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References from Association of protein signature of fine particulate matter with MASLD: the underlying pathways and Mendelian randomization analysis. Local targets link to admitted publications; unresolved targets remain external evidence.
The rising global burden of MASLD and other metabolic diseases (2000-2021)
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Mechanisms and disease consequences of nonalcoholic fatty liver disease
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Integrating the environmental and genetic architectures of aging and mortality
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Environmental risk factors for liver cancer and nonalcoholic fatty liver disease
10.1007/s40471-019-0183-2 · 2019 · External reference
Air pollution deaths attributable to fossil fuels: observational and modelling study
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Mapping the association between environmental pollutants and steatotic liver disease: a systematic review and meta-analysis
10.1016/j.envres.2025.122623 · 2025 · External reference
A proteo-transcriptomic map of non-alcoholic fatty liver disease signatures
10.1038/s42255-023-00775-1 · 2023 · External reference
Dissecting metabolic dysfunction- and alcohol-associated liver disease (MetALD) using proteomic and metabolomic profiles
10.1016/j.jhep.2025.05.026 · 2025 · External reference
Subacute PM2.5 exposure induces hepatic insulin resistance through inflammation and oxidative stress
2025 · External reference
Air pollution and systemic inflammation in patients with suspected OSA living in an urban residential area
10.1016/j.chest.2020.05.596 · 2020 · External reference
Association of metabolic signatures of air pollution with MASLD: observational and mendelian randomization study
10.1016/j.jhep.2024.09.033 · 2025 · External reference
Large-scale plasma proteomics uncovers novel targets linking ambient air pollution and depression
10.1038/s41380-025-02953-x · 2025 · External reference
Plasma proteome mediates the associations between air pollution exposure and disease risk
2026 · External reference
Revisiting biomarker discovery by plasmaproteomics
10.15252/msb.20156297 · 2017 · External reference
Noninvasive proteomic biomarkers for alcohol-related liver disease
10.1038/s41591-022-01850-y · 2022 · External reference
Multi-omics profiling reveals altered mitochondrial metabolism in adipose tissue from patients with metabolic dysfunction-associated steatohepatitis
10.1016/j.ebiom.2024.105532 · 2025 · External reference
Mechanisms of NAFLD development and therapeutic strategies
10.1038/s41591-018-0104-9 · 2018 · External reference
Plasma proteome profiling discovers novel proteins associated with non-alcoholic fatty liver disease
10.15252/msb.20188793 · 2019 · External reference
Plasma proteomic associations with genetics and health in the UK Biobank
10.1038/s41586-023-06592-6 · 2023 · External reference
Proteomic signature of dementia risk in type 2 diabetes
2025 · External reference
Alzheimer's Disease polygenic risk, the plasma proteome, and dementia incidence among UK older adults
10.1007/s11357-024-01413-8 · 2025 · External reference
Quality control and removal of technical variation of NMR metabolic biomarker data in ∼120,000 UK Biobank participants
10.1038/s41597-023-01949-y · 2023 · External reference
Exposure to air pollution during pre-hypertension and subsequent hypertension, cardiovascular disease, and death: a trajectory analysis of the UK biobank cohort
10.1289/ehp10967 · 2023 · External reference
Disconnection of network hubs and cognitive impairment after traumatic brain injury
10.1093/brain/awv075 · 2015 · External reference
Metabolic signature of healthy lifestyle and risk of rheumatoid arthritis: observational and mendelian randomization study
10.1016/j.ajcnut.2023.04.034 · 2023 · External reference
The Mediterranean diet, plasma metabolome, and cardiovascular disease risk
10.1093/eurheartj/ehaa209 · 2020 · External reference
Steroid receptor coactivator-1 facilitates METTL3-mediated m6A modification by coactivating NF-kappaB and promotes the malignant progression of glioblastoma
10.1038/s41388-025-03494-x · 2025 · External reference
Biomass fuel induces neuroinflammation and neurodegeneration via the astrocyte-microglia IL-17A/IL-17RA pathway
10.1016/j.jhazmat.2025.138569 · 2025 · External reference
Prolonged PM2.5 exposure elevates risk of oxidative stress-driven nonalcoholic fatty liver disease by triggering increase of dyslipidemia
10.1016/j.freeradbiomed.2018.11.016 · 2019 · External reference
Chemokines and chemokine receptors in the development of NAFLD
10.1007/978-981-10-8684-7_4 · 2018 · External reference
Integrated profiling of adiponectin and cytokine signaling pathways in high-fat diet-induced MASLD reveals early markers of disease progression
10.1038/s41598-025-02001-2 · 2025 · External reference
