Research graph
References from A biomaterials roadmap from retinoic acid biology to kidney regenerative therapy. Local targets link to admitted publications; unresolved targets remain external evidence.
The axolotl kidney: a novel model to study kidney regeneration
10.1016/j.kint.2023.05.020 · 2023 · External reference
Renal progenitors: an evolutionary conserved strategy for kidney regeneration
10.1038/nrneph.2012.290 · 2013 · External reference
Mechanisms of maladaptive repair after AKI leading to accelerated kidney ageing and CKD
10.1038/nrneph.2015.3 · 2015 · External reference
Epithelial proliferation and cell cycle dysregulation in kidney injury and disease
10.1016/j.kint.2021.03.024 · 2021 · External reference
Predicting proximal tubule failed repair drivers through regularized regression analysis of single cell multiomic sequencing
10.1038/s41467-024-45706-0 · 2024 · External reference
Retinoic acid in development: towards an integrated view
10.1038/nrg2340 · 2008 · External reference
Retinoic acid signaling pathways
10.1242/dev.167502 · 2019 · External reference
Retinoic acid receptor α activity in proximal tubules prevents kidney injury and fibrosis
10.1073/pnas.2311803121 · 2024 · External reference
Evolutionary Transition in the Regulation of Vertebrate Pronephros Development: A New Role for Retinoic Acid
10.3390/cells11081304 · 2022 · External reference
Vitamin A and retinoid signaling in the kidneys
10.1016/j.pharmthera.2023.108481 · 2023 · External reference
Myofibroblasts acquire retinoic acid-producing ability during fibroblast-to-myofibroblast transition following kidney injury
10.1016/j.kint.2018.10.017 · 2019 · External reference
Inhibition of retinoic acid signaling in proximal tubular epithelial cells protects against acute kidney injury
10.1172/jci.insight.173144 · 2023 · External reference
Activation of fetal-like molecular programs during regeneration in the intestine and beyond
10.1016/j.stem.2024.05.009 · 2024 · External reference
Reactivation of embryonic genetic programs in tissue regeneration and disease
10.1038/s41588-023-01526-4 · 2023 · External reference
Reactivation of mammalian regeneration by turning on an evolutionarily disabled genetic switch
10.1126/science.adp0176 · 2025 · External reference
Synthetic Retinoids Beyond Cancer Therapy
10.1146/annurev-pharmtox-052120-104428 · 2022 · External reference
A non-retinol retinoic acid receptor-γ (RAR-γ/NR1B3) selective agonist, tectorigenin, can effectively inhibit the ultraviolet A-induced skin damage
10.1111/bph.15902 · 2022 · External reference
MTHFD1 is critical for the negative regulation of retinoic acid receptor signalling in anencephaly
10.1093/brain/awad084 · 2023 · External reference
Solubilization techniques used for poorly water-soluble drugs
10.1016/j.apsb.2024.08.027 · 2024 · External reference
Physicochemical and structural evaluation of microparticles in tretinoin topical gels
10.1016/j.ijpharm.2022.121748 · 2022 · External reference
Retinoic acid-related orphan receptor gamma t (RORγt) inverse agonists/antagonists for the treatment of inflammatory diseases - where are we presently?
10.1080/17460441.2021.1948833 · 2021 · External reference
The yin and yang of retinoic acid signaling in kidney diseases
10.1172/jci141712 · 2020 · External reference
Patterning a complex organ: branching morphogenesis and nephron segmentation in kidney development
10.1016/j.devcel.2010.04.008 · 2010 · External reference
The kidney stroma in development and disease
10.1038/s41581-025-00985-8 · 2025 · External reference
Retinoic acid signaling maintains epithelial and mesenchymal progenitors in the developing mouse ureter
10.1038/s41598-017-14790-2 · 2017 · External reference
Expansion of the renal capsular stroma, ureteric bud branching defects and cryptorchidism in mice with Wilms tumor 1 gene deletion in the stromal compartment of the developing kidney
10.1002/path.5518 · 2020 · External reference
Delayed onset of smooth muscle cell differentiation leads to hydroureter formation in mice with conditional loss of the zinc finger transcription factor gene Gata2 in the ureteric mesenchyme
10.1002/path.5270 · 2019 · External reference
Stromal cells mediate retinoid-dependent functions essential for renal development
10.1242/dev.126.6.1139 · 1999 · External reference
Spatially patterned kidney assembloids recapitulate progenitor self-assembly and enable high-fidelity in vivo disease modeling
10.1016/j.stem.2025.08.013 · 2025 · External reference
DevKidCC allows for robust classification and direct comparisons of kidney organoid datasets
10.1186/s13073-022-01023-z · 2022 · External reference
Traditional Chinese Medicine and renal regeneration: experimental evidence and future perspectives
10.1186/s13020-024-00935-9 · 2024 · External reference
Activated SOX9+ renal epithelial cells promote kidney repair through secreting factors
10.1111/cpr.13394 · 2023 · External reference
Zinc finger protein 24-dependent transcription factor SOX9 up-regulation protects tubular epithelial cells during acute kidney injury
10.1016/j.kint.2023.02.026 · 2023 · External reference
Inhibition of HIF-prolyl hydroxylase promotes renal tubule regeneration via the reprogramming of renal proximal tubular cells
10.1038/s41401-024-01445-y · 2025 · External reference
Enhancing regeneration after acute kidney injury by promoting cellular dedifferentiation in zebrafish
10.1242/dmm.037390 · 2019 · External reference
