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References from Liver-specific sustained activation of the LPS/TLR4/NF-κB pathway: from a gut-liver axis hub to cascading extensions in reproductive and neuroinflammation. Local targets link to admitted publications; unresolved targets remain external evidence.
Bisphenol P triggers hepatic injury via gut microbiota dysbiosis-induced intestinal barrier disruption
10.1016/j.jenvman.2026.128773 · 2026 · External reference
Oryzanol ameliorates MCD-induced metabolic dysfunction-associated steatohepatitis in mice via gut microbiota reprogramming and TLR4/NF-κB signaling suppression
10.1152/ajpgi.00190.2024 · 2025 · External reference
Gut microbiota and neuroinflammation in acute liver failure and chronic liver disease
10.3390/metabo13060772 · 2023 · External reference
Yak milk ameliorates chronic alcohol-induced brain injury in mice by modulating the gut microbiota and suppressing the TLR4/NF-κB pathway
10.1039/d5fo03000e · 2025 · External reference
Toll-like receptor 4 inhibition by pyridostigmine is associated with a reduction in hypertension and inflammation in rat models of preeclampsia
10.1097/hjh.0000000000003911 · 2025 · External reference
Targeting the TLR4/NF-κB pathway in β-amyloid-stimulated microglial cells: a possible mechanism that oxysophoridine exerts anti-oxidative and anti-inflammatory effects in an in vitro model of Alzheimer’s disease
10.1016/j.brainresbull.2021.07.019 · 2021 · External reference
Dendrobine and Erianin alleviate inflammation-induced depressive-like behaviors by targeting phosphodiesterase 4B in adolescent mice
10.1016/j.phymed.2025.157230 · 2025 · External reference
From gut to liver: exploring the crosstalk between gut-liver axis and oxidative stress in metabolic dysfunction-associated steatotic liver disease
10.1016/j.aohep.2025.101777 · 2025 · External reference
Gut dysbiosis correction contributes to the hepatoprotective effects of Thymus quinquecostatus Celak extract against alcohol through the gut-liver axis
10.1039/d1fo01117k · 2021 · External reference
Apolipoprotein A-I: potential protection against intestinal injury induced by dietary lipid
10.2147/jir.s468842 · 2024 · External reference
LCA and 3-oxo-LCA mitigate dietary oxysterols-induced loss of barrier function in intestinal epithelial cells
10.1016/j.steroids.2026.109749 · 2026 · External reference
Impact of micro- and nanoplastics on gastrointestinal diseases: recent advances
10.1016/j.ejim.2025.07.015 · 2025 · External reference
Effects of cholesterol-lowering probiotics on non-alcoholic fatty liver disease in FXR gene knockout mice
10.3389/fnut.2023.1121203 · 2023 · External reference
Gut microbiome in non-alcoholic fatty liver disease
2024 · External reference
Microbiome-mediated crosstalk between T2DM and MASLD: a translational review focused on function
10.3389/fendo.2025.1677175 · 2025 · External reference
Endotoxemia and platelets: 2 players of intrahepatic microthrombosis in NAFLD
10.1016/j.jacbts.2023.07.003 · 2024 · External reference
Bovine colostrum-derived extracellular vesicles protect against non-alcoholic steatohepatitis by modulating gut microbiota and enhancing gut barrier function
10.1016/j.crfs.2025.101039 · 2025 · External reference
Role of NLRP3 in the metabolism of bile acids and gut microbiota in CCl4-induced liver fibrosis
10.1128/spectrum.00148-25 · 2025 · External reference
Mechanism of legionella pneumophila-induced liver injury via gut microbiota translocation under immunosuppression
10.1016/j.prp.2026.156456 · 2026 · External reference
Hepatic injury and ileitis associated with gut microbiota dysbiosis in mice upon F-53B exposure
10.1016/j.envres.2024.118305 · 2024 · External reference
Lipopolysaccharide, arbiter of the gut-liver axis, modulates hepatic cell pathophysiology in alcoholism
10.1002/ar.25562 · 2025 · External reference
Niloticin binds to MD-2 to promote anti-inflammatory pathway activation in macrophage cells
10.1177/03946320221133017 · 2022 · External reference
Blumeatin inhibits LPS-induced inflammation of TLR4/NF-κB signaling pathway via targeting TLR4/MD-2
10.1080/10286020.2025.2469690 · 2025 · External reference
Metformin inhibits microglial activation-mediated Cuproptosis by modulating the TLR4/Myd88/NF-κB Signaling pathway in Parkinson’s disease
