Research graph
References from Markers of Autonomic Function and Cancer Mortality Risk in Healthy Adults. Local targets link to admitted publications; unresolved targets remain external evidence.
Research opportunities in autonomic neural mechanisms of cardiopulmonary regulation: a report from the national heart, lung, and blood institute and the national institutes of health office of the director workshop
10.1016/j.jacbts.2021.11.003 · 2022 · External reference
Autonomic interactions in cardiac control
10.1111/j.1749-6632.1990.tb37302.x · 1990 · External reference
Heart-rate recovery immediately after exercise as a predictor of mortality
10.1056/nejm199910283411804 · 1999 · External reference
Heart-rate profile during exercise as a predictor of sudden death
10.1056/nejmoa043012 · 2005 · External reference
Protective role of resting heart rate on all-cause and cardiovascular disease mortality
10.1016/j.mayocp.2013.09.011 · 2013 · External reference
Heart rate recovery and risk of cardiovascular events and all-cause mortality: a meta-analysis of prospective cohort studies
10.1161/jaha.117.005505 · 2017 · External reference
Relation of heart rate parameters during exercise test to sudden death and all-cause mortality in asymptomatic men
10.1016/j.amjcard.2008.01.021 · 2008 · External reference
Resting heart rate and risk of cancer mortality
10.1158/1055-9965.epi-20-1731 · 2021 · External reference
Resting heart rate as a predictor of cancer mortality: a systematic review and meta-analysis
10.3390/jcm10071354 · 2021 · External reference
Resting heart rate, temporal changes in resting heart rate, and overall and cause-specific mortality
10.1136/heartjnl-2017-312251 · 2018 · External reference
Resting heart rate and the risk of cardiovascular disease, total cancer, and all-cause mortality - a systematic review and dose-response meta-analysis of prospective studies
10.1016/j.numecd.2017.04.004 · 2017 · External reference
Heart rate and risk of cancer death in healthy men
10.1371/journal.pone.0021310 · 2011 · External reference
Molecular pathways: beta-adrenergic signaling in cancer
10.1158/1078-0432.ccr-11-0641 · 2012 · External reference
Cardiorespiratory fitness and mortality from all causes, cardiovascular disease and cancer: dose-response meta-analysis of cohort studies
10.1136/bjsports-2021-104876 · 2022 · External reference
Cardiorespiratory fitness as predictor of cancer mortality: a systematic review and meta-analysis
10.1093/annonc/mdu250 · 2015 · External reference
Elevated resting heart rate, physical fitness and all-cause mortality: a 16-year follow-up in the Copenhagen male study
10.1136/heartjnl-2012-303375 · 2013 · External reference
Physical fitness as a predictor of mortality among healthy, middle-aged Norwegian men
10.1056/nejm199302253280803 · 1993 · External reference
The association between midlife cardiorespiratory fitness levels and later-life dementia: a cohort study
10.7326/0003-4819-158-3-201302050-00005 · 2013 · External reference
Association of all-cause and cardiovascular mortality with high levels of physical activity and concurrent coronary artery calcification
10.1001/jamacardio.2018.4628 · 2019 · External reference
Autonomic function and prognosis
10.3949/ccjm.76.s2.04 · 2009 · External reference
Impaired chronotropic response to exercise stress testing as a predictor of mortality
10.1001/jama.281.6.524 · 1999 · External reference
Autonomic dysfunction among adult survivors of childhood cancer in the St. Jude lifetime cohort study
10.1016/j.jaccao.2024.08.005 · 2024 · External reference
Secular change in cardiorespiratory fitness of men: Cooper center longitudinal study
10.1249/mss.0b013e31821c00a7 · 2011 · External reference
Physical fitness and all-cause mortality. A prospective study of healthy men and women
10.1001/jama.1989.03430170057028 · 1989 · External reference
Higher omega-3 index is associated with more rapid heart rate recovery in healthy men and women
10.1016/j.plefa.2020.102206 · 2020 · External reference
Changes in physical fitness and all-cause mortality. A prospective study of healthy and unhealthy men
10.1001/jama.1995.03520380029031 · 1995 · External reference
Unresolved reference
2013 · External reference
A comparative analysis of four protocols for maximal treadmill stress testing
10.1016/s0002-8703(76)80401-2 · 1976 · External reference
Comparative analysis of physiologic responses to three different maximal graded exercise test protocols in healthy women
10.1016/0002-8703(82)90275-7 · 1982 · External reference
