Research graph
References from Amphiregulin shapes mitochondrial delivery and immune modulation by microvescicles. Local targets link to admitted publications; unresolved targets remain external evidence.
Fibrosis: from mechanisms to medicines
10.1038/s41586-020-2938-9 · 2020 · External reference
The Long Path of Human Placenta, and Its Derivatives, in Regenerative Medicine
10.3389/fbioe.2015.00162 · 2015 · External reference
Type 2 immunity in tissue repair and fibrosis
10.1038/nri.2017.90 · 2018 · External reference
Regenerative inflammation: When immune cells help to re-build tissues
10.1111/febs.16693 · 2024 · External reference
Inflammation and its Role in Regeneration and Repair
10.1161/circresaha.118.314669 · 2019 · External reference
Tendon Immune Regeneration: Insights on the Synergetic Role of Stem and Immune Cells during Tendon Regeneration
10.3390/cells11030434 · 2022 · External reference
Immunomodulation for Tissue Repair and Regeneration
10.1007/s13770-023-00525-0 · 2023 · External reference
Immunomodulation—a general review of the current state-of-the-art and new therapeutic strategies for targeting the immune system
10.3389/fimmu.2023.1127704 · 2023 · External reference
Unresolved reference
External reference
Application of human amniotic epithelial cells in regenerative medicine: a systematic review
10.1186/s13287-020-01951-w · 2020 · External reference
Gestational stage affects amniotic epithelial cells phenotype, methylation status, immunomodulatory and stemness properties
10.1007/s12015-014-9519-y · 2014 · External reference
Therapeutic potential of hAECs for early Achilles tendon defect repair through regeneration
10.1002/term.2584 · 2018 · External reference
Tendon Healing Response Is Dependent on Epithelial-Mesenchymal-Tendon Transition State of Amniotic Epithelial Stem Cells
10.3390/biomedicines10051177 · 2022 · External reference
Achilles tendon regeneration can be improved by amniotic epithelial cell allotransplantation
10.3727/096368912x638892 · 2012 · External reference
Amniotic epithelial Cell microvesicles uptake inhibits PBMCs and Jurkat cells activation by inducing mitochondria-dependent apoptosis
10.1016/j.isci.2025.111830 · 2025 · External reference
Amphiregulin Orchestrates the Paracrine Immune-Suppressive Function of Amniotic-Derived Cells Through its Interplay with COX-2/PGE2/EP4 Axis
10.1016/j.isci.2024.110508 · 2024 · External reference
In Vitro Innovation of Tendon Tissue Engineering Strategies
10.3390/ijms21186726 · 2020 · External reference
Development of Amniotic Epithelial Stem Cells Secretome-Loaded In Situ Inverse Electron Demand Diels–Alder-Cross-Linked Hydrogel as a Potential Immunomodulatory Therapeutical Tool
10.1021/acsami.4c16659 · 2025 · External reference
Immunosuppressive factors secreted by human amniotic epithelial cells
10.1167/iovs.04-0495 · 2005 · External reference
Bone marrow-derived hematopoietic cells generate cardiomyocytes at a low frequency through cell fusion, but not transdifferentiation
10.1038/nm1040 · 2004 · External reference
Bone marrow cells adopt the phenotype of other cells by spontaneous cell fusion
10.1038/nature730 · 2002 · External reference
Graphene oxide accelerates TGFβ-mediated epithelial-mesenchymal transition and stimulates pro-inflammatory immune response in amniotic epithelial cells
2023 · External reference
Unveiling the immunomodulatory shift: Epithelial-mesenchymal transition Alters immune mechanisms of amniotic epithelial cells
10.1016/j.isci.2023.107582 · 2023 · External reference
Characterization of the Conditioned Medium from Amniotic Membrane Cells: Prostaglandins as Key Effectors of Its Immunomodulatory Activity
10.1371/journal.pone.0046956 · 2012 · External reference
Human Amniotic Membrane-Derived Mesenchymal and Epithelial Cells Exert Different Effects on Monocyte-Derived Dendritic Cell Differentiation and Function
10.3727/096368914x684033 · 2015 · External reference
Amniotic mesenchymal tissue cells inhibit dendritic cell differentiation of peripheral blood and amnion resident monocytes
10.3727/096368909x471314 · 2009 · External reference
Amnion-derived multipotent progenitor cells inhibit blood monocyte differentiation into mature dendritic cells
