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References from Traditional Chinese Medicine for Graves' Disease: Clinical Efficacy, Pharmacological Mechanisms, and Challenges. Local targets link to admitted publications; unresolved targets remain external evidence.
Antithyroid drug regimen for treating Graves' hyperthyroidism
2003 · External reference
Insights into thymus development and viral thymic infections
10.3390/v11090836 · 2019 · External reference
[Thyroid dysfunction]
10.1007/s15006-016-7652-z · 2016 · External reference
Clinical study of Yiqi Xiaoying Decoction in treating hyperthyroidism due to Graves' disease with Qi and Yin deficiency pattern
2021 · External reference
Antithyroid Drug Side Effects in the Population and in Pregnancy
10.1210/jc.2015-4274 · 2016 · External reference
Graves' disease: Clinical manifestations, immune pathogenesis (cytokines and chemokines) and therapy
10.1016/j.beem.2020.101388 · 2020 · External reference
Autoimmune thyroid disorders
10.1016/j.autrev.2014.10.016 · 2015 · External reference
Graves' disease: Epidemiology, genetic and environmental risk factors and viruses
10.1016/j.beem.2020.101387 · 2020 · External reference
T cell subsets and thyroid-stimulating antibodies in patients with Graves' disease in clinical remission
10.1007/bf03348102 · 1986 · External reference
On the role of stasis-toxin in Graves' disease and the clinical intervention of Jiakangning on it
2015 · External reference
The nature of apoptosis in the thyroid and the role it may play in autoimmune thyroid disease
10.1089/105072501750159633 · 2001 · External reference
The regulatory T cell gene FOXP3 and genetic susceptibility to thyroid autoimmunity: an association analysis in Caucasian and Japanese cohorts
10.1016/j.jaut.2007.02.016 · 2007 · External reference
microRNA expressions in CD4+ and CD8+ T-cell subsets in autoimmune thyroid diseases
10.1055/s-0033-1361088 · 2014 · External reference
Cardiovascular Risk Reduction with Icosapent Ethyl for Hypertriglyceridemia
10.1056/nejmoa1812792 · 2019 · External reference
Unresolved reference
External reference
Psychiatric manifestations of Graves' hyperthyroidism: pathophysiology and treatment options
10.2165/00023210-200620110-00003 · 2006 · External reference
Th17 cells and the IL-23/IL-17 axis in the pathogenesis of periodontitis and immune-mediated inflammatory diseases
2019 · External reference
Clinical observation on the short-term efficacy and long-term recurrence of integrated traditional Chinese and Western medicine in treating Graves' disease
2011 · External reference
Efficacy observation of Sargassum and Kelp herb pair combined with methimazole in treating newly diagnosed Graves' disease
2020 · External reference
Clinical efficacy observation of Prunella vulgaris Oral Liquid combined with methimazole in treating Graves' disease patients with heart-liver fire excess pattern
2020 · External reference
Clinical observation of the efficacy of soothing the liver and clearing the heart method in treating Graves' disease with heart-liver fire excess pattern
2017 · External reference
Unresolved reference
External reference
Ophiopogon japonicus-A phytochemical, ethnomedicinal and pharmacological review
10.1016/j.jep.2016.01.037 · 2016 · External reference
Therapeutic observation of Diyu Shengbai Tablets on leukopenia caused by Graves' disease
2009 · External reference
Clinical study on Dang Gui Liu Huang Tang as adjuvant therapy for hyperthyroidism
2011 · External reference
Clinical study of the clearing heart and draining fire method in treating toxic diffuse goiter with heart-liver fire excess pattern
2011 · External reference
Thyroid-stimulating hormone receptor and its role in Graves' disease
10.1016/j.ymgme.2003.09.001 · 2003 · External reference
Research progress on the efficacy and safety of Dioscorea bulbifera L. in the treatment of Graves' disease
2024 · External reference
A retrospective study on the effect of Astragalus-based preparations on serum thyrotropin receptor antibody levels in patients with Graves' disease