Midlife cardiorespiratory fitness, incident cancer, and survival after cancer in men: the cooper center longitudinal study
10.1001/jamaoncol.2015.0226 · 2015 · External reference
Why you should avoid using multiple fine–gray models: insights from (attempts at) simulating proportional subdistribution hazards data
10.1093/jrsssa/qnae056 · 2024 · External reference
Inference and missing data
10.1093/biomet/63.3.581 · 1976 · External reference
Deciphering death: a commentary on Gompertz (1825) 'On the nature of the function expressive of the law of human mortality, and on a new mode of determining the value of life contingencies'
10.1098/rstb.2014.0379 · 2015 · External reference
How do we age? A decomposition of Gompertz law
10.1016/j.jhealeco.2025.102988 · 2025 · External reference
Cardiovascular autonomic dysfunction in patients with cancer
10.1007/s11886-018-1010-y · 2018 · External reference
Elevated resting heart rate is an independent risk factor for mortality in patients with colorectal cancer: a retrospective cohort study
10.1158/1055-9965.epi-25-0704 · 2025 · External reference
Resting heart rate is an independent predictor of death in patients with colorectal, pancreatic, and non-small cell lung cancer: results of a prospective cardiovascular long-term study
10.1002/ejhf.670 · 2016 · External reference
Increased resting heart rate and prognosis in treatment-naive unselected cancer patients: results from a prospective observational study
10.1002/ejhf.1782 · 2020 · External reference
Systolic blood pressure response during exercise stress testing: the henry Ford ExercIse Testing (FIT) project
10.1161/jaha.115.002050 · 2015 · External reference
Relations of exercise blood pressure response to cardiovascular risk factors and vascular function in the Framingham heart study
10.1161/circulationaha.111.063933 · 2012 · External reference
Blood pressure responses during exercise: physiological correlates and clinical implications
10.1161/atvbaha.122.318512 · 2023 · External reference
The relationship between resting heart rate and all-cause, cardiovascular and cancer mortality
10.1093/oxfordjournals.eurheartj.a015465 · 1997 · External reference
Heart rate and mortality
10.1046/j.1365-2796.2000.00602.x · 2000 · External reference
Sleep disturbance in association with elevated pulse rate for prediction of mortality--consequences of mental strain?
10.1046/j.1365-2796.2001.00913.x · 2001 · External reference
Vasomotor symptoms of menopause, autonomic dysfunction, and cardiovascular disease
10.1152/ajpheart.00477.2022 · 2022 · External reference
Autonomic nervous system dysfunction: JACC focus seminar
10.1016/j.jacc.2018.12.064 · 2019 · External reference
Cancer and cardiovascular disease: shared risk factors, mechanisms, and clinical implications: JACC: cardiooncology state-of-the-art review
10.1016/j.jaccao.2025.07.001 · 2025 · External reference
Cardiovascular risk factors are associated with future cancer
10.1016/j.jaccao.2020.12.003 · 2021 · External reference
Resting heart rate as a prognostic factor for mortality in patients with breast cancer
10.1007/s10549-016-3938-1 · 2016 · External reference
Heart rate recovery: autonomic determinants, methods of assessment and association with mortality and cardiovascular diseases
10.1111/cpf.12102 · 2014 · External reference
Heart rate response and recovery in cycle exercise testing: normal values and association with mortality
10.1093/eurjpc/zwae308 · 2025 · External reference
Consumer wearable health and fitness technology in cardiovascular medicine: JACC state-of-the-art review
10.1016/j.jacc.2023.04.054 · 2023 · External reference
Smart wearable devices in cardiovascular care: where we are and how to move forward
10.1038/s41569-021-00522-7 · 2021 · External reference
Autonomic dysfunction in early breast cancer: incidence, clinical importance, and underlying mechanisms
10.1016/j.ahj.2015.05.014 · 2015 · External reference
Autonomic dysfunction among adult survivors of childhood cancer
10.1016/j.jaccao.2024.09.004 · 2024 · External reference
Electrodiagnostic assessment of the autonomic nervous system: a consensus statement endorsed by the American Autonomic Society, American Academy of Neurology, and the International Federation of Clinical Neurophysiology
10.1016/j.clinph.2020.11.024 · 2021 · External reference
Physical fitness and all-cause mortality. A prospective study of healthy men and women
10.1001/jama.1989.03430170057028 · ExternalCitation · doi-reference
