Research graph
References from Streamlined CRISPR-based assays for detection and subtyping of H5 and H7 avian influenza. Local targets link to admitted publications; unresolved targets remain external evidence.
Zoonotic infections by avian influenza virus: changing global epidemiology, investigation, and control
10.1016/s1473-3099(24)00234-2 · 2024 · External reference
Characterization of a novel influenza A virus hemagglutinin subtype (H16) obtained from black-headed gulls
10.1128/jvi.79.5.2814-2822.2005 · 2005 · External reference
Deduced amino acid sequences at the haemagglutinin cleavage site of avian influenza A viruses of H5 and H7 subtypes
10.1007/bf01319010 · 1993 · External reference
Survey of the hemagglutinin (HA) cleavage site sequence of H5 and H7 avian influenza viruses: amino acid sequence at the HA cleavage site as a marker of pathogenicity potential
10.2307/1592241 · 1996 · External reference
Highly pathogenic or low pathogenic avian influenza virus subtype H7N1 infection in chicken lungs: small differences in general acute responses
10.1186/1297-9716-42-10 · 2011 · External reference
Highly pathogenic avian influenza H5N1: history, current situation, and outlook
10.1128/jvi.02209-24 · 2025 · External reference
Transmission of influenza virus in a mammalian host is increased by PB2 amino acids 627K or 627E/701N
10.1371/journal.ppat.1000252 · 2009 · External reference
Human influenza A H5N1 virus related to a highly pathogenic avian influenza virus
10.1016/s0140-6736(97)11212-0 · 1998 · External reference
Epidemiology of avian influenza A H7N9 virus in human beings across five epidemics in mainland China, 2013-17: an epidemiological study of laboratory-confirmed case series
10.1016/s1473-3099(17)30323-7 · 2017 · External reference
Pandemic preparedness through vaccine development for avian influenza viruses
10.1080/21645515.2024.2347019 · 2024 · External reference
USDA Reported H5N1 Bird Flu Detections in Poultry
2025 · External reference
The impact of H5N1 on US domestic and international dairy markets
2025 · External reference
Highly pathogenic avian influenza A(H5N1) clade 2.3.4.4b virus infection in domestic dairy cattle and cats, United States, 2024
10.3201/eid3007.240508 · 2024 · External reference
Highly pathogenic avian influenza H5N1 clade 2.3.4.4b genotype B3.13 is highly virulent for mice, rapidly causing acute pulmonary and neurologic disease
10.1038/s41467-025-60407-y · 2025 · External reference
Avian influenza virus isolation, propagation, and titration in embryonated chicken eggs
10.1007/978-1-0716-0346-8_12 · 2020 · External reference
Rapid and background-free detection of avian influenza virus in opaque sample using NIR-to-NIR upconversion nanoparticle-based lateral flow immunoassay platform
10.1016/j.bios.2018.04.047 · 2018 · External reference
Rapid, sensitive, and selective detection of H5 hemagglutinin from avian influenza virus using an immunowall device
10.1021/acsomega.9b02788 · 2019 · External reference
Development of an immunoassay for highly pathogenic avian influenza (H5N1) across diverse sample matrices
10.1021/acsnanoscienceau.4c00072 · 2025 · External reference
Toward diagnostic preparedness: detection of highly pathogenic avian influenza A(H5N1) in contrived nasal swab specimens using rapid antigen and point-of-care molecular tests
10.1128/jcm.00548-25 · 2025 · External reference
Avian influenza virus detection and quantitation by real-time RT-PCR
10.1007/978-1-0716-0346-8_11 · 2020 · External reference
Development and evaluation of a multiplex real-time RT-PCR assay for simultaneous detection of H5, H7, and H9 subtype avian influenza viruses
10.1016/j.jviromet.2024.114942 · 2024 · External reference
Complete genome sequencing of influenza A viruses using next-generation sequencing
10.1007/978-1-0716-0346-8_6 · 2020 · External reference
An evaluation of avian influenza virus whole-genome sequencing approaches using nanopore technology
