Research graph
References from A Growth Tonic for Heart Failure?. Local targets link to admitted publications; unresolved targets remain external evidence.
Purification and partial characterization of a cholinergic neuronal differentiation factor
10.1073/pnas.82.24.8795 · 1985 · External reference
Neuregulins and their receptors: a versatile signaling module in organogenesis and oncogenesis
10.1016/s0896-6273(00)80324-4 · 1997 · External reference
Role of neuregulin-1/ErbB2 signaling in endothelium-cardiomyocyte cross-talk
10.1074/jbc.m600399200 · 2006 · External reference
Exercise training activates neuregulin 1/ErbB signaling and promotes cardiac repair in a rat myocardial infarction model
10.1016/j.lfs.2016.02.055 · 2016 · External reference
Neuregulin stimulation of cardiomyocyte regeneration in mice and human myocardium reveals a therapeutic window
10.1126/scitranslmed.aaa5171 · 2015 · External reference
ERBB2 triggers mammalian heart regeneration by promoting cardiomyocyte dedifferentiation and proliferation
10.1038/ncb3149 · 2015 · External reference
Neuregulin1/ErbB4 signaling induces cardiomyocyte proliferation and repair of heart injury
10.1016/j.cell.2009.04.060 · 2009 · External reference
Recombinant neuregulin 1 does not activate cardiomyocyte DNA synthesis in normal or infarcted adult mice
10.1371/journal.pone.0115871 · 2014 · External reference
Neuregulin-1beta induces mature ventricular cardiac differentiation from induced pluripotent stem cells contributing to cardiac tissue repair
10.1089/scd.2014.0211 · 2015 · External reference
Neuregulin/ErbB signaling regulates cardiac subtype specification in differentiating human embryonic stem cells
10.1161/circresaha.110.223917 · 2010 · External reference
Neuregulin-1 promotes cardiomyocyte differentiation of genetically engineered embryonic stem cell clones
10.5483/bmbrep.2008.41.10.699 · 2008 · External reference
Neuregulin-1beta promotes glucose uptake via PI3K/Akt in neonatal rat cardiomyocytes
10.1152/ajpendo.00259.2015 · 2016 · External reference
Anti-remodeling and anti-fibrotic effects of the neuregulin-1beta glial growth factor 2 in a large animal model of heart failure
10.1161/jaha.113.000773 · 2014 · External reference
Neuregulins promote survival and growth of cardiac myocytes. Persistence of ErbB2 and ErbB4 expression in neonatal and adult ventricular myocytes
10.1074/jbc.273.17.10261 · 1998 · External reference
An engineered bivalent neuregulin protects against doxorubicin-induced cardiotoxicity with reduced proneoplastic potential
10.1161/circulationaha.113.002203 · 2013 · External reference
Anti-erbB2 treatment induces cardiotoxicity by interfering with cell survival pathways
10.1186/bcr1523 · 2006 · External reference
An optimized dosing regimen of cimaglermin (neuregulin 1beta3, glial growth factor 2) enhances molecular markers of neuroplasticity and functional recovery after permanent ischemic stroke in rats
10.1002/jnr.23699 · 2016 · External reference
A phase I, single ascending dose study of cimaglermin alfa (neuregulin 1β3) in patients with systolic dysfunction and heart failure
2016 · External reference
A phase II, randomized, double-blind, multicenter, based on standard therapy, placebo-controlled study of the efficacy and safety of recombinant human neuregulin-1 in patients with chronic heart failure
10.1016/j.jacc.2009.12.044 · 2010 · External reference
ErbB2 signaling at the crossing between heart failure and cancer
10.1007/s00395-016-0576-z · 2016 · External reference