10.1007/s12035-025-05499-9 · 2025 · External reference
Pectolinarin alleviates inflammatory injury in a lipopolysaccharide-induced pneumonia model by inhibition of the TLR4/MyD88/NF-κB pathway
10.1016/j.tice.2026.103429 · 2026 · External reference
Aloperine suppresses LPS-induced macrophage activation through inhibiting the TLR4/NF-κB pathway
10.1007/s00011-019-01313-0 · 2020 · External reference
Advances in understanding lipopolysaccharide-mediated hepatitis: mechanisms and pathological features
10.3390/cimb47020079 · 2025 · External reference
Thyme (Thymus quinquecostatus Celak) polyphenol-rich extract (TPE) alleviates HFD-induced liver injury in mice by inactivating the TLR4/NF-κB Signaling pathway through the gut-liver Axis
10.3390/foods12163074 · 2023 · External reference
Protective effects of microbiome-derived inosine on lipopolysaccharide-induced acute liver damage and inflammation in mice via mediating the TLR4/NF-κB pathway
10.1021/acs.jafc.1c01781 · 2021 · External reference
Artemisia ordosica polysaccharide alleviated lipopolysaccharide-induced oxidative stress of broilers via Nrf2/Keap1 and TLR4/NF-κB pathway
10.1016/j.ecoenv.2021.112566 · 2021 · External reference
Qingrequzhuo capsule alleviated methionine and choline deficient diet-induced nonalcoholic steatohepatitis in mice through regulating gut microbiota, enhancing gut tight junction and inhibiting the activation of TLR4/NF-κB signaling pathway
2022 · External reference
Hepatocyte-conditional knockout of phosphatidylethanolamine binding protein 4 aggravated LPS/D-GalN-induced acute liver injury via the TLR4/NF-κB pathway
10.3389/fimmu.2022.901566 · 2022 · External reference
Molecular mechanism of anti-inflammatory effects of the proteasome inhibitor MG-132 on con A-induced acute liver injury in mice
10.1016/j.rvsc.2023.01.021 · 2023 · External reference
Enoxaparin sodium bone cement plays an anti-inflammatory immunomodulatory role by inducing the polarization of M2 macrophages
10.1186/s13018-023-03865-8 · 2023 · External reference
Histone methyltransferase SMYD2 regulates the activation of hepatic stellate cells by activating TLR4 signaling
2025 · External reference
10.12659/msm.931143
10.12659/msm.931143 · External reference
Dendrobium officinale alleviates high-fat diet-induced nonalcoholic steatohepatitis by modulating gut microbiota
10.3389/fcimb.2023.1078447 · 2023 · External reference
10.1007/s00203-026-04720-0
10.1007/s00203-026-04720-0 · External reference
Hic-5 deficiency attenuates hepatic ischemia reperfusion injury through TLR4/NF-κB signaling pathways
10.1016/j.lfs.2020.117517 · 2020 · External reference
10.1002/alz.71243
10.1002/alz.71243 · External reference
Toll-like receptor 4 (TLR4)/opioid receptor pathway crosstalk and impact on opioid analgesia, immune function, and gastrointestinal motility
10.3389/fimmu.2020.01455 · 2020 · External reference
Integrative analysis of lncRNAs in rheumatoid arthritis: from bioinformatics to experimental validation
10.1007/s10238-025-01589-z · 2025 · External reference
Acetylation of p65(Lys310) by p300 in macrophages mediates anti-inflammatory property of berberine
10.1016/j.redox.2023.102704 · 2023 · External reference
Nicotinamide mononucleotide alleviates endotoxin-induced acute lung injury by modulating macrophage polarization via the SIRT1/NF-κB pathway
10.1080/13880209.2023.2292256 · 2024 · External reference
Engineered exosome-mediated delivery of MicroRNA let-7i-5p targets toll-like receptor 4 to modulate inflammation and alleviate acute liver injury in septic mice
10.1016/j.intimp.2025.115827 · 2026 · External reference
Lack of association of the 3’-UTR polymorphism in the NFKBIA gene with Crohn’s disease in an Israeli cohort
10.1007/s00384-007-0287-x · 2007 · External reference
Hydrochlorothiazide-induced glucose metabolism disorder is mediated by the gut microbiota via LPS-TLR4-related macrophage polarization
10.1016/j.isci.2023.107130 · 2023 · External reference
Reprogramming macrophage metabolism and its effect on NLRP3 inflammasome activation in Sepsis
10.3389/fmolb.2022.917818 · 2022 · External reference
Goose deoxycholic acid ameliorates liver injury in laying hens with fatty liver Hemorrhage syndrome by inhibiting the inflammatory response
