Research graph
References from Non-canonical Wnt11/PCP/YAP signaling mediates epithelial-mesenchymal transition and immunosuppressive tumor microenvironment in colorectal cancer. Local targets link to admitted publications; unresolved targets remain external evidence.
Colorectal cancer
10.1016/s0140-6736(24)00360-x · 2024 · External reference
The rising tide of early-onset colorectal cancer: a comprehensive review of epidemiology, clinical features, biology, risk factors, prevention, and early detection
10.1016/s2468-1253(21)00426-x · 2022 · External reference
Diagnosis and treatment of metastatic colorectal cancer: a review
10.1001/jama.2021.0106 · 2021 · External reference
Screening for colorectal cancer
10.7326/aitc202404160 · 2024 · External reference
Mechanisms of metastatic colorectal cancer
10.1038/s41575-024-00934-z · 2024 · External reference
Signaling pathways involved in colorectal cancer: pathogenesis and targeted therapy
2024 · External reference
Interplay between signaling pathways and tumor microenvironment components: a paradoxical role in colorectal cancer
10.3390/ijms24065600 · 2023 · External reference
The role of tumor microenvironment and immune response in colorectal cancer development and prognosis
10.3389/pore.2022.1610502 · 2022 · External reference
Tumor microenvironment shapes colorectal cancer progression, metastasis, and treatment responses
2022 · External reference
International validation of the consensus immunoscore for the classification of colon cancer: a prognostic and accuracy study
10.1016/s0140-6736(18)30789-x · 2018 · External reference
The consensus molecular subtypes of colorectal cancer
10.1038/nm.3967 · 2015 · External reference
Wnt signaling in colorectal cancer: pathogenic role and therapeutic target
10.1186/s12943-022-01616-7 · 2022 · External reference
Therapeutic targeting of the oncogenic Wnt signaling pathway for treating colorectal cancer and other colonic disorders
10.1016/j.addr.2020.12.010 · 2021 · External reference
Canonical and noncanonical Wnt signaling: multilayered mediators, signaling mechanisms and major signaling crosstalk
10.1016/j.gendis.2023.01.030 · 2024 · External reference
The involvement of noncanonical Wnt signaling in cancers
10.1016/j.biopha.2020.110946 · 2021 · External reference
Wnt/PCP signaling contribution to carcinoma collective cell migration and metastasis
10.1158/0008-5472.can-18-2757 · 2019 · External reference
Hippo pathway in organ size control, tissue homeostasis, and cancer
10.1016/j.cell.2015.10.044 · 2015 · External reference
YAP/TAZ as master regulators in cancer: modulation, function and therapeutic approaches
2023 · External reference
New insights into the Hippo/YAP pathway in idiopathic pulmonary fibrosis
10.1016/j.phrs.2021.105635 · 2021 · External reference
Cellular mechanotransduction in health and diseases: from molecular mechanism to therapeutic targets
10.1038/s41392-023-01501-9 · 2023 · External reference
Wnt-11 as a potential prognostic biomarker and therapeutic target in colorectal cancer
10.3390/cancers11070908 · 2019 · External reference
Metascape provides a biologist-oriented resource for the analysis of systems-level datasets
2019 · External reference
TIMER2.0 for analysis of tumor-infiltrating immune cells
10.1093/nar/gkaa407 · 2020 · External reference
Untangling the role of RhoA in the heart: protective effect and mechanism
10.1038/s41419-024-06928-8 · 2024 · External reference
Role of epithelial to mesenchymal transition in colorectal cancer
10.3390/ijms241914815 · 2023 · External reference
CXCL8 induces M2 macrophage polarization and inhibits CD8 (+) T cell infiltration to generate an immunosuppressive microenvironment in colorectal cancer
10.1096/fj.202201982rrr · 2023 · External reference
Investigating the anti-inflammatory effects of icariin: a combined meta-analysis and machine learning study
10.1016/j.heliyon.2024.e35307 · 2024 · External reference
The efficacy and toxicity equilibrium of emodin for liver injury: a bidirectional meta-analysis and machine learning
10.1016/j.phymed.2025.156650 · 2025 · External reference
Tumor-associated macrophage-specific CD155 contributes to M2-phenotype transition, immunosuppression, and tumor progression in colorectal cancer
10.1136/jitc-2021-004219 · 2022 · External reference
The role of CD8+ T-cells in colorectal cancer immunotherapy
10.1016/j.heliyon.2024.e33144 · 2024 · External reference
Identification of differentially expressed genes and splicing events in early-onset colorectal cancer
10.3389/fonc.2024.1365762 · 2024 · External reference
WNT11 promotes immune evasion and resistance to anti-PD-1 therapy in liver metastasis
10.1038/s41467-025-56714-z · 2025 · External reference
Hedyotis diffusa-Sculellaria barbata (HD-SB) suppresses the progression of colorectal cancer cells via the hsa_circ_0039933/hsa-miR-204-5p/wnt11 axis
10.1038/s41598-023-40393-1 · 2023 · External reference
ROCK inhibitor Y27632 induced morphological shift and enhanced neurite outgrowth-promoting property of olfactory ensheathing cells via YAP-dependent up-regulation of L1-CAM
10.3389/fncel.2018.00489 · 2018 · External reference
Influence of perioperative anaesthetic and analgesic interventions on oncological outcomes: a narrative review
10.1016/j.bja.2019.04.062 · 2019 · External reference
Immunomodulatory and pro-oncologic effects of ketamine and isoflurane anesthetics in a murine model
10.1371/journal.pone.0292492 · 2023 · External reference
