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References from Valorization of microwave-assisted optimized pomelo peel extract mitigates bisphenol A–induced oxidative stress and premature aging in Drosophila and disruption of myogenesis in C2C12 cells. Local targets link to admitted publications; unresolved targets remain external evidence.
Cellular and molecular mechanisms of muscle atrophy
10.1242/dmm.010389 · 2013 · External reference
Sarcopenia: definition, epidemiology, and pathophysiology
10.11005/jbm.2013.20.1.1 · 2013 · External reference
An overview of sarcopenia: facts and numbers on prevalence and clinical impact
10.1007/s13539-010-0014-2 · 2010 · External reference
Sarcopenia: current insights into molecular mechanisms, diagnostics, and emerging interventional approaches
10.3390/ijms26146740 · 2025 · External reference
Effects of endocrine disrupting chemicals (EDCs) on skeletal system development: a review
2023 · External reference
How body burden from exposure to endocrine disruptors effects accelerated aging?
10.35208/ert.1334434 · 2023 · External reference
Obesogens: how they are identified and molecular mechanisms underlying their action
10.3389/fendo.2021.780888 · 2021 · External reference
Nephrotoxicity of phthalates: a review based on epidemiological and toxicological evidence
10.3390/toxics13110947 · 2025 · External reference
Metabolic perturbations underlying the associations of endocrine-disrupting chemical mixtures with muscle mass and strength in adults: a repeated-measures study
10.1016/j.enceco.2025.08.019 · 2025 · External reference
The mixed effect of endocrine-disrupting chemicals on biological age acceleration: unveiling the mechanism and potential intervention target
10.1016/j.envint.2024.108447 · 2024 · External reference
Effects of bisphenol A on oxidative stress in the Rat brain
10.3390/antiox9030240 · 2020 · External reference
Bisphenol-A abrogates proliferation and differentiation of C2C12 mouse myoblasts via downregulation of Phospho-P65 NF-κB signaling pathway
2024 · External reference
Signaling pathways that control muscle mass
10.3390/ijms21134759 · 2020 · External reference
Optimization of phytochemical-rich citrus maxima Albedo extract using response surface methodology
10.3390/molecules28104121 · 2023 · External reference
Bioactive flavonoids metabolites in citrus species: their potential health benefits and medical potentials
2025 · External reference
Recovery, bioactivity, and utilization of bioactive phenolic compounds in citrus peel
10.1002/fsn3.4570 · 2024 · External reference
Antioxidant and anti-inflammatory activity through inhibition of NF-κB and sEH of some citrus peel and phytoconstituent characteristics
10.1016/j.jsps.2024.101959 · 2024 · External reference
Valorization of pomelo (Citrus grandis Osbeck) peel: a review of current utilization, phytochemistry, bioactivities, and mechanisms of action
10.1111/1541-4337.12561 · 2020 · External reference
Extracts of pomelo peels prevent high-fat diet-induced metabolic disorders in c57bl/6 mice through activating the PPARα and GLUT4 pathway
10.1371/journal.pone.0077915 · 2013 · External reference
Ficus lindsayana leaf extract protects C2C12 Mouse myoblasts against the suppressive effects of Bisphenol-A on Myogenic differentiation
10.3390/ijms26020476 · 2025 · External reference
Aging mechanisms-A perspective mostly from Drosophila
2020 · External reference
Mechanisms of skeletal muscle aging: insights from Drosophila and mammalian models
2013 · External reference
Impact of drying processes on phenolics and in vitro health-related activities of Indigenous plants in Thailand
2022 · External reference
Analysis of phytonutrients, anti-mutagenic and chemopreventive effects of tropical fruit extracts
10.3390/foods10112600 · 2021 · External reference
Microwave-assisted optimization extraction for green chili paste and investigation of its alpha-glucosidase inhibitory activity with molecular docking and molecular dynamics simulation for anti-diabetic potential
2025 · External reference
In vitro phytotherapeutic properties of aqueous extracted Adenia viridiflora craib. towards civilization diseases
10.3390/molecules26041082 · 2021 · External reference
Effects of curcuminoids identified in rhizomes of Curcuma longa on BACE-1 inhibitory and behavioral activity and lifespan of Alzheimer's disease Drosophila models
10.1186/1472-6882-14-88 · 2014 · External reference
Characterization of a Drosophila Alzheimer's disease model: pharmacological rescue of cognitive defects
10.1371/journal.pone.0020799 · 2011 · External reference
