Research graph
References from Genetic variants associated with clinical characteristics and atopies in eosinophilic esophagitis. Local targets link to admitted publications; unresolved targets remain external evidence.
Prevalence of eosinophilic esophagitis doubles in less than a decade: a population-based study in 2 regions of Spain
10.18176/jiaci.1161 · 2026 · External reference
Eosinophilic esophagitis prevalence, incidence, and presenting features: a 22-year population-based observational study from southwest Sweden
10.1093/dote/doae025 · 2025 · External reference
Economic burden of eosinophilic esophagitis in the first year after diagnosis in Spain: a direct medical cost analysis
2025 · External reference
Prevalence and costs of eosinophilic esophagitis in the United States
10.1016/j.cgh.2024.09.031 · 2025 · External reference
ACG clinical guideline: diagnosis and management of eosinophilic esophagitis
10.14309/ajg.0000000000003194 · 2025 · External reference
Differences between childhood- and adulthood-onset eosinophilic esophagitis: an analysis from the EoE connect registry
10.1016/j.dld.2022.09.020 · 2023 · External reference
Sex-related differences in the presentation, management and response to treatment of eosinophilic esophagitis: cross sectional analysis of EoE CONNECT registry
10.1002/ueg2.12699 · 2024 · External reference
Guidelines on eosinophilic esophagitis: evidence-based statements and recommendations for diagnosis and management in children and adults
10.1177/2050640616689525 · 2017 · External reference
Fibrous remodeling in eosinophilic esophagitis: clinical facts and pathophysiological uncertainties
10.3390/ijms25020927 · 2024 · External reference
Determinant factors of quality of life in adult patients with eosinophilic esophagitis
10.1177/2050640617707095 · 2018 · External reference
Endoscopic assessment of the oesophageal features of eosinophilic oesophagitis: validation of a novel classification and grading system
10.1136/gutjnl-2011-301817 · 2013 · External reference
EoE CONNECT, the European Registry of Clinical, Environmental, and Genetic Determinants in Eosinophilic Esophagitis: rationale, design, and study protocol of a large-scale epidemiological study in Europe
10.1177/17562848221074204 · 2022 · External reference
Association between atopic manifestations and eosinophilic esophagitis: a systematic review and meta-analysis
10.1016/j.anai.2017.02.006 · 2017 · External reference
Eosinophilic esophagitis and allergic susceptibility: a systematic review and meta-analysis
10.1016/j.waojou.2025.101054 · 2025 · External reference
Risk and protective factors for childhood asthma: what is the evidence?
10.1016/j.jaip.2016.05.003 · 2016 · External reference
Prenatal, intrapartum, and neonatal factors increase the risk of eosinophilic esophagitis
10.14309/ajg.0000000000002303 · 2023 · External reference
The epithelial barrier theory and its associated diseases
10.1111/all.16318 · 2024 · External reference
Eosinophilic esophagitis: an allergy and immunology perspective on the updated guidelines
10.1016/j.jaci.2025.04.026 · 2025 · External reference
Twin and family studies reveal strong environmental and weaker genetic cues explaining heritability of eosinophilic esophagitis
10.1016/j.jaci.2014.07.021 · 2014 · External reference
Nature with nurture: the role of intrinsic genetic and extrinsic environmental factors on eosinophilic esophagitis
10.1007/s11882-022-01042-1 · 2022 · External reference
Role of genetics, environment, and their interactions in the pathogenesis of eosinophilic esophagitis
10.1016/j.coi.2019.04.004 · 2019 · External reference
Replication and meta-analyses nominate numerous eosinophilic esophagitis risk genes
10.1016/j.jaci.2020.10.018 · 2021 · External reference
Genetic and molecular contributors in eosinophilic esophagitis
10.1007/s11882-023-01075-0 · 2023 · External reference
Eosinophilic esophagitis endotype classification by molecular, clinical, and histopathological analyses: a cross sectional study by the Consortium of Eosinophilic Gastrointestinal Disease Researchers (CEGIR)
10.1016/s2468-1253(18)30096-7 · 2018 · External reference
Esophageal type 2 cytokine expression heterogeneity in eosinophilic esophagitis in a multisite cohort
10.1016/j.jaci.2020.01.051 · 2020 · External reference
Novel transcriptomic panel identifies histologically active eosinophilic oesophagitis
10.1136/gutjnl-2023-331743 · 2024 · External reference
Systematic identification of genotype-dependent enhancer variants in eosinophilic esophagitis
10.1016/j.ajhg.2023.12.008 · 2024 · External reference
STrengthening the REporting of Genetic Association Studies (STREGA)—an extension of the STROBE statement
10.1002/gepi.20410 · 2009 · External reference
GWAS identifies four novel eosinophilic esophagitis loci
10.1038/ncomms6593 · 2014 · External reference
The TGFβ1 promoter SNP C-509T and food sensitization promote esophageal remodeling in pediatric eosinophilic esophagitis
