Contact and support
Need help, have a question, or want to contact the ResearchHub team?
© 2026 ResearchHub. Built for responsible scholarly connection.
Privacy-aware community infrastructureResearch graph
References from Induced regulatory B cells stably expressing interleukin-10 reverse central nervous system autoimmunity by targeting myeloid cells. Local targets link to admitted publications; unresolved targets remain external evidence.
Are Regulatory T Cells Defective in Type 1 Diabetes and Can We Fix Them?
10.4049/jimmunol.1601118 · 2016 · External reference
Innovative trial approaches in immune-mediated inflammatory diseases: current use and future potential
10.1186/s41927-021-00192-5 · 2021 · External reference
B cells regulate autoimmunity by provision of IL-10
10.1038/ni833 · 2002 · External reference
Signaling via the MyD88 adaptor protein in B cells suppresses protective immunity during Salmonella typhimurium infection
10.1016/j.immuni.2010.10.016 · 2010 · External reference
A regulatory B cell subset with a unique CD1dhiCD5+ phenotype controls T cell-dependent inflammatory responses
10.1016/j.immuni.2008.03.017 · 2008 · External reference
Immune regulatory function of B cells
10.1146/annurev-immunol-020711-074934 · 2012 · External reference
Human regulatory B cells in health and disease: therapeutic potential
10.1172/jci85113 · 2017 · External reference
TLR-activated B cells suppress T cell-mediated autoimmunity
10.4049/jimmunol.180.7.4763 · 2008 · External reference
Distinct effector cytokine profiles of memory and naive human B cell subsets and implication in multiple sclerosis
10.4049/jimmunol.178.10.6092 · 2007 · External reference
Helminth infections associated with multiple sclerosis induce regulatory B cells
10.1002/ana.21438 · 2008 · External reference
Prevention of arthritis by interleukin 10-producing B cells
10.1084/jem.20021293 · 2003 · External reference
Chronic intestinal inflammatory condition generates IL-10-producing regulatory B cell subset characterized by CD1d upregulation
10.1016/s1074-7613(02)00274-1 · 2002 · External reference
B cell-derived IL-10 suppresses inflammatory disease in Lyn-deficient mice
10.1073/pnas.1107913108 · 2011 · External reference
Activation of CD4+ Foxp3+ regulatory T cells proceeds normally in the absence of B cells during EAE
10.1002/eji.201142242 · 2012 · External reference
Csf1R inhibition attenuates experimental autoimmune encephalomyelitis and promotes recovery
10.1016/j.expneurol.2018.05.021 · 2018 · External reference
Mannan-MOG35-55 Reverses Experimental Autoimmune Encephalomyelitis, Inducing a Peripheral Type 2 Myeloid Response, Reducing CNS Inflammation, and Preserving Axons in Spinal Cord Lesions
10.3389/fimmu.2020.575451 · 2020 · External reference
Myeloid cell replacement is neuroprotective in chronic experimental autoimmune encephalomyelitis
10.1038/s41593-024-01609-3 · 2024 · External reference
Characterization of three CpG oligodeoxynucleotide classes with distinct immunostimulatory activities
10.1002/eji.200324032 · 2004 · External reference
B cell depletion therapy ameliorates autoimmune disease through ablation of IL-6-producing B cells
10.1084/jem.20111675 · 2012 · External reference
B cell-derived IL-6 initiates spontaneous germinal center formation during systemic autoimmunity
10.1084/jem.20170580 · 2017 · External reference
IL-35-producing B cells are critical regulators of immunity during autoimmune and infectious diseases
10.1038/nature12979 · 2014 · External reference
The special unfolded protein response in plasma cells
10.1111/imr.13012 · 2021 · External reference
Serum neurofilament light chain for individual prognostication of disease activity in people with multiple sclerosis: a retrospective modelling and validation study
10.1016/s1474-4422(22)00009-6 · 2022 · External reference
Microglia and Central Nervous System-Associated Macrophages-From Origin to Disease Modulation
10.1146/annurev-immunol-093019-110159 · 2021 · External reference
Microglia Biology: One Century of Evolving Concepts
10.1016/j.cell.2019.08.053 · 2019 · External reference
Single-cell profiling identifies myeloid cell subsets with distinct fates during neuroinflammation
10.1126/science.aat7554 · 2019 · External reference
MIIC online: a web server to reconstruct causal or non-causal networks from non-perturbative data
10.1093/bioinformatics/btx844 · 2018 · External reference
Transgenic Targeting of Fcrls Creates a Highly Efficient Constitutively Active Microglia Cre Line with Differentiated Specificity
10.1523/eneuro.0549-23.2024 · 2024 · External reference
