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References from Cardiomyocyte Lineage Specification in Adult Human Cardiac Precursor Cells Via Modulation of Enhancer-Associated Long Noncoding RNA Expression. Local targets link to admitted publications; unresolved targets remain external evidence.
The failing heart
10.1038/415227a · 2002 · External reference
Cardiac stem cell therapy and the promise of heart regeneration
10.1016/j.stem.2013.05.008 · 2013 · External reference
An emerging consensus on cardiac regeneration
10.1038/nm.3764 · 2014 · External reference
Programming and reprogramming a human heart cell
10.15252/embj.201490563 · 2015 · External reference
Functional role of Notch signaling in the developing and postnatal heart
10.1016/j.yjmcc.2008.02.273 · 2008 · External reference
Coordinating tissue interactions: Notch signaling in cardiac development and disease
10.1016/j.devcel.2012.01.014 · 2012 · External reference
Notch signaling
10.1101/cshperspect.a011213 · 2012 · External reference
HES and HERP families: multiple effectors of the Notch signaling pathway
10.1002/jcp.10208 · 2003 · External reference
Inhibition of notch1-dependent cardiomyogenesis leads to a dilated myopathy in the neonatal heart
10.1161/circresaha.110.218487 · 2010 · External reference
Control of the adaptive response of the heart to stress via the Notch1 receptor pathway
10.1084/jem.20081427 · 2008 · External reference
Activation of Notch-mediated protective signaling in the myocardium
10.1161/circresaha.107.164749 · 2008 · External reference
Distinct roles for cell-autonomous Notch signaling in cardiomyocytes of the embryonic and adult heart
10.1161/circresaha.109.203034 · 2010 · External reference
A dynamic notch injury response activates epicardium and contributes to fibrosis repair
10.1161/circresaha.110.233262 · 2011 · External reference
The Notch pathway controls fibrotic and regenerative repair in the adult heart
10.1093/eurheartj/ehs269 · 2014 · External reference
Induction of cardiogenesis in embryonic stem cells via downregulation of Notch1 signaling
10.1161/01.res.0000226497.52052.2a · 2006 · External reference
Timely inhibition of Notch signaling by DAPT promotes cardiac differentiation of murine pluripotent stem cells
10.1371/journal.pone.0109588 · 2014 · External reference
Notch1 regulates the fate of cardiac progenitor cells
10.1073/pnas.0808357105 · 2008 · External reference
Notch activation enhances lineage commitment and protective signaling in cardiac progenitor cells
10.1007/s00395-015-0488-3 · 2015 · External reference
The role of notch 1 activation in cardiosphere derived cell differentiation
10.1089/scd.2011.0463 · 2012 · External reference
The miR-143/145 cluster is a novel transcriptional target of Jagged-1/Notch signaling in vascular smooth muscle cells
10.1074/jbc.m111.221945 · 2011 · External reference
miR-145 and miR-143 regulate smooth muscle cell fate and plasticity
10.1038/nature08195 · 2009 · External reference
lincRNAs act in the circuitry controlling pluripotency and differentiation
10.1038/nature10398 · 2011 · External reference
Long noncoding RNAs in cell-fate programming and reprogramming
10.1016/j.stem.2014.05.014 · 2014 · External reference
Functional importance of cardiac enhancer-associated noncoding RNAs in heart development and disease
10.1016/j.yjmcc.2014.08.009 · 2014 · External reference
Braveheart, a long noncoding RNA required for cardiovascular lineage commitment
10.1016/j.cell.2013.01.003 · 2013 · External reference
The tissue-specific lncRNA Fendrr is an essential regulator of heart and body wall development in the mouse
10.1016/j.devcel.2012.12.012 · 2013 · External reference
Genome-wide profiling of the cardiac transcriptome after myocardial infarction identifies novel heart-specific long non-coding RNAs
10.1093/eurheartj/ehu180 · 2015 · External reference
Long noncoding RNAs: from clinical genetics to therapeutic targets?
