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References from Screening of phytochemicals from Withania somnifera, Rauwolfia serpentina, Curcuma longa, and Camellia sinensis for potential maltase-glucoamylase (MGAM) inhibition using molecular docking, molecular dynamics simulation, and ADMET analysis. Local targets link to admitted publications; unresolved targets remain external evidence.
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An overview on the role of bioactive α-glucosidase inhibitors in ameliorating diabetic complications
10.1016/j.fct.2020.111738 · 2020 · External reference
α-Glucosidase inhibition mechanism and anti-hyperglycemic effects of flavonoids from astragali radix and their mixture effects
10.3390/ph18050744 · 2025 · External reference
Alpha-glucosidase inhibitors for type 2 diabetes mellitus
2005 · External reference
Effects of alpha-glucosidase-inhibiting drugs on acute postprandial glucose and insulin responses: a systematic review and meta-analysis
10.1038/s41387-021-00152-5 · 2021 · External reference
A review of alpha-glucosidase inhibitors from plants as potential candidates for the treatment of type-2 diabetes
10.1007/s11101-021-09773-1 · 2022 · External reference
Indian traditional medicinal plants as a source of potent anti-diabetic agents: a review
10.1007/s40200-020-00628-8 · 2020 · External reference
Screening of antioxidant and α-glucosidase inhibitory activities of indian medicinal plants
10.2174/1573408016666200414153108 · 2020 · External reference
Molecular docking as a tool for the discovery of molecular targets of nutraceuticals in diseases management
10.1038/s41598-023-40160-2 · 2023 · External reference
Applications of molecular docking in natural products-based drug discovery
2023 · External reference
AVPCD: a plant-derived medicine database of antiviral phytochemicals for cancer, Covid-19, malaria and HIV
10.1093/database/baad056 · 2023 · External reference
Methanolic root extract of rauwolfia serpentina benth improves the glycemic, antiatherogenic, and cardioprotective indices in alloxan-induced diabetic mice
2012 · External reference
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In vitro antidiabetic and inhibitory potential of turmeric (Curcuma longa L) rhizome against cellular and LDL oxidation and angiotensin converting enzyme
10.1007/s13197-013-0953-7 · 2014 · External reference
10.3390/foods2023-15514
10.3390/foods2023-15514 · External reference
Tea plant (Camellia sinensis): a current update on use in diabetes, obesity, and cardiovascular disease
10.3390/nu15010037 · 2022 · External reference
Antidiabetic actions of ethanol extract of camellia sinensis leaf ameliorates insulin secretion, inhibits the DPP-IV enzyme, improves glucose tolerance, and increases active GLP-1 (7–36) Levels in High-Fat-Diet-Fed Rats
10.3390/medicines9110056 · 2022 · External reference
Anti-inflammatory and anti-diabetic role of Ashwagandha (Withania somnifera) in a type 2 diabetes mellitus mouse model: a study using histological, molecular, and pathological parameters
10.1007/s00709-025-02096-4 · 2026 · External reference
Ashwagandha withanolides, Withaferin-A, and Withanone for natural interventions in aging and obesity
10.1016/j.mad.2025.112126 · 2025 · External reference
A comprehensive review on the therapeutic potential of curcuma longa linn. In relation to its major active constituent curcumin
10.3389/fphar.2022.820806 · 2022 · External reference
Beneficial effects of green tea: a literature review
10.1186/1749-8546-5-13 · 2010 · External reference
Anticancer therapeutic effects of green tea catechins (GTCs) when integrated with antioxidant natural components
10.3390/molecules28052151 · 2023 · External reference
A review on phytochemical, pharmacological and therapeutic effects of Rauvolfia serpentina
10.22271/phyto.2025.v14.i3d.15375 · 2025 · External reference
Enhancing anticancer activity of Clerodendrum viscosum vent. extracts by solvent fractionation: an in vitro and in silico mechanistic study
10.1016/j.procbio.2024.07.007 · 2024 · External reference
A computational approach to fighting type 1 diabetes by targeting 2C Coxsackie B virus protein with flavonoids
10.1371/journal.pone.0290576 · 2023 · External reference
Making it rain: cloud-based molecular simulations for everyone
10.1021/acs.jcim.1c00998 · 2021 · External reference
Targeting N-Terminal human maltase-glucoamylase to unravel possible inhibitors using molecular docking, molecular dynamics simulations, and adaptive steered molecular dynamics simulations
10.3389/fchem.2021.711242 · 2021 · External reference
Structural studies of the intestinal α-Glucosidases, Maltase-glucoamylase and Sucrase-isomaltase
2018 · External reference
<scp>Withania somnifera </scp>(Indian ginseng) in diabetes mellitus: a systematic review and meta-analysis of scientific evidence from experimental research to clinical application
10.1002/ptr.6589 · 2020 · External reference
Hypoglycaemic and Hypolipidaemic effects of Withania Somnifera root and leaf extracts on alloxan-induced diabetic rats
10.3390/ijms10052367 · 2009 · External reference
Protective effects of Withania somnifera root on inflammatory markers and insulin resistance in fructose-fed rats
2015 · External reference
Rauwolfia serpentina ameliorates hyperglycemic, haematinic and antioxidant status in alloxan- induced diabetic mice
2013 · External reference
Double-blind, crossover study comparing the bioavailability of 4 Ashwagandha (Withania somnifera (L.) Dunal) extracts in healthy adults under fasting condition
10.1016/j.curtheres.2025.100805 · 2025 · External reference
Clinical safety and tolerability evaluation of Withania somnifera (L.) Dunal (Ashwagandha) root extract in healthy human volunteers
10.1016/j.jaim.2023.100859 · 2024 · External reference
Safety of ashwagandha root extract: a randomized, placebo-controlled, study in healthy volunteers
10.1016/j.ctim.2020.102642 · 2021 · External reference
Sub-acute toxicity of Ashwagandha (Withania somnifera) root extract in Wistar rats
10.1016/j.toxrep.2023.10.009 · 2023 · External reference