2025 · External reference
Beyond the brain: exploring the multi-organ axes in Parkinson’s disease pathogenesis
10.1016/j.jare.2025.05.034 · 2026 · External reference
Suboptimal thermal storage facilitates aging of bottle-sourced polyethylene terephthalate microplastics Fueling hepatic steatosis through gut-liver Axis disruption
10.1021/acs.est.5c18229 · 2026 · External reference
Akkermansia muciniphila attenuates LPS-induced acute kidney injury by inhibiting TLR4/NF-κB pathway
10.1093/femsle/fnac103 · 2022 · External reference
Circulating Interleukin-6 mediates PM(2.5)-induced ovarian injury by suppressing the PPARγ pathway
2024 · External reference
Acute-phase protein synthesis: a key feature of innate immune functions of the liver
10.1515/hsz-2021-0209 · 2021 · External reference
VCAM-1 in cognitive impairment: mechanisms, biomarker potential, and therapeutic targeting
2025 · External reference
10.1186/s12974-023-02817-7
10.1186/s12974-023-02817-7 · External reference
Trans-anethole ameliorates LPS-induced inflammation via suppression of TLR4/NF-κB pathway in IEC-6 cells
10.1016/j.intimp.2022.108872 · 2022 · External reference
Hyodeoxycholic acid ameliorates nonalcoholic fatty liver disease by inhibiting RAN-mediated PPARα nucleus-cytoplasm shuttling
10.1038/s41467-023-41061-8 · 2023 · External reference
Recent advances in the medicinal chemistry of Farnesoid X receptor
10.1021/acs.jmedchem.1c01017 · 2021 · External reference
Linking liver metabolic and vascular disease via bile acid signaling
10.1016/j.molmed.2021.10.005 · 2022 · External reference
Bile acid metabolism regulates ovarian function: networks and reproductive health applications
10.1017/erm.2026.10035 · 2026 · External reference
L-kynurenine activates the AHR-PCSK9 pathway to mediate the lipid metabolic and ovarian dysfunction in polycystic ovary syndrome
10.1016/j.metabol.2025.156238 · 2025 · External reference
10.1002/alz.71307
10.1002/alz.71307 · External reference
Carbamazepine transmits immune effect by activation of gut-liver axis and TLR signaling pathway from parental zebrafish to offspring
10.1093/toxsci/kfae026 · 2024 · External reference
Uncovering the impact of alcohol on internal organs and reproductive health: exploring TLR4/NF-κB and CYP2E1/ROS/Nrf2 pathways
10.1002/ame2.12436 · 2024 · External reference
Effect of Zaogong Erteng decoction on endometritis and TLR4-mediated signaling pathways
2025 · External reference
Expression of the toll-like receptor 4/myeloid differentiation factor/nuclear factor-κB pathway in placentas from women with preterm premature rupture of membranes and its clinical significance
2023 · External reference
Placental inflammation in preterm premature rupture of membranes and risk of neurodevelopmental disorders
10.3390/cells14130965 · 2025 · External reference
Phoenixin-14 alters transcriptome and steroid profiles in female green-spotted puffer (Dichotomyctere nigroviridis)
10.1038/s41598-022-13695-z · 2022 · External reference
The influence and mechanism of gut microbiota on spermatogenesis
10.1007/s10565-026-10168-1 · 2026 · External reference
Toxic effects of chronic exposure to BPAF and perturbation of gut microbiota homeostasis in marine medaka (Oryzias melastigma)
10.1016/j.scitotenv.2024.177745 · 2024 · External reference
Intestinal epithelial TLR4 knock out induces sex-specific effects on gut barrier and microbiome in an activity-based anorexia model
10.1080/19490976.2026.2637316 · 2026 · External reference
Estrone, the major postmenopausal estrogen, binds ERa to induce SNAI2, epithelial-to-mesenchymal transition, and ER+ breast cancer metastasis
10.1016/j.celrep.2022.111672 · 2022 · External reference
GnRH pulse frequency and irregularity play a role in male aging
10.1038/s43587-021-00116-5 · 2021 · External reference
Adolescent exposure to polystyrene nanoplastics induces male reproductive damage via the microbiome-gut-testis axis
10.1186/s12951-026-04069-y · 2026 · External reference
Microglia at the blood brain barrier in health and disease
10.3389/fncel.2024.1360195 · 2024 · External reference
Microglia drive diurnal variation in susceptibility to inflammatory blood-brain barrier breakdown
10.1172/jci.insight.180081 · 2024 · External reference
Endothelial tPA-dependent recruitment of microglia to vessels protects the blood-brain barrier after stroke