Retinoic acid receptor-beta prevents cisplatin-induced proximal tubular cell death
10.1016/j.bbadis.2020.165795 · 2020 · External reference
Reconstituting human somitogenesis in vitro
10.1038/s41586-022-05649-2 · 2023 · External reference
All-trans retinoic acid modulates pigmentation, neuroretinal maturation, and corneal transparency in human multiocular organoids
10.1186/s13287-022-03053-1 · 2022 · External reference
The role of Wnt signaling in the development of the epiblast and axial progenitors
10.1016/bs.ctdb.2023.01.010 · 2023 · External reference
Retinoic acid and RARγ maintain satellite cell quiescence through regulation of translation initiation
10.1038/s41419-022-05284-9 · 2022 · External reference
The involvement of the Wnt/β-catenin signaling cascade in fibrosis progression and its therapeutic targeting by relaxin
10.1016/j.bcp.2024.116130 · 2024 · External reference
Developmental biology-inspired tissue engineering by combining organoids and 3D bioprinting
10.1016/j.copbio.2022.102832 · 2022 · External reference
Developmental Biology-Based 3D Bioprinting: An Off-the-Shelf Strategy to Induce Tissue Regeneration
10.1021/acsbiomaterials.5c00213 · 2025 · External reference
Developmentally inspired synthetic kidney engineering
10.1038/s41587-026-03011-9 · 2026 · External reference
Developmental engineering the kidney: leveraging principles of morphogenesis for renal regeneration
10.1002/bdrc.20224 · 2012 · External reference
Zebrafish nephrogenesis involves dynamic spatiotemporal expression changes in renal progenitors and essential signals from retinoic acid and irx3b
10.1002/dvdy.22691 · 2011 · External reference
Expression of retinoic acid-synthesizing and -metabolizing enzymes during nephrogenesis in the rat
10.1016/j.modgep.2004.08.005 · 2004 · External reference
The emerging role of hepatocyte growth factor in renal diseases
10.3109/10799893.2015.1080275 · 2016 · External reference
Prevention of acute ischemic renal failure by targeted delivery of growth factors to the proximal tubule in transgenic mice: the efficacy of parathyroid hormone-related protein and hepatocyte growth factor
10.1097/01.asn.0000102470.12285.c6 · 2004 · External reference
BMP7 in kidney development and disease: a multilayer regulatory network integrating inflammation, fibrosis, and regeneration
10.1186/s44505-026-00002-0 · 2026 · External reference
The activin-follistatin system: Key regulator of kidney development, regeneration, inflammation, and fibrosis
10.1016/j.cytogfr.2024.11.004 · 2025 · External reference
Tubule-Derived Follistatin Is Increased in the Urine of Rats with Renal Ischemia and Reflects the Severity of Acute Tubular Damage
10.3390/cells12050801 · 2023 · External reference
Retinoic Acid Signaling Coordinates Macrophage-Dependent Injury and Repair after AKI
10.1681/asn.2014111108 · 2016 · External reference
Retinoic Acid Organizes the Zebrafish Vagus Motor Topographic Map via Spatiotemporal Coordination of Hgf/Met Signaling
10.1016/j.devcel.2020.03.017 · 2020 · External reference
Enhancing Retinoic Acid-mediated Effects Through Inhibition of CYP26A1, CYP26B1 and HGF Signaling in Neuroblastoma Cells
10.21873/anticanres.17249 · 2024 · External reference
Regulation of BMP-7 expression by retinoic acid and prostaglandin E(2)
10.1002/jcp.10048 · 2002 · External reference
Potential Strategies for Kidney Regeneration With Stem Cells: An Overview
10.3389/fcell.2022.892356 · 2022 · External reference
Twenty-year panoramic review of stem cells research in kidney diseases (2005-2025): a bibliometric and clinical trial-based exploration
10.1097/js9.0000000000002479 · 2025 · External reference
Cell-based regenerative medicine for renovascular disease
10.1016/j.molmed.2021.06.004 · 2021 · External reference
Adult Mouse Kidney Stem Cells Orchestrate the De Novo Assembly of a Nephron via Sirt2-Modulated Canonical Wnt/β-Catenin Signaling
2022 · External reference
Biomaterials-Based Cell Therapy for Myocardial Tissue Regeneration
10.1002/adhm.202202699 · 2023 · External reference
A systematic review and meta-analysis of cell-based interventions in experimental diabetic kidney disease
10.1002/sctm.19-0419 · 2021 · External reference
How Stem and Progenitor Cells Can Affect Renal Diseases
10.3390/cells13171460 · 2024 · External reference
Stem cells for treatment of liver fibrosis/cirrhosis: clinical progress and therapeutic potential
10.1186/s13287-022-03041-5 · 2022 · External reference
Stem/progenitor cell in kidney: characteristics, homing, coordination, and maintenance
10.1186/s13287-021-02266-0 · 2021 · External reference
All-trans retinoic acid pretreatment of mesenchymal stem cells enhances the therapeutic effect on acute kidney injury
10.1186/s12964-024-01671-1 · 2024 · External reference
Possible Underlying Mechanisms for the Renoprotective Effect of Retinoic Acid-Pretreated Wharton's Jelly Mesenchymal Stem Cells against Renal Ischemia/Reperfusion Injury
10.3390/cells11131997 · 2022 · External reference
Targeting cellular senescence in kidney diseases and aging: A focus on mesenchymal stem cells and their paracrine factors
10.1186/s12964-024-01968-1 · 2024 · External reference
WT1(+) glomerular parietal epithelial progenitors promote renal proximal tubule regeneration after severe acute kidney injury
10.7150/thno.79326 · 2023 · External reference
Molecular Mechanisms of Renal Progenitor Regulation: How Many Pieces in the Puzzle?