Single-cell transcriptomics reveals distinct inflammation-induced microglia signatures
10.15252/embr.201846171 · 2018 · External reference
Dual ontogeny of disease-associated microglia and disease inflammatory macrophages in aging and neurodegeneration
10.1016/j.immuni.2022.07.004 · 2022 · External reference
Single-Cell RNA Sequencing of Microglia throughout the Mouse Lifespan and in the Injured Brain Reveals Complex Cell-State Changes
10.1016/j.immuni.2018.11.004 · 2019 · External reference
A Unique Microglia Type Associated with Restricting Development of Alzheimer’s Disease
10.1016/j.cell.2017.05.018 · 2017 · External reference
A single-cell atlas of mouse brain macrophages reveals unique transcriptional identities shaped by ontogeny and tissue environment
10.1038/s41593-019-0393-4 · 2019 · External reference
The P2Y12 receptor regulates microglial activation by extracellular nucleotides
10.1038/nn1805 · 2006 · External reference
Differential roles of microglia and monocytes in the inflamed central nervous system
10.1084/jem.20132477 · 2014 · External reference
Infiltrating monocytes trigger EAE progression, but do not contribute to the resident microglia pool
10.1038/nn.2887 · 2011 · External reference
CCR2+Ly-6Chi monocytes are crucial for the effector phase of autoimmunity in the central nervous system
10.1093/brain/awp144 · 2009 · External reference
Interleukin-10 Prevents Pathological Microglia Hyperactivation following Peripheral Endotoxin Challenge
10.1016/j.immuni.2020.09.018 · 2020 · External reference
Origin, fate and dynamics of macrophages at central nervous system interfaces
10.1038/ni.3423 · 2016 · External reference
B cells in multiple sclerosis - from targeted depletion to immune reconstitution therapies
10.1038/s41582-021-00498-5 · 2021 · External reference
Rat and human myelin oligodendrocyte glycoproteins induce experimental autoimmune encephalomyelitis by different mechanisms in C57BL/6 mice
10.4049/jimmunol.171.1.462 · 2003 · External reference
Interleukin-10-producing plasmablasts exert regulatory function in autoimmune inflammation
10.1016/j.immuni.2014.10.016 · 2014 · External reference
Recirculating Intestinal IgA-Producing Cells Regulate Neuroinflammation via IL-10
10.1016/j.cell.2019.03.037 · 2019 · External reference
LAG-3 Inhibitory Receptor Expression Identifies Immunosuppressive Natural Regulatory Plasma Cells
10.1016/j.immuni.2018.06.007 · 2018 · External reference
Immunosuppressive plasma cells impede T-cell-dependent immunogenic chemotherapy
10.1038/nature14395 · 2015 · External reference
Inflammation-induced IgA+ cells dismantle anti-liver cancer immunity
10.1038/nature24302 · 2017 · External reference
The compartmentalized inflammatory response in the multiple sclerosis brain is composed of tissue-resident CD8+ T lymphocytes and B cells
10.1093/brain/awy151 · 2018 · External reference
Gut microbiota-specific IgA+ B cells traffic to the CNS in active multiple sclerosis
10.1126/sciimmunol.abc7191 · 2020 · External reference
Microglia: Immune and non-immune functions
10.1016/j.immuni.2021.09.014 · 2021 · External reference
Microglia and meningeal macrophages depletion delays the onset of experimental autoimmune encephalomyelitis
10.1038/s41419-023-05551-3 · 2023 · External reference
Reduction of microglial activity in a model of multiple sclerosis by dipyridamole
10.1186/1742-2094-10-89 · 2013 · External reference
A new type of microglia gene targeting shows TAK1 to be pivotal in CNS autoimmune inflammation
10.1038/nn.3531 · 2013 · External reference
Experimental autoimmune encephalomyelitis repressed by microglial paralysis
10.1038/nm1177 · 2005 · External reference
The TREM2-APOE Pathway Drives the Transcriptional Phenotype of Dysfunctional Microglia in Neurodegenerative Diseases
10.1016/j.immuni.2017.08.008 · 2017 · External reference
Microglia promote autoimmune inflammation via the noncanonical NF-κB pathway
10.1126/sciadv.abh0609 · 2021 · External reference
Microglia-specific IL-10 gene delivery inhibits neuroinflammation and neurodegeneration in a mouse model of Parkinson’s disease
10.1126/scitranslmed.adm8563 · 2024 · External reference
Targeting immune cells in the aged brain reveals that engineered cytokine IL-10 enhances neurogenesis and improves cognition
10.1016/j.immuni.2026.01.016 · 2026 · External reference
IL-10 fails to abrogate experimental autoimmune encephalomyelitis
10.1002/(sici)1097-4547(19960915)45:6<735::aid-jnr10>3.0.co;2-v · 1996 · External reference
The therapeutic potential of interleukin-10 in neuroimmune diseases
10.1016/j.neuropharm.2014.10.020 · 2015 · External reference