Diplazium esculentum (Retz.) Sw. reduces BACE-1 activities and amyloid peptides accumulation in Drosophila models of Alzheimer's disease
10.1038/s41598-021-03142-w · 2021 · External reference
In vitro effects of emerging bisphenols on myocyte differentiation and insulin responsiveness
10.1093/toxsci/kfaa130 · 2020 · External reference
Anoectochilus burmannicus extract rescues aging-related phenotypes in Drosophila susceptible to oxidative stress-induced senescence
10.3390/ijms26125694 · 2025 · External reference
The effect of resveratrol on lifespan depends on both gender and dietary nutrient composition in Drosophila melanogaster
10.1007/s11357-011-9332-3 · 2013 · External reference
The Him gene reveals a balance of inputs controlling muscle differentiation in Drosophila
10.1016/j.cub.2007.07.039 · 2007 · External reference
A review on insoluble-bound phenolics in plant-based food matrix and their contribution to human health with future perspectives
10.1016/j.tifs.2020.09.029 · 2020 · External reference
Response surface methodology-optimized extraction of flavonoids from pomelo peels and isolation of naringin with antioxidant activities by Sephadex LH20 gel chromatography
10.1016/j.crfs.2023.100610 · 2023 · External reference
Optimized conditions for flavonoid extraction from Pomelo Peel byproducts under Enzyme- and ultrasound-assisted extraction using response surface methodology
2021 · External reference
Guidelines for the extraction of plant polyphenols using microwave-assisted techniques
10.1002/fci2.70022 · 2025 · External reference
Mitohormesis: promoting health and lifespan by increased levels of Reactive Oxygen Species (ROS)
10.2203/dose-response.13-035.ristow · 2014 · External reference
Sexual dimorphism in the nutritional requirement for adult lifespan in Drosophila melanogaster
10.1111/acel.13120 · 2020 · External reference
Comparisons of lifespan and stress resistance between sexes in Drosophila melanogaster
10.1016/j.heliyon.2023.e18178 · 2023 · External reference
Naringenin modulates skeletal muscle differentiation via estrogen receptor α and β signal pathway regulation
10.1007/s12263-014-0425-3 · 2014 · External reference
Nuclear receptors--a perspective from Drosophila
10.1038/nrg1581 · 2005 · External reference
Drosophila estrogen-related receptor directs a transcriptional switch that supports adult glycolysis and lipogenesis
10.1101/gad.335281.119 · 2020 · External reference
Mechanisms and functions of Nrf2 signaling in Drosophila
10.1016/j.freeradbiomed.2015.06.020 · 2015 · External reference
Supplementation of Citrus maxima peel powder prevented oxidative stress, fibrosis, and hepatic damage in carbon tetrachloride (CCl4) treated rats
10.1155/2015/598179 · 2015 · External reference
Naringin mitigates LPS-induced intestinal barrier injury in mice
10.1039/d2fo03586c · 2023 · External reference
Cellular and molecular mechanisms of sarcopenia: the S100B perspective
10.1002/jcsm.12363 · 2018 · External reference
Natural flavonoid luteolin promotes the differentiation of porcine myoblasts through activation of PI3K/Akt/mTOR signaling
10.1016/j.fbio.2022.101766 · 2022 · External reference
Castor oil plant (Ricinus communis L.) leaves improve dexamethasone-induced muscle atrophy via Nrf2 activation
10.3389/fphar.2022.891762 · 2022 · External reference
Hexavalent chromium inhibits myogenic differentiation and induces myotube atrophy
10.1016/j.taap.2023.116693 · 2023 · External reference
Propylparaben impairs muscle development in zebrafish via the PI3K-mTOR pathway
10.1016/j.ecoenv.2025.118985 · 2025 · External reference
Monotropein improves dexamethasone-induced muscle atrophy via the AKT/mTOR/FOXO3a signaling pathways
10.3390/nu14091859 · 2022 · External reference
20(S)-ginsenoside Rg3 promotes myoblast differentiation and protects against myotube atrophy via regulation of the Akt/mTOR/FoxO3 pathway
10.1016/j.bcp.2020.114145 · 2020 · External reference
Ginsenoside Rb1 and Rb2 upregulate Akt/mTOR signaling–mediated muscular hypertrophy and myoblast differentiation
10.1016/j.jgr.2019.01.007 · 2020 · External reference
Myogenic differentiation is dependent on both the kinase function and the N-terminal sequence of Mammalian target of rapamycin
10.1074/jbc.m112285200 · 2002 · External reference
Activation of eIF4E-binding-protein-1 rescues mTORC1-induced sarcopenia by expanding lysosomal degradation capacity
10.1002/jcsm.13121 · 2023 · External reference
The oxidation of 2',7'-dichlorofluorescin to reactive oxygen species: a self-fulfilling prophesy?