2020 · External reference
Hyperthyroidism
10.1016/s0140-6736(16)00278-6 · 2016 · External reference
Value of Apoptotic, Antiapoptotic, and Cell Proliferation Markers in the Treatment of Graves' Disease
10.1155/2018/3171280 · 2018 · External reference
Stimulatory TSH-Receptor Antibodies and Oxidative Stress in Graves disease
10.1210/jc.2018-00509 · 2018 · External reference
Biosynthesis and Pharmacological Activities of Flavonoids, Triterpene Saponins and Polysaccharides Derived from Astragalus membranaceus
10.3390/molecules28135018 · 2023 · External reference
Clinical effect analysis of methimazole combined with tripterygium glycosides tablets in the treatment of hyperthyroidism
2017 · External reference
Efficacy observation of Dang Gui Shao Yao San in treating 40 cases of Graves' disease
2007 · External reference
Hormone- and antibody-mediated activation of the thyrotropin receptor
10.1038/s41586-022-05173-3 · 2022 · External reference
Thyroid autoantibodies
10.1136/jcp-2022-208290 · 2023 · External reference
Disturbed Th1 and Th2 balance in patients with Graves' disease
2016 · External reference
Adverse effects of radioactive iodine-131 treatment for differentiated thyroid carcinoma
10.1097/mnm.0000000000000132 · 2014 · External reference
Chemokines in thyroid autoimmunity
10.1016/j.beem.2023.101773 · 2023 · External reference
Clinical observation of Shugan Xiexin Decoction in treating patients with Graves' disease of heart-liver fire excess pattern
2020 · External reference
Efficacy of Yikang Pill combined with 131I in treating toxic diffuse goiter
2015 · External reference
Clinical observation of modified Dan Zhi Xiao Yao San in treating Graves' disease with liver fire excess pattern
2021 · External reference
Oxidative stress enhances the immune response to oxidatively modified catalase enzyme in patients with Graves' disease
10.1002/jcla.23051 · 2020 · External reference
Toxic effects of Tripterygium glycoside tablets on the reproductive system of male rats by metabolomics, cytotoxicity, and molecular docking
10.1016/j.phymed.2023.154813 · 2023 · External reference
Effect of Bailing Capsule combined with MMI on serum thyroid hormone levels and recurrence rate in patients with Graves' disease
2020 · External reference
The Th1 chemokine MIG in Graves' Disease: a narrative review of the literature
2019 · External reference
Association Between Gut Microbiota and Autoimmune Thyroid Disease: A Systematic Review and Meta-Analysis
10.3389/fendo.2021.774362 · 2021 · External reference
Unresolved reference
External reference
Clinical study of Chai Xia Ziyin Formula in treating Graves' disease
2008 · External reference
Clinical observation of modified Dan Zhi Xiao Yao San in treating Graves' disease with liver fire excess pattern
2016 · External reference
Efficacy observation of Prunella vulgaris Capsule combined with methimazole in treating Graves' disease with liver fire excess pattern
2018 · External reference
Graves' Disease Combined With Orthostatic Hypotension: A Two-Case Report
10.1093/milmed/usac031 · 2023 · External reference
The Potential Prebiotic Berberine Combined With Methimazole Improved the Therapeutic Effect of Graves' Disease Patients Through Regulating the Intestinal Microbiome
2021 · External reference
Characterizing the Interplay of Lymphocytes in Graves' Disease
10.3390/ijms24076835 · 2023 · External reference
Clinical observation of the efficacy of soothing the liver and clearing heat method in treating Graves' disease with heart-liver fire excess pattern
2014 · External reference
Clinical observation of Mei Shao Xiejian Drink in treating diffuse toxic goiter with liver fire excess pattern
2023 · External reference
GATA3 and the T-cell lineage: essential functions before and after T-helper-2-cell differentiation
10.1038/nri2476 · 2009 · External reference
Study on the efficacy and safety of Ziyin Jianghuo Sanjie Formula containing iodine-rich herbs in treating Graves' disease
2020 · External reference
Efficacy observation of Shen Qi Tablets in the treatment of patients with hyperthyroidism