10.3727/096368913x670165 · 2014 · External reference
Assessing the functional potential of conditioned media derived from amniotic epithelial stem cells engineered on 3D biomimetic scaffolds: An in vitro model for tendon regeneration
2024 · External reference
Amnion-Derived Teno-Inductive Secretomes: A Novel Approach to Foster Tendon Differentiation and Regeneration in an Ovine Model
10.3389/fbioe.2021.649288 · 2021 · External reference
Human Amniotic Epithelial Cells Secretome: Components, Bioactivity, and Challenges
2021 · External reference
Tendon 3D Scaffolds Establish a Tailored Microenvironment Instructing Paracrine Mediated Regenerative Amniotic Epithelial Stem Cells Potential
10.3390/biomedicines10102578 · 2022 · External reference
Hypoxia-Mimetic CoCl2 Agent Enhances Pro-Angiogenic Activities in Ovine Amniotic Epithelial Cells-Derived Conditioned Medium
10.3390/cells11030461 · 2022 · External reference
Emerging Functions of Amphiregulin in Orchestrating Immunity, Inflammation, and Tissue Repair
10.1016/j.immuni.2015.01.020 · 2015 · External reference
Innate lymphoid cells promote lung-tissue homeostasis after infection with influenza virus
10.1038/ni.2131 · 2011 · External reference
A special population of regulatory T cells potentiates muscle repair
10.1016/j.cell.2013.10.054 · 2013 · External reference
Role of tissue protection in lethal respiratory viral-bacterial coinfection
10.1126/science.1233632 · 2013 · External reference
Increased immunomodulatory capacity of human amniotic cells after activation by pro-inflammatory chemokines
10.1016/j.ejphar.2019.172545 · 2019 · External reference
Mapping of the Human Amniotic Membrane: In Situ Detection of Microvesicles Secreted by Amniotic Epithelial Cells
10.1177/09636897231166209 · 2023 · External reference
Macropinocytosis: Biology and mechanisms
10.1016/j.cdev.2021.203713 · 2021 · External reference
Amphiregulin enhances regulatory T cell-suppressive function via the epidermal growth factor receptor
10.1016/j.immuni.2012.09.023 · 2013 · External reference
Chemokine Cxcl1-Cxcl2 heterodimer is a potent neutrophil chemoattractant
10.1093/jleuko/qiad097 · 2023 · External reference
Amphiregulin Exosomes Increase Cancer Cell Invasion
10.1016/j.cub.2011.03.043 · 2011 · External reference
Selection of red fluorescent protein for genetic labeling of mitochondria and intercellular transfer of viable mitochondria
10.1038/s41598-022-24297-0 · 2022 · External reference
Influence of Intergeneric/Interspecies Mitochondrial Injection; Parthenogenetic Development of Bovine Oocytes after Injection of Mitochondria Derived from Somatic Cells
10.1262/jrd.2011-013 · 2012 · External reference
Mitochondria dysfunction in CD8+ T cells as an important contributing factor for cancer development and a potential target for cancer treatment: a review
10.1186/s13046-022-02439-6 · 2022 · External reference
NFAT control of immune function: New Frontiers for an Abiding Trooper
10.12688/f1000research.13426.1 · 2018 · External reference
The Transcription Factor NF-ATc1 Regulates Lymphocyte Proliferation and Th2 Cytokine Production
10.1016/s1074-7613(00)80464-1 · 1998 · External reference
Cell cycle and apoptosis regulation by NFAT transcription factors: new roles for an old player
10.1038/cddis.2016.97 · 2016 · External reference
Extracellular vesicles: immunomodulation, diagnosis, and promising therapeutic roles for rheumatoid arthritis
10.3389/fimmu.2024.1499929 · 2024 · External reference
The biology and function of extracellular vesicles in immune response and immunity
10.1016/j.immuni.2024.07.009 · 2024 · External reference
Human amniotic epithelial cell-derived extracellular vesicles provide an extracellular matrix-based microenvironment for corneal injury repair
10.1177/20417314221122123 · 2022 · External reference
Immersed in a reservoir of potential: amniotic fluid-derived extracellular vesicles
10.1186/s12967-024-05154-2 · 2024 · External reference
Disclosing the molecular profile of the human amniotic mesenchymal stromal cell secretome by filter-aided sample preparation proteomic characterization
10.1186/s13287-023-03557-4 · 2023 · External reference
Human amniotic fluid derived extracellular vesicles attenuate T cell immune response