Macrophage-restricted interleukin-10 receptor deficiency, but not IL-10 deficiency, causes severe spontaneous colitis
10.1016/j.immuni.2014.03.012 · 2014 · External reference
Macrophage dysfunction initiates colitis during weaning of infant mice lacking the interleukin-10 receptor
10.7554/elife.27652 · 2017 · External reference
In vitro immunization of naive mouse B cells: establishment of IgM secreting hybridomas specific for souble protein or hapten from B cells cultured on CD40 ligand transfected mouse fibroblasts
10.1093/intimm/8.3.343 · 1996 · External reference
Pancreatic cancer modeling using retrograde viral vector delivery and in vivo CRISPR/Cas9-mediated somatic genome editing
10.1101/gad.264861.115 · 2015 · External reference
Efficient CRISPR-mediated mutagenesis in primary immune cells using CrispRGold and a C57BL/6 Cas9 transgenic mouse line
10.1073/pnas.1613884113 · 2016 · External reference
CellPhoneDB: inferring cell-cell communication from combined expression of multi-subunit ligand-receptor complexes
10.1038/s41596-020-0292-x · 2020 · External reference
Biology-inspired data-driven quality control for scientific discovery in single-cell transcriptomics
10.1186/s13059-022-02820-w · 2022 · External reference
decoupleR: ensemble of computational methods to infer biological activities from omics data
10.1093/bioadv/vbac016 · 2022 · External reference
Gene Set Knowledge Discovery with Enrichr
10.1002/cpz1.90 · 2021 · External reference
Fast, sensitive and accurate integration of single-cell data with Harmony
10.1038/s41592-019-0619-0 · 2019 · External reference
Modular, efficient and constant-memory single-cell RNA-seq preprocessing
10.1038/s41587-021-00870-2 · 2021 · External reference
Clustering trees: a visualization for evaluating clusterings at multiple resolutions
10.1093/gigascience/giy083 · 2018 · External reference
Learning clinical networks from medical records based on information estimates in mixed-type data
10.1371/journal.pcbi.1007866 · 2020 · External reference
Learning causal networks with latent variables from multivariate information in genomic data
10.1371/journal.pcbi.1005662 · 2017 · External reference
The Molecular Signatures Database (MSigDB) hallmark gene set collection
10.1016/j.cels.2015.12.004 · 2015 · External reference
NicheNet: modeling intercellular communication by linking ligands to target genes
10.1038/s41592-019-0667-5 · 2020 · External reference
NIH Image to ImageJ: 25 years of image analysis
10.1038/nmeth.2089 · 2012 · External reference
Single-cell normalization and association testing unifying CRISPR screen and gene co-expression analyses with Normalisr
2021 · External reference
pRESTO: a toolkit for processing high-throughput sequencing raw reads of lymphocyte receptor repertoires
10.1093/bioinformatics/btu138 · 2014 · External reference
SCANPY: large-scale single-cell gene expression data analysis
10.1186/s13059-017-1382-0 · 2018 · External reference
Doublet identification in single-cell sequencing data using scDblFinder
10.12688/f1000research.73600.1 · 2021 · External reference
Integrated analysis of multimodal single-cell data
10.1016/j.cell.2021.04.048 · 2021 · External reference
Spatial reconstruction of single-cell gene expression data
10.1038/nbt.3192 · 2015 · External reference
Orchestrating single-cell analysis with Bioconductor
10.1038/s41592-019-0654-x · 2020 · External reference
SoupX removes ambient RNA contamination from droplet-based single-cell RNA sequencing data
10.1093/gigascience/giaa151 · 2020 · External reference
Agouti C57BL/6N embryonic stem cells for mouse genetic resources
10.1038/nmeth.1342 · 2009 · External reference
Guidelines for the use of flow cytometry and cell sorting in immunological studies (third edition)
10.1002/eji.202170126 · 2021 · External reference
Automated mapping of phenotype space with single-cell data
10.1038/nmeth.3863 · 2016 · External reference
Aging induces aberrant state transition kinetics in murine muscle stem cells
2020 · External reference
Interactive exploration of a global clinical network from a large breast cancer cohort
10.1038/s41746-022-00647-0 · 2022 · External reference
Determining immunoglobulin-specific B cell receptor repertoire of murine splenocytes by next-generation sequencing
10.1016/j.xpro.2022.101277 · 2022 · External reference
Change-O: a toolkit for analyzing large-scale B cell immunoglobulin repertoire sequencing data
10.1093/bioinformatics/btv359 · 2015 · External reference
Analyzing microglial phenotypes across neuropathologies: a practical guide
10.1007/s00401-021-02370-8 · 2021 · External reference