2006 · External reference
Theoretical and clinical study on combined internal and external treatment for hyperthyroidism (Graves' disease)
2006 · External reference
Unresolved reference
External reference
Application of Jiuyi Shengbai Oral Liquid in 131I treatment of Graves' disease accompanied by leukopenia
2008 · External reference
Clinical observation of Chinese medicine Shimai Qingye combined with 131I therapy for hyperthyroidism
2005 · External reference
Clinical observation of Qinggan Jianpi Decoction in treating hyperthyroidism with liver hyperactivity and spleen deficiency pattern
2022 · External reference
LncRNA RUNX1-IT1 affects the differentiation of Th1 cells by regulating NrCAM transcription in Graves' disease
10.1080/15384101.2022.2034431 · 2022 · External reference
Long-term clinical efficacy study of Xiehuo Xiaoying Formula combined with methimazole in patients with hyperthyroidism due to Graves' disease at initial treatment stage presenting heart-liver fire excess pattern
2018 · External reference
Effect of Bailing Capsule on T lymphocyte subsets in patients with Graves' disease
2013 · External reference
Long-term efficacy of Xiehuo Xiaoying Formula combined with methimazole in the initial treatment of hyperthyroidism due to Graves' disease with heart-liver fire excess pattern
2022 · External reference
Consistency Between Thyrotropin Receptor Antibody (TRAb) and Thyroid-Stimulating Antibody (TSAb) Levels in Patients with Graves Disease
10.1093/labmed/lmac008 · 2022 · External reference
Impact of Caspase3/GSDME-Mediated Pyroptosis on Tumor Immune Microenvironment and Clinical Prognosis Across Multiple Cancers
10.2147/cmar.s492171 · 2024 · External reference
Efficacy of Ningying Formula combined with low-dose methimazole in the treatment of Graves' disease and its effect on pro-inflammatory cytokines in patients
2025 · External reference
Molecular Alteration Analysis of Human Gut Microbial Composition in Graves' disease Patients
10.7150/ijbs.24151 · 2018 · External reference
CD4+ cells in autoimmune thyroid disease
10.5603/ep.a2021.0076 · 2021 · External reference
Clinical observation of Qinggan Kaiyu Formula in treating Graves' disease with heart-liver fire excess pattern
2021 · External reference
Clinical observation of Huotan Jiangni Formula combined with MMI in treating Graves' disease
2018 · External reference
Progress of research into the pharmacological effect and clinical application of the traditional Chinese medicine Rehmanniae Radix
10.1016/j.biopha.2023.115809 · 2023 · External reference
Efficacy observation of Longmu Xiaoyao San in treating Graves' disease with heart-liver fire excess pattern
2019 · External reference
Single-cell omics reveal the mechanisms of traditional Chinese medicines
10.1016/j.phymed.2025.157204 · 2025 · External reference
Clinical study of Prunella vulgaris Granule combined with MMI tablets in treating patients with toxic diffuse goiter and hyperthyroidism
2023 · External reference
Hyperthyroidism: a comprehensive review
10.1111/j.1745-7599.1992.tb01105.x · 1992 · External reference
Management of Graves Thyroidal and Extrathyroidal Disease: An Update
10.1210/clinem/dgaa646 · 2020 · External reference
The impact of surgical volume on patient outcomes following thyroid surgery
10.1016/j.surg.2013.04.068 · 2013 · External reference
Clinical study on the effect of the soothing liver and clearing heat method on TGAb and TMAb in patients with hyperthyroidism of liver depression transforming into fire pattern
2012 · External reference
Etiopathogenesis of Graves' disease
2003 · External reference
Thyroid dysfunction: an autoimmune aspect
2015 · External reference
Antidepressant and anxiolytic potential of Citrus reticulata Blanco essential oil: a network pharmacology and animal model study
10.3389/fphar.2024.1359427 · 2024 · External reference
T follicular helper (TFH) cells in normal and dysregulated immune responses
10.1146/annurev.immunol.26.021607.090344 · 2008 · External reference
Thyroid-Gut-Axis: How Does the Microbiota Influence Thyroid Function?