10.3390/microorganisms11020529 · 2023 · External reference
Sequencing methods for HA and NA genes of avian influenza viruses from wild bird feces using Oxford Nanopore sequencing
10.1016/j.cimid.2023.102076 · 2023 · External reference
Nucleic acid detection with CRISPR-Cas13a/C2c2
10.1126/science.aam9321 · 2017 · External reference
CRISPR-Cas12a target binding unleashes indiscriminate single-stranded DNase activity
10.1126/science.aar6245 · 2018 · External reference
Rapid detection of H5 subtype avian influenza virus using CRISPR Cas13a based-lateral flow dipstick
10.3389/fmicb.2023.1283210 · 2023 · External reference
CRISPR-Cas13a-based detection method for avian influenza virus
10.3389/fmicb.2023.1288951 · 2023 · External reference
Based on CRISPR-Cas13a system, to establish a rapid visual detection method for avian influenza viruses
2023 · External reference
Rapid detection of avian influenza virus based on CRISPR-Cas12a
10.1186/s12985-023-02232-7 · 2023 · External reference
CRISPR/Cas13a-based genome editing for establishing the detection method of H9N2 subtype avian influenza virus
10.1016/j.psj.2024.104068 · 2024 · External reference
On-site and visual detection of the H5 subtype avian influenza virus based on RT-RPA and CRISPR/Cas12a
10.3390/v16050753 · 2024 · External reference
Rapid and specific on-site H5Nx avian influenza diagnosis via RPA and PAM-independent CRISPR-Cas12a assay combined with anti-NP antibody-based viral RNA purification
10.3389/fvets.2025.1520349 · 2025 · External reference
Rapid detection of Pan-Avian Influenza Virus and H5, H7, H9 subtypes of Avian Influenza Virus using CRISPR/Cas13a and lateral flow assay
2025 · External reference
Streamlined inactivation, amplification, and Cas13-based detection of SARS-CoV-2
10.1038/s41467-020-19097-x · 2020 · External reference
Simplified Cas13-based assays for the fast identification of SARS-CoV-2 and its variants
10.1038/s41551-022-00889-z · 2022 · External reference
CRISPR-based assays for point-of-need detection and subtyping of influenza
10.1016/j.jmoldx.2024.04.004 · 2024 · External reference
Designing sensitive viral diagnostics with machine learning
10.1038/s41587-022-01213-5 · 2022 · External reference
Strategies to improve multi-enzyme compatibility and coordination in one-pot SHERLOCK
10.1021/acs.analchem.2c05032 · 2023 · External reference
Avian influenza
2025 · External reference
Multiplex Real-Time Reverse Transcription PCR for Influenza A Virus, Influenza B Virus, and Severe Acute Respiratory Syndrome Coronavirus 2
10.3201/eid2707.210462 · 2021 · External reference
Validation of H5 influenza virus subtyping RT-qPCR assay and low prevalence of H5 detection in 2024-2025 influenza virus season
10.1128/jcm.00415-25 · 2025 · External reference
Model-directed generation of artificial CRISPR-Cas13a guide RNA sequences improves nucleic acid detection
10.1038/s41587-024-02422-w · 2025 · External reference
Evaluation of replication and pathogenicity of avian influenza a H7 subtype viruses in a mouse model
10.1128/jvi.00970-07 · 2007 · External reference
Risk assessment of the newly emerged H7N9 avian influenza viruses
10.1080/22221751.2023.2172965 · 2023 · External reference
Factors associated with fatality due to avian influenza A(H7N9) infection in China
10.1093/cid/ciz779 · 2020 · External reference
Comparative assessment of lyophilized and wet reagents for the molecular detection of H5N1 high pathogenic avian influenza virus and H9N2 low pathogenic avian influenza virus
10.1016/j.jviromet.2023.114686 · 2023 · External reference
MAFFT online service: multiple sequence alignment, interactive sequence choice and visualization
10.1093/bib/bbx108 · 2019 · External reference
Detection of hemagglutinin H5 influenza A virus sequence in municipal wastewater solids at wastewater treatment plants with increases in influenza A in spring, 2024
10.1021/acs.estlett.4c00331 · 2024 · External reference
FastTree: computing large minimum evolution trees with profiles instead of a distance matrix
