Research graph
References from N-propargylputrescine as a minimal-tag probe for imaging putrescine dynamics in cellular homeostasis and stress. Local targets link to admitted publications; unresolved targets remain external evidence.
Recent advances in the biochemistry of polyamines in eukaryotes
10.1042/bj2340249 · 1986 · External reference
Spermidine in health and disease
10.1126/science.aan2788 · 2018 · External reference
Polyamines and the development of isolated neurons in cell culture
10.1007/bf00964520 · 1984 · External reference
Role of ornithine decarboxylase and the polyamines in nervous system development: a review
10.1016/0361-9230(86)90236-4 · 1986 · External reference
Polyamine-dependent facilitation of postsynaptic AMPA receptors counteracts paired-pulse depression
10.1038/44151 · 1999 · External reference
Arginase I and polyamines act downstream from cyclic AMP in overcoming inhibition of axonal growth MAG and myelin in vitro
10.1016/s0896-6273(02)00826-7 · 2002 · External reference
Polyamines increase in sympathetic neurons and non-neuronal cells after axotomy and enhance neurite outgrowth in nerve growth factor-primed PC12 cells
10.1016/j.neuroscience.2004.07.014 · 2004 · External reference
Modulation of the NMDA receptor by polyamines
10.1016/0024-3205(91)90463-l · 1991 · External reference
Endogenous polyamines regulate cortical neuronal excitability by blocking voltage-gated Na+ channels
10.1073/pnas.0803464105 · 2008 · External reference
Impaired polyamine metabolism causes behavioral and neuroanatomical defects in a mouse model of Snyder-Robinson syndrome
10.1242/dmm.050639 · 2024 · External reference
Bachmann–Bupp syndrome and treatment
10.1111/dmcn.15687 · 2024 · External reference
Implication of the polyamine system in mental disorders
10.1139/jpn.0812 · 2008 · External reference
Polyamines in Parkinson’s Disease: Balancing Between Neurotoxicity and Neuroprotection
10.1146/annurev-biochem-071322-021330 · 2023 · External reference
The Involvement of Polyamines Catabolism in the Crosstalk between Neurons and Astrocytes in Neurodegeneration
10.3390/biomedicines10071756 · 2022 · External reference
The Potential Role of Polyamines in Epilepsy and Epilepsy-Related Pathophysiological Changes
10.3390/biom12111596 · 2022 · External reference
Polyamine metabolism in epileptic cortex
10.1016/0920-1211(92)90035-r · 1992 · External reference
Acrolein is involved in ischemic stroke-induced neurotoxicity through spermidine/spermine-N1-acetyltransferase activation
10.1016/j.expneurol.2019.113066 · 2020 · External reference
The Role of Reduced Polyamine Synthesis in Ischemic Stroke
10.1134/s1819712420020038 · 2020 · External reference
Polyamine Catabolism Is Enhanced after Traumatic Brain Injury
10.1089/neu.2009.1097 · 2010 · External reference
Changes in brain polyamine levels following head injury
10.1016/0014-4886(92)90126-b · 1992 · External reference
Contribution of polyamine oxidase to brain injury after trauma
10.3171/jns.1999.90.6.1078 · 1999 · External reference
Polyamine–nucleic acid interactions and the effects on structure in oriented DNA fibers
10.1093/nar/30.2.419 · 2002 · External reference
A perspective of polyamine metabolism
10.1042/bj20031327 · 2003 · External reference
Modulation of cellular function by polyamines
10.1016/j.biocel.2009.07.009 · 2010 · External reference
Independent roles of eIF5A and polyamines in cell proliferation
10.1042/bj20041477 · 2005 · External reference
Astrocytes, not neurons, show most prominent staining for spermidine/spermine-like immunoreactivity in adult rat brain
10.1002/(sici)1098-1136(199702)19:2<171::aid-glia8>3.0.co;2-3 · 1997 · External reference