10.3390/nu12061769 · 2020 · External reference
Pathogenesis of Graves' Disease Determined Using Single-Cell Sequencing with Thyroid Autoantigen Peptide Stimulation in B Cells
10.3390/cells14141102 · 2025 · External reference
Changes in conjunctival cytology and tear function tests with radioiodine treatment for hyperthyroidism
10.1007/s12149-013-0705-9 · 2013 · External reference
Clinical observation of modified Shengmai San in treating Graves' disease with Qi and Yin deficiency pattern and its effect on TRAb
2016 · External reference
Study on the difference between combined decoction and single decoction of Danggui Liuhuang Tang in treating hyperthyroidism with yin deficiency pattern based on network pharmacology and 16S rDNA sequencing
2023 · External reference
Inhibition of TSH/IGF-1 Receptor Crosstalk by Teprotumumab as a Treatment Modality of Thyroid Eye Disease
10.1210/clinem/dgab824 · 2022 · External reference
Therapeutic effectiveness of iodine-rich herbs in treating Graves' hyperthyroidism: a retrospective cohort study from a single center
10.3389/fendo.2025.1573617 · 2025 · External reference
Oxidative Stress in Graves Disease and Graves Orbitopathy
10.1159/000509615 · 2020 · External reference
Graves disease: latest understanding of pathogenesis and treatment options
10.1038/s41574-024-01016-5 · 2024 · External reference
Linsitinib inhibits IGF-1-induced cell proliferation and hyaluronic acid secretion by suppressing PI3K/Akt and ERK pathway in orbital fibroblasts from patients with thyroid-associated ophthalmopathy
10.1371/journal.pone.0311093 · 2024 · External reference
Aiolos promotes CXCR3 expression on Th1 cells via positive regulation of IFN-γ/STAT1 signaling
10.1172/jci.insight.180287 · 2024 · External reference
Network pharmacology study of Citrus reticulata and Pinellia ternata in the treatment of non-small cell lung cancer
10.14715/cmb/2021.67.4.2 · 2022 · External reference
Efficacy observation of integrated traditional Chinese and Western medicine in treating Graves' disease
2011 · External reference
Clinical observation of Sanjie Jiaxiao Decoction combined with low-dose MMI in treating toxic diffuse goiter
2015 · External reference
Unresolved reference
External reference
Comprehensive chemical profiling of the flowers of Citrus aurantium L. var. amara Engl. and uncovering the active ingredients of lipid lowering
10.1016/j.jpba.2022.114621 · 2022 · External reference
Clinical observation on the efficacy of treating patients with hyperthyroidism
2009 · External reference
Unresolved reference
External reference
Local injection of Curcuma phaeocaulis Oil in the treatment of Graves' disease
2008 · External reference
Clinical observation of modified Chaihu Shugan San in treating hyperthyroidism with heart-liver fire excess pattern
2017 · External reference
Clinical observation of integrated traditional Chinese and Western medicine in treating hyperthyroidism
2008 · External reference
UHPLC-Q-Exactive Orbitrap MS/MS-Based Untargeted Metabolomics and Molecular Networking Reveal the Differential Chemical Constituents of the Bulbs and Flowers of Fritillaria thunbergii
10.3390/molecules27206944 · 2022 · External reference
Atractylodes macrocephala Koidz. and Cuscuta chinensis Lam. extract relieves insulin resistance via PI3K/Akt signalling in diabetic Drosophila
10.1016/j.jtcme.2024.01.010 · 2024 · External reference
Ranunculus ternatus Thunb. alkaloids attenuate colorectal cancer metastasis through EMT suppression
10.1016/j.phymed.2025.156965 · 2025 · External reference
Meta-analysis of blood system adverse events of Tripterygium wilfordii
2015 · External reference
Clinical experience in the treatment of Graves' disease based on syndrome differentiation
2002 · External reference
Clinical efficacy of Chai Shao Er Zhi San in treating Graves' disease and its correlation with levels of TRAb, SOD, GSH-Px, and FFA
2021 · External reference
Clinical observation of Chai Shao Er Zhi San in treating Graves' disease
2019 · External reference
Clinical study of Yiqi Yangyin Formula in treating Graves' disease complicated with leukocytopenia
2010 · External reference
Successful intervention with Chinese herbal medicine for hyperthyroidism: Two case reports and a literature review