10.3390/cells10010059 · 2021 · External reference
Role of mitochondria in endogenous renal repair
10.1042/cs20231331 · 2024 · External reference
Gender and Renal Insufficiency: Opportunities for Their Therapeutic Management?
10.3390/cells11233820 · 2022 · External reference
Mitochondrial-Derived Signaling Mediates Differentiation of Parietal Epithelial Cells into Podocytes
10.1089/ars.2024.0580 · 2025 · External reference
Retinoic acid improves nephrotoxic serum-induced glomerulonephritis through activation of podocyte retinoic acid receptor α
10.1016/j.kint.2017.04.026 · 2017 · External reference
Single-cell RNA sequencing data locate ALDH1A2-mediated retinoic acid synthetic pathway to glomerular parietal epithelial cells
10.3389/ebm.2024.10167 · 2024 · External reference
Proteinuria impairs podocyte regeneration by sequestering retinoic acid
10.1681/asn.2012090950 · 2013 · External reference
Selective induction of human renal interstitial progenitor-like cell lineages from iPSCs reveals development of mesangial and EPO-producing cells
10.1016/j.celrep.2023.113602 · 2024 · External reference
Kidney development at a glance: metabolic regulation of renal progenitor cells
10.1016/bs.ctdb.2024.11.009 · 2025 · External reference
A coordinated progression of progenitor cell states initiates urinary tract development
10.1038/s41467-021-22931-5 · 2021 · External reference
Drosophila renal stem cells enhance fitness by delayed remodeling of adult Malpighian tubules
2022 · External reference
All-Trans Retinoic Acid Attenuates Fibrotic Processes by Downregulating TGF-β1/Smad3 in Early Diabetic Nephropathy
10.3390/biom9100525 · 2019 · External reference
Renal tubular-derived retinoic acid drives renal fibrosis via a RAI14-TRIOBP-YAP mechanotransduction axis
10.1016/j.cellsig.2025.112246 · 2026 · External reference
Disparate roles of retinoid acid signaling molecules in kidney disease
10.1152/ajprenal.00045.2021 · 2021 · External reference
Podocyte-derived soluble RARRES1 drives kidney disease progression through direct podocyte and proximal tubular injury
10.1016/j.kint.2024.04.011 · 2024 · External reference
Preventing MMP23-mediated cleavage of podocyte RARRES1: a novel strategy to halt chronic kidney disease progression?
