 · External reference
Individualization of radionuclide therapies: challenges and prospects
10.3390/cancers14143418 · 2022 · External reference
Site-selective template-directed synthesis of antibody Fc conjugates with concomitant ligand release
10.1039/d3sc04324j · 2024 · External reference
Template directed synthesis of antibody Fc conjugates with concomitant ligand release
10.1039/d1sc06182h · 2022 · External reference
Predicting the response to CTLA-4 blockade by longitudinal noninvasive monitoring of CD8 T cells
10.1084/jem.20161950 · 2017 · External reference
90-yttrium-ibritumomab tiuxetan as first-line treatment for follicular lymphoma: updated efficacy and safety results at an extended median follow-up of 9.6 years
10.1007/s00277-022-04781-3 · 2022 · External reference
225Ac α-pretargeted radioimmunotherapy of human epidermal growth factor receptor 2–expressing breast cancer
10.2967/jnumed.125.269601 · 2025 · External reference
HER3 PET imaging: 68Ga-labeled affibody molecules provide superior HER3 contrast to 89Zr-labeled antibody and antibody-fragment-based tracers
10.3390/cancers13194791 · 2021 · External reference
Antibody engineering for nuclear imaging and radioimmunotherapy
10.2967/jnumed.122.263861 · 2022 · External reference
Site-specific covalent modification of monoclonal antibodies: in vitro and in vivo evaluations
10.1073/pnas.83.8.2632 · 1986 · External reference
Pretargeted radioimmunotherapy and SPECT imaging of peritoneal carcinomatosis using bioorthogonal click chemistry: probe selection and first proof-of-concept
10.7150/thno.35461 · 2019 · External reference
Sequential cytarabine and alpha-particle immunotherapy with bismuth-213-lintuzumab (HuM195) for acute myeloid leukemia
10.1158/1078-0432.ccr-10-0382 · 2010 · External reference
Highly reactive trans-cyclooctene tags with improved stability for diels–alder chemistry in living systems
10.1021/bc400153y · 2013 · External reference
GPA33-pretargeted radioimmunotherapy with mono- and bivalent DOTA-based Lu-177-labeled radiohaptens in a mouse orthotopic liver xenograft model of metastatic human colorectal cancer
10.7150/thno.107209 · 2025 · External reference
DFO-Km: a modular chelator as a new chemical tool for the construction of zirconium-89-based radiopharmaceuticals
10.1021/acs.inorgchem.3c02714 · 2023 · External reference
Synthesis and evaluation of bifunctional DFO2K: a modular chelator with ideal properties for zirconium-89 chelation
10.1039/d4dt01830c · 2024 · External reference
10.7150/thno.79976
10.7150/thno.79976 · External reference
Evaluation of 177Lu-labeled pertuzumab F(ab′) 2 fragments for HER2-positive cancer targeting: a comparative in vitro and in vivo study
2024 · External reference
A systematic evaluation of antibody modification and 89Zr-radiolabeling for optimized immuno-PET
10.1021/acs.bioconjchem.0c00087 · 2020 · External reference
Influence of Fc modifications and IgG subclass on biodistribution of humanized antibodies targeting L1CAM
10.2967/jnumed.121.262383 · 2022 · External reference
Nuclear medicine and wall street: an evolving relationship
10.2967/jnumed.118.220798 · 2019 · External reference
Development of a [89Zr]Zr-labeled human antibody using a novel phage-displayed human scFv library
10.1158/1078-0432.ccr-23-3647 · 2024 · External reference
Efficient bifunctional decadentate ligand 3p-C-DEPA for targeted α-radioimmunotherapy applications
10.1021/bc100586y · 2011 · External reference
EANM guidance document: dosimetry for first-in-human studies and early phase clinical trials
10.1007/s00259-024-06640-x · 2024 · External reference
New bifunctional chelator 3p-C-NEPA for potential applications in Lu(III) and Y(III) radionuclide therapy and imaging
10.1021/acsomega.0c03551 · 2020 · External reference
A phase I dose-escalation/expansion study of fractionated-dose and multiple cycle anti-PSMA-targeted alpha emitter 225Ac-J591 in patients with prostate cancer
2026 · External reference
Enhanced immunoPET of ALCAM-positive colorectal carcinoma using site-specific 64Cu-DOTA conjugation
10.1093/protein/gzu030 · 2014 · External reference
Localization, mechanism and reduction of renal retention of technetium‐99m labeled epidermal growth factor receptor‐specific nanobody in mice
10.1002/cmmi.408 · 2010 · External reference
10.1158/0008-5472.can-06-1630
10.1158/0008-5472.can-06-1630 · External reference
10.1021/acs.molpharmaceut.1c00841
10.1021/acs.molpharmaceut.1c00841 · External reference
The influence of glycans-specific bioconjugation on the FcγRI binding and in vivo performance of 89Zr-DFO-pertuzumab
10.7150/thno.39089 · 2020 · External reference
The impact of FcγRI binding on immuno-PET
10.2967/jnumed.118.223636 · 2019 · External reference
Understanding the in vivo fate of radioimmunoconjugates for nuclear imaging
10.1002/jlcr.3628 · 2018 · External reference
Radionuclide therapy of HER2-expressing human xenografts using affibody-based peptide nucleic acid–mediated pretargeting: in vivo proof of principle
10.2967/jnumed.118.208348 · 2018 · External reference
Shorter peptide nucleic acid probes improve affibody-mediated peptide nucleic acid-based pretargeting
10.1021/acsptsci.4c00106 · 2024 · External reference
Synthesis of site-specific radiolabeled antibodies for radioimmunotherapy via genetic code expansion
10.1021/acs.bioconjchem.6b00412 · 2016 · External reference
Good practices for (89)Zr radiopharmaceutical production and quality control
10.1186/s41181-024-00258-y · 2024 · External reference
10.2967/jnumed.112.111021
10.2967/jnumed.112.111021 · External reference
Harnessing α-emitting radionuclides for therapy: radiolabeling method review
10.2967/jnumed.121.262687 · 2022 · External reference
Enzyme-mediated methodology for the site-specific radiolabeling of antibodies based on catalyst-free click chemistry
10.1021/bc400122c · 2013 · External reference
Carrier systems of radiopharmaceuticals and the application in cancer therapy
2024 · External reference