10.1186/s12987-026-00801-w · 2026 · External reference
Angiotensin-(1-7) antagonizes cerebral ischemia-reperfusion injury in rats via the TLR4/NF-κB signaling pathway
2018 · External reference
N-acetyldopamine dimer inhibits neuroinflammation through the TLR4/NF-κB and NLRP3/Caspase-1 pathways
2022 · External reference
Mechanism of toll-like receptor 4 signaling pathway in inflammatory responses of microglia and astrocytes following brain injury
2018 · External reference
Human placental extract negatively regulates LPS-induced inflammatory response in microglia via the TLR4/NF-κB signaling pathway
2025 · External reference
Pedunculoside attenuates the progression of neuropathic pain by affecting microglial polarization through inhibition of the TLR4-NF-κB pathway
10.1007/s10616-026-00894-z · 2026 · External reference
Microglia contributes to BAF-312 effects on blood-brain barrier stability
10.3390/biom12091174 · 2022 · External reference
Low-molecular-weight heparin protects PC12 cells against oxygen-glucose deprivation-induced inflammatory response via the TLR4/MyD88/NF-κB pathway
2021 · External reference
10.3389/fphar.2024.1443552
10.3389/fphar.2024.1443552 · External reference
The mechanism of Notopterol alleviating LPS-induced endometritis by inhibiting the TLR4/NF-κB Signaling pathway
2025 · External reference
Allicin alleviated LPS-induced mastitis via the TLR4/NF-κB Signaling pathway in bovine mammary epithelial cells
10.3390/ijms24043805 · 2023 · External reference
Inhibition of the TLR4/NF-κB pathway promotes the polarization of LPS-induced BV2 microglia toward the M2 phenotype
10.1097/wnr.0000000000001961 · 2023 · External reference
Oxysterol Signaling within the microbiome-regulated gut-liver-brain Axis: implications for metabolic homeostasis and neurodegeneration
10.1002/cph4.70181 · 2026 · External reference
Syk-MyD88 Axis is a critical determinant of inflammatory-response in activated macrophages
10.3389/fimmu.2021.767366 · 2021 · External reference
Sleep deprivation impairs follicular development attributable to granulosa cell pyroptosis mediated by S100A8/A9-driven macrophage M1 polarization
10.1126/sciadv.ady4767 · 2026 · External reference
LncRNA MEG3 restrained the M1 polarization of microglia in acute spinal cord injury through the HuR/A20/NF-κB axis
10.1111/bpa.13070 · 2022 · External reference
Danshensu methyl ester attenuated LPS-induced acute lung injury by inhibiting TLR4/NF-κB pathway
10.1016/j.resp.2024.104219 · 2024 · External reference
Multiorgan crosstalk in MASLD/MASH: from hepatic pathogenesis to systemic complications
10.3389/fendo.2025.1720780 · 2025 · External reference
SCM-198 ameliorates endometrial inflammation via suppressing the LPS-JNK-cJUN/cFOS-TLR4-NF-κB pathway
10.1093/abbs/gmab095 · 2021 · External reference
The role of endoplasmic reticulum stress in BPS-induced disruption of endometrial decidualization
10.1016/j.ecoenv.2025.118737 · 2025 · External reference
A novel adverse outcome pathway in aluminum-induced male infertility: oxidative stress-mediated endoplasmic reticulum stress and endocannabinoid system activation delineated by network toxicology and metabolomics
10.1016/j.ecoenv.2026.120060 · 2026 · External reference
10.1155/2020/1241894
10.1155/2020/1241894 · External reference
The role of systemic inflammation in hepatic encephalopathy: advances in inflammatory mechanisms, prevention and treatment research
2026 · External reference
Diabetic retinopathy and Alzheimer’s disease: convergence of the unfolded protein response in neurodegeneration
10.1002/alz.70497 · 2025 · External reference
Exploring microglia and their phenomenal concatenation of stress responses in neurodegenerative disorders
10.1016/j.lfs.2023.121920 · 2023 · External reference
The hidden hand of endoplasmic reticulum stress in anticancer drug resistance
10.1016/j.critrevonc.2025.104998 · 2026 · External reference
Jing an decoction alleviates neuroinflammation in Tourette syndrome by regulating butyrate-mediated microbiota-gut-brain axis
10.1016/j.phymed.2025.157009 · 2025 · External reference
Diabetes and its cardiovascular complications: potential role of the acetyltransferase p300
10.3390/cells12030431 · 2023 · External reference
