Research graph
References from Neurofibrillary tangle deposition in primary idiotypic isocortices using flortaucipir PET in histopathologically confirmed Alzheimer’s disease. Local targets link to admitted publications; unresolved targets remain external evidence.
Alzheimer's disease
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1970 · External reference
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10.1093/brain/awm213 · 2007 · External reference
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10.1016/s1474-4422(14)70090-0 · 2014 · External reference
New insights into atypical Alzheimer's disease in the era of biomarkers
10.1016/s1474-4422(20)30440-3 · 2021 · External reference
Alzheimer's disease clinical variants show distinct regional patterns of neurofibrillary tangle accumulation
10.1007/s00401-019-02036-6 · 2019 · External reference
Four distinct trajectories of tau deposition identified in Alzheimer's disease
10.1038/s41591-021-01309-6 · 2021 · External reference
[(18) F]AV-1451 clustering of entorhinal and cortical uptake in Alzheimer's disease
10.1002/ana.25142 · 2018 · External reference
The Consortium to Establish a Registry for Alzheimer's Disease (CERAD). Part II. Standardization of the neuropathologic assessment of Alzheimer's disease
10.1212/wnl.41.4.479 · 1991 · External reference
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10.1001/archneur.1985.04060100083029 · 1985 · External reference
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1997 · External reference
Phases of A beta-deposition in the human brain and its relevance for the development of AD
10.1212/wnl.58.12.1791 · 2002 · External reference
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10.1007/bf00308809 · 1991 · External reference
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10.1016/s0197-4580(97)00056-0 · 1997 · External reference
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10.1093/brain/121.6.1013 · 1998 · External reference
The Human Brainnetome Atlas: A New Brain Atlas Based on Connectional Architecture
10.1093/cercor/bhw157 · 2016 · External reference
Defined neurofilament, tau, and beta-amyloid precursor protein epitopes distinguish Alzheimer from non-Alzheimer senile plaques
10.1073/pnas.87.6.2249 · 1990 · External reference
Molecular neuropathology of Alzheimer's disease: in situ hybridization studies
10.1007/bf00733642 · 1990 · External reference
[(18)F]T807, a novel tau positron emission tomography imaging agent for Alzheimer's disease
10.1016/j.jalz.2012.11.008 · 2013 · External reference
In vivo imaging of amyloid deposition in Alzheimer disease using the radioligand 18F-AV-45 (florbetapir [corrected] F 18)
10.2967/jnumed.109.069088 · 2010 · External reference
Imaging brain amyloid in Alzheimer's disease with Pittsburgh Compound-B
10.1002/ana.20009 · 2004 · External reference
PET of brain amyloid and tau in mild cognitive impairment
10.1056/nejmoa054625 · 2006 · External reference
Discovery and preclinical characterization of [(18)F]PI-2620, a next-generation tau PET tracer for the assessment of tau pathology in Alzheimer's disease and other tauopathies
10.1007/s00259-019-04397-2 · 2019 · External reference
Preclinical Characterization of 18F-MK-6240, a Promising PET Tracer for In Vivo Quantification of Human Neurofibrillary Tangles
10.2967/jnumed.115.171678 · 2016 · External reference
An autoradiographic evaluation of AV-1451 Tau PET in dementia
10.1186/s40478-016-0315-6 · 2016 · External reference
[F-18]-AV-1451 binding correlates with postmortem neurofibrillary tangle Braak staging
10.1007/s00401-017-1740-8 · 2017 · External reference
Characterization of tau positron emission tomography tracer [18F]AV-1451 binding to postmortem tissue in Alzheimer's disease, primary tauopathies, and other dementias
10.1016/j.jalz.2016.01.003 · 2016 · External reference
Sensitivity-Specificity of Tau and Amyloid β Positron Emission Tomography in Frontotemporal Lobar Degeneration
10.1002/ana.25893 · 2020 · External reference
Flortaucipir PET uncovers relationships between tau and amyloid-beta in primary age-related tauopathy and Alzheimer's disease
10.1126/scitranslmed.ado8076 · 2024 · External reference
Association of in vivo retention of [(18)f] flortaucipir pet with tau neuropathology in corresponding brain regions