10.1016/j.freeradbiomed.2005.10.042 · 2006 · External reference
Skeletal muscle wasting with disuse atrophy is multi-dimensional: the response and interaction of myonuclei, satellite cells and signaling pathways
10.3389/fphys.2014.00099 · 2014 · External reference
Prevalence and mechanisms of skeletal muscle atrophy in metabolic conditions
10.3390/ijms24032973 · 2023 · External reference
Sarcopenic obesity: involvement of oxidative stress and beneficial role of antioxidant flavonoids
10.3390/antiox12051063 · 2023 · External reference
Plasma kinetics and urinary excretion of the flavanones naringenin and hesperetin in humans after ingestion of orange juice and grapefruit juice
10.1093/jn/131.2.235 · 2001 · External reference
Pharmacokinetics of the citrus flavanone aglycones hesperetin and naringenin after single oral administration in human subjects
10.1038/sj.ejcn.1602543 · 2007 · External reference
Arsenic induces apoptosis in myoblasts through a reactive oxygen species-induced endoplasmic reticulum stress and mitochondrial dysfunction pathway
10.1007/s00204-012-0864-9 · 2012 · External reference
Endocrine-disrupting chemicals and their adverse effects on the endoplasmic reticulum
10.3390/ijms23031581 · 2022 · External reference
Inflammatory cytokines inhibit myogenic differentiation through activation of nuclear factor-κΒ
10.1096/fj.00-0463 · 2001 · External reference
Procymidone induces muscle atrophy and impaired myocyte fusion via the TNF-α/NF-κB/ROS pathway in developing zebrafish embryos
10.1016/j.envpol.2026.127760 · 2026 · External reference
Guidelines for the extraction of plant polyphenols using microwave-assisted techniques
10.1002/fci2.70022 · ExternalCitation · doi-reference
Recovery, bioactivity, and utilization of bioactive phenolic compounds in citrus peel
10.1002/fsn3.4570 · ExternalCitation · doi-reference
Cellular and molecular mechanisms of sarcopenia: the S100B perspective
10.1002/jcsm.12363 · ExternalCitation · doi-reference
Activation of eIF4E-binding-protein-1 rescues mTORC1-induced sarcopenia by expanding lysosomal degradation capacity
10.1002/jcsm.13121 · ExternalCitation · doi-reference
Arsenic induces apoptosis in myoblasts through a reactive oxygen species-induced endoplasmic reticulum stress and mitochondrial dysfunction pathway
10.1007/s00204-012-0864-9 · ExternalCitation · doi-reference
The effect of resveratrol on lifespan depends on both gender and dietary nutrient composition in Drosophila melanogaster
10.1007/s11357-011-9332-3 · ExternalCitation · doi-reference
Naringenin modulates skeletal muscle differentiation via estrogen receptor α and β signal pathway regulation
10.1007/s12263-014-0425-3 · ExternalCitation · doi-reference
An overview of sarcopenia: facts and numbers on prevalence and clinical impact
10.1007/s13539-010-0014-2 · ExternalCitation · doi-reference
20(S)-ginsenoside Rg3 promotes myoblast differentiation and protects against myotube atrophy via regulation of the Akt/mTOR/FoxO3 pathway
10.1016/j.bcp.2020.114145 · ExternalCitation · doi-reference
Response surface methodology-optimized extraction of flavonoids from pomelo peels and isolation of naringin with antioxidant activities by Sephadex LH20 gel chromatography
10.1016/j.crfs.2023.100610 · ExternalCitation · doi-reference
The Him gene reveals a balance of inputs controlling muscle differentiation in Drosophila
10.1016/j.cub.2007.07.039 · ExternalCitation · doi-reference
Propylparaben impairs muscle development in zebrafish via the PI3K-mTOR pathway
10.1016/j.ecoenv.2025.118985 · ExternalCitation · doi-reference
Metabolic perturbations underlying the associations of endocrine-disrupting chemical mixtures with muscle mass and strength in adults: a repeated-measures study