Molecular mimicry of NF-κB by vaccinia virus protein enables selective inhibition of antiviral responses
10.1038/s41564-021-01004-9 · 2022 · External reference
LncRNA SNHG15 modulates ischemia-reperfusion injury in human AC16 cardiomyocytes depending on the regulation of the miR-335-3p/TLR4/NF-κB pathway
10.1536/ihj.21-511 · 2022 · External reference
Current and future pharmacological therapies for NAFLD/NASH
10.1007/s00535-017-1415-1 · 2018 · External reference
Gut microbiota and the liver
2017 · External reference
Intestinal permeability is a mechanical rheostat in the pathogenesis of liver cirrhosis
10.3390/ijms22136921 · 2021 · External reference
Blood endotoxin levels as biomarker of nonalcoholic fatty liver disease: a systematic review and Meta-analysis
10.1016/j.cgh.2022.11.030 · 2023 · External reference
Mining gut microbiota from bariatric surgery for MAFLD
2021 · External reference
NIK/MAP3K14 in hepatocytes orchestrates NASH to hepatocellular carcinoma progression via JAK2/STAT5 inhibition
10.1016/j.molmet.2022.101626 · 2022 · External reference
Serum amyloid A1 exacerbates hepatic steatosis via TLR4-mediated NF-κB signaling pathway
10.1016/j.molmet.2022.101462 · 2022 · External reference
The hepatocyte IKK:NF-κB axis promotes liver steatosis by stimulating de novo lipogenesis and cholesterol synthesis
10.1016/j.molmet.2021.101349 · 2021 · External reference
LPS-TLR4/MD-2-TNF-α signaling mediates alcohol-induced liver fibrosis in rats
10.1293/tox.2021-0018 · 2022 · External reference
Hepatocyte TLR4 triggers inter-hepatocyte Jagged1/notch signaling to determine NASH-induced fibrosis
10.1126/scitranslmed.abe1692 · 2021 · External reference
MAFLD enhances clinical practice for liver disease in the Asia-Pacific region
10.3350/cmh.2021.0310 · 2022 · External reference
MAFLD and NAFLD in the prediction of incident chronic kidney disease
10.1038/s41598-023-27762-6 · 2023 · External reference
A new definition for metabolic dysfunction-associated fatty liver disease: an international expert consensus statement
10.1016/j.jhep.2020.03.039 · 2020 · External reference
The gut-liver axis: microbial mechanisms and therapeutic implications in MAFLD
10.3389/fcimb.2026.1740163 · 2026 · External reference
Gypenosides counteract hepatic steatosis and intestinal barrier injury in rats with metabolic associated fatty liver disease by modulating the adenosine monophosphate activated protein kinase and toll-like receptor 4/nuclear factor kappa B pathways
10.1080/13880209.2022.2126503 · 2022 · External reference
Role of metabolic endotoxemia in systemic inflammation and potential interventions
2020 · External reference
Prevotella-derived butyrate inhibits CD8(+) T-cell glycolysis via AKT/mTOR signalling to alleviate MASH
10.1111/liv.70613 · 2026 · External reference
Ethanol extracts of Isochrysis zhanjiangensis alleviate acute alcoholic liver injury and modulate intestinal bacteria dysbiosis in mice
10.1002/jsfa.13321 · 2024 · External reference
Poria cocos polysaccharide prevents alcohol-induced hepatic injury and inflammation by repressing oxidative stress and gut leakiness
10.3389/fnut.2022.963598 · 2022 · External reference
Theaflavin-3,3′-digallate prevents alcoholic liver injury by suppressing hepatic TLR4/NF-κB signaling and modulating the gut-liver axis in mice
10.1016/j.jnutbio.2025.110031 · 2025 · External reference
Alcohol-induced oxidative stress and gut-liver-brain crosstalk: expanding the paradigm from ALD to MetALD
2025 · External reference
Investigating the expression of CD180, LY96, VCAM-1, and CSF2RB in the lipopolysaccharide response pathway across different liver cirrhosis etiologies
10.1007/s11033-025-10780-0 · 2025 · External reference
Ethanol induces neuroinflammation in a chronic plus binge mouse model of alcohol use disorder via TLR4 and MyD88-dependent Signaling
2023 · External reference
miRNA-ome plasma analysis unveils changes in blood-brain barrier integrity associated with acute liver failure in rats
10.1186/s12987-023-00484-7 · 2023 · External reference
Swertia chirayita ameliorates MAFLD by improving intestinal microenvironment and hepatic lipogenesis
10.1016/j.jep.2026.121471 · 2026 · External reference
Restoration of ethanol-induced bifidobacterium pseudocatenulatum depletion ameliorates alcohol-associated liver disease