10.1016/j.kint.2024.05.004 · 2024 · External reference
Soluble RARRES1 induces podocyte apoptosis to promote glomerular disease progression
10.1172/jci140155 · 2020 · External reference
Advances and challenges in retinoid delivery systems in regenerative and therapeutic medicine
10.1038/s41467-020-18042-2 · 2020 · External reference
Anticancer activity of all-trans retinoic acid-loaded liposomes on human thyroid carcinoma cells
10.1016/j.colsurfb.2016.10.052 · 2017 · External reference
The rates of major malformations after gestational exposure to isotretinoin: a systematic review and meta-analysis
10.5468/ogs.20373 · 2021 · External reference
Retinoic acid and depressive disorders: Evidence and possible neurobiological mechanisms
10.1016/j.neubiorev.2020.02.013 · 2020 · External reference
Astrocytic RARγ mediates hippocampal astrocytosis and neurogenesis deficits in chronic retinoic acid-induced depression
10.1038/s41386-024-01983-3 · 2024 · External reference
Fabrication of All-Trans Retinoic Acid loaded Chitosan/Tripolyphosphate Lipid Hybrid Nanoparticles as a Novel Oral Delivery Approach for Management of Diabetic Nephropathy in Rats
10.1016/j.xphs.2021.05.007 · 2021 · External reference
Improving kidney targeting: The influence of nanoparticle physicochemical properties on kidney interactions
10.1016/j.jconrel.2021.04.016 · 2021 · External reference
A quantitative review of nanotechnology-based therapeutics for kidney diseases
10.1002/wnan.1953 · 2024 · External reference
Effects of mycophenolic acid-glucosamine conjugates on the base of kidney targeted drug delivery
10.1016/j.ijpharm.2013.07.064 · 2013 · External reference
Folate Receptor-Mediated Renal-Targeting Nanoplatform for the Specific Delivery of Triptolide to Treat Renal Ischemia/Reperfusion Injury
10.1021/acsbiomaterials.9b00119 · 2019 · External reference
High-density lipoprotein nanoparticles spontaneously target to damaged renal tubules and alleviate renal fibrosis by remodeling the fibrotic niches
10.1038/s41467-025-56223-z · 2025 · External reference
Renal Targeting: Peptide-Based Drug Delivery to Proximal Tubule Cells
10.1021/acs.bioconjchem.6b00057 · 2016 · External reference
Kidney targeted delivery of asiatic acid using a FITC labeled renal tubular-targeting peptide modified PLGA-PEG system
10.1016/j.ijpharm.2020.119455 · 2020 · External reference
Design, Synthesis, and Renal Targeting of Methylprednisolone-Lysozyme
10.3390/ijms21061922 · 2020 · External reference
A rationally designed injury kidney targeting peptide library and its application in rescuing acute kidney injury
10.1126/sciadv.adt3943 · 2025 · External reference
Multiplexed PLGA scaffolds with nitric oxide-releasing zinc oxide and melatonin-modulated extracellular vesicles for severe chronic kidney disease
10.1016/j.jare.2024.03.018 · 2025 · External reference
Nanocarrier of Pin1 inhibitor based on supercritical fluid technology inhibits cancer metastasis by blocking multiple signaling pathways
10.1093/rb/rbad014 · 2023 · External reference
Clot-Targeted Antithrombotic Liposomal Nanomedicine Containing High Content of H(2)O(2)-Activatable Hybrid Prodrugs
10.1021/acsami.2c20750 · 2023 · External reference
Recent advances in applications of nanoparticles and decellularized ECM for organoid engineering
2025 · External reference
Nitric oxide-modulating biomaterials for therapeutic Immunoengineering
10.1016/j.addr.2025.115718 · 2025 · External reference
Extracellular vesicles as next generation immunotherapeutics
10.1016/j.semcancer.2023.02.002 · 2023 · External reference
Extracellular vesicle therapy in neurological disorders
10.1186/s12929-024-01075-w · 2024 · External reference
TGF-β/LAMB3 axis drives ROS-dependent renal fibrosis under hypoxic conditions
10.1016/j.freeradbiomed.2025.12.024 · 2026 · External reference
Fabricating PLGA microparticles with high loads of the small molecule antioxidant N-acetylcysteine that rescue oligodendrocyte progenitor cells from oxidative stress
10.1002/bit.26443 · 2018 · External reference
Developmental engineering: design of clinically efficacious bioartificial tissues through developmental and systems biology
10.1007/s11427-017-9255-3 · 2018 · External reference
Developmental biology in bioartificial tissue design: manufacturing and regulatory considerations
10.2217/rme-2017-0126 · 2018 · External reference
3D Bioprinting of Developmentally Inspired Templates for Whole Bone Organ Engineering
10.1002/adhm.201600182 · 2016 · External reference
Cadherin-engineered microspheres enable scalable biofabrication of multilineage liver organoids
10.1016/j.tibtech.2026.03.014 · 2026 · External reference
Controlling nephron precursor differentiation to generate proximal-biased kidney organoids with emerging maturity
10.1038/s41467-025-63107-9 · 2025 · External reference
Returning to kidney development to deliver synthetic kidneys
10.1016/j.ydbio.2020.12.009 · 2021 · External reference
Mammalian kidney development: principles, progress, and projections
10.1101/cshperspect.a008300 · 2012 · External reference
Spatiotemporal manipulation of retinoic acid activity in zebrafish hindbrain development via photo-isomerization
10.1242/dev.077776 · 2012 · External reference
Size and dose of nanoparticles modulate between toxic and medicinal effect on kidney
10.1016/j.onano.2024.100200 · 2024 · External reference
Transport and interactions of nanoparticles in the kidneys
10.1038/s41578-018-0038-3 · 2018 · External reference
3D Bioprinting of Developmentally Inspired Templates for Whole Bone Organ Engineering
10.1002/adhm.201600182 · ExternalCitation · doi-reference
Biomaterials-Based Cell Therapy for Myocardial Tissue Regeneration
10.1002/adhm.202202699 · ExternalCitation · doi-reference
Developmental engineering the kidney: leveraging principles of morphogenesis for renal regeneration
