Research graph
References from Fine Tuning Adenylyl Cyclase as a (Gene) Therapy for Heart Failure. Local targets link to admitted publications; unresolved targets remain external evidence.
2013 ACCF/AHA guideline for the management of heart failure: a report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines
10.1016/j.jacc.2013.05.019 · 2013 · External reference
Angiotensin–neprilysin inhibition versus enalapril in heart failure
10.1056/nejmoa1409077 · 2014 · External reference
Ivabradine and outcomes in chronic heart failure (SHIFT): a randomised placebo-controlled study
10.1016/s0140-6736(10)61198-1 · 2010 · External reference
Cardiac-directed expression of adenylyl cyclase catalytic domain reverses cardiac dysfunction caused by sustained beta-adrenergic receptor stimulation
2016 · External reference
Adenylyl cyclase increases survival in cardiomyopathy
10.1161/01.cir.0000014968.54967.d3 · 2002 · External reference
Intracoronary gene transfer of adenylyl cyclase 6 in patients with heart failure: a randomized clinical trial
10.1001/jamacardio.2016.0008 · 2016 · External reference
The b-adrenergic pathway mediates norepinephrine-stimulated apoptosis in vitro in adult rat cardiac myocytes
1997 · External reference
Treatment of chronic heart failure with beta-adrenergic receptor antagonists: a convergence of receptor pharmacology and clinical cardiology
10.1161/circresaha.111.245092 · 2011 · External reference
Temporal analysis of mRNA and miRNA expression in transgenic mice overexpressing Arg- and Gly389 polymorphic variants of the beta1-adrenergic receptor
10.1152/physiolgenomics.00067.2011 · 2011 · External reference
Overexpression of Gs alpha protein in the hearts of transgenic mice
10.1172/jci117843 · 1995 · External reference
Dilated cardiomyopathy and sudden death resulting from constitutive activation of protein kinase A
10.1161/hh2301.100003 · 2001 · External reference
CaMKII inhibition in heart failure, beneficial, harmful, or both
10.1152/ajpheart.00812.2011 · 2012 · External reference
Beneficial effects of adenylyl cyclase type 6 (AC6) expression persist using a catalytically inactive AC6 mutant
10.1124/mol.110.067298 · 2011 · External reference
Adenylyl cyclase 6 improves calcium uptake and left ventricular function in aged hearts
10.1016/j.jacc.2010.11.052 · 2011 · External reference
Adenylyl cyclase 6 deletion increases mortality during sustained beta-adrenergic receptor stimulation
10.1016/j.yjmcc.2013.04.005 · 2013 · External reference
Preserved cardiac function despite marked impairment of cAMP generation
10.1371/journal.pone.0072151 · 2013 · External reference
Adenylyl cyclase type VI increases Akt activity and phospholamban phosphorylation in cardiac myocytes
10.1074/jbc.m805825200 · 2008 · External reference
Effect of metoprolol on myocardial function and energetics in patients with nonischemic dilated cardiomyopathy: a randomized, double-blind, placebo-controlled study
10.1016/0735-1097(94)90114-7 · 1994 · External reference
Therapeutic molecular phenotype of beta-blocker-associated reverse-remodeling in nonischemic dilated cardiomyopathy
10.1161/circgenetics.114.000767 · 2015 · External reference
Calcium Upregulation by Percutaneous Administration of Gene Therapy in Cardiac Disease (CUPID): a phase 2 trial of intracoronary gene therapy of sarcoplasmic reticulum Ca2+-ATPase in patients with advanced heart failure
10.1161/circulationaha.111.022889 · 2011 · External reference