10.1038/s41522-026-00913-z · 2026 · External reference
Reproductive function in men affected by X-linked adrenoleukodystrophy/adrenomyeloneuropathy
10.1530/eje-11-0490 · 2012 · External reference
Gut microbiome-brain-cirrhosis axis
10.1097/hep.0000000000000344 · 2024 · External reference
Inhibition of IRAK4 by microbial trimethylamine blunts metabolic inflammation and ameliorates glycemic control
10.1038/s42255-025-01413-8 · 2025 · External reference
Phillygenin inhibits neuroinflammation and promotes functional recovery after spinal cord injury via TLR4 inhibition of the NF-κB signaling pathway
10.1016/j.jot.2024.07.013 · 2024 · External reference
Rhodomyrtus tomentosa fruit ameliorates LPS induced depression-like behaviors in mice by attenuating hippocampal neuroinflammation via inhibiting the TLR4/MyD88/MAPK/NF-κB/NLRP3 signaling pathway
2026 · External reference
Therapeutic applications of resveratrol in hepatic encephalopathy through its regulation of the microbiota, brain Edema, and inflammation
2021 · External reference
Flavonoids and polycystic ovary syndrome
10.1039/d5fo04823k · 2026 · External reference
Multi-omics elucidation of Lactiplantibacillus plantarum NKK20 in preventing PCOS via the gut-ovary axis: SCFAs-mediated microbiota-metabolite-immune crosstalk
2025 · External reference
A meta-analysis-based adverse outcome pathway for the male reproductive toxicity induced by microplastics and nanoplastics in mammals
10.1016/j.jhazmat.2023.133375 · 2024 · External reference
HSYA ameliorates venous thromboembolism by depleting the formation of TLR4/NF-κB pathway-dependent neutrophil extracellular traps
10.1016/j.intimp.2024.113534 · 2024 · External reference
Dendrobium officinale polysaccharide protected CCl4-induced liver fibrosis through intestinal homeostasis and the LPS-TLR4-NF-κB signaling pathway
2020 · External reference
Polysaccharides from Eucommia ulmoides Oliv. leaves could alleviate gut microbiota dysbiosis and mitigate chronic alcoholic intoxication in mice
10.1002/mnfr.70497 · 2026 · External reference
Dihydromyricetin alleviates non-alcoholic fatty liver disease by modulating gut microbiota and inflammatory Signaling pathways
10.4014/jmb.2406.06048 · 2024 · External reference
Dietary glycerol monolaurate effect on growth performance, intestinal barrier function, and gut microbiota in weaned piglets challenged by lipopolysaccharide
2025 · External reference
Anti-PD-L1 improves barrier function and reduces CD103(+) DC cell accumulation by regulating gut and lung microbiota and its metabolites to alleviate asthma in juvenile mice
2025 · External reference
Gut microbiota regulates acute myeloid leukaemia via alteration of intestinal barrier function mediated by butyrate
10.1038/s41467-022-30240-8 · 2022 · External reference
Unresolved reference
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Dietary silymarin improves gut-liver health by enhancing intestinal barrier integrity and modulating TLR4/NF-κB and NLRP3-mediated inflammatory responses in Aeromonas hydrophila-infected grass carp
10.1016/j.fsi.2026.111135 · 2026 · External reference
Panax notoginseng saponins ameliorate high-fat diet-induced liver injury via mechanisms involving TLR4-mediated signaling and lipid metabolism
2026 · External reference
Neoastilbin ameliorates sepsis-induced liver and kidney injury by blocking the TLR4/NF-κB pathway
2024 · External reference
Eupatilin protects against isotretinoin induced hepatotoxicity through immunomodulation of TLR4/MyD88/TRAF6 and NF-κB/NrF2 pathways
10.1016/j.ejphar.2025.177920 · 2025 · External reference
Laminaria japonica fucoidan ameliorates cyclophosphamide-induced liver and kidney injury possibly by regulating Nrf2/HO-1 and TLR4/NF-κB signaling pathways
10.1002/jsfa.11602 · 2022 · External reference
Oudemansiella radicata polysaccharides alleviated LPS-induced liver damage via regulating TLR4/NF-κB and Bax/Bcl-2 signaling pathways
10.1016/j.ijbiomac.2024.137370 · 2024 · External reference
Asiatic acid alleviates LPS-induced Pyroptosis and endoplasmic reticulum stress-mediated apoptosis via inhibiting the HMGB1/TLR4/NF-κB pathway in broiler hepatocytes
10.1111/jpn.14070 · 2025 · External reference
Fatty liver disease - non alcoholic to metabolic - a transition of concepts!!