10.1002/bdrc.20224 · ExternalCitation · doi-reference
Fabricating PLGA microparticles with high loads of the small molecule antioxidant N-acetylcysteine that rescue oligodendrocyte progenitor cells from oxidative stress
10.1002/bit.26443 · ExternalCitation · doi-reference
Zebrafish nephrogenesis involves dynamic spatiotemporal expression changes in renal progenitors and essential signals from retinoic acid and irx3b
10.1002/dvdy.22691 · ExternalCitation · doi-reference
Regulation of BMP-7 expression by retinoic acid and prostaglandin E(2)
10.1002/jcp.10048 · ExternalCitation · doi-reference
Delayed onset of smooth muscle cell differentiation leads to hydroureter formation in mice with conditional loss of the zinc finger transcription factor gene Gata2 in the ureteric mesenchyme
10.1002/path.5270 · ExternalCitation · doi-reference
Expansion of the renal capsular stroma, ureteric bud branching defects and cryptorchidism in mice with Wilms tumor 1 gene deletion in the stromal compartment of the developing kidney
10.1002/path.5518 · ExternalCitation · doi-reference
A systematic review and meta-analysis of cell-based interventions in experimental diabetic kidney disease
10.1002/sctm.19-0419 · ExternalCitation · doi-reference
A quantitative review of nanotechnology-based therapeutics for kidney diseases
10.1002/wnan.1953 · ExternalCitation · doi-reference
Developmental engineering: design of clinically efficacious bioartificial tissues through developmental and systems biology
10.1007/s11427-017-9255-3 · ExternalCitation · doi-reference
The role of Wnt signaling in the development of the epiblast and axial progenitors
10.1016/bs.ctdb.2023.01.010 · ExternalCitation · doi-reference
Kidney development at a glance: metabolic regulation of renal progenitor cells
10.1016/bs.ctdb.2024.11.009 · ExternalCitation · doi-reference
Nitric oxide-modulating biomaterials for therapeutic Immunoengineering
10.1016/j.addr.2025.115718 · ExternalCitation · doi-reference
Solubilization techniques used for poorly water-soluble drugs
10.1016/j.apsb.2024.08.027 · ExternalCitation · doi-reference
Retinoic acid receptor-beta prevents cisplatin-induced proximal tubular cell death
10.1016/j.bbadis.2020.165795 · ExternalCitation · doi-reference
The involvement of the Wnt/β-catenin signaling cascade in fibrosis progression and its therapeutic targeting by relaxin
10.1016/j.bcp.2024.116130 · ExternalCitation · doi-reference
Renal tubular-derived retinoic acid drives renal fibrosis via a RAI14-TRIOBP-YAP mechanotransduction axis
10.1016/j.cellsig.2025.112246 · ExternalCitation · doi-reference
Selective induction of human renal interstitial progenitor-like cell lineages from iPSCs reveals development of mesangial and EPO-producing cells
10.1016/j.celrep.2023.113602 · ExternalCitation · doi-reference
Anticancer activity of all-trans retinoic acid-loaded liposomes on human thyroid carcinoma cells
10.1016/j.colsurfb.2016.10.052 · ExternalCitation · doi-reference
Developmental biology-inspired tissue engineering by combining organoids and 3D bioprinting
10.1016/j.copbio.2022.102832 · ExternalCitation · doi-reference
The activin-follistatin system: Key regulator of kidney development, regeneration, inflammation, and fibrosis
10.1016/j.cytogfr.2024.11.004 · ExternalCitation · doi-reference
Patterning a complex organ: branching morphogenesis and nephron segmentation in kidney development
10.1016/j.devcel.2010.04.008 · ExternalCitation · doi-reference
Retinoic Acid Organizes the Zebrafish Vagus Motor Topographic Map via Spatiotemporal Coordination of Hgf/Met Signaling
10.1016/j.devcel.2020.03.017 · ExternalCitation · doi-reference
TGF-β/LAMB3 axis drives ROS-dependent renal fibrosis under hypoxic conditions
10.1016/j.freeradbiomed.2025.12.024 · ExternalCitation · doi-reference
Effects of mycophenolic acid-glucosamine conjugates on the base of kidney targeted drug delivery
10.1016/j.ijpharm.2013.07.064 · ExternalCitation · doi-reference
Kidney targeted delivery of asiatic acid using a FITC labeled renal tubular-targeting peptide modified PLGA-PEG system
10.1016/j.ijpharm.2020.119455 · ExternalCitation · doi-reference
Physicochemical and structural evaluation of microparticles in tretinoin topical gels
10.1016/j.ijpharm.2022.121748 · ExternalCitation · doi-reference
Multiplexed PLGA scaffolds with nitric oxide-releasing zinc oxide and melatonin-modulated extracellular vesicles for severe chronic kidney disease
10.1016/j.jare.2024.03.018 · ExternalCitation · doi-reference
Improving kidney targeting: The influence of nanoparticle physicochemical properties on kidney interactions
10.1016/j.jconrel.2021.04.016 · ExternalCitation · doi-reference
Retinoic acid improves nephrotoxic serum-induced glomerulonephritis through activation of podocyte retinoic acid receptor α
10.1016/j.kint.2017.04.026 · ExternalCitation · doi-reference
Myofibroblasts acquire retinoic acid-producing ability during fibroblast-to-myofibroblast transition following kidney injury
10.1016/j.kint.2018.10.017 · ExternalCitation · doi-reference
Epithelial proliferation and cell cycle dysregulation in kidney injury and disease
10.1016/j.kint.2021.03.024 · ExternalCitation · doi-reference
Zinc finger protein 24-dependent transcription factor SOX9 up-regulation protects tubular epithelial cells during acute kidney injury
10.1016/j.kint.2023.02.026 · ExternalCitation · doi-reference
The axolotl kidney: a novel model to study kidney regeneration
10.1016/j.kint.2023.05.020 · ExternalCitation · doi-reference
Podocyte-derived soluble RARRES1 drives kidney disease progression through direct podocyte and proximal tubular injury
10.1016/j.kint.2024.04.011 · ExternalCitation · doi-reference
Preventing MMP23-mediated cleavage of podocyte RARRES1: a novel strategy to halt chronic kidney disease progression?