10.1016/j.enceco.2025.08.019 · ExternalCitation · doi-reference
The mixed effect of endocrine-disrupting chemicals on biological age acceleration: unveiling the mechanism and potential intervention target
10.1016/j.envint.2024.108447 · ExternalCitation · doi-reference
Procymidone induces muscle atrophy and impaired myocyte fusion via the TNF-α/NF-κB/ROS pathway in developing zebrafish embryos
10.1016/j.envpol.2026.127760 · ExternalCitation · doi-reference
Natural flavonoid luteolin promotes the differentiation of porcine myoblasts through activation of PI3K/Akt/mTOR signaling
10.1016/j.fbio.2022.101766 · ExternalCitation · doi-reference
The oxidation of 2',7'-dichlorofluorescin to reactive oxygen species: a self-fulfilling prophesy?
10.1016/j.freeradbiomed.2005.10.042 · ExternalCitation · doi-reference
Mechanisms and functions of Nrf2 signaling in Drosophila
10.1016/j.freeradbiomed.2015.06.020 · ExternalCitation · doi-reference
Comparisons of lifespan and stress resistance between sexes in Drosophila melanogaster
10.1016/j.heliyon.2023.e18178 · ExternalCitation · doi-reference
Ginsenoside Rb1 and Rb2 upregulate Akt/mTOR signaling–mediated muscular hypertrophy and myoblast differentiation
10.1016/j.jgr.2019.01.007 · ExternalCitation · doi-reference
Antioxidant and anti-inflammatory activity through inhibition of NF-κB and sEH of some citrus peel and phytoconstituent characteristics
10.1016/j.jsps.2024.101959 · ExternalCitation · doi-reference
Hexavalent chromium inhibits myogenic differentiation and induces myotube atrophy
10.1016/j.taap.2023.116693 · ExternalCitation · doi-reference
A review on insoluble-bound phenolics in plant-based food matrix and their contribution to human health with future perspectives
10.1016/j.tifs.2020.09.029 · ExternalCitation · doi-reference
Nuclear receptors--a perspective from Drosophila
10.1038/nrg1581 · ExternalCitation · doi-reference
Diplazium esculentum (Retz.) Sw. reduces BACE-1 activities and amyloid peptides accumulation in Drosophila models of Alzheimer's disease
10.1038/s41598-021-03142-w · ExternalCitation · doi-reference
Pharmacokinetics of the citrus flavanone aglycones hesperetin and naringenin after single oral administration in human subjects
10.1038/sj.ejcn.1602543 · ExternalCitation · doi-reference
Naringin mitigates LPS-induced intestinal barrier injury in mice
10.1039/d2fo03586c · ExternalCitation · doi-reference
Myogenic differentiation is dependent on both the kinase function and the N-terminal sequence of Mammalian target of rapamycin
10.1074/jbc.m112285200 · ExternalCitation · doi-reference
Plasma kinetics and urinary excretion of the flavanones naringenin and hesperetin in humans after ingestion of orange juice and grapefruit juice
10.1093/jn/131.2.235 · ExternalCitation · doi-reference
In vitro effects of emerging bisphenols on myocyte differentiation and insulin responsiveness
10.1093/toxsci/kfaa130 · ExternalCitation · doi-reference
Inflammatory cytokines inhibit myogenic differentiation through activation of nuclear factor-κΒ
10.1096/fj.00-0463 · ExternalCitation · doi-reference
Sarcopenia: definition, epidemiology, and pathophysiology
10.11005/jbm.2013.20.1.1 · ExternalCitation · doi-reference
Drosophila estrogen-related receptor directs a transcriptional switch that supports adult glycolysis and lipogenesis
10.1101/gad.335281.119 · ExternalCitation · doi-reference
Valorization of pomelo (Citrus grandis Osbeck) peel: a review of current utilization, phytochemistry, bioactivities, and mechanisms of action
10.1111/1541-4337.12561 · ExternalCitation · doi-reference
Sexual dimorphism in the nutritional requirement for adult lifespan in Drosophila melanogaster
10.1111/acel.13120 · ExternalCitation · doi-reference