10.1093/molbev/msp077 · 2009 · External reference
ETE 3: Reconstruction, analysis, and visualization of phylogenomic data
10.1093/molbev/msw046 · 2016 · External reference
Avian influenza virus detection and quantitation by real-time RT-PCR
10.1007/978-1-0716-0346-8_11 · ExternalCitation · doi-reference
Avian influenza virus isolation, propagation, and titration in embryonated chicken eggs
10.1007/978-1-0716-0346-8_12 · ExternalCitation · doi-reference
Complete genome sequencing of influenza A viruses using next-generation sequencing
10.1007/978-1-0716-0346-8_6 · ExternalCitation · doi-reference
Deduced amino acid sequences at the haemagglutinin cleavage site of avian influenza A viruses of H5 and H7 subtypes
10.1007/bf01319010 · ExternalCitation · doi-reference
Rapid and background-free detection of avian influenza virus in opaque sample using NIR-to-NIR upconversion nanoparticle-based lateral flow immunoassay platform
10.1016/j.bios.2018.04.047 · ExternalCitation · doi-reference
Sequencing methods for HA and NA genes of avian influenza viruses from wild bird feces using Oxford Nanopore sequencing
10.1016/j.cimid.2023.102076 · ExternalCitation · doi-reference
CRISPR-based assays for point-of-need detection and subtyping of influenza
10.1016/j.jmoldx.2024.04.004 · ExternalCitation · doi-reference
Comparative assessment of lyophilized and wet reagents for the molecular detection of H5N1 high pathogenic avian influenza virus and H9N2 low pathogenic avian influenza virus
10.1016/j.jviromet.2023.114686 · ExternalCitation · doi-reference
Development and evaluation of a multiplex real-time RT-PCR assay for simultaneous detection of H5, H7, and H9 subtype avian influenza viruses
10.1016/j.jviromet.2024.114942 · ExternalCitation · doi-reference
CRISPR/Cas13a-based genome editing for establishing the detection method of H9N2 subtype avian influenza virus
10.1016/j.psj.2024.104068 · ExternalCitation · doi-reference
Human influenza A H5N1 virus related to a highly pathogenic avian influenza virus
10.1016/s0140-6736(97)11212-0 · ExternalCitation · doi-reference
Epidemiology of avian influenza A H7N9 virus in human beings across five epidemics in mainland China, 2013-17: an epidemiological study of laboratory-confirmed case series
10.1016/s1473-3099(17)30323-7 · ExternalCitation · doi-reference
Zoonotic infections by avian influenza virus: changing global epidemiology, investigation, and control
10.1016/s1473-3099(24)00234-2 · ExternalCitation · doi-reference
Strategies to improve multi-enzyme compatibility and coordination in one-pot SHERLOCK
10.1021/acs.analchem.2c05032 · ExternalCitation · doi-reference
Detection of hemagglutinin H5 influenza A virus sequence in municipal wastewater solids at wastewater treatment plants with increases in influenza A in spring, 2024
10.1021/acs.estlett.4c00331 · ExternalCitation · doi-reference
Development of an immunoassay for highly pathogenic avian influenza (H5N1) across diverse sample matrices
10.1021/acsnanoscienceau.4c00072 · ExternalCitation · doi-reference
Rapid, sensitive, and selective detection of H5 hemagglutinin from avian influenza virus using an immunowall device
10.1021/acsomega.9b02788 · ExternalCitation · doi-reference
Streamlined inactivation, amplification, and Cas13-based detection of SARS-CoV-2
10.1038/s41467-020-19097-x · ExternalCitation · doi-reference
Highly pathogenic avian influenza H5N1 clade 2.3.4.4b genotype B3.13 is highly virulent for mice, rapidly causing acute pulmonary and neurologic disease
10.1038/s41467-025-60407-y · ExternalCitation · doi-reference
Simplified Cas13-based assays for the fast identification of SARS-CoV-2 and its variants
10.1038/s41551-022-00889-z · ExternalCitation · doi-reference
Designing sensitive viral diagnostics with machine learning
10.1038/s41587-022-01213-5 · ExternalCitation · doi-reference
Model-directed generation of artificial CRISPR-Cas13a guide RNA sequences improves nucleic acid detection
