Contact and support
Need help, have a question, or want to contact the ResearchHub team?
© 2026 ResearchHub. Built for responsible scholarly connection.
Privacy-aware community infrastructureResearch graph
References from A cetacean-specific CNE suppresses osteogenesis to drive appendicular modification in secondary aquatic adaptation. Local targets link to admitted publications; unresolved targets remain external evidence.
Mammalian forelimb evolution is driven by uneven proximal-to-distal morphological diversity
10.7554/elife.81492 · 2023 · External reference
The origin of vertebrate limbs
10.1242/dev.1994.supplement.169 · 1994 · External reference
Fossils, genes and the evolution of animal limbs
10.1038/41710 · 1997 · External reference
First discovery of a primitive coelacanth fin fills a major gap in the evolution of lobed fins and limbs
10.1111/j.1525-142x.2007.00169.x · 2007 · External reference
The pectoral fin of Tiktaalik roseae and the origin of the tetrapod limb
10.1038/nature04637 · 2006 · External reference
Limbs in whales and limblessness in other vertebrates: mechanisms of evolutionary and developmental transformation and loss
10.1046/j.1525-142x.2002.02033.x · 2002 · External reference
Evolution of hyperphalangy and digit reduction in the cetacean manus
10.1002/ar.20532 · 2007 · External reference
Developmental basis for hind-limb loss in dolphins and origin of the cetacean bodyplan
10.1073/pnas.0602920103 · 2006 · External reference
Adaptive evolution of BMP4 as a potential mechanism for flipper forelimb changes in cetaceans
10.24272/j.issn.2095-8137.2024.473 · 2025 · External reference
Relaxed selection in evolution of genes regulating limb development gives clue to variation in forelimb morphology of cetaceans and other mammals
2024 · External reference
Adaptive evolution of 5'HoxD genes in the origin and diversification of the cetacean flipper
10.1093/molbev/msn282 · 2009 · External reference
Cis-regulatory programs in the development and evolution of vertebrate paired appendages
10.1016/j.semcdb.2016.01.015 · 2016 · External reference
Research progresses on non-coding DNA regulatory elements in the evolution of animal adaptive traits
2024 · External reference
Conserved non-coding elements: developmental gene regulation meets genome organization
10.1093/nar/gkx1074 · 2017 · External reference
Evolutionary Innovations in Conserved Regulatory Elements Associate With Developmental Genes in Mammals
10.1093/molbev/msae199 · 2024 · External reference
Convergent and lineage-specific genomic differences in limb regulatory elements in limbless reptile lineages
10.1016/j.celrep.2021.110280 · 2022 · External reference
Conserved noncoding cis elements associated with hibernation modulate metabolic and behavioral adaptations in mice
10.1126/science.adp4701 · 2025 · External reference
Strategic planning of prevention and surveillance for emerging diseases and invasive species
2025 · External reference
Functional evidence supports the potential role of Tbx4-HLEA in the hindlimb degeneration of cetaceans
10.1186/s13227-025-00239-5 · 2025 · External reference
Evolution of cetacean-specific conserved non-coding elements suggests their role in the limb changes during secondary aquatic adaptation
10.1186/s12915-025-02300-0 · 2025 · External reference
Multi-level genomic convergence of secondary aquatic adaptation in marine mammals
2025 · External reference
Return to the Sea: The Evolution of Marine Mammals
2019 · External reference
Convergent Degenerated Regulatory Elements Associated with Limb Loss in Limbless Amphibians and Reptiles
10.1093/molbev/msae239 · 2024 · External reference
Sink or swim? Bone density as a mechanism for buoyancy control in early cetaceans
10.1002/ar.20533 · 2007 · External reference
Microstructural differences in the osteochondral unit of terrestrial and aquatic mammals
10.7554/elife.80936 · 2023 · External reference
Linking gene expression and phenotypic changes in the developmental and evolutionary origins of osteosclerosis in the ribs of bowhead whales (Balaena mysticetus)
10.1002/jez.b.22990 · 2020 · External reference
Review and experimental evaluation of the embryonic development and evolutionary history of flipper development and hyperphalangy in dolphins (Cetacea: Mammalia)
10.1002/dvg.23076 · 2018 · External reference
Developmental and Evolutionary Allometry of the Mammalian Limb Skeleton
10.1093/icb/icz082 · 2019 · External reference
Enlightenment of Growth Plate Regeneration Based on Cartilage Repair Theory: A Review
2021 · External reference
Bone-derived factors mediate crosstalk between skeletal and extra-skeletal organs
10.1038/s41413-025-00424-1 · 2025 · External reference
Transition of Eocene Whales from Land to Sea: Evidence from Bone Microstructure
10.1371/journal.pone.0118409 · 2015 · External reference
Evo-devo and an expanding evolutionary synthesis: a genetic theory of morphological evolution
10.1016/j.cell.2008.06.030 · 2008 · External reference
Timing the developmental origins of mammalian limb diversity
10.1002/dvg.23079 · 2018 · External reference
Graph-based genome alignment and genotyping with HISAT2 and HISAT-genotype
10.1038/s41587-019-0201-4 · 2019 · External reference
Moderated estimation of fold change and dispersion for RNA-seq data with DESeq2
10.1186/s13059-014-0550-8 · 2014 · External reference
clusterProfiler 4.0: A universal enrichment tool for interpreting omics data
2021 · External reference
3 - A Revised Staging of Mouse Development Before Organogenesis
2016 · External reference
An automated technique for double staining of bone and cartilage in fetal mouse skeletal specimens using alizarin red S and Alcian blue
10.1080/10520295.2021.1933179 · 2022 · External reference
Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method
10.1006/meth.2001.1262 · 2001 · External reference