Supplementation of Citrus maxima peel powder prevented oxidative stress, fibrosis, and hepatic damage in carbon tetrachloride (CCl4) treated rats
10.1155/2015/598179 · ExternalCitation · doi-reference
Effects of curcuminoids identified in rhizomes of Curcuma longa on BACE-1 inhibitory and behavioral activity and lifespan of Alzheimer's disease Drosophila models
10.1186/1472-6882-14-88 · ExternalCitation · doi-reference
Cellular and molecular mechanisms of muscle atrophy
10.1242/dmm.010389 · ExternalCitation · doi-reference
Characterization of a Drosophila Alzheimer's disease model: pharmacological rescue of cognitive defects
10.1371/journal.pone.0020799 · ExternalCitation · doi-reference
Extracts of pomelo peels prevent high-fat diet-induced metabolic disorders in c57bl/6 mice through activating the PPARα and GLUT4 pathway
10.1371/journal.pone.0077915 · ExternalCitation · doi-reference
Mitohormesis: promoting health and lifespan by increased levels of Reactive Oxygen Species (ROS)
10.2203/dose-response.13-035.ristow · ExternalCitation · doi-reference
Obesogens: how they are identified and molecular mechanisms underlying their action
10.3389/fendo.2021.780888 · ExternalCitation · doi-reference
Castor oil plant (Ricinus communis L.) leaves improve dexamethasone-induced muscle atrophy via Nrf2 activation
10.3389/fphar.2022.891762 · ExternalCitation · doi-reference
Skeletal muscle wasting with disuse atrophy is multi-dimensional: the response and interaction of myonuclei, satellite cells and signaling pathways
10.3389/fphys.2014.00099 · ExternalCitation · doi-reference
Sarcopenic obesity: involvement of oxidative stress and beneficial role of antioxidant flavonoids
10.3390/antiox12051063 · ExternalCitation · doi-reference
Effects of bisphenol A on oxidative stress in the Rat brain
10.3390/antiox9030240 · ExternalCitation · doi-reference
Analysis of phytonutrients, anti-mutagenic and chemopreventive effects of tropical fruit extracts
10.3390/foods10112600 · ExternalCitation · doi-reference
Signaling pathways that control muscle mass
10.3390/ijms21134759 · ExternalCitation · doi-reference
Endocrine-disrupting chemicals and their adverse effects on the endoplasmic reticulum
10.3390/ijms23031581 · ExternalCitation · doi-reference
Prevalence and mechanisms of skeletal muscle atrophy in metabolic conditions
10.3390/ijms24032973 · ExternalCitation · doi-reference
Ficus lindsayana leaf extract protects C2C12 Mouse myoblasts against the suppressive effects of Bisphenol-A on Myogenic differentiation
10.3390/ijms26020476 · ExternalCitation · doi-reference
Anoectochilus burmannicus extract rescues aging-related phenotypes in Drosophila susceptible to oxidative stress-induced senescence
10.3390/ijms26125694 · ExternalCitation · doi-reference
Sarcopenia: current insights into molecular mechanisms, diagnostics, and emerging interventional approaches
10.3390/ijms26146740 · ExternalCitation · doi-reference
In vitro phytotherapeutic properties of aqueous extracted Adenia viridiflora craib. towards civilization diseases
10.3390/molecules26041082 · ExternalCitation · doi-reference
Optimization of phytochemical-rich citrus maxima Albedo extract using response surface methodology
10.3390/molecules28104121 · ExternalCitation · doi-reference
Monotropein improves dexamethasone-induced muscle atrophy via the AKT/mTOR/FOXO3a signaling pathways
10.3390/nu14091859 · ExternalCitation · doi-reference
Nephrotoxicity of phthalates: a review based on epidemiological and toxicological evidence
10.3390/toxics13110947 · ExternalCitation · doi-reference
How body burden from exposure to endocrine disruptors effects accelerated aging?
10.35208/ert.1334434 · ExternalCitation · doi-reference