10.4103/jfmpc.jfmpc_1863_21 · 2024 · External reference
Macrophage polarization and its role in liver disease
10.3389/fimmu.2021.803037 · 2021 · External reference
Pasteurella multocida causes liver injury in ducks by mediating inflammatory, apoptotic and autophagic pathways
10.1016/j.micpath.2023.106336 · 2023 · External reference
Preventive and therapeutic role of betaine in liver disease: a review on molecular mechanisms
10.1016/j.ejphar.2021.174604 · 2021 · External reference
Natural polysaccharides as potential anti-fibrotic agents: a review of their progress
10.1016/j.lfs.2022.120953 · 2022 · External reference
Role of the gut microbiota in nutrition and health
2018 · External reference
Controversies in clinical trials for alcoholic hepatitis
10.1016/j.jhep.2017.09.013 · 2018 · External reference
Therapeutic potential of phages in autoimmune liver diseases
10.1111/cei.13092 · 2018 · External reference
Molecular and regenerative effects of platelet-rich plasma and related Hemocomponents in animal models of liver injury-a systematic review
10.3390/ijms27021013 · 2026 · External reference
Beyond organ boundaries: molecular mechanisms of hepatic encephalopathy and Parkinson’s disease from the perspective of the gut-liver-brain axis
2026 · External reference
Plant-derived polyphenolic compounds: nanodelivery through polysaccharide-based systems to improve the biological properties
10.1080/10408398.2023.2245038 · 2024 · External reference
Enhancing oral bioavailability and immunostimulatory activity of Glycyrrhiza uralensis polysaccharides through PLGA nanoparticle delivery system
10.1016/j.ijbiomac.2026.152254 · 2026 · External reference
Therapeutic potential of genistein: preclinical studies, clinical evidence, and nanotechnology application
10.2174/0929867329666221004124800 · 2023 · External reference
Uptake and transport mechanism of dihydromyricetin across human intestinal Caco-2 cells
10.1111/1750-3841.14112 · 2018 · External reference
Dihydromyricetin: a review on identification and quantification methods, biological activities, chemical stability, metabolism and approaches to enhance its bioavailability
10.1016/j.tifs.2019.07.038 · 2019 · External reference
Multi-target pharmacological effects of Asiatic acid: advances in structural modification and novel drug delivery systems
10.3390/molecules30183688 · 2025 · External reference
Effect of ginseng saponins on beta-amyloid-suppressed acetylcholine release from rat hippocampal slices
10.1055/s-2001-17366 · 2001 · External reference
Starring role of toll-like receptor-4 activation in the gut-liver axis
10.4291/wjgp.v6.i4.99 · 2015 · External reference
S100A8/A9 in recurrent pregnancy loss: pathogenic mechanisms and therapeutic potential
10.1016/j.jri.2026.104938 · 2026 · External reference
NF-κB/IL-6 axis drives impaired corneal wound healing in aqueous-deficient dry eye
10.3389/fimmu.2025.1684290 · 2025 · External reference
Enalaprilat reverses neutrophil polarization imbalance via targeting taurine-STING axis for treatment of diabetic wounds
2026 · External reference
Immunomodulatory and immunoregulatory nanomedicines for autoimmunity
10.1016/j.smim.2021.101535 · 2021 · External reference