10.1016/j.explore.2020.10.007 · 2021 · External reference
Toosendanin-induced liver damage through irreparable DNA damage and autophagy flow blockade
10.1016/j.phymed.2025.156586 · 2025 · External reference
Efficacy analysis of Yikang Pill combined with 131I in treating hyperthyroidism due to Graves' disease with exophthalmos
2015 · External reference
Efficacy observation of Jiakuang Ling Capsules combined with reduced-dose 131I in treating hyperthyroidism due to Graves' disease
2016 · External reference
Clinical efficacy observation and mechanism exploration of Ziyin Jianghuo Sanjie Formula in treating newly diagnosed Graves' disease
2016 · External reference
Elucidating the pharmacological foundations and mechanisms of the Sihai Shuyu formula in treating Graves' disease through integrated serum metabolomics and network pharmacology with molecular docking techniques
2025 · External reference
Gender impact on the correlations between Graves' hyperthyroidism and hyperuricemia in Chinese
10.1007/s11845-018-1939-2 · 2019 · External reference
Clinical observation of Shenxi Capsules combined with methimazole in treating hyperthyroidism (Graves' disease) with Qi deficiency and blood stasis pattern
2021 · External reference
Therapeutic Efficacy and Mechanism of Sihai Shuyu Formula in Treating Graves' Disease with Qi Stagnation and Phlegm Coagulation Pattern
2025 · External reference
Observation on the role of Dan Zhi Xiao Yao San in the clinical treatment of hyperthyroidism in women of childbearing age
2022 · External reference
Clinical observation of Xiaoying Wuhai Pills combined with methimazole in treating toxic diffuse goiter
2018 · External reference
Distribution of active ingredients and quality control of Forsythia suspensa with AP-MALDI mass spectrometry imaging
10.1002/jms.5073 · 2024 · External reference
Observation of the clinical efficacy of Yingzhong Xiao Decoction in treating mild to moderate Graves' disease based on repeated-measures analysis of variance
2021 · External reference
The emerging role of mitochondria in the pharmacological and toxicological effects of Tripterygium wilfordii Hook F: functions, targets and new therapeutic applications
10.1186/s13020-025-01170-6 · 2025 · External reference
Unresolved reference
External reference
Efficacy observation of Jiakuang Ling Capsules combined with PTU in treating Graves' disease
2018 · External reference
Mechanism of large polar iridoids from Scrophularia ningpoensis in preventing and treating hyperthyroidism with yin deficiency and effulgent fire pattern based on urinary metabolomics and network pharmacology
2026 · External reference
Clinical study of Ruanjian Sanjie Capsules in treating toxic diffuse goiter
2007 · External reference
Determination and Pharmacokinetic Profiles of Four Active Components From Scrophularia ningpoensis Hemsl
2020 · External reference
Clinical study of Qinggan Xiexin Decoction in treating hyperthyroidism with heart-liver fire excess pattern
2011 · External reference
Clinical observation and exploration of immunological mechanism of Yingqi Ling in treating Graves' disease
2005 · External reference
The origins, function, and regulation of T follicular helper cells
10.1084/jem.20120994 · 2012 · External reference
The crosstalk between SPP1(+) macrophages and follicular helper T cells promotes the immune disorder of Graves' disease
10.1016/j.clim.2026.110712 · 2026 · External reference
Effectiveness and potential mechanism of Jiawei-Xiaoyao-San for hyperthyroidism: a systematic review
10.3389/fendo.2023.1241962 · 2023 · External reference
Clinical study of Cordyceps preparation in treating newly diagnosed Graves' disease
2010 · External reference
Diagnosis and classification of Graves' disease
10.1016/j.autrev.2014.01.013 · 2014 · External reference
Clinical study of Tripterygium Glycosides in treating refractory Graves' disease
2011 · External reference
Clinical observation on the toxicity-reducing and efficacy-enhancing effects of Jiakangning Capsules in Graves' disease
2017 · External reference
Identification of potential immunotherapeutic targets and prognostic biomarkers in Graves' disease using weighted gene co-expression network analysis
10.1016/j.heliyon.2024.e27175 · 2024 · External reference