10.1038/s41587-024-02422-w · ExternalCitation · doi-reference
Pandemic preparedness through vaccine development for avian influenza viruses
10.1080/21645515.2024.2347019 · ExternalCitation · doi-reference
Risk assessment of the newly emerged H7N9 avian influenza viruses
10.1080/22221751.2023.2172965 · ExternalCitation · doi-reference
MAFFT online service: multiple sequence alignment, interactive sequence choice and visualization
10.1093/bib/bbx108 · ExternalCitation · doi-reference
Factors associated with fatality due to avian influenza A(H7N9) infection in China
10.1093/cid/ciz779 · ExternalCitation · doi-reference
FastTree: computing large minimum evolution trees with profiles instead of a distance matrix
10.1093/molbev/msp077 · ExternalCitation · doi-reference
ETE 3: Reconstruction, analysis, and visualization of phylogenomic data
10.1093/molbev/msw046 · ExternalCitation · doi-reference
Nucleic acid detection with CRISPR-Cas13a/C2c2
10.1126/science.aam9321 · ExternalCitation · doi-reference
CRISPR-Cas12a target binding unleashes indiscriminate single-stranded DNase activity
10.1126/science.aar6245 · ExternalCitation · doi-reference
Validation of H5 influenza virus subtyping RT-qPCR assay and low prevalence of H5 detection in 2024-2025 influenza virus season
10.1128/jcm.00415-25 · ExternalCitation · doi-reference
Toward diagnostic preparedness: detection of highly pathogenic avian influenza A(H5N1) in contrived nasal swab specimens using rapid antigen and point-of-care molecular tests
10.1128/jcm.00548-25 · ExternalCitation · doi-reference
Evaluation of replication and pathogenicity of avian influenza a H7 subtype viruses in a mouse model
10.1128/jvi.00970-07 · ExternalCitation · doi-reference
Highly pathogenic avian influenza H5N1: history, current situation, and outlook
10.1128/jvi.02209-24 · ExternalCitation · doi-reference
Characterization of a novel influenza A virus hemagglutinin subtype (H16) obtained from black-headed gulls
10.1128/jvi.79.5.2814-2822.2005 · ExternalCitation · doi-reference
Highly pathogenic or low pathogenic avian influenza virus subtype H7N1 infection in chicken lungs: small differences in general acute responses
10.1186/1297-9716-42-10 · ExternalCitation · doi-reference
Rapid detection of avian influenza virus based on CRISPR-Cas12a
10.1186/s12985-023-02232-7 · ExternalCitation · doi-reference
Transmission of influenza virus in a mammalian host is increased by PB2 amino acids 627K or 627E/701N
10.1371/journal.ppat.1000252 · ExternalCitation · doi-reference
Survey of the hemagglutinin (HA) cleavage site sequence of H5 and H7 avian influenza viruses: amino acid sequence at the HA cleavage site as a marker of pathogenicity potential
10.2307/1592241 · ExternalCitation · doi-reference
Multiplex Real-Time Reverse Transcription PCR for Influenza A Virus, Influenza B Virus, and Severe Acute Respiratory Syndrome Coronavirus 2
10.3201/eid2707.210462 · ExternalCitation · doi-reference
Highly pathogenic avian influenza A(H5N1) clade 2.3.4.4b virus infection in domestic dairy cattle and cats, United States, 2024
10.3201/eid3007.240508 · ExternalCitation · doi-reference
Rapid detection of H5 subtype avian influenza virus using CRISPR Cas13a based-lateral flow dipstick
10.3389/fmicb.2023.1283210 · ExternalCitation · doi-reference
CRISPR-Cas13a-based detection method for avian influenza virus
10.3389/fmicb.2023.1288951 · ExternalCitation · doi-reference
Rapid and specific on-site H5Nx avian influenza diagnosis via RPA and PAM-independent CRISPR-Cas12a assay combined with anti-NP antibody-based viral RNA purification
10.3389/fvets.2025.1520349 · ExternalCitation · doi-reference
An evaluation of avian influenza virus whole-genome sequencing approaches using nanopore technology
10.3390/microorganisms11020529 · ExternalCitation · doi-reference
On-site and visual detection of the H5 subtype avian influenza virus based on RT-RPA and CRISPR/Cas12a
10.3390/v16050753 · ExternalCitation · doi-reference