Changes in the Localization of Polyamine Spermidine in the Rat Retina with Age
10.3390/biomedicines11041008 · 2023 · External reference
Spermine/Spermidine Is Expressed by Retinal Glial (Mü ller) Cells and Controls Distinct K Channels of Their Membrane
10.1002/(sici)1098-1136(199807)23:3<209::aid-glia4>3.0.co;2-# · 1998 · External reference
Spatial Distribution of Spermine/Spermidine Content and K-Current Rectification in Frog Retinal Glial (Mü ller) Cells
10.1002/(sici)1098-1136(200007)31:1<84::aid-glia80>3.0.co;2-7 · 2000 · External reference
Age-Dependent Redistribution of the Life-Important Enzyme in the Retina: Adult Müller Glial Cells’ Endfeet Lack Spermine Synthase Expression
10.3390/biom15101374 · 2025 · External reference
Spermidine Synthase Localization in Retinal Layers: Early Age Changes
10.3390/ijms25126458 · 2024 · External reference
Cellular and subcellular rat brain spermidine synthase expression patterns suggest region-specific roles for polyamines, including cerebellar pre-synaptic function
10.1111/j.1471-4159.2007.04770.x · 2007 · External reference
Unique Chemistry, Intake, and Metabolism of Polyamines in the Central Nervous System (CNS) and Its Body
10.3390/biom12040501 · 2022 · External reference
Ornithine decarboxylase-like immunoreactivity in rat spinal motoneurons and motoric nerves
10.1016/0006-8993(93)90867-m · 1993 · External reference
Evidence for the existence of ornithine decarboxylase-immunoreactive neurons in the rat brain
10.1016/0304-3940(87)90413-7 · 1987 · External reference
Astrocytic urea cycle detoxifies Aβ-derived ammonia while impairing memory in Alzheimer’s disease
10.1016/j.cmet.2022.05.011 · 2022 · External reference
N-methyl-D-aspartate receptor excitotoxicity involves activation of polyamine synthesis: protection by alpha-difluoromethylornithine
10.1111/j.1471-4159.1993.tb05858.x · 1993 · External reference
A role for polyamines in retinal ganglion cell excitotoxic death
10.1111/j.1471-4159.2007.04843.x · 2007 · External reference
Changes in polyamine levels and spectrin degradation following kainate-induced seizure activity: Effect of difluoromethylornithine
10.1016/0014-4886(92)90013-g · 1992 · External reference
Neuronal and glial responses to polyamines in the ischemic brain
10.2174/1567202054368335 · 2005 · External reference
The Role of Polyamine Metabolism in Neuronal Injury Following Cerebral Ischemia
10.1017/s0317167100006247 · 2009 · External reference
Click Chemistry: Diverse Chemical Function from a Few Good Reactions
2021 · External reference
A stepwise huisgen cycloaddition process: copper(I)-catalyzed regioselective “ligation” of azides and terminal alkynes
10.1002/1521-3773(20020715)41:14<2596::aid-anie2596>3.0.co;2-4 · 2002 · External reference
Peptidotriazoles on Solid Phase: [1,2,3]-Triazoles by Regiospecific Copper(I)-Catalyzed 1,3-Dipolar Cycloadditions of Terminal Alkynes to Azides
10.1021/jo011148j · 2002 · External reference
Minimal-tag polyamines for in situ probing of their intracellular distribution
10.1039/d5cc06304c · 2026 · External reference
ATP13A4 Upregulation Drives the Elevated Polyamine Transport System in the Breast Cancer Cell Line MCF7
10.3390/biom13060918 · 2023 · External reference
The relationship between levels and rates of synthesis of polyamines during mammalian cell cycle
10.1016/0024-3205(81)90382-9 · 1981 · External reference
Expression of polyamine transporter activity during B lymphocyte cell cycle progression
10.4049/jimmunol.150.10.4218 · 1993 · External reference
Polyamines in cell growth and cell death: molecular mechanisms and therapeutic applications
10.1007/pl00000852 · 2001 · External reference
