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References from Structures of multiple states of the nicotinamide nucleotide transhydrogenase from Escherichia coli. Local targets link to admitted publications; unresolved targets remain external evidence.
Unresolved reference
2018 · External reference
Proton translocation by transhydrogenase
10.1016/s0014-5793(03)01123-2 · 2003 · External reference
Review and Hypothesis. New insights into the reaction mechanism of transhydrogenase: Swivelling the dIII component may gate the proton channel
10.1016/j.febslet.2015.06.027 · 2015 · External reference
Energy-linked nicotinamide nucleotide transhydrogenases
10.1016/0304-4173(77)90007-6 · 1977 · External reference
The soluble and membrane-bound transhydrogenases UdhA and PntAB have divergent functions in NADPH metabolism of Escherichia coli
10.1074/jbc.m311657200 · 2004 · External reference
Mitochondrial NAD(P)+ transhydrogenase: From molecular features to physiology and disease
10.1089/ars.2021.0111 · 2022 · External reference
Nicotinamide nucleotide transhydrogenase is required for brain mitochondrial redox balance under hampered energy substrate metabolism and high-fat diet
10.1111/jnc.14602 · 2018 · External reference
Coenzyme Q10 and nicotinamide nucleotide transhydrogenase: Sentinels for mitochondrial hydrogen peroxide signaling
10.1016/j.freeradbiomed.2023.08.015 · 2023 · External reference
Nicotinamide nucleotide transhydrogenase regulates mitochondrial metabolism in NSCLC through maintenance of Fe-S protein function
10.1084/jem.20191689 · 2020 · External reference
Nicotinamide nucleotide transhydrogenase-mediated redox homeostasis promotes tumor growth and metastasis in gastric cancer
10.1016/j.redox.2018.07.017 · 2018 · External reference
Regulation of immune cell function by nicotinamide nucleotide transhydrogenase
10.1152/ajpcell.00607.2020 · 2022 · External reference
Nicotinamide nucleotide transhydrogenase Is essential for adrenal steroidogenesis: Clinical and In vitro lessons
10.1210/clinem/dgac705 · 2023 · External reference
IL-1β-associated NNT acetylation orchestrates iron-sulfur cluster maintenance and cancer immunotherapy resistance
10.1016/j.molcel.2023.05.011 · 2023 · External reference
Uncovering the IL-1beta-PCAF-NNT axis: A new player in ferroptosis and tumor immune evasion
10.1002/cac2.12473 · 2023 · External reference
Reverse reaction of nicotinamide nucleotide transhydrogenase promotes ROS production and contributes to right ventricular failure
10.1016/j.jacbts.2022.03.015 · 2022 · External reference
CRISPR-based DNA methylation editing of NNT rescues the cisplatin resistance of lung cancer cells by reducing autophagy
10.1007/s00204-022-03404-0 · 2023 · External reference
Structural biology. Division of labor in transhydrogenase by alternating proton translocation and hydride transfer
10.1126/science.1260451 · 2015 · External reference
Structures of the dI2dIII1 complex of proton-translocating transhydrogenase with bound, inactive analogues of NADH and NADPH reveal active site geometries
10.1021/bi061843r · 2007 · External reference
Protein-protein recognition, hydride transfer and proton pumping in the transhydrogenase complex
10.1016/s0969-2126(00)00171-4 · 2000 · External reference
The crystal structure of an asymmetric complex of the two nucleotide binding components of proton-translocating transhydrogenase
10.1016/s0969-2126(01)00571-8 · 2001 · External reference
X-ray structure of domain I of the proton-pumping membrane protein transhydrogenase from Escherichia coli
10.1016/j.jmb.2005.07.022 · 2005 · External reference
Active-site conformational changes associated with hydride transfer in proton-translocating transhydrogenase
10.1021/bi0497594 · 2004 · External reference
Critical role of water molecules in proton translocation by the membrane-bound transhydrogenase
10.1016/j.str.2017.05.022 · 2017 · External reference