10.1016/j.kint.2024.05.004 · ExternalCitation · doi-reference
Expression of retinoic acid-synthesizing and -metabolizing enzymes during nephrogenesis in the rat
10.1016/j.modgep.2004.08.005 · ExternalCitation · doi-reference
Cell-based regenerative medicine for renovascular disease
10.1016/j.molmed.2021.06.004 · ExternalCitation · doi-reference
Retinoic acid and depressive disorders: Evidence and possible neurobiological mechanisms
10.1016/j.neubiorev.2020.02.013 · ExternalCitation · doi-reference
Size and dose of nanoparticles modulate between toxic and medicinal effect on kidney
10.1016/j.onano.2024.100200 · ExternalCitation · doi-reference
Vitamin A and retinoid signaling in the kidneys
10.1016/j.pharmthera.2023.108481 · ExternalCitation · doi-reference
Extracellular vesicles as next generation immunotherapeutics
10.1016/j.semcancer.2023.02.002 · ExternalCitation · doi-reference
Activation of fetal-like molecular programs during regeneration in the intestine and beyond
10.1016/j.stem.2024.05.009 · ExternalCitation · doi-reference
Spatially patterned kidney assembloids recapitulate progenitor self-assembly and enable high-fidelity in vivo disease modeling
10.1016/j.stem.2025.08.013 · ExternalCitation · doi-reference
Cadherin-engineered microspheres enable scalable biofabrication of multilineage liver organoids
10.1016/j.tibtech.2026.03.014 · ExternalCitation · doi-reference
Fabrication of All-Trans Retinoic Acid loaded Chitosan/Tripolyphosphate Lipid Hybrid Nanoparticles as a Novel Oral Delivery Approach for Management of Diabetic Nephropathy in Rats
10.1016/j.xphs.2021.05.007 · ExternalCitation · doi-reference
Returning to kidney development to deliver synthetic kidneys
10.1016/j.ydbio.2020.12.009 · ExternalCitation · doi-reference
Renal Targeting: Peptide-Based Drug Delivery to Proximal Tubule Cells
10.1021/acs.bioconjchem.6b00057 · ExternalCitation · doi-reference
Clot-Targeted Antithrombotic Liposomal Nanomedicine Containing High Content of H(2)O(2)-Activatable Hybrid Prodrugs
10.1021/acsami.2c20750 · ExternalCitation · doi-reference
Developmental Biology-Based 3D Bioprinting: An Off-the-Shelf Strategy to Induce Tissue Regeneration
10.1021/acsbiomaterials.5c00213 · ExternalCitation · doi-reference
Folate Receptor-Mediated Renal-Targeting Nanoplatform for the Specific Delivery of Triptolide to Treat Renal Ischemia/Reperfusion Injury
10.1021/acsbiomaterials.9b00119 · ExternalCitation · doi-reference
Retinoic acid in development: towards an integrated view
10.1038/nrg2340 · ExternalCitation · doi-reference
Renal progenitors: an evolutionary conserved strategy for kidney regeneration
10.1038/nrneph.2012.290 · ExternalCitation · doi-reference
Mechanisms of maladaptive repair after AKI leading to accelerated kidney ageing and CKD
10.1038/nrneph.2015.3 · ExternalCitation · doi-reference
Astrocytic RARγ mediates hippocampal astrocytosis and neurogenesis deficits in chronic retinoic acid-induced depression
10.1038/s41386-024-01983-3 · ExternalCitation · doi-reference
Inhibition of HIF-prolyl hydroxylase promotes renal tubule regeneration via the reprogramming of renal proximal tubular cells
10.1038/s41401-024-01445-y · ExternalCitation · doi-reference
Retinoic acid and RARγ maintain satellite cell quiescence through regulation of translation initiation
10.1038/s41419-022-05284-9 · ExternalCitation · doi-reference
Advances and challenges in retinoid delivery systems in regenerative and therapeutic medicine
10.1038/s41467-020-18042-2 · ExternalCitation · doi-reference
A coordinated progression of progenitor cell states initiates urinary tract development
10.1038/s41467-021-22931-5 · ExternalCitation · doi-reference
Predicting proximal tubule failed repair drivers through regularized regression analysis of single cell multiomic sequencing
10.1038/s41467-024-45706-0 · ExternalCitation · doi-reference
High-density lipoprotein nanoparticles spontaneously target to damaged renal tubules and alleviate renal fibrosis by remodeling the fibrotic niches
10.1038/s41467-025-56223-z · ExternalCitation · doi-reference
Controlling nephron precursor differentiation to generate proximal-biased kidney organoids with emerging maturity
