Research graph
References from The LEDA Score. Local targets link to admitted publications; unresolved targets remain external evidence.
A novel paradigm for heart failure with preserved ejection fraction
2013 · External reference
Diastolic and systolic heart failure are distinct phenotypes within the heart failure spectrum
10.1161/circulationaha.110.954388 · 2011 · External reference
Role of diastolic stress testing in the evaluation for heart failure with preserved ejection fraction: A simultaneous invasive-echocardiographic study
10.1161/circulationaha.116.024822 · 2017 · External reference
A simple diagnostic score for heart failure with preserved ejection fraction
10.1161/circulationaha.118.034646 · 2018 · External reference
How to diagnose heart failure with preserved ejection fraction: the HFA-PEFF diagnostic algorithm: a consensus recommendation from the Heart Failure Association (HFA) of the European Society of Cardiology (ESC)
10.1093/eurheartj/ehz641 · 2019 · External reference
Recommendations for the evaluation of left ventricular diastolic function by echocardiography and for heart failure with preserved ejection fraction diagnosis: an update from the American Society of Echocardiography
10.1016/j.echo.2025.03.011 · 2025 · External reference
Discordance between clinical assessment and invasive haemodynamics in heart failure
2019 · External reference
Echocardiographic diastolic function grading in HFpEF: testing the updated 2025 ASE criteria
10.1016/j.jacc.2025.11.024 · 2026 · External reference
Validation of the HFA-PEFF score for the diagnosis of heart failure with preserved ejection fraction
10.1002/ejhf.1614 · 2020 · External reference
The HFA-PEFF and H2FPEF scores largely disagree in classifying patients with suspected heart failure with preserved ejection fraction
10.1002/ejhf.2019 · 2021 · External reference
Utility and validity of the HFA-PEFF and H2FPEF scores in patients with symptomatic atrial fibrillation
10.1016/j.jchf.2024.01.015 · 2024 · External reference
Left atrial strain and haemodynamics in heart failure with preserved ejection fraction
10.1002/ejhf.1464 · 2019 · External reference
Left atrial expansion index for noninvasive estimation of pulmonary capillary wedge pressure: a cardiac catheterization validation study
10.1016/j.echo.2021.07.009 · 2021 · External reference
Left ventricular to left atrial volume ratio in the assessment of filling pressure in patients with dyspnoea and preserved ejection fraction
10.3389/fcvm.2024.1357006 · 2024 · External reference
Comparing pulmonary arterial wedge pressure and left ventricular end-diastolic pressure for assessment of left-sided filling pressures
10.1001/jamacardio.2018.0318 · 2018 · External reference
2021 ESC guidelines for the diagnosis and treatment of acute and chronic heart failure
10.1093/eurheartj/ehab368 · 2021 · External reference
2022 AHA/ACC/HFSA guideline for the management of heart failure: A report of the American College of Cardiology/American Heart Association Joint Committee on clinical practice guidelines
10.1016/j.jacc.2021.12.012 · 2022 · External reference
Practical guidance for hemodynamic assessment by right heart catheterization in managment of heart failure
10.1016/j.jchf.2024.03.020 · 2024 · External reference
Direct measurement of left atrial pressure during routine transradial catheterisation
10.14503/thij-15-5508 · 2016 · External reference
2023 ACC expert consensus decision pathway on management of heart failure with preserved ejection fraction: a report of the American College of Cardiology Solution Set Oversight Committee
10.1016/j.jacc.2023.03.393 · 2023 · External reference
Heart failure with preserved ejection fraction: JACC scientific statement
10.1016/j.jacc.2023.01.049 · 2023 · External reference
Natriuretic peptide response and outcomes in chronic heart failure with preserved ejection fraction
2018 · External reference
Practical algorithms for early diagnosis of heart failure and heart stress using NT-proBNP: a clinical consensus statement from the Heart Failure Association of the ESC
10.1002/ejhf.3036 · 2023 · External reference
Invasive hemodynamic characterization of heart failure with preserved ejection fraction
10.1016/j.hfc.2014.03.001 · 2014 · External reference
Wedge pressure predicts outcome in heart failure with preserved ejection fraction
10.1016/j.jchf.2017.08.005 · 2017 · External reference
Recommendations for cardiac chamber quantification by echocardiography in adults: an update from the American Sociery of Echocardiography and the European Association of Cardiovascular Imaging
10.1016/j.echo.2014.10.003 · 2015 · External reference
Definitions for a common standard for 2-D speckle tracking echocardiography: consensus document of the EACVI/ASE/Industry Task Force to standardize deformation imaging
10.1093/ehjci/jeu184 · 2015 · External reference
Echocardiographic estimation of left ventricular filling pressure
10.1093/ehjci/jex067 · 2017 · External reference