10.1007/s00401-024-02801-2 · 2024 · External reference
Positron Emission Tomography Imaging With [18F]flortaucipir and Postmortem Assessment of Alzheimer Disease Neuropathologic Changes
10.1001/jamaneurol.2020.0528 · 2020 · External reference
18F-flortaucipir PET to autopsy comparisons in Alzheimer's disease and other neurodegenerative diseases
10.1093/brain/awaa276 · 2020 · External reference
Investigating the feasibility of (18)F-flortaucipir PET imaging in the antemortem diagnosis of primary age-related tauopathy (PART): An observational imaging-pathological study
10.1002/alz.14301 · 2024 · External reference
Identifying early changes in imaging, plasma, and digital cognitive biomarkers that correspond to Alzheimer's disease pathology in the presence of autopsy-confirmed co-pathologies
10.1002/alz.71092 · 2026 · External reference
Association of [(18)F]Flortaucipir-PET and Plasma p-Tau217 With Tau Neuropathology in Alzheimer Disease and Other Neurodegenerative Disorders
10.1212/wnl.0000000000214576 · 2026 · External reference
Optimum Differentiation of Frontotemporal Lobar Degeneration from Alzheimer Disease Achieved with Cross-Sectional Tau Positron Emission Tomography
10.1002/ana.26479 · 2022 · External reference
National Institute on Aging-Alzheimer's Association guidelines for the neuropathologic assessment of Alzheimer's disease: a practical approach
10.1007/s00401-011-0910-3 · 2012 · External reference
Neuropathologic diagnostic and nosologic criteria for frontotemporal lobar degeneration: consensus of the Consortium for Frontotemporal Lobar Degeneration
10.1007/s00401-007-0237-2 · 2007 · External reference
Tau positron emission tomographic imaging in aging and early Alzheimer disease
10.1002/ana.24546 · 2016 · External reference
PET Imaging of Tau Deposition in the Aging Human Brain
10.1016/j.neuron.2016.01.028 · 2016 · External reference
Distinct binding of PET ligands PBB3 and AV-1451 to tau fibril strains in neurodegenerative tauopathies
2017 · External reference
Laminar and regional distributions of neurofibrillary tangles and neuritic plaques in Alzheimer's disease: a quantitative study of visual and auditory cortices
10.1523/jneurosci.07-06-01799.1987 · 1987 · External reference
Anatomical correlates of the distribution of the pathological changes in the neocortex in Alzheimer disease
10.1073/pnas.82.13.4531 · 1985 · External reference
Apical dendrite degeneration, a novel cellular pathology for Betz cells in ALS
10.1038/srep41765 · 2017 · External reference
Transmission and spreading of tauopathy in transgenic mouse brain
10.1038/ncb1901 · 2009 · External reference
Widespread tau seeding activity at early Braak stages
10.1007/s00401-016-1644-z · 2017 · External reference
The human entorhinal cortex: normal morphology and lamina-specific pathology in various diseases
10.1016/0168-0102(92)90014-4 · 1992 · External reference
Clinically concordant variations of Alzheimer pathology in aphasic versus amnestic dementia
10.1093/brain/aws076 · 2012 · External reference
In vivo Patterns of Tau Pathology, Amyloid-beta Burden, and Neuronal Dysfunction in Clinical Variants of Alzheimer's Disease
10.3233/jad-160316 · 2017 · External reference
MRI and flortaucipir relationships in Alzheimer's phenotypes are heterogeneous
10.1002/acn3.51038 · 2020 · External reference
Tau PET patterns mirror clinical and neuroanatomical variability in Alzheimer's disease
10.1093/brain/aww027 · 2016 · External reference
Longitudinal neuroimaging biomarkers differ across Alzheimer's disease phenotypes
10.1093/brain/awaa155 · 2020 · External reference
Relationships between flortaucipir PET tau binding and amyloid burden, clinical diagnosis, age and cognition
2017 · External reference
The role of age on tau PET uptake and gray matter atrophy in atypical Alzheimer's disease
10.1016/j.jalz.2018.12.016 · 2019 · External reference
AV-1451 tau and beta-amyloid positron emission tomography imaging in dementia with Lewy bodies
10.1002/ana.24825 · 2017 · External reference
Distinct patterns of amyloid-dependent tau accumulation in Lewy body diseases
10.1002/mds.27252 · 2018 · External reference
Is the pathology of posterior cortical atrophy clinically predictable?