Changes in physical fitness and all-cause mortality. A prospective study of healthy and unhealthy men
10.1001/jama.1995.03520380029031 · ExternalCitation · doi-reference
Impaired chronotropic response to exercise stress testing as a predictor of mortality
10.1001/jama.281.6.524 · ExternalCitation · doi-reference
Association of all-cause and cardiovascular mortality with high levels of physical activity and concurrent coronary artery calcification
10.1001/jamacardio.2018.4628 · ExternalCitation · doi-reference
Midlife cardiorespiratory fitness, incident cancer, and survival after cancer in men: the cooper center longitudinal study
10.1001/jamaoncol.2015.0226 · ExternalCitation · doi-reference
Increased resting heart rate and prognosis in treatment-naive unselected cancer patients: results from a prospective observational study
10.1002/ejhf.1782 · ExternalCitation · doi-reference
Resting heart rate is an independent predictor of death in patients with colorectal, pancreatic, and non-small cell lung cancer: results of a prospective cardiovascular long-term study
10.1002/ejhf.670 · ExternalCitation · doi-reference
Resting heart rate as a prognostic factor for mortality in patients with breast cancer
10.1007/s10549-016-3938-1 · ExternalCitation · doi-reference
Cardiovascular autonomic dysfunction in patients with cancer
10.1007/s11886-018-1010-y · ExternalCitation · doi-reference
Comparative analysis of physiologic responses to three different maximal graded exercise test protocols in healthy women
10.1016/0002-8703(82)90275-7 · ExternalCitation · doi-reference
Autonomic dysfunction in early breast cancer: incidence, clinical importance, and underlying mechanisms
10.1016/j.ahj.2015.05.014 · ExternalCitation · doi-reference
Relation of heart rate parameters during exercise test to sudden death and all-cause mortality in asymptomatic men
10.1016/j.amjcard.2008.01.021 · ExternalCitation · doi-reference
Electrodiagnostic assessment of the autonomic nervous system: a consensus statement endorsed by the American Autonomic Society, American Academy of Neurology, and the International Federation of Clinical Neurophysiology
10.1016/j.clinph.2020.11.024 · ExternalCitation · doi-reference
Research opportunities in autonomic neural mechanisms of cardiopulmonary regulation: a report from the national heart, lung, and blood institute and the national institutes of health office of the director workshop
10.1016/j.jacbts.2021.11.003 · ExternalCitation · doi-reference
Autonomic nervous system dysfunction: JACC focus seminar
10.1016/j.jacc.2018.12.064 · ExternalCitation · doi-reference
Consumer wearable health and fitness technology in cardiovascular medicine: JACC state-of-the-art review
10.1016/j.jacc.2023.04.054 · ExternalCitation · doi-reference
Cardiovascular risk factors are associated with future cancer
10.1016/j.jaccao.2020.12.003 · ExternalCitation · doi-reference
Autonomic dysfunction among adult survivors of childhood cancer in the St. Jude lifetime cohort study
10.1016/j.jaccao.2024.08.005 · ExternalCitation · doi-reference
Autonomic dysfunction among adult survivors of childhood cancer
10.1016/j.jaccao.2024.09.004 · ExternalCitation · doi-reference
Cancer and cardiovascular disease: shared risk factors, mechanisms, and clinical implications: JACC: cardiooncology state-of-the-art review
10.1016/j.jaccao.2025.07.001 · ExternalCitation · doi-reference
How do we age? A decomposition of Gompertz law
10.1016/j.jhealeco.2025.102988 · ExternalCitation · doi-reference
Protective role of resting heart rate on all-cause and cardiovascular disease mortality
10.1016/j.mayocp.2013.09.011 · ExternalCitation · doi-reference
Resting heart rate and the risk of cardiovascular disease, total cancer, and all-cause mortality - a systematic review and dose-response meta-analysis of prospective studies
10.1016/j.numecd.2017.04.004 · ExternalCitation · doi-reference
Higher omega-3 index is associated with more rapid heart rate recovery in healthy men and women
10.1016/j.plefa.2020.102206 · ExternalCitation · doi-reference
A comparative analysis of four protocols for maximal treadmill stress testing
10.1016/s0002-8703(76)80401-2 · ExternalCitation · doi-reference
Smart wearable devices in cardiovascular care: where we are and how to move forward
10.1038/s41569-021-00522-7 · ExternalCitation · doi-reference
Heart rate and mortality
10.1046/j.1365-2796.2000.00602.x · ExternalCitation · doi-reference
Sleep disturbance in association with elevated pulse rate for prediction of mortality--consequences of mental strain?