Standardization of left atrial, right ventricular, and right atrial deformation imaging using two-dimensional speckle tracking echocardiography: a consensus document of the EACV/ASE/Industry Task Force to standardize deformation imaging
10.1093/ehjci/jey042 · 2018 · External reference
Left atrial function: physiology, assessment, and clinical implications
10.1093/ejechocard/jeq175 · 2011 · External reference
Left heart remodelling in hypertensive patients: a comprehensive echocardiography and computed tomography study
10.3389/fcvm.2023.1295537 · 2023 · External reference
Phenotype-specific treatment of heart failure with preserved ejection fraction: a multiorgan roadmap
10.1161/circulationaha.116.021884 · 2016 · External reference
Clinical diabetic cardiomyopathy: a two-faced disease with restrictive and dilated phenotypes
10.1093/eurheartj/ehv134 · 2015 · External reference
Temporal trends in the incidence of and mortality associated with heart failure with preserved and reduced ejection fraction
10.1016/j.jchf.2018.03.006 · 2018 · External reference
Nitrosative stress drives heart failure with preserved ejection fraction
10.1038/s41586-019-1100-z · 2019 · External reference
Heart failure in chronic kidney disease: conclusions from a Kidney Disease: improving Global Outcomes (KDIGO) controversies conference
10.1016/j.kint.2019.02.022 · 2019 · External reference
Heart failure with preserved ejection fraction with CKD: a narrative review of a multispeciality disorder
10.1016/j.xkme.2023.100705 · 2023 · External reference
Evidence supporting the existence of a distinct obese phenotype of heart failure with preserved ejection fraction
10.1161/circulationaha.116.026807 · 2017 · External reference
Phenomapping for novel classification of heart failure with preserved ejection fraction
10.1161/circulationaha.114.010637 · 2015 · External reference
Deep-learning models for the echocardiographic assessment of diastolic dysfunction and heart failure with preserved ejection fraction
10.1016/j.jcmg.2021.04.010 · 2021 · External reference
Automated echocardiographic detection of heart failure with preserved ejection fraction using artificial intelligence
10.1016/j.jacadv.2023.100452 · 2023 · External reference
Pulmonary hypertension in HFpEF and HFrEF: JACC review topic of the week
10.1016/j.jacc.2020.06.069 · 2020 · External reference
The adipokine hypothesis of heart failure with preserved ejection fraction: a novel framework to explain pathogenesis and guide treatment
10.1016/j.jacc.2025.06.055 · 2025 · External reference
Determinants of left atrial reservoir and pump strain and use of atrial strain for the evaluation of left ventricular filling pressure
10.1093/ehjci/jeab194 · 2021 · External reference
Comparing pulmonary arterial wedge pressure and left ventricular end-diastolic pressure for assessment of left-sided filling pressures
10.1001/jamacardio.2018.0318 · ExternalCitation · doi-reference
Left atrial strain and haemodynamics in heart failure with preserved ejection fraction
10.1002/ejhf.1464 · ExternalCitation · doi-reference
Validation of the HFA-PEFF score for the diagnosis of heart failure with preserved ejection fraction
10.1002/ejhf.1614 · ExternalCitation · doi-reference
The HFA-PEFF and H2FPEF scores largely disagree in classifying patients with suspected heart failure with preserved ejection fraction
10.1002/ejhf.2019 · ExternalCitation · doi-reference
Practical algorithms for early diagnosis of heart failure and heart stress using NT-proBNP: a clinical consensus statement from the Heart Failure Association of the ESC
10.1002/ejhf.3036 · ExternalCitation · doi-reference
Recommendations for cardiac chamber quantification by echocardiography in adults: an update from the American Sociery of Echocardiography and the European Association of Cardiovascular Imaging
10.1016/j.echo.2014.10.003 · ExternalCitation · doi-reference
Left atrial expansion index for noninvasive estimation of pulmonary capillary wedge pressure: a cardiac catheterization validation study
10.1016/j.echo.2021.07.009 · ExternalCitation · doi-reference
Recommendations for the evaluation of left ventricular diastolic function by echocardiography and for heart failure with preserved ejection fraction diagnosis: an update from the American Society of Echocardiography
10.1016/j.echo.2025.03.011 · ExternalCitation · doi-reference
Invasive hemodynamic characterization of heart failure with preserved ejection fraction
10.1016/j.hfc.2014.03.001 · ExternalCitation · doi-reference
Automated echocardiographic detection of heart failure with preserved ejection fraction using artificial intelligence
10.1016/j.jacadv.2023.100452 · ExternalCitation · doi-reference
Pulmonary hypertension in HFpEF and HFrEF: JACC review topic of the week
10.1016/j.jacc.2020.06.069 · ExternalCitation · doi-reference
2022 AHA/ACC/HFSA guideline for the management of heart failure: A report of the American College of Cardiology/American Heart Association Joint Committee on clinical practice guidelines
10.1016/j.jacc.2021.12.012 · ExternalCitation · doi-reference
Heart failure with preserved ejection fraction: JACC scientific statement
10.1016/j.jacc.2023.01.049 · ExternalCitation · doi-reference
