Research graph
References from Human Second Window Pre-Conditioning and Post-Conditioning by Nitrite Is Influenced by a Common Polymorphism in Mitochondrial Aldehyde Dehydrogenase. Local targets link to admitted publications; unresolved targets remain external evidence.
The emerging biology of the nitrite anion
10.1038/nchembio1105-308 · 2005 · External reference
The nitrate-nitrite-nitric oxide pathway in physiology and therapeutics
10.1038/nrd2466 · 2008 · External reference
Therapeutic effects of inorganic nitrate and nitrite in cardiovascular and metabolic diseases
10.1111/joim.12441 · 2016 · External reference
Hypoxic modulation of exogenous nitrite-induced vasodilation in humans
10.1161/circulationaha.107.719591 · 2008 · External reference
Role for endothelial nitric oxide synthase in nitrite-induced protection against renal ischemia-reperfusion injury in mice
10.1016/j.niox.2009.10.010 · 2010 · External reference
Role of the anion nitrite in ischemia-reperfusion cytoprotection and therapeutics
10.1016/j.cardiores.2007.05.001 · 2007 · External reference
Cytoprotective effects of nitrite during in vivo ischemia-reperfusion of the heart and liver
10.1172/jci22493 · 2005 · External reference
Nitrite anion provides potent cytoprotective and antiapoptotic effects as adjunctive therapy to reperfusion for acute myocardial infarction
10.1161/circulationaha.107.748814 · 2008 · External reference
Acute blood pressure lowering, vasoprotective, and antiplatelet properties of dietary nitrate via bioconversion to nitrite
10.1161/hypertensionaha.107.103523 · 2008 · External reference
Low-dose sodium nitrite attenuates myocardial ischemia and vascular ischemia-reperfusion injury in human models
10.1016/j.jacc.2013.03.050 · 2013 · External reference
Intravenous sodium nitrite in acute ST-elevation myocardial infarction: a randomized controlled trial (NIAMI)
10.1093/eurheartj/ehu096 · 2014 · External reference
Analysis and update of the human aldehyde dehydrogenase (ALDH) gene family
10.1186/1479-7364-2-2-138 · 2005 · External reference
Population genetic studies on aldehyde dehydrogenase isozyme deficiency and alcohol sensitivity
1983 · External reference
Disruption of the coenzyme binding site and dimer interface revealed in the crystal structure of mitochondrial aldehyde dehydrogenase “Asian” variant
10.1074/jbc.m502345200 · 2005 · External reference
The ALDH2 Glu504Lys polymorphism is associated with coronary artery disease in Han Chinese: relation with endothelial ADMA levels
10.1016/j.atherosclerosis.2010.03.030 · 2010 · External reference
Aldehyde dehydrogenase 2 gene is a risk factor for myocardial infarction in Japanese men
10.1291/hypres.25.677 · 2002 · External reference
Activation of aldehyde dehydrogenase-2 reduces ischemic damage to the heart
10.1126/science.1158554 · 2008 · External reference
Isoflurane preconditioning confers cardioprotection by activation of ALDH2
10.1371/journal.pone.0052469 · 2013 · External reference
Bioactivation of nitroglycerin by purified mitochondrial and cytosolic aldehyde dehydrogenases
10.1074/jbc.m801182200 · 2008 · External reference
Ischemic preconditioning prevents endothelial injury and systemic neutrophil activation during ischemia-reperfusion in humans in vivo
10.1161/01.cir.103.12.1624 · 2001 · External reference
Cellular targets and mechanisms of nitros(yl)ation: an insight into their nature and kinetics in vivo
10.1073/pnas.0306706101 · 2004 · External reference
Characterization of the East Asian variant of aldehyde dehydrogenase-2: bioactivation of nitroglycerin and effects of Alda-1
10.1074/jbc.m109.014548 · 2010 · External reference
Aldehyde dehydrogenase-2 inhibition blocks remote preconditioning in experimental and human models
10.1007/s00395-013-0343-3 · 2013 · External reference
Cardioprotective function of inducible nitric oxide synthase and role of nitric oxide in myocardial ischemia and preconditioning: an overview of a decade of research
10.1006/jmcc.2001.1462 · 2001 · External reference
Nitrite augments tolerance to ischemia/reperfusion injury via the modulation of mitochondrial electron transfer
10.1084/jem.20070198 · 2007 · External reference
Ischaemia-reperfusion injury impairs tissue plasminogen activator release in man
10.1093/eurheartj/ehr380 · 2012 · External reference
In vivo post-cardiac arrest myocardial dysfunction is supported by Ca2+/calmodulin-dependent protein kinase II-mediated calcium long-term potentiation and mitigated by Alda-1, an agonist of aldehyde dehydrogenase type 2
10.1161/circulationaha.116.021618 · 2016 · External reference
Circulating nitrite contributes to cardioprotection by remote ischemic preconditioning
10.1161/circresaha.114.303822 · 2014 · External reference
Is nitrite the circulating endocrine effector of remote ischemic preconditioning?
10.1161/circresaha.114.303960 · 2014 · External reference
Ischaemic conditioning and targeting reperfusion injury: a 30 year voyage of discovery
10.1007/s00395-016-0588-8 · 2016 · External reference