10.3389/fimmu.2022.977809 · 2022 · External reference
Extracellular vesicles from neural stem cells transfer IFN-γ via Ifngr1 to activate Stat1 signaling in target cells
10.1016/j.molcel.2014.08.020 · 2014 · External reference
Platelet EVs contain an active proteasome involved in protein processing for antigen presentation via MHC-I molecules
10.1182/blood.2020009957 · 2021 · External reference
Mitochondrial transfer from mesenchymal stem cells improves neuronal metabolism after oxidant injury in vitro: The role of Miro1
10.1177/0271678x20928147 · 2021 · External reference
Immune evasion through mitochondrial transfer in the tumour microenvironment
10.1038/s41586-024-08439-0 · 2025 · External reference
The Potential Use of Mitochondrial Extracellular Vesicles as Biomarkers or Therapeutical Tools
10.3390/ijms24087005 · 2023 · External reference
Immunoregulatory Effects of Mitochondria Transferred by Extracellular Vesicles
2020 · External reference
Mitochondrial Extracellular Vesicles - Origins and Roles
10.3389/fnmol.2021.767219 · 2021 · External reference
The interconnected role of chemokines and estrogen in bone metabolism
10.5582/bst.2016.01072 · 2017 · External reference
Therapy-induced secretion of spliceosomal components mediates pro-survival crosstalk between ovarian cancer cells
10.1038/s41467-024-49512-6 · 2024 · External reference
Extracellular vesicles: a new frontier in diagnosing and treating graft-versus-host disease after allogeneic hematopoietic cell transplantation
10.1186/s12951-025-03297-y · 2025 · External reference
Extracellular Vesicles: Novel Potential Therapeutic Agents in Inflammatory Bowel Diseases
10.3390/cells13010090 · 2023 · External reference
Extracellular vesicles from mesenchymal stem cells reduce neuroinflammation in hippocampus and restore cognitive function in hyperammonemic rats
10.1186/s12974-022-02688-4 · 2023 · External reference
Extracellular vesicles in tumor immunity: mechanisms and novel insights
10.1186/s12943-025-02233-w · 2025 · External reference
The Bottlenecks in Translating Placenta-Derived Amniotic Epithelial and Mesenchymal Stromal Cells Into the Clinic: Current Discrepancies in Marker Reports
10.3389/fbioe.2020.00180 · 2020 · External reference
Multipotent mesenchymal stem cells from human placenta: critical parameters for isolation and maintenance of stemness after isolation
10.1016/j.ajog.2009.10.869 · 2010 · External reference
In Vitro Effect of Estradiol and Progesterone on Ovine Amniotic Epithelial Cells
10.1155/2019/8034578 · 2019 · External reference
Progesterone prevents epithelial-mesenchymal transition of ovine amniotic epithelial cells and enhances their immunomodulatory properties
10.1038/s41598-017-03908-1 · 2017 · External reference
Progesterone Prolongs Viability and Anti-inflammatory Functions of Explanted Preterm Ovine Amniotic Membrane
10.3389/fbioe.2020.00135 · 2020 · External reference
Progesterone Elicits an Inhibitory Effect upon LPS -Induced Innate Immune Response in Pre-Labor Human Amniotic Epithelium
10.1111/aji.12163 · 2014 · External reference
Online Parallel Accumulation-Serial Fragmentation (PASEF) with a Novel Trapped Ion Mobility Mass Spectrometer
10.1074/mcp.tir118.000900 · 2018 · External reference
diaPASEF: parallel accumulation-serial fragmentation combined with data-independent acquisition
10.1038/s41592-020-00998-0 · 2020 · External reference
DIA-NN: neural networks and interference correction enable deep proteome coverage in high throughput
10.1038/s41592-019-0638-x · 2020 · External reference
dia-PASEF data analysis using FragPipe and DIA-NN for deep proteomics of low sample amounts
10.1038/s41467-022-31492-0 · 2022 · External reference
ClueGO: a Cytoscape plug-in to decipher functionally grouped gene ontology and pathway annotation networks
10.1093/bioinformatics/btp101 · 2009 · External reference
MissForest—non-parametric missing value imputation for mixed-type data
10.1093/bioinformatics/btr597 · 2012 · External reference
SciPy 1.0: fundamental algorithms for scientific computing in Python
10.1038/s41592-019-0686-2 · 2020 · External reference
Statsmodels: Econometric and Statistical Modeling with Python
10.25080/majora-92bf1922-011 · 2010 · External reference