10.1515/revneuro-2022-0003 · 2022 · External reference
Motor features in posterior cortical atrophy and their imaging correlates
10.1016/j.neurobiolaging.2014.05.028 · 2014 · External reference
Longitudinal tau-PET uptake and atrophy in atypical Alzheimer's disease
10.1016/j.nicl.2019.101823 · 2019 · External reference
Longitudinal tau PET in ageing and Alzheimer's disease
10.1093/brain/awy059 · 2018 · External reference
The accumulation rate of tau aggregates is higher in females and younger amyloid-positive subjects
10.1093/brain/awaa327 · 2020 · External reference
Sex Differences in Longitudinal Tau-PET in Preclinical Alzheimer Disease: A Meta-Analysis
10.1001/jamaneurol.2025.0013 · 2025 · External reference
Sex differences in the association of Alzheimer's disease biomarkers and cognition in a multicenter memory clinic study
10.1186/s13195-025-01684-z · 2025 · External reference
Sex-specific modulation of amyloid-beta on tau phosphorylation underlies faster tangle accumulation in females
10.1093/brain/awad397 · 2024 · External reference
Sex and APOE epsilon4 carrier effects on atrophy, amyloid PET, and tau PET burden in early-onset Alzheimer's disease
2023 · External reference
Menopause Status Moderates Sex Differences in Tau Burden: A Framingham PET Study
10.1002/ana.26382 · 2022 · External reference
APOE epsilon4 influences medial temporal atrophy and tau deposition in atypical Alzheimer's disease
10.1002/alz.12711 · 2023 · External reference
Association of APOE4 and Clinical Variability in Alzheimer Disease With the Pattern of Tau- and Amyloid-PET
10.1212/wnl.0000000000011270 · 2021 · External reference
Effect of APOE epsilon4 genotype on amyloid-beta and tau accumulation in Alzheimer's disease
10.1186/s13195-020-00710-6 · 2020 · External reference
APOE effects on regional tau in preclinical Alzheimer's disease
10.1186/s13024-022-00590-4 · 2023 · External reference
Data-driven decomposition and staging of flortaucipir uptake in Alzheimer's disease
10.1002/alz.13769 · 2024 · External reference
The Mayo Clinic Study of Aging: design and sampling, participation, baseline measures and sample characteristics
10.1159/000115751 · 2008 · External reference
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10.1016/0022-3956(75)90026-6 · 1975 · External reference
A new clinical scale for the staging of dementia
10.1192/bjp.140.6.566 · 1982 · External reference
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10.1016/j.jalz.2017.01.014 · 2017 · External reference
The behavioural/dysexecutive variant of Alzheimer's disease: clinical, neuroimaging and pathological features
10.1093/brain/awv191 · 2015 · External reference
Diagnosis and management of dementia with Lewy bodies: Fourth consensus report of the DLB Consortium
10.1212/wnl.0000000000004058 · 2017 · External reference
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10.1212/wnl.43.2.250 · 1993 · External reference
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10.1093/brain/awr179 · 2011 · External reference
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10.1212/wnl.0b013e31821103e6 · 2011 · External reference
Primary progressive aphasia--differentiation from Alzheimer's disease
10.1002/ana.410220414 · 1987 · External reference
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10.1212/wnl.0b013e31827f0fd1 · 2013 · External reference
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10.1002/mds.26987 · 2017 · External reference
Single-day apolipoprotein E genotyping
10.1016/0165-0270(94)90168-6 · 1994 · External reference
National Institute on Aging-Alzheimer's Association guidelines for the neuropathologic assessment of Alzheimer's disease
10.1016/j.jalz.2011.10.007 · 2012 · External reference
A harmonized classification system for FTLD-TDP pathology
10.1007/s00401-011-0845-8 · 2011 · External reference
Unresolved reference
2017 · External reference
brms: An R Package for Bayesian Multilevel Models Using Stan
10.18637/jss.v080.i01 · 2017 · External reference