Research graph
References from RNA engineering approaches to aid high-resolution structure determination of medium- to large-sized RNAs. Local targets link to admitted publications; unresolved targets remain external evidence.
Regulation of ferritin and transferrin receptor mRNAs
10.1016/s0021-9258(19)34036-0 · 1990 · External reference
Internal ribosome entry sites in cellular mRNAs: mystery of their existence
10.1074/jbc.r400041200 · 2005 · External reference
Non-template functions of viral RNA in picornavirus replication
10.1016/j.coviro.2011.09.005 · 2011 · External reference
Functional RNA elements in the dengue virus genome
10.3390/v3091739 · 2011 · External reference
Host-like RNA Elements Regulate Virus Translation
10.3390/v16030468 · 2024 · External reference
Structural and biophysical dissection of RNA conformational ensembles
10.1016/j.sbi.2024.102908 · 2024 · External reference
NMR of RNA - Structure and interactions
10.1016/j.sbi.2023.102532 · 2023 · External reference
NMR Spectroscopy of Large Functional RNAs: From Sample Preparation to Low-Gamma Detection
10.1002/cpnc.116 · 2020 · External reference
Thermodynamic characterization of naturally occurring RNA tetraloops
10.1261/rna.1773110 · 2010 · External reference
Insights into Stability and Folding of GNRA and UNCG Tetraloops Revealed by Microsecond Molecular Dynamics and Well-Tempered Metadynamics
10.1021/acs.jctc.5b00010 · 2015 · External reference
Free-energy landscape of a hyperstable RNA tetraloop
10.1073/pnas.1603154113 · 2016 · External reference
High-resolution reversible folding of hyperstable RNA tetraloops using molecular dynamics simulations
10.1073/pnas.1309392110 · 2013 · External reference
Characterizing the Folding Transition-State Ensembles in the Energy Landscape of an RNA Tetraloop
10.1021/acs.jcim.3c00426 · 2023 · External reference
Detailed analysis of the higher-order structure of 16S-like ribosomal ribonucleic acids
10.1128/mr.47.4.621-669.1983 · 1983 · External reference
Architecture of ribosomal RNA: constraints on the sequence of "tetra-loops"
10.1073/pnas.87.21.8467 · 1990 · External reference
The nature of preferred hairpin structures in 16S-like rRNA variable regions
10.1093/nar/20.8.1843 · 1992 · External reference
A network of heterogeneous hydrogen bonds in GNRA tetraloops
10.1006/jmbi.1996.0690 · 1996 · External reference
Common and distinctive features of GNRA tetraloops based on a GUAA tetraloop structure at 1.4 A resolution
10.1261/rna.2147803 · 2003 · External reference
High-resolution NMR study of a synthetic oligoribonucleotide with a tetranucleotide GAGA loop that is a substrate for the cytotoxic protein, ricin
10.1093/nar/21.24.5670 · 1993 · External reference
The crystal structure of UUCG tetraloop
10.1006/jmbi.2000.4204 · 2000 · External reference
Structure of an unusually stable RNA hairpin
10.1021/bi00227a016 · 1991 · External reference
Comparison between CUUG and UUCG tetraloops: thermodynamic stability and structural features analyzed by UV absorption and vibrational spectroscopy
10.1093/nar/29.19.4089 · 2001 · External reference
Solution structure of the CUUG hairpin loop: a novel RNA tetraloop motif
10.1021/bi00044a019 · 1995 · External reference
Identification and characterization of RNA pentaloop sequence families
2023 · External reference
The solution structure of coronaviral stem-loop 2 (SL2) reveals a canonical CUYG tetraloop fold
10.1016/j.febslet.2011.03.002 · 2011 · External reference
Mouse hepatitis virus stem-loop 2 adopts a uYNMG(U)a-like tetraloop structure that is highly functionally tolerant of base substitutions
10.1128/jvi.00915-09 · 2009 · External reference
Sequence- and structure-specific RNA processing by a CRISPR endonuclease
10.1126/science.1192272 · 2010 · External reference
