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References from Beyond uric acid: Allantoin reflects oxidative stress, disease burden, and cardiovascular comorbidities in hyperuricemia and gout. Local targets link to admitted publications; unresolved targets remain external evidence.
Two independent mutational events in the loss of urate oxidase during hominoid evolution
10.1007/bf00163854 · 1992 · External reference
Changes in serum urate and urate excretion with age
10.1053/j.ackd.2012.07.010 · 2012 · External reference
Xanthine oxidoreductase: a leading actor in cardiovascular disease drama
10.1016/j.redox.2021.102195 · 2021 · External reference
A genome-wide association analysis reveals new pathogenic pathways in gout
10.1038/s41588-024-01921-5 · 2024 · External reference
Role of NLRP3 inflammasome in the progression of NAFLD to NASH
10.1155/2016/6489012 · 2016 · External reference
Hyperuricemia-induced endothelial insulin resistance: the nitric oxide connection
10.1007/s00424-021-02606-2 · 2022 · External reference
Hyperuricemia and its related diseases: mechanisms and advances in therapy
10.1038/s41392-024-01916-y · 2024 · External reference
Alterations in lipidome profiles distinguish early-onset hyperuricemia, gout, and the effect of urate-lowering treatment
10.1186/s13075-023-03204-6 · 2023 · External reference
Ceramide-based risk score: a novel laboratory tool for cardiovascular risk stratification in hyperuricemia and gout
10.1016/j.vph.2025.107495 · 2025 · External reference
Detection of allantoin in clinical samples using hydrophilic liquid chromatography with stable isotope dilution negative ion tandem mass spectrometry
10.1016/j.jchromb.2012.02.009 · 2012 · External reference
Urate as a physiological substrate for myeloperoxidase: implications for hyperuricemia and inflammation
10.1074/jbc.m110.172460 · 2011 · External reference
Simultaneous determination of uric acid metabolites allantoin, 6-aminouracil, and triuret in human urine using liquid chromatography-mass spectrometry
10.1016/j.jchromb.2008.11.029 · 2009 · External reference
Allantoin as a marker of oxidative stress in human erythrocytes
2008 · External reference
Antioxidant status and purine bases in carotid artery plaque
10.1080/15257770802138608 · 2008 · External reference
Allantoin as an independent marker associated with carotid intima-media thickness in subclinical atherosclerosis
10.1590/1414-431x20187543 · 2018 · External reference
Serum but not cerebrospinal fluid levels of allantoin are increased in de novo Parkinson's disease
10.1038/s41531-023-00505-0 · 2023 · External reference
Plasma allantoin measurement by isocratic liquid chromatography with tandem mass spectrometry: method evaluation and application in oxidative stress biomonitoring
10.1016/j.cca.2013.06.015 · 2013 · External reference
Simultaneous measurement of allantoin and urate in plasma: analytical evaluation and potential clinical application in oxidant:antioxidant balance studies
10.1093/clinchem/45.6.901 · 1999 · External reference
Gout, Hyperuricaemia and Crystal-Associated Disease Network (G-CAN) consensus statement regarding labels and definitions of disease states of gout
10.1136/annrheumdis-2019-215933 · 2019 · External reference
Rapid and reliable HILIC-MS/MS method for monitoring allantoin as a biomarker of oxidative stress
10.1016/j.ab.2019.113509 · 2020 · External reference
Unresolved reference
External reference
New creatinine- and cystatin C–based equations to estimate GFR without race
10.1056/nejmoa2102953 · 2021 · External reference
Uric acid and oxidative stress
10.2174/138161205774913255 · 2005 · External reference
Action of biologically-relevant oxidizing species upon uric acid. Identification of uric acid oxidation products
10.1016/0009-2797(90)90006-9 · 1990 · External reference
Is allantoin in serum and urine a useful indicator of exercise-induced oxidative stress in humans?
10.1080/10715760000300241 · 2000 · External reference
Association of plasma uric acid with ischaemic heart disease and blood pressure: mendelian randomisation analysis of two large cohorts
10.1136/bmj.f4262 · 2013 · External reference
Effect of plasma uric acid on antioxidant capacity, oxidative stress, and insulin sensitivity in obese subjects
10.2337/db13-1396 · 2014 · External reference
Evaluation of allantoin levels as a new marker of oxidative stress in Behcet's disease
10.1080/03009740510026878 · 2006 · External reference
Monitoring of antioxidant properties of uric acid in humans for a consideration measuring of levels of allantoin in plasma by liquid chromatography
10.1016/j.cca.2005.09.002 · 2006 · External reference
Metabolomic profiling in the prediction of gestational diabetes mellitus
10.1007/s00125-015-3553-4 · 2015 · External reference
Metabonomic changes associated with atherosclerosis progression for LDLR(-/-) mice
10.1021/acs.jproteome.5b00032 · 2015 · External reference
Allantoin serves as a novel risk factor for the progression of MASLD
10.3390/antiox14050500 · 2025 · External reference
Oxidation of uric acid in rheumatoid arthritis: is allantoin a marker of oxidative stress?
10.1080/10715760410001694044 · 2004 · External reference
Myeloperoxidase and oxidative stress in rheumatoid arthritis
10.1093/rheumatology/kes193 · 2012 · External reference
A systematic review and meta-analysis of the association between uric acid and allantoin and rheumatoid arthritis
10.3390/antiox12081569 · 2023 · External reference
Myeloperoxidase and oxidation of uric acid in gout: implications for the clinical consequences of hyperuricaemia
10.1093/rheumatology/keu218 · 2014 · External reference
Hereditary xanthinuria is not so rare disorder of purine metabolism
10.1080/15257770.2018.1460478 · 2018 · External reference
Hyperuricemia and gout due to deficiency of hypoxanthine-guanine phosphoribosyltransferase in female carriers: new insight to differential diagnosis
10.1016/j.cca.2014.11.026 · 2015 · External reference
Clinical manifestations and molecular aspects of phosphoribosylpyrophosphate synthetase superactivity in females
10.1093/rheumatology/key041 · 2018 · External reference
Novel dysfunctional variant in ABCG2 as a cause of severe tophaceous gout: biochemical, molecular genetics and functional analysis
10.1093/rheumatology/kev350 · 2016 · External reference
Identification of two dysfunctional variants in the ABCG2 urate transporter associated with pediatric-onset of familial hyperuricemia and early-onset gout
10.3390/ijms22041935 · 2021 · External reference
Is uric acid a true antioxidant? Identification of uric acid oxidation products and their biological effects
10.1080/13510002.2025.2498105 · 2025 · External reference
Identification of the true product of the urate oxidase reaction
10.1021/ja970375t · 1997 · External reference
Structural and Functional Basis for (S)-Allantoin Formation in the Ureide Pathway
10.1074/jbc.m703211200 · 2007 · External reference