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References from Decomposition-driven biomarker identification enhances non-invasive early cancer detection. Local targets link to admitted publications; unresolved targets remain external evidence.
Circulating cell-free DNA-based multi-cancer early detection
10.1016/j.trecan.2023.08.010 · 2024 · External reference
EpiPanGI Dx: A Cell-free DNA Methylation Fingerprint for the Early Detection of Gastrointestinal Cancers
10.1158/1078-0432.ccr-21-1982 · 2021 · External reference
Unintrusive multi-cancer detection by circulating cell-free DNA methylation sequencing (THUNDER): development and independent validation studies
10.1016/j.annonc.2023.02.010 · 2023 · External reference
Sensitive and specific multi-cancer detection and localization using methylation signatures in cell-free DNA
10.1016/j.annonc.2020.02.011 · 2020 · External reference
Cost-effective methylome sequencing of cell-free DNA for accurately detecting and locating cancer
10.1038/s41467-022-32995-6 · 2022 · External reference
GUIDE: a prospective cohort study for blood-based early detection of gastrointestinal cancers using targeted DNA methylation and fragmentomics sequencing
10.1186/s12943-025-02367-x · 2025 · External reference
Intratumoral heterogeneity and drug resistance in cancer
10.1186/s12935-025-03734-w · 2025 · External reference
Cell-of-Origin Patterns Dominate the Molecular Classification of 10,000 Tumors from 33 Types of Cancer
10.1016/j.cell.2018.03.022 · 2018 · External reference
The evolving tumor microenvironment: From cancer initiation to metastatic outgrowth
10.1016/j.ccell.2023.02.016 · 2023 · External reference
The role of tumor microenvironment in cholangiocarcinoma
2023 · External reference
Unresolved reference
2022 · External reference
The changing face of circulating tumor DNA (ctDNA) profiling: Factors that shape the landscape of methodologies, technologies, and commercialization
2023 · External reference
Single-cell multiomics sequencing and analyses of human colorectal cancer
10.1126/science.aao3791 · 2018 · External reference
A DNA methylation atlas of normal human cell types
10.1038/s41586-022-05580-6 · 2023 · External reference
Pan-cancer deconvolution of tumour composition using DNA methylation
10.1038/s41467-018-05570-1 · 2018 · External reference
MethylResolver-a method for deconvoluting bulk DNA methylation profiles into known and unknown cell contents
10.1038/s42003-020-01146-2 · 2020 · External reference
HiTIMED: hierarchical tumor immune microenvironment epigenetic deconvolution for accurate cell type resolution in the tumor microenvironment using tumor-type-specific DNA methylation data
10.1186/s12967-022-03736-6 · 2022 · External reference
Reference-free deconvolution of DNA methylation data and mediation by cell composition effects
10.1186/s12859-016-1140-4 · 2016 · External reference
MeDeCom: discovery and quantification of latent components of heterogeneous methylomes
10.1186/s13059-017-1182-6 · 2017 · External reference
Non-invasive early detection of cancer four years before conventional diagnosis using a blood test
10.1038/s41467-020-17316-z · 2020 · External reference
CFEA: a cell-free epigenome atlas in human diseases
10.1093/nar/gkz715 · 2020 · External reference
Terminal modifications independent cell-free RNA sequencing enables sensitive early cancer detection and classification
10.1038/s41467-023-44461-y · 2024 · External reference
Unsupervised detection of fragment length signatures of circulating tumor DNA using non-negative matrix factorization
10.7554/elife.71569 · 2022 · External reference
A Landscape of Pharmacogenomic Interactions in Cancer
10.1016/j.cell.2016.06.017 · 2016 · External reference
WebGestalt 2024: faster gene set analysis and new support for metabolomics and multi-omics
10.1093/nar/gkae456 · 2024 · External reference