10.1038/s41467-025-63107-9 · ExternalCitation · doi-reference
Transport and interactions of nanoparticles in the kidneys
10.1038/s41578-018-0038-3 · ExternalCitation · doi-reference
The kidney stroma in development and disease
10.1038/s41581-025-00985-8 · ExternalCitation · doi-reference
Reconstituting human somitogenesis in vitro
10.1038/s41586-022-05649-2 · ExternalCitation · doi-reference
Developmentally inspired synthetic kidney engineering
10.1038/s41587-026-03011-9 · ExternalCitation · doi-reference
Reactivation of embryonic genetic programs in tissue regeneration and disease
10.1038/s41588-023-01526-4 · ExternalCitation · doi-reference
Retinoic acid signaling maintains epithelial and mesenchymal progenitors in the developing mouse ureter
10.1038/s41598-017-14790-2 · ExternalCitation · doi-reference
Role of mitochondria in endogenous renal repair
10.1042/cs20231331 · ExternalCitation · doi-reference
Retinoic acid receptor α activity in proximal tubules prevents kidney injury and fibrosis
10.1073/pnas.2311803121 · ExternalCitation · doi-reference
Retinoic acid-related orphan receptor gamma t (RORγt) inverse agonists/antagonists for the treatment of inflammatory diseases - where are we presently?
10.1080/17460441.2021.1948833 · ExternalCitation · doi-reference
Mitochondrial-Derived Signaling Mediates Differentiation of Parietal Epithelial Cells into Podocytes
10.1089/ars.2024.0580 · ExternalCitation · doi-reference
MTHFD1 is critical for the negative regulation of retinoic acid receptor signalling in anencephaly
10.1093/brain/awad084 · ExternalCitation · doi-reference
Nanocarrier of Pin1 inhibitor based on supercritical fluid technology inhibits cancer metastasis by blocking multiple signaling pathways
10.1093/rb/rbad014 · ExternalCitation · doi-reference
Prevention of acute ischemic renal failure by targeted delivery of growth factors to the proximal tubule in transgenic mice: the efficacy of parathyroid hormone-related protein and hepatocyte growth factor
10.1097/01.asn.0000102470.12285.c6 · ExternalCitation · doi-reference
Twenty-year panoramic review of stem cells research in kidney diseases (2005-2025): a bibliometric and clinical trial-based exploration
10.1097/js9.0000000000002479 · ExternalCitation · doi-reference
Mammalian kidney development: principles, progress, and projections
10.1101/cshperspect.a008300 · ExternalCitation · doi-reference
A non-retinol retinoic acid receptor-γ (RAR-γ/NR1B3) selective agonist, tectorigenin, can effectively inhibit the ultraviolet A-induced skin damage
10.1111/bph.15902 · ExternalCitation · doi-reference
Activated SOX9+ renal epithelial cells promote kidney repair through secreting factors
10.1111/cpr.13394 · ExternalCitation · doi-reference
A rationally designed injury kidney targeting peptide library and its application in rescuing acute kidney injury
10.1126/sciadv.adt3943 · ExternalCitation · doi-reference
Reactivation of mammalian regeneration by turning on an evolutionarily disabled genetic switch
10.1126/science.adp0176 · ExternalCitation · doi-reference
Synthetic Retinoids Beyond Cancer Therapy
10.1146/annurev-pharmtox-052120-104428 · ExternalCitation · doi-reference
Disparate roles of retinoid acid signaling molecules in kidney disease
10.1152/ajprenal.00045.2021 · ExternalCitation · doi-reference
Inhibition of retinoic acid signaling in proximal tubular epithelial cells protects against acute kidney injury
10.1172/jci.insight.173144 · ExternalCitation · doi-reference
Soluble RARRES1 induces podocyte apoptosis to promote glomerular disease progression
10.1172/jci140155 · ExternalCitation · doi-reference
The yin and yang of retinoic acid signaling in kidney diseases
10.1172/jci141712 · ExternalCitation · doi-reference
Extracellular vesicle therapy in neurological disorders
10.1186/s12929-024-01075-w · ExternalCitation · doi-reference
All-trans retinoic acid pretreatment of mesenchymal stem cells enhances the therapeutic effect on acute kidney injury
10.1186/s12964-024-01671-1 · ExternalCitation · doi-reference
Targeting cellular senescence in kidney diseases and aging: A focus on mesenchymal stem cells and their paracrine factors
10.1186/s12964-024-01968-1 · ExternalCitation · doi-reference
