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References from Dual-glycolipid engineered vaccine platform empowers delivery route customization to intercept tumor lung metastasis. Local targets link to admitted publications; unresolved targets remain external evidence.
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Lung-specific metastasis: the coevolution of tumor cells and lung microenvironment
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A noninvasive and highly effective inhaled nanovaccine based on natural polysaccharide for lung cancer treatment
2025 · External reference
Targeting metastasis
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Cancer vaccines: the next immunotherapy frontier
2022 · External reference
Antigen presentation in cancer: insights into tumour immunogenicity and immune evasion
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Mucosal imprinting of vaccine-induced CD8+ T cells is crucial to inhibit the growth of mucosal tumors
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Vaccination route matters for mucosal tumors
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Mucosal immunization with a pH-responsive nanoparticle vaccine induces protective CD8+ lung-resident memory T cells
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Tissue-resident memory T cells in tumor immunity and immunotherapy
10.1084/jem.20201605 · 2021 · External reference
Mucosal boosting enhances vaccine protection against SARS-CoV-2 in macaques
10.1038/s41586-023-06951-3 · 2024 · External reference
Emerging biological principles of metastasis
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Measuring kinetics and metastatic propensity of CTCs by blood exchange between mice
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Metastasis-initiating cells and ecosystems
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Intranasal prime-boost RNA vaccination elicits potent T cell response for lung cancer therapy
2025 · External reference
mRNA vaccines — a new era in vaccinology
10.1038/nrd.2017.243 · 2018 · External reference
mRNA vaccines: the most recent clinical applications of synthetic mRNA
10.1007/s12272-022-01381-7 · 2022 · External reference
Lipid nanoparticle (LNP) mediated mRNA delivery in neurodegenerative diseases
10.1016/j.jconrel.2025.113641 · 2025 · External reference
Polyethylene glycol (PEG): the nature, immunogenicity, and role in the hypersensitivity of PEGylated products
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Unlocking the therapeutic applicability of LNP-mRNA: chemistry, formulation, and clinical strategies
10.34133/research.0370 · 2024 · External reference
Anti-PEG antibodies boosted in humans by SARS-CoV-2 lipid nanoparticle mRNA vaccine
10.1021/acsnano.2c04543 · 2022 · External reference
The role of sialic acid-binding immunoglobulin-like-lectin-1 (siglec-1) in immunology and infectious disease
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Simultaneous dendritic cells targeting and effective endosomal escape enhance sialic acid-modified mRNA vaccine efficacy and reduce side effects
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A new application of monosialotetrahexosylganglioside in pharmaceutics: preparation of freeze-thaw-resistant coenzyme Q10 emulsions
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GM1 ganglioside: past studies and future potential
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PLGA nanoparticles surface decorated with the sialic acid, N-acetylneuraminic acid
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Synthesis, characterization and targeting potential of zidovudine loaded sialic acid conjugated-mannosylated poly(propyleneimine) dendrimers
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Golgi-endosome transport mediated by M6PR facilitates release of antisense oligonucleotides from endosomes
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Modulating intracellular pathways to improve non-viral delivery of RNA therapeutics
10.1016/j.addr.2021.114041 · 2022 · External reference
Sialic acid linkage in glycosphingolipids is a molecular correlate for trafficking and delivery of extracellular cargo
10.1111/tra.12100 · 2013 · External reference
Durable protective efficiency provide by mRNA vaccines require robust immune memory to antigens and weak immune memory to lipid nanoparticles
2024 · External reference
Unlocking the therapeutic applicability of LNP-mRNA: chemistry, formulation, and clinical strategies
10.34133/research.0370 · 2024 · External reference
IFN-α and IL-12 induce IL-18 receptor gene expression in human NK and T cells
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IL-12 and IL-23: master regulators of innate and adaptive immunity
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