2023 ACC expert consensus decision pathway on management of heart failure with preserved ejection fraction: a report of the American College of Cardiology Solution Set Oversight Committee
10.1016/j.jacc.2023.03.393 · ExternalCitation · doi-reference
The adipokine hypothesis of heart failure with preserved ejection fraction: a novel framework to explain pathogenesis and guide treatment
10.1016/j.jacc.2025.06.055 · ExternalCitation · doi-reference
Echocardiographic diastolic function grading in HFpEF: testing the updated 2025 ASE criteria
10.1016/j.jacc.2025.11.024 · ExternalCitation · doi-reference
Wedge pressure predicts outcome in heart failure with preserved ejection fraction
10.1016/j.jchf.2017.08.005 · ExternalCitation · doi-reference
Temporal trends in the incidence of and mortality associated with heart failure with preserved and reduced ejection fraction
10.1016/j.jchf.2018.03.006 · ExternalCitation · doi-reference
Utility and validity of the HFA-PEFF and H2FPEF scores in patients with symptomatic atrial fibrillation
10.1016/j.jchf.2024.01.015 · ExternalCitation · doi-reference
Practical guidance for hemodynamic assessment by right heart catheterization in managment of heart failure
10.1016/j.jchf.2024.03.020 · ExternalCitation · doi-reference
Deep-learning models for the echocardiographic assessment of diastolic dysfunction and heart failure with preserved ejection fraction
10.1016/j.jcmg.2021.04.010 · ExternalCitation · doi-reference
Heart failure in chronic kidney disease: conclusions from a Kidney Disease: improving Global Outcomes (KDIGO) controversies conference
10.1016/j.kint.2019.02.022 · ExternalCitation · doi-reference
Heart failure with preserved ejection fraction with CKD: a narrative review of a multispeciality disorder
10.1016/j.xkme.2023.100705 · ExternalCitation · doi-reference
Nitrosative stress drives heart failure with preserved ejection fraction
10.1038/s41586-019-1100-z · ExternalCitation · doi-reference
Determinants of left atrial reservoir and pump strain and use of atrial strain for the evaluation of left ventricular filling pressure
10.1093/ehjci/jeab194 · ExternalCitation · doi-reference
Definitions for a common standard for 2-D speckle tracking echocardiography: consensus document of the EACVI/ASE/Industry Task Force to standardize deformation imaging
10.1093/ehjci/jeu184 · ExternalCitation · doi-reference
Echocardiographic estimation of left ventricular filling pressure
10.1093/ehjci/jex067 · ExternalCitation · doi-reference
Standardization of left atrial, right ventricular, and right atrial deformation imaging using two-dimensional speckle tracking echocardiography: a consensus document of the EACV/ASE/Industry Task Force to standardize deformation imaging
10.1093/ehjci/jey042 · ExternalCitation · doi-reference
Left atrial function: physiology, assessment, and clinical implications
10.1093/ejechocard/jeq175 · ExternalCitation · doi-reference
2021 ESC guidelines for the diagnosis and treatment of acute and chronic heart failure
10.1093/eurheartj/ehab368 · ExternalCitation · doi-reference
Clinical diabetic cardiomyopathy: a two-faced disease with restrictive and dilated phenotypes
10.1093/eurheartj/ehv134 · ExternalCitation · doi-reference
How to diagnose heart failure with preserved ejection fraction: the HFA-PEFF diagnostic algorithm: a consensus recommendation from the Heart Failure Association (HFA) of the European Society of Cardiology (ESC)
10.1093/eurheartj/ehz641 · ExternalCitation · doi-reference
Diastolic and systolic heart failure are distinct phenotypes within the heart failure spectrum
10.1161/circulationaha.110.954388 · ExternalCitation · doi-reference
Phenomapping for novel classification of heart failure with preserved ejection fraction
10.1161/circulationaha.114.010637 · ExternalCitation · doi-reference
Phenotype-specific treatment of heart failure with preserved ejection fraction: a multiorgan roadmap
10.1161/circulationaha.116.021884 · ExternalCitation · doi-reference
Role of diastolic stress testing in the evaluation for heart failure with preserved ejection fraction: A simultaneous invasive-echocardiographic study
10.1161/circulationaha.116.024822 · ExternalCitation · doi-reference
Evidence supporting the existence of a distinct obese phenotype of heart failure with preserved ejection fraction
10.1161/circulationaha.116.026807 · ExternalCitation · doi-reference
A simple diagnostic score for heart failure with preserved ejection fraction
10.1161/circulationaha.118.034646 · ExternalCitation · doi-reference
Direct measurement of left atrial pressure during routine transradial catheterisation
10.14503/thij-15-5508 · ExternalCitation · doi-reference
Left heart remodelling in hypertensive patients: a comprehensive echocardiography and computed tomography study
10.3389/fcvm.2023.1295537 · ExternalCitation · doi-reference
Left ventricular to left atrial volume ratio in the assessment of filling pressure in patients with dyspnoea and preserved ejection fraction
10.3389/fcvm.2024.1357006 · ExternalCitation · doi-reference