10.1016/j.jacc.2015.12.051 · 2016 · External reference
Long noncoding RNAs usher in a new era in the biology of enhancers
10.1016/j.cell.2013.08.028 · 2013 · External reference
The promise of enhancer-associated long noncoding RNAs in cardiac regeneration
10.1016/j.tcm.2015.01.014 · 2015 · External reference
Isolation of cardiovascular precursor cells from the human fetal heart
10.1089/ten.tea.2011.0022 · 2012 · External reference
CARMEN, a human super enhancer-associated long noncoding RNA controlling cardiac specification, differentiation and homeostasis
10.1016/j.yjmcc.2015.09.016 · 2015 · External reference
FGF-2 controls the differentiation of resident cardiac precursors into functional cardiomyocytes
10.1172/jci23418 · 2005 · External reference
edgeR: a Bioconductor package for differential expression analysis of digital gene expression data
10.1093/bioinformatics/btp616 · 2010 · External reference
voom: precision weights unlock linear model analysis tools for RNA-seq read counts
10.1186/gb-2014-15-2-r29 · 2014 · External reference
limma powers differential expression analyses for RNA-sequencing and microarray studies
10.1093/nar/gkv007 · 2015 · External reference
In search of the in vivo identity of mesenchymal stem cells
10.1634/stemcells.2007-1122 · 2008 · External reference
Cis-interactions between Notch and Delta generate mutually exclusive signalling states
10.1038/nature08959 · 2010 · External reference
Notch activates cell cycle reentry and progression in quiescent cardiomyocytes
10.1083/jcb.200806104 · 2008 · External reference
Notch1 signaling stimulates proliferation of immature cardiomyocytes
10.1083/jcb.200806091 · 2008 · External reference
Therapeutic antibody targeting of individual Notch receptors
10.1038/nature08878 · 2010 · External reference
Abnormal calcium handling properties underlie familial hypertrophic cardiomyopathy pathology in patient-specific induced pluripotent stem cells
10.1016/j.stem.2012.10.010 · 2013 · External reference
Enhancers as non-coding RNA transcription units: recent insights and future perspectives
10.1038/nrg.2016.4 · 2016 · External reference
Hopping to the beat. Hop regulation of cardiac gene expression
10.1016/s1050-1738(03)00107-5 · 2003 · External reference
Integration of Bmp and Wnt signaling by Hopx specifies commitment of cardiomyoblasts
10.1126/science.aaa6071 · 2015 · External reference
The multiple phases and faces of wnt signaling during cardiac differentiation and development
10.1161/circresaha.110.221531 · 2010 · External reference
Iroquois homeodomain transcription factors in heart development and function
10.1161/circresaha.112.265041 · 2012 · External reference
Functional cardiomyocytes derived from Isl1 cardiac progenitors via Bmp4 stimulation
10.1371/journal.pone.0110752 · 2014 · External reference
Stimulation of endogenous cardioblasts by exogenous cell therapy after myocardial infarction
10.1002/emmm.201303626 · 2014 · External reference
Neuregulin1/ErbB4 signaling induces cardiomyocyte proliferation and repair of heart injury
10.1016/j.cell.2009.04.060 · 2009 · External reference
Transcriptional reversion of cardiac myocyte fate during Mammalian cardiac regeneration
10.1161/circresaha.116.304269 · 2015 · External reference
Adult cardiac-resident MSC-like stem cells with a proepicardial origin
10.1016/j.stem.2011.10.002 · 2011 · External reference
Human myocardial pericytes: multipotent mesodermal precursors exhibiting cardiac specificity
10.1002/stem.1868 · 2015 · External reference
Cardiogenic genes expressed in cardiac fibroblasts contribute to heart development and repair
10.1161/circresaha.114.302530 · 2014 · External reference
Reprogramming of mouse fibroblasts into cardiomyocyte-like cells in vitro
10.1038/nprot.2013.067 · 2013 · External reference
Heart repair by reprogramming non-myocytes with cardiac transcription factors
10.1038/nature11139 · 2012 · External reference
Lineage reprogramming of fibroblasts into proliferative induced cardiac progenitor cells by defined factors
10.1016/j.stem.2015.12.001 · 2016 · External reference
Emerging concepts in paracrine mechanisms in regenerative cardiovascular medicine and biology
10.1161/circresaha.115.305373 · 2016 · External reference
MicroRNA miR145 regulates TGFBR2 expression and matrix synthesis in vascular smooth muscle cells
10.1161/circresaha.115.303970 · 2015 · External reference
Molecular regulation of vascular smooth muscle cell differentiation in development and disease
10.1152/physrev.00041.2003 · 2004 · External reference
The GENCODE v7 catalog of human long noncoding RNAs: analysis of their gene structure, evolution, and expression
10.1101/gr.132159.111 · 2012 · External reference
PolyA_DB: a database for mammalian mRNA polyadenylation
10.1093/nar/gki055 · 2005 · External reference
Long noncoding RNAs: cellular address codes in development and disease
10.1016/j.cell.2013.02.012 · 2013 · External reference