10.1371/journal.pone.0144651 · 2015 · External reference
Genetic variations in the TLR3 locus are associated with eosinophilic esophagitis
10.1177/2050640617732643 · 2018 · External reference
Common variants at 5q22 associate with pediatric eosinophilic esophagitis
10.1038/ng.547 · 2010 · External reference
Variants of thymic stromal lymphopoietin and its receptor associate with eosinophilic esophagitis
10.1016/j.jaci.2010.04.037 · 2010 · External reference
Genome-wide association analysis of eosinophilic esophagitis provides insight into the tissue specificity of this allergic disease
10.1038/ng.3033 · 2014 · External reference
Unresolved reference
External reference
A global reference for human genetic variation
10.1038/nature15393 · 2015 · External reference
Meta-analysis identifies seven susceptibility loci involved in the atopic march
10.1038/ncomms9804 · 2015 · External reference
Association study of childhood food allergy with genome-wide association studies-discovered loci of atopic dermatitis and eosinophilic esophagitis
10.1016/j.jaci.2017.05.034 · 2017 · External reference
Efficacy of proton pump inhibitor therapy for eosinophilic oesophagitis in 630 patients: results from the EoE connect registry
10.1111/apt.15957 · 2020 · External reference
Proton pump inhibitor therapy in eosinophilic esophagitis: predictors of nonresponse
10.1007/s10620-020-06633-4 · 2021 · External reference
Predictors of persistent symptoms in eosinophilic esophagitis after remission: fibrostenosis, eosinophilia, anxiety, and depression
10.1093/dote/doae110 · 2025 · External reference
The index of severity for eosinophilic esophagitis helps predict treatment response to dupilumab
2025 · External reference
Assessing the risk factors for refractory eosinophilic esophagitis in children and adults
10.1155/2019/1654543 · 2019 · External reference
Allergic phenotype identified on allergen testing is associated with proton pump inhibitor nonresponse in eosinophilic esophagitis
10.1111/jgh.16469 · 2024 · External reference
A systematic review of ABCB1 polymorphisms and antiseizure medication resistance: insights from effect size and study power analysis
10.3390/ijms26125548 · 2025 · External reference
The expression quantitative trait loci in immune pathways and their effect on cutaneous melanoma prognosis
10.1158/1078-0432.ccr-15-2066 · 2016 · External reference
Assessment of molecular subtypes in thyrotoxic periodic paralysis and Graves disease among Chinese Han Adults: a population-based genome-wide association study
10.1001/jamanetworkopen.2019.3348 · 2019 · External reference
A novel, noninvasive method to diagnose active eosinophilic esophagitis, combining clinical data and oral cavity RNA levels
10.1016/j.cgh.2023.07.023 · 2024 · External reference
Delay in diagnosis of eosinophilic esophagitis increases risk for stricture formation in a time-dependent manner
10.1053/j.gastro.2013.08.015 · 2013 · External reference
Impact of diagnostic delay and other risk factors on eosinophilic esophagitis phenotype and esophageal diameter
10.1097/mcg.0000000000000297 · 2016 · External reference
Eosinophilic esophagitis-linked calpain 14 is an IL-13-induced protease that mediates esophageal epithelial barrier impairment
10.1172/jci.insight.86355 · 2016 · External reference
Th2 cell-selective enhancement of human IL13 transcription by IL13-1112C>T, a polymorphism associated with allergic inflammation
10.4049/jimmunol.177.12.8633 · 2006 · External reference
Case-control study of IL13 polymorphisms, smoking, and rhinoconjunctivitis in Japanese women: the Kyushu Okinawa Maternal and Child Health Study
10.1186/1471-2350-12-143 · 2011 · External reference
Impact of STAT6 variants on the response to proton pump inhibitors and comorbidities in patients with eosinophilic esophagitis
10.3390/ijms25073685 · 2024 · External reference
Association of STAT6 variants with asthma risk: a systematic review and meta-analysis
10.1016/j.humimm.2014.06.007 · 2014 · External reference
Metabolome analysis reveals dermal histamine accumulation in murine dermatitis provoked by genetic deletion of P-glycoprotein and breast cancer resistance protein
10.1007/s11095-019-2695-3 · 2019 · External reference
ABCB1 in dermatology: roles in skin diseases and their treatment
10.1007/s00109-021-02105-y · 2021 · External reference
Polymorphisms in human MDR1 (P-glycoprotein): recent advances and clinical relevance
10.1016/j.clpt.2003.09.012 · 2004 · External reference
A genome-wide association meta-analysis identifies new eosinophilic esophagitis loci
10.1016/j.jaci.2021.08.018 · 2022 · External reference
Genome-wide admixture and association analysis identifies African ancestry-specific risk loci of eosinophilic esophagitis in African Americans
10.1016/j.jaci.2022.09.040 · 2023 · External reference
Multi-trait analysis of GWAS expands eosinophilic esophagitis genetic susceptibility and polygenic risk scores
2025 · External reference
