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References from Hybrid membrane-coated motors for atopic dermatitis therapy via pruritus relief and ILC2 suppression. Local targets link to admitted publications; unresolved targets remain external evidence.
Atopic dermatitis: an expanding therapeutic pipeline for a complex disease
10.1038/s41573-021-00266-6 · 2022 · External reference
Atopic dermatitis
10.1016/s0140-6736(15)00149-x · 2016 · External reference
The multidimensional burden of atopic dermatitis among adults: results from a large national survey
10.1001/jamadermatol.2022.1906 · 2022 · External reference
Translational implications of Th17-skewed inflammation due to genetic deficiency of a cadherin stress sensor
10.1172/jci144363 · 2022 · External reference
Atopic dermatitis
10.1038/s41572-018-0001-z · 2018 · External reference
Exogenous factors in the pathogenesis of atopic dermatitis: irritants and cutaneous infections
10.1111/cea.13820 · 2021 · External reference
Epidermal mechanical scratching-induced ROS exacerbates the itch-scratch cycle through TRPA1 activation on mast cells in atopic dermatitis
10.1016/j.jid.2024.12.026 · 2025 · External reference
New and emerging systemic treatments for atopic dermatitis
10.1007/s40265-020-01335-7 · 2020 · External reference
A basophil-neuronal axis promotes itch
10.1016/j.cell.2020.12.033 · 2021 · External reference
BATF acts as an essential regulator of IL-25-responsive migratory ILC2 cell fate and function
10.1126/sciimmunol.aay3994 · 2020 · External reference
Local inflammation enables a basophil-neuronal circuITCH in atopic dermatitis
10.1111/all.15026 · 2022 · External reference
The cytokine TGF-beta induces interleukin-31 expression from dermal dendritic cells to activate sensory neurons and stimulate wound itching
10.1016/j.immuni.2020.06.023 · 2020 · External reference
A sensory neuron-expressed IL-31 receptor mediates T helper cell-dependent itch: involvement of TRPV1 and TRPA1
10.1016/j.jaci.2013.10.048 · 2014 · External reference
CC chemokine ligand 2 upregulates the current density and expression of TRPV1 channels and Nav1.8 sodium channels in dorsal root ganglion neurons
10.1186/1742-2094-9-189 · 2012 · External reference
20-HETE mediated TRPV1 activation drives allokinesis via MrgprA3(+) neurons in chronic dermatitis
10.7150/thno.85214 · 2024 · External reference
Neuronal pentraxin 2 is required for facilitating excitatory synaptic inputs onto spinal neurons involved in pruriceptive transmission in a model of chronic itch
10.1038/s41467-022-30089-x · 2022 · External reference
Increased frequencies of basophils, type 2 innate lymphoid cells and Th2 cells in skin of patients with atopic dermatitis but not psoriasis
10.1016/j.jdermsci.2017.07.003 · 2017 · External reference
Skin microbe-dependent TSLP-ILC2 priming axis in early life is co-opted in allergic inflammation
10.1016/j.chom.2023.12.006 · 2024 · External reference
Barrier epithelial cells and the control of type 2 immunity
10.1016/j.immuni.2015.07.007 · 2015 · External reference
The IL1-like cytokine IL33 and its receptor ST2 are abnormally expressed in the affected skin and visceral organs of patients with systemic sclerosis
10.1136/ard.2009.119321 · 2010 · External reference
Effects of myeloid and plasmacytoid dendritic cells on ILC2s in patients with allergic rhinitis
10.1016/j.jaci.2019.11.029 · 2020 · External reference
Interferon gamma constrains type 2 lymphocyte niche boundaries during mixed inflammation
10.1016/j.immuni.2021.12.014 · 2022 · External reference
Understanding the key issues in the treatment of uncontrolled persistent asthma with type 2 inflammation
10.1183/13993003.03393-2020 · 2021 · External reference
The neuropeptide neuromedin U stimulates innate lymphoid cells and type 2 inflammation
10.1038/nature23676 · 2017 · External reference
The neuropeptide NMU amplifies ILC2-driven allergic lung inflammation
10.1038/nature24029 · 2017 · External reference
Neuropeptide regulation of non-redundant ILC2 responses at barrier surfaces
10.1038/s41586-022-05297-6 · 2022 · External reference
Substance P release by sensory neurons triggers dendritic cell migration and initiates the type-2 immune response to allergens
10.1016/j.immuni.2020.10.001 · 2020 · External reference
Tumour-derived extracellular vesicle membrane hybrid lipid nanovesicles enhance siRNA delivery by tumour-homing and intracellular freeway transportation
10.1002/jev2.12198 · 2022 · External reference
Multifunctional biomolecule nanostructures for cancer therapy
10.1038/s41578-021-00315-x · 2021 · External reference
A hybrid eukaryotic-prokaryotic nanoplatform with photothermal modality for enhanced antitumor vaccination
2020 · External reference
Peptidoglycan recognition proteins: modulators of the microbiome and inflammation
10.1038/nri3089 · 2011 · External reference
Immunogenic molecules associated with gut bacterial cell walls: chemical structures, immune-modulating functions, and mechanisms
10.1093/procel/pwad016 · 2023 · External reference
Cell membrane coated nanocarriers - an efficient biomimetic platform for targeted therapy