Hepatic recruitment of macrophages promotes nonalcoholic steatohepatitis through CCR2
10.1152/ajpgi.00365.2011 · 2012 · External reference
CC chemokine ligand 3 deficiency ameliorates diet-induced steatohepatitis by regulating liver macrophage recruitment and M1/M2 status in mice
10.1016/j.metabol.2021.154914 · 2021 · External reference
Interleukin-22 ameliorates neutrophil-driven nonalcoholic steatohepatitis through multiple targets
10.1002/hep.31031 · 2020 · External reference
Associations of exposure to fine particulate matter mass and constituents with systemic inflammation: a cross-sectional study of urban older adults in China
10.1021/acs.est.1c04488 · 2022 · External reference
The acute effects of fine particulate matter constituents on blood inflammation and coagulation
10.1021/acs.est.7b00312 · 2017 · External reference
10.20944/preprints202205.0252.v1
10.20944/preprints202205.0252.v1 · External reference
MMP-9 deficiency shelters endothelial PECAM-1 expression and enhances regeneration of steatotic livers after ischemia and reperfusion injury
10.1016/j.jhep.2013.12.022 · 2014 · External reference
Genome-wide enhancer-gene regulatory maps of liver reveal novel regulatory mechanisms underlying NAFLD pathogenesis
10.1186/s12864-025-11668-w · 2025 · External reference
Exposure to ambient air pollution and elevated blood levels of gamma-glutamyl transferase in a large Austrian cohort
10.1016/j.scitotenv.2023.163658 · 2023 · External reference
Hesperidin ameliorates hepatocyte cell cycle disruption, apoptosis, and necroptosis in mice with nonalcoholic fatty liver disease via the VEGFA-PI3K/AKT pathway
10.1016/j.intimp.2025.115304 · 2025 · External reference
Inhibition of DDR1 potentiates carbon ion radiotherapy by promoting ferroptosis and immunogenic death in head and neck squamous cell carcinoma
10.1186/s12967-025-07062-5 · 2025 · External reference
CD28 ligation in the absence of TCR stimulation up-regulates IL-17A and pro-inflammatory cytokines in relapsing-remitting multiple sclerosis T lymphocytes
10.1016/j.imlet.2013.12.020 · 2014 · External reference
Examination of the causal role of immune cells in non-alcoholic fatty liver disease by a bidirectional Mendelian randomization study
2025 · External reference
Analysis of the genetic relationship between atherosclerosis and non-alcoholic fatty liver disease through biological interaction networks
10.3390/ijms24044124 · 2023 · External reference
Granulocyte colony stimulating factor treatment in non-alcoholic fatty liver disease: beyond marrow cell mobilization
10.18632/oncotarget.18967 · 2017 · External reference
Increased Tim-3 expression alleviates liver injury by regulating macrophage activation in MCD-induced NASH mice
10.1038/s41423-018-0032-0 · 2019 · External reference
Disturbance of mitochondrial functions caused by N-acetylglutamate and N-acetylmethionine in brain of adolescent rats: potential relevance in aminoacylase 1 deficiency
10.1016/j.neuint.2023.105631 · 2023 · External reference
Proteomic profiling of plasma to uncover novel intervention targets and prognostic biomarkers for chronic liver diseases
10.1111/dom.70696 · 2026 · External reference
Identification and multicentric validation of soluble CDCP1 as a robust serological biomarker for risk stratification of NASH in obese Chinese
2023 · External reference
IKK-beta links inflammation to obesity-induced insulin resistance
10.1038/nm1185 · 2005 · External reference
The role of hepatic lipids in hepatic insulin resistance and type 2 diabetes
10.1038/nature13478 · 2014 · External reference
Nonalcoholic fatty liver disease as a nexus of metabolic and hepatic diseases
10.1016/j.cmet.2017.08.002 · 2018 · External reference
Metabolic regulation of the immune system in health and diseases: mechanisms and interventions
10.1038/s41392-024-01954-6 · 2024 · External reference
Non-alcoholic fatty liver disease and cardiovascular risk: pathophysiological mechanisms and implications
10.1016/j.jhep.2016.04.005 · 2016 · External reference
High-density lipoprotein modifications: a pathological consequence or cause of disease progression?
10.3390/biomedicines8120549 · 2020 · External reference
Neuregulin1 ameliorates metabolic dysfunction-associated fatty liver disease via the ERK/SIRT1 signaling pathways
10.1186/s12876-025-03632-5 · 2025 · External reference
The paraoxonase (PON) gene family in health, metabolic dysfunction-associated steatotic liver disease (MASLD) and other diseases
10.3390/ijms262211054 · 2025 · External reference
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10.1021/acssensors.0c01524 · External reference
PM2.5 induces liver fibrosis via triggering ROS-mediated mitophagy
10.1016/j.ecoenv.2018.08.050 · 2019 · External reference
Multi-omics reveals hypertrophy of adipose tissue and lipid metabolism disorder via mitochondria in young mice under real-ambient exposure to air pollution
10.3389/fphar.2023.1122615 · 2023 · External reference