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References from A H2S-releasing oridonin derivative improves diabetic wound healing based on antibacterial activity and regulation of macrophage phagocytosis. Local targets link to admitted publications; unresolved targets remain external evidence.
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10.1056/nejmra1615439 · 2017 · External reference
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10.3389/fimmu.2021.648554 · 2021 · External reference
A multiomics approach to identify host-microbe alterations associated with infection severity in diabetic foot infections: a pilot study
10.1038/s41522-021-00202-x · 2021 · External reference
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2007 · External reference
The insights of microbes’ roles in wound healing: a comprehensive review
10.3390/pharmaceutics13070981 · 2021 · External reference
Skin wound healing: Normal macrophage function and macrophage dysfunction in diabetic wounds
10.3390/molecules26164917 · 2021 · External reference
The innate immune system, toll-like receptors and dermal wound healing: a review
10.1016/j.vph.2015.02.007 · 2015 · External reference
Human microflora, probiotics and wound healing
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Intracellular glutathione depletion by Oridonin leads to apoptosis in hepatic stellate cells
10.3390/molecules19033327 · 2014 · External reference
Molecular insight in the multifunctional effects of Oridonin
10.1007/s40268-015-0102-z · 2015 · External reference
Oridonin: a review of its pharmacology, pharmacokinetics and toxicity
10.3389/fphar.2021.645824 · 2021 · External reference
Activation of phosphoinositide 3-kinase, protein kinase C, and extracellular signal-regulated kinase is required for Oridonin-enhanced phagocytosis of apoptotic bodies in human macrophage-like U937 cells
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Roles of Ras and extracellular signal-regulated kinase-dependent IκBα degradation in oridonin-enhanced phagocytosis of apoptotic cells by human macrophage-like U937 cells
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Autophagy enhanced phagocytosis of apoptotic cells by oridonin-treated human histocytic lymphoma U937 cells
10.1016/j.abb.2011.11.019 · 2012 · External reference
Novel nitrogen-enriched Oridonin analogues with thiazole-fused A-ring: protecting group-free synthesis, enhanced anticancer profile, and improved aqueous solubility
10.1021/jm400367n · 2013 · External reference
Hydrogen sulfide plays an important protective role by influencing autophagy in diseases
2019 · External reference
Exogenous hydrogen sulfide plays an important role by regulating autophagy in diabetic-related diseases
10.3390/ijms22136715 · 2021 · External reference
Synthesis, metabolism, and signaling mechanisms of hydrogen sulfide: An overview
2019 · External reference
Potential role of hydrogen sulfide in diabetes-impaired angiogenesis and ischemic tissue repair
10.1016/j.redox.2020.101704 · 2020 · External reference
Role of hydrogen sulfide in chronic diseases
10.1089/dna.2019.5067 · 2020 · External reference
Vascular smooth muscle cell-derived hydrogen sulfide promotes atherosclerotic plaque stability via TFEB (transcription factor EB)-mediated autophagy
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Autophagy in Staphylococcus aureus infection
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Polymersome wound dressing spray capable of bacterial inhibition and H2S generation for complete diabetic wound healing
10.1021/acs.chemmater.1c01872 · 2021 · External reference
Hydrogen sulfide inhibits the growth of Escherichia coli through oxidative damage
10.1007/s12275-018-7537-1 · 2018 · External reference
Mechanism of H2S-mediated protection against oxidative stress in Escherichia coli
10.1073/pnas.1703576114 · 2017 · External reference
H2S-releasing oridonin derivatives with improved antitumor activity by inhibiting the PI3K/AKT pathway
10.1016/j.bmc.2024.117968 · 2024 · External reference
Hydrogen sulfide releasing oridonin derivatives induce apoptosis through extrinsic and intrinsic pathways
10.1016/j.ejmech.2019.111978 · 2020 · External reference
Hydrogen sulfide donating ent-kaurane and spirolactone-type 6,7-seco-ent-kaurane derivatives: design, synthesis and antiproliferative properties
10.1016/j.ejmech.2019.06.016 · 2019 · External reference
A comparison of techniques for collecting skin microbiome samples: swabbing versus tape-stripping
10.3389/fmicb.2018.02362 · 2018 · External reference
Heterogeneous parallelization and acceleration of molecular dynamics simulations in
2020 · External reference
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1996 · External reference
Toll-like receptors activation, signaling, and targeting: an overview
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Autophagy and macrophage functions: inflammatory response and phagocytosis
10.3390/cells9010070 · 2019 · External reference
Unresolved reference
External reference
Current understanding of molecular and cellular mechanisms in fibroplasia and angiogenesis during acute wound healing
10.1016/j.jdermsci.2013.07.008 · 2013 · External reference
Expression of antimicrobial peptides in diabetic foot ulcer
10.1016/j.jdermsci.2011.09.013 · 2012 · External reference
A versatile Glycopeptide hydrogel promotes chronic refractory wound healing through bacterial elimination, sustained oxygenation, Immunoregulation, and neovascularization
10.1002/adfm.202305992 · 2023 · External reference
Colonizing microbiota is associated with clinical outcomes in diabetic wound healing
10.1016/j.addr.2023.114727 · 2023 · External reference
Targeted macrophage phagocytosis by Irg1/itaconate axis improves the prognosis of intracerebral hemorrhagic stroke and peritonitis
10.1016/j.ebiom.2024.104993 · 2024 · External reference
TLR2 mediates phagocytosis and autophagy through JNK signaling pathway in Staphylococcus aureus-stimulated RAW264.7 cells
10.1016/j.cellsig.2013.12.016 · 2014 · External reference
Cellular autophagy: surrender, avoidance and subversion by microorganisms
10.1038/nrmicro865 · 2004 · External reference
Interactions of autophagy and the immune system in health and diseases
2022 · External reference
Crosstalk between autophagy and inflammatory signalling pathways: balancing defence and homeostasis
10.1038/nri.2016.100 · 2016 · External reference
ATG16L1 negatively regulates RICK/RIP2-mediated innate immune responses
10.1093/intimm/dxaa062 · 2021 · External reference
Crosstalk between NOD2 and TLR2 suppresses the development of TLR2-mediated experimental colitis
2023 · External reference
Selective autophagy of the adaptor TRIF regulates innate inflammatory signaling
10.1038/s41590-017-0042-6 · 2018 · External reference
Phospholipid peroxidation in macrophage confers tumor resistance by suppressing phagocytic capability towards ferroptotic cells
10.1038/s41418-024-01351-0 · 2024 · External reference
TRIM58 restrains intestinal mucosal inflammation by negatively regulating TLR2 in myeloid cells
10.4049/jimmunol.1900413 · 2019 · External reference
RING finger E3 ligase PPP1R11 regulates TLR2 signaling and innate immunity
10.7554/elife.18496 · 2016 · External reference
Phytochemical nanozymes reprogram redox for balanced antimicrobial and regenerative therapy in acute and chronic diabetic wounds
10.1016/j.redox.2025.103718 · 2025 · External reference
10.1016/j.mtbio.2025.102269
10.1016/j.mtbio.2025.102269 · External reference