10.1016/j.jconrel.2020.09.012 · 2020 · External reference
Cucurbit-like polymersomes with aggregation-induced emission properties show enzyme-mediated motility
10.1021/acsnano.1c07343 · 2021 · External reference
Near-infrared laser-controlled nitric oxide-releasing gold nanostar/hollow polydopamine Janus nanoparticles for synergistic elimination of methicillin-resistant Staphylococcus aureus and wound healing
10.1016/j.actbio.2022.02.029 · 2022 · External reference
Metal ion and antibiotic co-loaded nanoparticles for combating methicillin-Rresistant Staphylococcus aureus-induced osteomyelitis
10.1021/acsnano.4c11956 · 2025 · External reference
Detailed profiling of protein Corona formed by polydopamine nanoparticles in human plasma
10.1021/acsami.4c21207 · 2025 · External reference
Polydopamine-induced multilevel engineering of regenerated silk fibroin fiber for photothermal conversion
2022 · External reference
Biomimetic self-guiding nanomotors boost active immunotherapy
10.1021/acsnano.5c12737 · 2025 · External reference
NIR-actuated ferroptosis nanomotor for enhanced tumor penetration and therapy
2024 · External reference
18beta-Glycyrrhetinic acid induces human HaCaT keratinocytes apoptosis through ROS-mediated PI3K-Akt signaling pathway and ameliorates IMQ-induced psoriasis-like skin lesions in mice
10.1186/s40360-020-00419-0 · 2020 · External reference
Beta-lactam antibiotics promote extracellular vesicle production of Staphylococcus aureus through ROS-mediated lipid metabolic reprogramming
10.1002/jev2.70077 · 2025 · External reference
Recent progress on asymmetric carbon- and silica-based nanomaterials: from synthetic strategies to their applications
10.1007/s40820-021-00789-y · 2022 · External reference
Innate lymphoid cells: major players in inflammatory diseases
10.1038/nri.2017.86 · 2017 · External reference
Barrier epithelial cells and the control of type 2 immunity
10.1016/j.immuni.2015.07.007 · 2015 · External reference
Multifunctional fucoidan-loaded Zn-MOF-encapsulated microneedles for MRSA-infected wound healing
10.1186/s12951-024-02398-4 · 2024 · External reference
Continuously released Zn(2+) in 3D-printed PLGA/beta-TCP/Zn scaffolds for bone defect repair by improving osteoinductive and anti-inflammatory properties
2023 · External reference
Innate lymphoid cell-based immunomodulatory hydrogel microspheres containing Cutibacterium acnes extracellular vesicles for the treatment of psoriasis
10.1016/j.actbio.2024.06.006 · 2024 · External reference
K25 (K25irs1), K26 (K25irs2), K27 (K25irs3), and K28 (K25irs4) represent the type I inner root sheath keratins of the human hair follicle
10.1038/sj.jid.5700494 · 2006 · External reference
Variant PADI3 in central centrifugal cicatricial alopecia
10.1056/nejmoa1816614 · 2019 · External reference
Cornulin, a marker of late epidermal differentiation, is down-regulated in eczema
10.1111/j.1398-9995.2008.01856.x · 2009 · External reference
Integrated bioinformatic analysis of gene expression profiling data to identify combinatorial biomarkers in inflammatory skin disease
10.1038/s41598-022-09840-3 · 2022 · External reference
Bioinformatic analysis of key pathways and genes involved in pediatric atopic dermatitis
2021 · External reference
Retnla overexpression attenuates allergic inflammation of the airway
10.1371/journal.pone.0112666 · 2014 · External reference
Air pollution and atopic dermatitis (AD): the impact of particulate matter (PM(10)) on an AD mouse-model
10.3390/ijms21176079 · 2020 · External reference
PI3 as a common hub gene linking atopic dermatitis and ulcerative colitis through immune cell recruitment mechanisms
10.2147/jir.s527507 · 2025 · External reference
Nitric oxide enhances keratinocyte cell migration by regulating rho GTPase via cGMP-PKG signalling
10.1371/journal.pone.0121551 · 2015 · External reference
Jingfang granules improve glucose metabolism disturbance and inflammation in mice with urticaria by up-regulating LKB1/AMPK/SIRT1 axis
10.1016/j.jep.2022.115913 · 2023 · External reference
Sensory TRP channels contribute differentially to skin inflammation and persistent itch
10.1038/s41467-017-01056-8 · 2017 · External reference
Toll-like receptor 7 mediates pruritus
10.1038/nn.2683 · 2010 · External reference
Exploring the skin microbiome in atopic dermatitis pathogenesis and disease modification
10.1016/j.jaci.2024.04.029 · 2024 · External reference
CERS1 is a biomarker of Staphylococcus aureus abundance and atopic dermatitis severity
10.1016/j.jaci.2024.09.017 · 2025 · External reference
Regulation of acetyl-CoA biosynthesis via an intertwined acetyl-CoA synthetase/acetyltransferase complex
10.1038/s41467-025-57842-2 · 2025 · External reference
Evolving concepts in NAD(+) metabolism
10.1016/j.cmet.2021.04.003 · 2021 · External reference
Blockade of glucose-6-phosphate dehydrogenase induces immunogenic cell death and accelerates immunotherapy
10.1136/jitc-2023-008441 · 2024 · External reference
Staphylococcus aureus and atopic dermatitis: a complex and evolving relationship
10.1016/j.tim.2017.11.008 · 2018 · External reference