Contribution of the closing base pair to exceptional stability in RNA tetraloops: roles for molecular mimicry and electrostatic factors
10.1021/ja900065e · 2009 · External reference
Identification and Characterization of New RNA Tetraloop Sequence Families
10.1021/acs.biochem.9b00535 · 2019 · External reference
Solution structure of the HIV-1 frameshift inducing stem-loop RNA
10.1093/nar/gkg654 · 2003 · External reference
Mapping the Universe of RNA Tetraloop Folds
10.1016/j.bpj.2017.06.011 · 2017 · External reference
Crystal structures of the SAM-III/S(MK) riboswitch reveal the SAM-dependent translation inhibition mechanism
10.1038/nsmb.1494 · 2008 · External reference
Model for an RNA tertiary interaction from the structure of an intermolecular complex between a GAAA tetraloop and an RNA helix
10.1038/372111a0 · 1994 · External reference
A loop-loop "kissing" complex is the essential part of the dimer linkage of genomic HIV-1 RNA
10.1073/pnas.93.11.5572 · 1996 · External reference
Structural Insights into RNA Dimerization: Motifs, Interfaces and Functions
10.3390/molecules25122881 · 2020 · External reference
Crystal structure of the ribonucleoprotein core of the signal recognition particle
10.1126/science.287.5456.1232 · 2000 · External reference
The crystal structure of the signal recognition particle in complex with its receptor
10.1126/science.1196473 · 2011 · External reference
Crystal structure of a group I ribozyme domain: principles of RNA packing
10.1126/science.273.5282.1678 · 1996 · External reference
A general module for RNA crystallization
10.1006/jmbi.1998.1789 · 1998 · External reference
New molecular engineering approaches for crystallographic studies of large RNAs
10.1016/j.sbi.2014.02.001 · 2014 · External reference
A simple and efficient method to reduce nontemplated nucleotide addition at the 3 terminus of RNAs transcribed by T7 RNA polymerase
10.1017/s1355838299991033 · 1999 · External reference
High-salt transcription of DNA cotethered with T7 RNA polymerase to beads generates increased yields of highly pure RNA
10.1016/j.jbc.2021.100999 · 2021 · External reference
A generic protocol for the expression and purification of recombinant RNA in Escherichia coli using a tRNA scaffold
10.1038/nprot.2009.67 · 2009 · External reference
Recombinant RNA technology: the tRNA scaffold
10.1038/nmeth1058 · 2007 · External reference
In Vivo Production of Small Recombinant RNAs Embedded in 5S rRNA-Derived Protective Scaffold
10.1007/978-1-0716-1499-0_7 · 2021 · External reference
In Vivo Production of Small Recombinant RNAs Embedded in a 5S rRNA-Derived Protective Scaffold
10.1007/978-1-4939-2730-2_5 · 2015 · External reference
Structural basis for cloverleaf RNA-initiated viral genome replication
10.1093/nar/gkad618 · 2023 · External reference
Structures of flavivirus RNA promoters suggest two binding modes with NS5 polymerase
10.1038/s41467-021-22846-1 · 2021 · External reference
Structure of HIV-1 RRE stem-loop II identifies two conformational states of the high-affinity Rev binding site
10.1038/s41467-024-48162-y · 2024 · External reference
Structure of coxsackievirus cloverleaf RNA and 3C(pro) dimer establishes the RNA-binding mechanism of enterovirus protease 3C(pro)
10.1126/sciadv.ads6862 · 2025 · External reference
ATP/ADP modulates gp16-pRNA conformational change in the Phi29 DNA packaging motor
10.1093/nar/gkz692 · 2019 · External reference
Zika virus: History, epidemiology, transmission, and clinical presentation
10.1016/j.jneuroim.2017.03.001 · 2017 · External reference
Flavivirus genome organization, expression, and replication
10.1146/annurev.mi.44.100190.003245 · 1990 · External reference
The methyltransferase domain of dengue virus protein NS5 ensures efficient RNA synthesis initiation and elongation by the polymerase domain
10.1093/nar/gku666 · 2014 · External reference