Crystal structures of transhydrogenase domain I with and without bound NADH
10.1021/bi020251f · 2002 · External reference
Interactions between transhydrogenase and thio-nicotinamide analogues of NAD(H) and NADP(H) underline the importance of nucleotide conformational changes in coupling to proton translocation
10.1074/jbc.m303061200 · 2003 · External reference
Conformational diversity in NAD(H) and interacting transhydrogenase nicotinamide nucleotide binding domains
10.1016/j.jmb.2004.11.070 · 2005 · External reference
Proton-translocating nicotinamide nucleotide transhydrogenase: A structural perspective
10.3389/fphys.2017.01089 · 2017 · External reference
Evidence that the transfer of hydride ion equivalents between nucleotides by proton-translocating transhydrogenase is direct
10.1074/jbc.272.44.27535 · 1997 · External reference
Kinetic resolution of the reaction catalyzed by proton-translocating transhydrogenase from Escherichia coli as revealed by experiments with analogs of the nucleotide substrates
10.1111/j.1432-1033.1994.tb18587.x · 1994 · External reference
Structure and mechanism of mitochondrial proton-translocating transhydrogenase
10.1038/s41586-019-1519-2 · 2019 · External reference
Interactions of the NADP(H)-binding domain III of proton-translocating transhydrogenase from Escherichia coli with NADP(H) and the NAD(H)-binding domain I studied by NMR and site-directed mutagenesis
10.1021/bi0004091 · 2000 · External reference
Site-specific inhibitors of mitochondrial nicotinamide-nucleotide transhydrogenase
10.1111/j.1432-1033.1972.tb02557.x · 1972 · External reference
Inhibition of mitochondrial nicotinamide nucleotide transhydrogenase by CoA-thioesters of long-chain fatty acids
10.1016/0006-291x(71)90175-6 · 1971 · External reference
Features and development of Coot
10.1107/s0907444910007493 · 2010 · External reference
Mitochondrial energy-linked nicotinamide nucleotide transhydrogenase: effect of substrates on the sensitivity of the enzyme to trypsin and identification of tryptic cleavage sites
10.1021/bi00469a017 · 1990 · External reference
Mitochondrial nicotinamide nucleotide transhydrogenase: NADPH binding increases and NADP binding decreases the acidity and susceptibility to modification of cysteine-893
10.1021/bi00440a049 · 1989 · External reference
10.1016/j.csbj.2022.09.036 · 2022 · Admitted local publication
Purification of a recombinant membrane protein tagged with a calmodulin-binding domain: properties of chimeras of the Escherichia coli nicotinamide nucleotide transhydrogenase and the C-terminus of human plasma membrane Ca2+ -ATPase
10.1016/j.pep.2004.03.002 · 2004 · External reference
Automated electron microscope tomography using robust prediction of specimen movements
10.1016/j.jsb.2005.07.007 · 2005 · External reference
MotionCor2: anisotropic correction of beam-induced motion for improved cryo-electron microscopy
10.1038/nmeth.4193 · 2017 · External reference
Gctf: Real-time CTF determination and correction
10.1016/j.jsb.2015.11.003 · 2016 · External reference
RELION: implementation of a Bayesian approach to cryo-EM structure determination
10.1016/j.jsb.2012.09.006 · 2012 · External reference
cryoSPARC: algorithms for rapid unsupervised cryo-EM structure determination
10.1038/nmeth.4169 · 2017 · External reference
UCSF Chimera--a visualization system for exploratory research and analysis
10.1002/jcc.20084 · 2004 · External reference
Highly accurate protein structure prediction with AlphaFold
10.1038/s41586-021-03819-2 · 2021 · External reference
MOLEonline: a web-based tool for analyzing channels, tunnels and pores (2018 update)
10.1093/nar/gky309 · 2018 · External reference
UCSF ChimeraX: Meeting modern challenges in visualization and analysis
10.1002/pro.3235 · 2018 · External reference
Energy transfer between the nicotinamide nucleotide transhydrogenase and ATP synthase of Escherichia coli
10.1038/s41598-021-00651-6 · 2021 · External reference