10.1046/j.1365-2796.2001.00913.x · ExternalCitation · doi-reference
Physical fitness as a predictor of mortality among healthy, middle-aged Norwegian men
10.1056/nejm199302253280803 · ExternalCitation · doi-reference
Heart-rate recovery immediately after exercise as a predictor of mortality
10.1056/nejm199910283411804 · ExternalCitation · doi-reference
Heart-rate profile during exercise as a predictor of sudden death
10.1056/nejmoa043012 · ExternalCitation · doi-reference
Cardiorespiratory fitness as predictor of cancer mortality: a systematic review and meta-analysis
10.1093/annonc/mdu250 · ExternalCitation · doi-reference
Inference and missing data
10.1093/biomet/63.3.581 · ExternalCitation · doi-reference
Heart rate response and recovery in cycle exercise testing: normal values and association with mortality
10.1093/eurjpc/zwae308 · ExternalCitation · doi-reference
Why you should avoid using multiple fine–gray models: insights from (attempts at) simulating proportional subdistribution hazards data
10.1093/jrsssa/qnae056 · ExternalCitation · doi-reference
The relationship between resting heart rate and all-cause, cardiovascular and cancer mortality
10.1093/oxfordjournals.eurheartj.a015465 · ExternalCitation · doi-reference
Deciphering death: a commentary on Gompertz (1825) 'On the nature of the function expressive of the law of human mortality, and on a new mode of determining the value of life contingencies'
10.1098/rstb.2014.0379 · ExternalCitation · doi-reference
Heart rate recovery: autonomic determinants, methods of assessment and association with mortality and cardiovascular diseases
10.1111/cpf.12102 · ExternalCitation · doi-reference
Autonomic interactions in cardiac control
10.1111/j.1749-6632.1990.tb37302.x · ExternalCitation · doi-reference
Cardiorespiratory fitness and mortality from all causes, cardiovascular disease and cancer: dose-response meta-analysis of cohort studies
10.1136/bjsports-2021-104876 · ExternalCitation · doi-reference
Elevated resting heart rate, physical fitness and all-cause mortality: a 16-year follow-up in the Copenhagen male study
10.1136/heartjnl-2012-303375 · ExternalCitation · doi-reference
Resting heart rate, temporal changes in resting heart rate, and overall and cause-specific mortality
10.1136/heartjnl-2017-312251 · ExternalCitation · doi-reference
Vasomotor symptoms of menopause, autonomic dysfunction, and cardiovascular disease
10.1152/ajpheart.00477.2022 · ExternalCitation · doi-reference
Resting heart rate and risk of cancer mortality
10.1158/1055-9965.epi-20-1731 · ExternalCitation · doi-reference
Elevated resting heart rate is an independent risk factor for mortality in patients with colorectal cancer: a retrospective cohort study
10.1158/1055-9965.epi-25-0704 · ExternalCitation · doi-reference
Molecular pathways: beta-adrenergic signaling in cancer
10.1158/1078-0432.ccr-11-0641 · ExternalCitation · doi-reference
Blood pressure responses during exercise: physiological correlates and clinical implications
10.1161/atvbaha.122.318512 · ExternalCitation · doi-reference
Relations of exercise blood pressure response to cardiovascular risk factors and vascular function in the Framingham heart study
10.1161/circulationaha.111.063933 · ExternalCitation · doi-reference
Systolic blood pressure response during exercise stress testing: the henry Ford ExercIse Testing (FIT) project
10.1161/jaha.115.002050 · ExternalCitation · doi-reference
Heart rate recovery and risk of cardiovascular events and all-cause mortality: a meta-analysis of prospective cohort studies
10.1161/jaha.117.005505 · ExternalCitation · doi-reference
Secular change in cardiorespiratory fitness of men: Cooper center longitudinal study
10.1249/mss.0b013e31821c00a7 · ExternalCitation · doi-reference
Heart rate and risk of cancer death in healthy men
10.1371/journal.pone.0021310 · ExternalCitation · doi-reference
Resting heart rate as a predictor of cancer mortality: a systematic review and meta-analysis
10.3390/jcm10071354 · ExternalCitation · doi-reference
Autonomic function and prognosis
10.3949/ccjm.76.s2.04 · ExternalCitation · doi-reference
The association between midlife cardiorespiratory fitness levels and later-life dementia: a cohort study
10.7326/0003-4819-158-3-201302050-00005 · ExternalCitation · doi-reference
