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References from Levocarnitine attenuates diabetic seminal vesicle fibrosis in association with improved lipid metabolism and reduced ER stress. Local targets link to admitted publications; unresolved targets remain external evidence.
Emerging Targets in Type 2 Diabetes and Diabetic Complications
10.1002/advs.202100275 · 2021 · External reference
More Adolescents and Young Adults Developing Type 2 Diabetes Around the World
2023 · External reference
Diabetes-induced hyperglycemia impairs male reproductive function: a systematic review
10.1093/humupd/dmx033 · 2018 · External reference
Morphology and functions of the human seminal vesicle
10.1111/j.1439-0272.1992.tb02636.x · 1992 · External reference
Lysyl oxidase promotes seminal vesicle atrophy and fibrosis in type-2 diabetes mellitus through TGF-β1 signaling
10.1186/s12967-025-06590-4 · 2025 · External reference
Ultrasound characterization of the seminal vesicles in infertile patients with type 2 diabetes mellitus
10.1016/j.ejrad.2010.08.001 · 2011 · External reference
Diabetes-induced male infertility: potential mechanisms and treatment options
10.1186/s10020-023-00771-x · 2024 · External reference
Combined resveratrol and vitamin D treatment ameliorate inflammation-related liver fibrosis, ER stress, and apoptosis in a high-fructose diet/streptozotocin-induced T2DM model
10.1007/s00418-022-02131-y · 2022 · External reference
Advanced glycation end products induce skeletal muscle atrophy and insulin resistance via activating ROS-mediated ER stress PERK/FOXO1 signaling
10.1152/ajpendo.00218.2022 · 2023 · External reference
Endoplasmic reticulum stress and lipids in health and diseases
10.1016/j.plipres.2022.101198 · 2023 · External reference
Endoplasmic reticulum stress mechanisms and exercise intervention in type 2 diabetes mellitus
10.1016/j.biopha.2024.117122 · 2024 · External reference
Endoplasmic reticulum stress induces renal fibrosis in high-fat diet mice via the TGF-β/SMAD pathway
10.3892/mmr.2024.13360 · 2024 · External reference
Significance of l-carnitine for human health
10.1002/iub.1646 · 2017 · External reference
l-Carnitine relieves cachexia-related skeletal muscle fibrosis by inducing deltex E3 ubiquitin ligase 3L to negatively regulate the Runx2/COL1A1 axis
10.1002/jcsm.13544 · 2024 · External reference
L-carnitine treatment attenuates renal tubulointerstitial fibrosis induced by unilateral ureteral obstruction
10.3904/kjim.2019.413 · 2021 · External reference
Involvement of impaired carnitine-induced fatty acid oxidation in experimental and human diabetic kidney disease
10.1172/jci.insight.179362 · 2025 · External reference
The Importance of the Fatty Acid Transporter L-Carnitine in Non-Alcoholic Fatty Liver Disease (NAFLD)
10.3390/nu12082178 · 2020 · External reference
L-Carnitine and Male Fertility: Is Supplementation Beneficial
10.3390/jcm12185796 · 2023 · External reference
l-carnitine and l-acetylcarnitine supplementation for idiopathic male infertility
10.1530/raf-20-0037 · 2020 · External reference
Molecular insights into Sertoli cell function: how do metabolic disorders in childhood and adolescence affect spermatogonial fate
10.1038/s41467-024-49765-1 · 2024 · External reference
Curcumin ameliorates pyroptosis in diabetic seminal vesicles by upregulating TRPV6
10.1111/andr.13687 · 2025 · External reference
Ultrastructure and function of the seminal vesicle of Bittacidae (Insecta: Mecoptera)
10.1016/j.asd.2018.02.001 · 2018 · External reference
Structural and ultrastructural features of boar seminal vesicles
10.1016/j.tice.2005.12.001 · 2006 · External reference
The Biochemistry and Physiology of Mitochondrial Fatty Acid β-Oxidation and Its Genetic Disorders
10.1146/annurev-physiol-021115-105045 · 2016 · External reference
Inhibition of carnitine palmitoyltransferase 1A in hepatic stellate cells protects against fibrosis
10.1016/j.jhep.2022.02.003 · 2022 · External reference
The role of ER stress in lipid metabolism and lipotoxicity
10.1194/jlr.r067595 · 2016 · External reference
The molecular basis for selective inhibition of unconventional mRNA splicing by an IRE1-binding small molecule
10.1073/pnas.1115623109 · 2012 · External reference
Dietary l-carnitine regulates liver lipid metabolism via simultaneously activating fatty acid β-oxidation and suppressing endoplasmic reticulum stress in large yellow croaker fed with high-fat diets
10.1017/s0007114522000101 · 2023 · External reference
L-carnitine protects cardiac damage by reducing oxidative stress and inflammatory response via inhibition of tumor necrosis factor-alpha and interleukin-1beta against isoproterenol-induced myocardial infarction
10.1016/j.biopha.2021.112139 · 2021 · External reference
Obestatin and L-carnitine as a defensive strategy against fertility disorders induced by obesity in male rats
10.4103/1110-1415.143565 · 2014 · External reference
Hyperglycemia and Oxidative Stress: An Integral, Updated and Critical Overview of Their Metabolic Interconnections
10.3390/ijms24119352 · 2023 · External reference
Advanced Glycation End Products and Diabetes Mellitus: Mechanisms and Perspectives
10.3390/biom12040542 · 2022 · External reference
Testosterone-induced metabolic changes in seminal vesicle epithelium modify seminal plasma components with potential to improve sperm motility
10.7554/elife.95541.5 · 2025 · External reference
Macrophage transition to a myofibroblast state drives fibrotic disease in uropathogenic E. coli-induced epididymo-orchitis
10.1172/jci193793 · 2025 · External reference
AGER1 deficiency-triggered ferroptosis drives fibrosis progression in nonalcoholic steatohepatitis with type 2 diabetes mellitus
10.1038/s41420-023-01477-z · 2023 · External reference
Exploring Liraglutide's mechanism in reducing renal fibrosis: the Fsp1-CoQ10-NAD(P)H pathway
10.1038/s41598-025-85658-z · 2025 · External reference
Recommendations for robust and reproducible research on ferroptosis
10.1038/s41580-025-00843-2 · 2025 · External reference
Pattern recognition receptor-mediated innate immune responses in seminal vesicle epithelial cell and their impacts on cellular function
10.1093/biolre/ioz136 · 2019 · External reference