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References from Stromal spatial signatures of the classical adenosine pathway dictate prognosis in hepatocellular carcinoma. Local targets link to admitted publications; unresolved targets remain external evidence.
Global Cancer statistics 2020: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries
2021 · External reference
Hepatocellular carcinoma
10.1016/s0140-6736(22)01200-4 · 2022 · External reference
The role of molecular enrichment on future therapies in hepatocellular carcinoma
10.1016/j.jhep.2018.02.016 · 2018 · External reference
Atezolizumab plus Bevacizumab in unresectable hepatocellular carcinoma
10.1056/nejmoa1915745 · 2020 · External reference
Nivolumab versus sorafenib in advanced hepatocellular carcinoma (CheckMate 459): a randomised, multicentre, open-label, phase 3 trial
10.1016/s1470-2045(21)00604-5 · 2022 · External reference
Advances in immunotherapy for hepatocellular carcinoma
10.1038/s41575-021-00438-0 · 2021 · External reference
Targeting metabolism to improve the tumor microenvironment for cancer immunotherapy
10.1016/j.molcel.2020.05.034 · 2020 · External reference
Multidimensional analyses reveal distinct immune microenvironment in hepatitis B virus-related hepatocellular carcinoma
10.1136/gutjnl-2018-316510 · 2019 · External reference
Current concepts of immune based treatments for patients with HCC: from basic science to novel treatment approaches
10.1136/gutjnl-2014-307990 · 2015 · External reference
Targeting immunosuppressive adenosine in cancer
10.1038/nrc.2017.86 · 2017 · External reference
Extracellular ATP and P2 purinergic signalling in the tumour microenvironment
10.1038/s41568-018-0037-0 · 2018 · External reference
CD39 and CD73 in immunity and inflammation
10.1016/j.molmed.2013.03.005 · 2013 · External reference
LAG3 (CD223) as a cancer immunotherapy target
10.1111/imr.12519 · 2017 · External reference
A2A adenosine receptor protects tumors from antitumor T cells
10.1073/pnas.0605251103 · 2006 · External reference
Targeting adenosine for cancer immunotherapy
10.1186/s40425-018-0360-8 · 2018 · External reference
Targeting CD39 in cancer
10.1038/s41577-020-0376-4 · 2020 · External reference
Landscape of infiltrating T cells in liver cancer revealed by single-cell sequencing
10.1016/j.cell.2017.05.035 · 2017 · External reference
Three-dimensional analysis of extrahepatic cholangiocarcinoma and tumor budding
10.1002/path.5474 · 2020 · External reference
CD73 promotes hepatocellular carcinoma progression and metastasis via activating PI3K/AKT signaling by inducing Rap1-mediated membrane localization of P110β and predicts poor prognosis
10.1186/s13045-019-0724-7 · 2019 · External reference
The BMP pathway and its inhibitors in the skeleton
10.1152/physrev.00028.2017 · 2018 · External reference
Purinergic regulation of the immune system
10.1038/nri.2016.4 · 2016 · External reference
Role of the carboxy-terminal transactivation domain and active transcription in the ligand-induced and ligand-independent degradation of the mouse ahb-1 receptor
10.1016/j.bcp.2005.09.006 · 2005 · External reference
The remarkable conformational plasticity of alpha-synuclein: blessing or curse?
10.1016/j.molmed.2013.04.002 · 2013 · External reference
Adenosine-A2A receptor pathway in cancer immunotherapy
2022 · External reference
HIF-dependent induction of adenosine A2B receptor in hypoxia
10.1096/fj.06-6419com · 2006 · External reference
Rescue of HIV-1 broad neutralizing antibody-expressing B cells in 2F5 VH x VL knockin mice reveals multiple tolerance controls
10.4049/jimmunol.1101633 · 2011 · External reference
TLR and nucleotide-binding oligomerization domain-like receptor signals differentially regulate exogenous antigen presentation
10.4049/jimmunol.1102214 · 2012 · External reference
Withdrawal notice to: adult hippocampal neurogenesis and antidepressants effects [COPHAR, 50 2020, 17-24]
10.1016/j.coph.2020.08.001 · 2020 · External reference
Adenosine-A2A receptor pathway in cancer immunotherapy
2022 · External reference
Spatial heterogeneity reveals an evolutionary signature predicting therapeutic response and clinical outcomes in hepatocellular carcinoma
10.3389/fbinf.2025.1669236 · 2025 · External reference
Single cell-spatial transcriptomics and bulk multi-omics analysis of heterogeneity and ecosystems in hepatocellular carcinoma
10.1038/s41698-024-00752-1 · 2024 · External reference
Moderate expression of CD39 in GPC3-CAR-T cells shows high efficacy against hepatocellular carcinoma
10.1007/s11684-024-1071-9 · 2024 · External reference
Activation of basal forebrain cholinergic neurons improves colonic hyperpermeability through the vagus nerve and adenosine A2B receptors in rats
10.1016/j.bcp.2022.115331 · 2022 · External reference
Enhancing extracellular adenosine levels restores barrier function in acute lung injury through expression of focal adhesion proteins
2021 · External reference
CD39 regulates P2RX7-mediated lung necrotic lesions in severe experimental tuberculosis
10.1016/j.mucimm.2026.03.007 · 2026 · External reference
Purinergic receptor nanoimmunoamplifiers potentiate chemoimmunotherapy efficacy in hepatocellular carcinoma
10.34133/bmr.0278 · 2025 · External reference
Extracellular ATP and adenosine: the yin and yang in immune responses?
10.1016/j.mam.2017.01.002 · 2017 · External reference
Metabolic reprogramming and cancer progression
2020 · External reference
Targeting CD73 enhances the antitumor activity of anti-PD-1 and anti-CTLA-4 mAbs
10.1158/1078-0432.ccr-13-0545 · 2013 · External reference
