Research graph
References from Material basis and MRGPRB3-associated mechanisms of dictamni cortex against pseudo-allergic reactions. Local targets link to admitted publications; unresolved targets remain external evidence.
MRGPRX2, drug pseudoallergies, inflammatory diseases, mechanisms and distinguishing MRGPRX2- and IgE/FcεRI-mediated events
10.1111/bcp.15845 · 2023 · External reference
Glucocorticoids and the risk of schizophrenia spectrum disorder in childhood and adolescence - a Danish nationwide study
10.1016/j.schres.2018.03.007 · 2018 · External reference
Positive and negative signals in mast cell activation
10.1016/j.it.2017.01.008 · 2017 · External reference
Diagnosis and management of anaphylaxis in precision medicine
10.1016/j.jaci.2017.06.012 · 2017 · External reference
Identification and characterization of quinoline alkaloids from the root bark of Dictamnus dasycarpus and their metabolites in rat plasma, urine and feces by UPLC/Qtrap-MS and UPLC/Q-TOF-MS
10.1016/j.jpba.2021.114229 · 2021 · External reference
Unresolved reference
2025 · External reference
Topical delivery of bioactive compounds from cortex dictamni alleviates atopic dermatitis-like lesion by inhibiting the activation of keratinocytes, macrophages, and basophils: dictamnine versus fraxinellone
2024 · External reference
Expression of Mas-related gene X2 on mast cells is upregulated in the skin of patients with severe chronic urticaria
10.1016/j.jaci.2014.05.004 · 2014 · External reference
Rapid identification, isolation, and evaluation on anti-neuroinflammatory activity of limonoids derivatives from the root bark of Dictamnus dasycarpus
10.1016/j.jpba.2021.114079 · 2021 · External reference
Mass spectrometry guided strategy based on characteristic fragment ions for tracking and separation of quinoline alkaloids in traditional Chinese medicine Bai Xian Pi
2018 · External reference
Mast cells and basophils are essential for allergies: mechanisms of allergic inflammation and a proposed procedure for diagnosis
10.1038/aps.2013.88 · 2013 · External reference
Neuroprotective effects of constituents of the root bark of Dictamnus dasycarpus in mouse hippocampal cells
10.1007/s12272-010-0818-9 · 2010 · External reference
Nonallergic hypersensitivity to nonsteroidal antiinflammatory drugs, angiotensin-converting enzyme inhibitors, radiocontrast media, local anesthetics, volume substitutes and medications used in general anesthesia
2009 · External reference
Therapeutic effects of combination using glucosamine plus tacrolimus (FK-506) on the development of atopic dermatitis-like skin lesions in NC/Nga mice
10.1111/j.1365-3083.2011.02659.x · 2012 · External reference
Fraxinellone inhibits lipopolysaccharide-induced inducible nitric oxide synthase and cyclooxygenase-2 expression by negatively regulating nuclear factor-kappa B in RAW 264.7 macrophages cells
10.1248/bpb.32.1062 · 2009 · External reference
Unlocking the Non-IgE-Mediated pseudo-allergic reaction puzzle with mas-related G-Protein coupled receptor member X2 (MRGPRX2)
10.3390/cells10051033 · 2021 · External reference
DOCK2 regulates MRGPRX2/B2-mediated mast cell degranulation and drug-induced anaphylaxis
10.1016/j.jaci.2023.01.029 · 2023 · External reference
Beyond allergies-updates on the role of mas-related G-Protein-Coupled receptor X2 in chronic urticaria and atopic dermatitis
10.3390/cells13030220 · 2024 · External reference
In vitro and in vivo antioxidative and hepatoprotective activity of aqueous extract of cortex dictamni
10.3748/wjg.v23.i16.2912 · 2017 · External reference
Comprehensive metabolic profiling of dictamni cortex in normal and rheumatoid arthritis rats using UHPLC-Q/TOF-MS/MS coupled with polygonal mass defect filtering
10.1016/j.jpba.2026.117596 · 2026 · External reference
Dictamnine is an effective anti-anaphylactoid compound acting via the MrgX2 receptor located on mast cells
10.1002/ptr.7007 · 2021 · External reference
Unresolved reference
2025 · External reference
Glucocorticoids: fuelling the fire of atherosclerosis or therapeutic extinguishers?
10.3390/ijms22147622 · 2021 · External reference
Identification of a mast-cell-specific receptor crucial for pseudo-allergic drug reactions
10.1038/nature14022 · 2015 · External reference
Quinoline, quinazoline and acridone alkaloids
10.1039/b104971m · 2002 · External reference
A comparative study of the anti-eczema effects and mechanisms of action of the major active compounds in phellodendron bark: phellodendrine, phellodendronone, and phellodendronone
2023 · External reference
Apoptosis of AGS human gastric adenocarcinoma cells by methanolic extract of dictamnus
2015 · External reference
Mas-related G protein-coupled Receptor-X2 (MRGPRX2) in drug hypersensitivity reactions
10.3389/fimmu.2018.03027 · 2018 · External reference
A connective tissue mast-cell-specific receptor detects bacterial quorum-sensing molecules and mediates antibacterial immunity
10.1016/j.chom.2019.06.003 · 2019 · External reference
The traditional uses, phytochemistry, pharmacology and toxicology of dictamnus dasycarpus: a review
10.1093/jpp/rgab141 · 2021 · External reference
Exploring the mechanism of dictamni cortex in treating eczema through liquid mass spectrometry combined with network pharmacology
2022 · External reference
Roles of mas-related G protein-coupled receptor X2 on mast cell-mediated host defense, pseudoallergic drug reactions, and chronic inflammatory diseases
10.1016/j.jaci.2016.04.051 · 2016 · External reference
Dictamnol, a new Trinor-Guaiane type sesquiterpene, from the roots of Dictamnus dasycarpus TURCZ
10.1248/cpb.41.923 · 1993 · External reference
GRK2 differentially regulates FcεRI and MRGPRB3-mediated responses in mast cells
10.3389/fimmu.2023.1155777 · 2023 · External reference
MRGPRX2-Mediated degranulation of human skin mast cells requires the operation of G(αi), G(αq), Ca++ channels, ERK1/2 and PI3K-Interconnection between early and late signaling
10.3390/cells11060953 · 2022 · External reference
Unresolved reference
2024 · External reference
Unresolved reference
2006 · External reference
Unresolved reference
2024 · External reference
SPME-GC-MS analysis of volatile oil components in dictamni cortex
2007 · External reference
Chemical composition analysis of volatile oil from dictamni cortex
2009 · External reference
Unresolved reference
2006 · External reference
Anti-atopic dermatitis effect of fraxinellone via inhibiting IL-31 in vivo and in vitro
10.1016/j.heliyon.2024.e35391 · 2024 · External reference
Eudesmane-Type sesquiterpene glycosides from Dictamnus dasycarpus turcz
2018 · External reference
Limonoids from Dictamnus dasycarpus protect against glutamate-induced toxicity in primary cultured rat cortical cells
10.1007/s12031-010-9333-1 · 2010 · External reference
MRGPRX2 mediates immediate-type pseudo-allergic reactions induced by iodine-containing iohexol
10.1016/j.biopha.2021.111323 · 2021 · External reference
Simultaneous determination of transdermal component content and transdermal characteristics of Fu Zheng and Fu Zhi Yang formulas based on UPLC-Q-Exactive Orbitrap-MS method.New traditional Chinese medicine drugs and clinical
2026 · External reference