Critical Role of Astrocytic Polyamine and GABA Metabolism in Epileptogenesis
10.3389/fncel.2021.787319 · 2022 · External reference
SLC45A4 is a pain gene encoding a neuronal polyamine transporter
10.1038/s41586-025-09326-y · 2025 · External reference
ATP13A2 deficiency disrupts lysosomal polyamine export
10.1038/s41586-020-1968-7 · 2020 · External reference
Hereditary parkinsonism with dementia is caused by mutations in ATP13A2, encoding a lysosomal type 5 P-type ATPase
10.1038/ng1884 · 2006 · External reference
Polyamine uptake is necessary for a normal biochemical maturation of astrocytes in culture
10.1097/00001756-200206120-00022 · 2002 · External reference
Polyamine uptake in cultured astrocytes: characterization and modulation by protein kinases
10.1046/j.1471-4159.2000.0751917.x · 2000 · External reference
Uptake of Biotinylated Spermine in Astrocytes: Effect of Cx43 siRNA, HIV-Tat Protein and Polyamine Transport Inhibitor on Polyamine Uptake
10.3390/biom11081187 · 2021 · External reference
10.1038/s41467-026-76132-z · 2026 · Admitted local publication
Polyamine transport, accumulation, and release in brain
10.1046/j.1471-4159.2003.01558.x · 2003 · External reference
Polyamine uptake in cultured cerebellar granule neurons
10.1016/j.neuint.2003.08.007 · 2004 · External reference
The course of putrescine immunocytochemical appearance in neurons, astroglia and microglia in rat brain cultures
10.1016/s0304-3940(99)00375-4 · 1999 · External reference
ATP13A3 is a major component of the enigmatic mammalian polyamine transport system
10.1074/jbc.ra120.013908 · 2021 · External reference
Sublayer- and cell-type-specific neurodegenerative transcriptional trajectories in hippocampal sclerosis
10.1016/j.celrep.2021.109229 · 2021 · External reference
As Verified with the Aid of Biotinylated Spermine, the Brain Cannot Take up Polyamines from the Bloodstream Leaving It Solely Dependent on Local Biosynthesis
10.3390/biom13071114 · 2023 · External reference
Characterization of polyamines having agonist, antagonist, and inverse agonist effects at the polyamine recognition site of the NMDA receptor
10.1016/0896-6273(90)90309-4 · 1990 · External reference
Interactions of polyamines with ion channels
10.1042/bj3250289 · 1997 · External reference
Transcriptional Regulation of Neuronal Polarity and Morphogenesis in the Mammalian Brain
10.1016/j.neuron.2011.09.018 · 2011 · External reference
Polyamines, chromatin structure and transcription
10.1002/bies.950150811 · 1993 · External reference
Elevated levels of polyamines alter chromatin in murine skin and tumors without global changes in nucleosome acetylation
10.1016/s0014-4827(03)00352-5 · 2003 · External reference
Hypoxia Mimetic Agents for Ischemic Stroke
10.3389/fcell.2018.00175 · 2018 · External reference
Selective neuronal vulnerability of human hippocampal CA1 neurons: lesion evolution, temporal course, and pattern of hippocampal damage in diffusion-weighted MR imaging
10.1038/jcbfm.2015.137 · 2015 · External reference
Quantification of subfield pathology in hippocampal sclerosis: A systematic review and meta-analysis
10.1016/j.eplepsyres.2014.07.003 · 2014 · External reference
There is differential loss of pyramidal cells from the human hippocampus with survival after blunt head injury
10.1093/jnen/62.3.272 · 2003 · External reference
Mitochondrial Metabolism behind Region-Specific Resistance to Ischemia-Reperfusion Injury in Gerbil Hippocampus. Role of PKCβII and Phosphate-Activated Glutaminase
10.3390/ijms22168504 · 2021 · External reference
Regional difference of neuronal vulnerability in the murine hippocampus after transient forebrain ischemia
10.1016/s0006-8993(00)02319-2 · 2000 · External reference
