Research graph
References from Resourcing Drug Development Commensurate With its Public Health Importance. Local targets link to admitted publications; unresolved targets remain external evidence.
Heart disease and stroke statistics–2014 update: a report from the American Heart Association
2014 · External reference
Cardiovascular drug development: is it dead or just hibernating?
10.1016/j.jacc.2015.03.016 · 2015 · External reference
Temporal trends and factors associated with cardiovascular drug development, 1990 to 2012
2016 · External reference
Unresolved reference
External reference
Effects of different regimens to lower blood pressure on major cardiovascular events in older and younger adults: meta-analysis of randomised trials
10.1136/bmj.39548.738368.be · 2008 · External reference
Safety profile of extended-release niacin in the AIM-HIGH trial
10.1056/nejmc1311039 · 2014 · External reference
The effects of lowering LDL cholesterol with statin therapy in people at low risk of vascular disease: meta-analysis of individual data from 27 randomised trials
10.1016/s0140-6736(12)60367-5 · 2012 · External reference
The FDA and the future of cardiovascular medicine
10.1001/jamacardio.2016.2580 · 2016 · External reference
Effects of oral tolvaptan in patients hospitalized for worsening heart failure: the EVEREST Outcome trial
10.1001/jama.297.12.1319 · 2007 · External reference
Effect of phosphodiesterase-5 inhibition on exercise capacity and clinical status in heart failure with preserved ejection fraction: a randomized clinical trial
10.1001/jama.2013.2024 · 2013 · External reference
Unresolved reference
2016 · External reference
Effect of enalapril on survival in patients with reduced left ventricular ejection fractions and congestive heart failure
10.1056/nejm199108013250501 · 1991 · External reference
The effect of spironolactone on morbidity and mortality in patients with severe heart failure
10.1056/nejm199909023411001 · 1999 · External reference
Effect of carvedilol on the morbidity of patients with severe chronic heart failure: results of the Carvedilol Prospective Randomized Cumulative Survival (COPERNICUS) study
10.1161/01.cir.0000035653.72855.bf · 2002 · External reference
Effects of controlled-release metoprolol on total mortality, hospitalizations, and well-being in patients with heart failure: the Metoprolol CR/XL Randomized Intervention Trial in congestive heart failure (MERIT-HF)
10.1001/jama.283.10.1295 · 2000 · External reference
Effect of captopril on mortality and morbidity in patients with left ventricular dysfunction after myocardial infarction. Results of the Survival and Ventricular Enlargement trial
10.1056/nejm199209033271001 · 1992 · External reference
Unresolved reference
External reference