Traditional Chinese Medicine and renal regeneration: experimental evidence and future perspectives
10.1186/s13020-024-00935-9 · ExternalCitation · doi-reference
DevKidCC allows for robust classification and direct comparisons of kidney organoid datasets
10.1186/s13073-022-01023-z · ExternalCitation · doi-reference
Stem/progenitor cell in kidney: characteristics, homing, coordination, and maintenance
10.1186/s13287-021-02266-0 · ExternalCitation · doi-reference
Stem cells for treatment of liver fibrosis/cirrhosis: clinical progress and therapeutic potential
10.1186/s13287-022-03041-5 · ExternalCitation · doi-reference
All-trans retinoic acid modulates pigmentation, neuroretinal maturation, and corneal transparency in human multiocular organoids
10.1186/s13287-022-03053-1 · ExternalCitation · doi-reference
BMP7 in kidney development and disease: a multilayer regulatory network integrating inflammation, fibrosis, and regeneration
10.1186/s44505-026-00002-0 · ExternalCitation · doi-reference
Spatiotemporal manipulation of retinoic acid activity in zebrafish hindbrain development via photo-isomerization
10.1242/dev.077776 · ExternalCitation · doi-reference
Stromal cells mediate retinoid-dependent functions essential for renal development
10.1242/dev.126.6.1139 · ExternalCitation · doi-reference
Retinoic acid signaling pathways
10.1242/dev.167502 · ExternalCitation · doi-reference
Enhancing regeneration after acute kidney injury by promoting cellular dedifferentiation in zebrafish
10.1242/dmm.037390 · ExternalCitation · doi-reference
Proteinuria impairs podocyte regeneration by sequestering retinoic acid
10.1681/asn.2012090950 · ExternalCitation · doi-reference
Retinoic Acid Signaling Coordinates Macrophage-Dependent Injury and Repair after AKI
10.1681/asn.2014111108 · ExternalCitation · doi-reference
Enhancing Retinoic Acid-mediated Effects Through Inhibition of CYP26A1, CYP26B1 and HGF Signaling in Neuroblastoma Cells
10.21873/anticanres.17249 · ExternalCitation · doi-reference
Developmental biology in bioartificial tissue design: manufacturing and regulatory considerations
10.2217/rme-2017-0126 · ExternalCitation · doi-reference
The emerging role of hepatocyte growth factor in renal diseases
10.3109/10799893.2015.1080275 · ExternalCitation · doi-reference
Single-cell RNA sequencing data locate ALDH1A2-mediated retinoic acid synthetic pathway to glomerular parietal epithelial cells
10.3389/ebm.2024.10167 · ExternalCitation · doi-reference
Potential Strategies for Kidney Regeneration With Stem Cells: An Overview
10.3389/fcell.2022.892356 · ExternalCitation · doi-reference
All-Trans Retinoic Acid Attenuates Fibrotic Processes by Downregulating TGF-β1/Smad3 in Early Diabetic Nephropathy
10.3390/biom9100525 · ExternalCitation · doi-reference
Molecular Mechanisms of Renal Progenitor Regulation: How Many Pieces in the Puzzle?
10.3390/cells10010059 · ExternalCitation · doi-reference
Evolutionary Transition in the Regulation of Vertebrate Pronephros Development: A New Role for Retinoic Acid
10.3390/cells11081304 · ExternalCitation · doi-reference
Possible Underlying Mechanisms for the Renoprotective Effect of Retinoic Acid-Pretreated Wharton's Jelly Mesenchymal Stem Cells against Renal Ischemia/Reperfusion Injury
10.3390/cells11131997 · ExternalCitation · doi-reference
Gender and Renal Insufficiency: Opportunities for Their Therapeutic Management?
10.3390/cells11233820 · ExternalCitation · doi-reference
Tubule-Derived Follistatin Is Increased in the Urine of Rats with Renal Ischemia and Reflects the Severity of Acute Tubular Damage
10.3390/cells12050801 · ExternalCitation · doi-reference
How Stem and Progenitor Cells Can Affect Renal Diseases
10.3390/cells13171460 · ExternalCitation · doi-reference
Design, Synthesis, and Renal Targeting of Methylprednisolone-Lysozyme
10.3390/ijms21061922 · ExternalCitation · doi-reference
The rates of major malformations after gestational exposure to isotretinoin: a systematic review and meta-analysis
10.5468/ogs.20373 · ExternalCitation · doi-reference
WT1(+) glomerular parietal epithelial progenitors promote renal proximal tubule regeneration after severe acute kidney injury
10.7150/thno.79326 · ExternalCitation · doi-reference