The structure of Zika virus NS5 reveals a conserved domain conformation
2017 · External reference
A novel in vitro replication system for Dengue virus. Initiation of RNA synthesis at the 3'-end of exogenous viral RNA templates requires 5'- and 3'-terminal complementary sequence motifs of the viral RNA
10.1074/jbc.274.47.33714 · 1999 · External reference
Interactions between the Dengue Virus Polymerase NS5 and Stem-Loop A
10.1128/jvi.00047-17 · 2017 · External reference
Interaction of West Nile virus NS5 with orthoflavivirus SLA RNAs and their effects on viral replication and inhibition
10.1128/jvi.02023-24 · 2025 · External reference
Structures of dengue virus RNA replicase complexes
10.1016/j.molcel.2023.06.023 · 2023 · External reference
The Role of the Stem-Loop A RNA Promoter in Flavivirus Replication
10.3390/v13061107 · 2021 · External reference
Ribosome Structure, Function, and Early Evolution
10.3390/ijms20010040 · 2018 · External reference
Ribosome engineering reveals the importance of 5S rRNA autonomy for ribosome assembly
10.1038/s41467-020-16694-8 · 2020 · External reference
5S Ribosomal RNA Database
10.1093/nar/30.1.176 · 2002 · External reference
rrnDB: documenting the number of rRNA and tRNA genes in bacteria and archaea
10.1093/nar/gkn689 · 2009 · External reference
The complete atomic structure of the large ribosomal subunit at 2.4 A resolution
10.1126/science.289.5481.905 · 2000 · External reference
A novel approach for monitoring genetically engineered microorganisms by using artificial, stable RNAs
10.1128/aem.61.10.3661-3666.1995 · 1995 · External reference
Engineered 5S ribosomal RNAs displaying aptamers recognizing vascular endothelial growth factor and malachite green
10.1002/jmr.917 · 2009 · External reference
Viral genome packaging machines: Structure and enzymology
10.1016/bs.enz.2021.09.006 · 2021 · External reference
Structure of the bacteriophage phi29 DNA packaging motor
10.1038/35047129 · 2000 · External reference
Defining molecular and domain boundaries in the bacteriophage phi29 DNA packaging motor
10.1016/j.str.2008.05.010 · 2008 · External reference
Boundary of pRNA functional domains and minimum pRNA sequence requirement for specific connector binding and DNA packaging of phage phi29
1997 · External reference
Structure and assembly of the essential RNA ring component of a viral DNA packaging motor
10.1073/pnas.1016690108 · 2011 · External reference
The pRNA-assisted RNA imaging scheme (pARIS): a generalizable scaffold-based approach to facilitate cryo-EM structure determination of small RNAs
10.3934/biophy.2026017 · 2026 · External reference
Circularly permuted viral pRNA active and specific in the packaging of bacteriophage phi 29 DNA
10.1006/viro.1995.1103 · 1995 · External reference
A viral genome packaging motor transitions between cyclic and helical symmetry to translocate dsDNA
10.1126/sciadv.abc1955 · 2021 · External reference
Structural assembly of the tailed bacteriophage varphi29
10.1038/s41467-019-10272-3 · 2019 · External reference
Scaffold-enabled high-resolution cryo-EM structure determination of RNA
10.1038/s41467-024-55699-5 · 2025 · External reference
A generalizable scaffold-based approach for structure determination of RNAs by cryo-EM
10.1093/nar/gkad784 · 2023 · External reference
Cryo-EM structures of full-length Tetrahymena ribozyme at 3.1 Å resolution
10.1038/s41586-021-03803-w · 2021 · External reference
RNA sample optimization for cryo-EM analysis
10.1038/s41596-024-01072-1 · 2025 · External reference
Scaffolds with optimized quaternary symmetry for de novo cryoEM structure determination of small RNAs
10.1038/s41592-026-03016-x · 2026 · External reference
Sub-3-A cryo-EM structure of RNA enabled by engineered homomeric self-assembly
10.1038/s41592-022-01455-w · 2022 · External reference