The role of the immune system and cytokines involved in the pathogenesis of autoimmune thyroid disease (AITD)
10.5603/ep.2014.0021 · 2014 · External reference
Clinical study of Jiazhong Xiao Formula on goiter in Graves' disease
2007 · External reference
Apoptosis induced by FasL and TRAIL/Apo2L in the pathogenesis of thyroid diseases
10.1016/s1043-2760(01)00441-6 · 2001 · External reference
CD25+ cell depletion hastens the onset of severe disease in collagen-induced arthritis
10.1002/art.11063 · 2003 · External reference
Delineating the autoimmune mechanisms in Graves' disease
10.1007/s12026-012-8312-8 · 2012 · External reference
Regulatory effect of Shengmai Injection on Th1/Th2 cell balance in Graves' disease
2008 · External reference
Intrathyroidal CD4+ T lymphocytes express high levels of Fas and CD4+ CD8+ macrophages/dendritic cells express Fas ligand in autoimmune thyroid disease
2004 · External reference
Unresolved reference
External reference
Clinical study on 30 cases of toxic diffuse goiter with heart-liver fire excess pattern treated by Qinggan Yuying Decoction combined with MMI
2023 · External reference
The mechanisms of tripterygium glycosides-induced reproductive toxicity and detoxification strategies
10.1016/j.reprotox.2025.108830 · 2025 · External reference
Clinical characteristics of myeloperoxidase antineutrophil cytoplasmic antibody-associated vasculitis caused by antithyroid drugs
10.1210/jc.2008-2700 · 2009 · External reference
10.5603/ep.102336
10.5603/ep.102336 · 2025 · External reference
Generation of T follicular helper cells is mediated by interleukin-21 but independent of T helper 1, 2, or 17 cell lineages
10.1016/j.immuni.2008.05.009 · 2008 · External reference
Analysis of T cell receptor Vbeta diversity in peripheral CD4 and CD8 T lymphocytes in patients with autoimmune thyroid diseases
10.1111/j.1365-2249.2008.03842.x · 2009 · External reference
Hepatotoxicity and cutaneous reactions after antithyroid drug administration
10.1111/j.1365-2265.2012.04365.x · 2012 · External reference
The PRISMA 2020 statement: an updated guideline for reporting systematic reviews
10.1136/bmj.n71 · 2021 · External reference
Efficacy of Zini Jiakang Formula in treating Graves' disease with Yin deficiency and fire excess pattern and its effect on immune function
2023 · External reference
Clinical efficacy evaluation of Chai Shao Er Zhi San in Graves' disease with liver dysfunction and its effects on IGF-1 and ADA
2024 · External reference
Analysis of the therapeutic effect of 131I combined with Compound Jiakang Tablets on patients with Graves' disease
2019 · External reference
Increased percentage of L-selectin+ and ICAM-1+ peripheral blood CD4+/CD8+ T cells in active Graves' ophthalmopathy
10.2478/v10042-009-0020-4 · 2009 · External reference
Efficacy observation of Yikang Formula combined with methimazole in treating Graves' disease with heart-liver fire excess pattern
2021 · External reference
Clinical observation of Yingxie Formula in treating Graves' disease with diarrhea as the main manifestation
2020 · External reference
A review of traditional and current processing methods used to decrease the toxicity of the rhizome of Pinellia ternata in traditional Chinese medicine
10.1016/j.jep.2022.115696 · 2022 · External reference
Effect of Simia Pill combined with methimazole tablets on thyroid volume in patients with Graves' disease
2025 · External reference
Efficacy evaluation and mechanism exploration of external application of Jialiu San in treating Graves' disease
2023 · External reference
Exploring the medication rules of Professor Gao Tianshu in treating hyperthyroidism based on data mining
2024 · External reference
Th1 and Th2 serum cytokine profiles characterize patients with Hashimoto's thyroiditis (Th1) and Graves' disease (Th2)
10.1159/000078438 · 2004 · External reference
Cyperus rotundus L.: Traditional uses, phytochemistry, and pharmacological activities
10.1016/j.jep.2015.08.012 · 2015 · External reference
Current perspective on the pathogenesis of Graves' disease and ophthalmopathy
10.1210/er.2002-0020 · 2003 · External reference
Diagnosis and treatment of Graves' disease with particular emphasis on appropriate techniques in nuclear medicine
10.5603/nmr.2015.0026 · 2015 · External reference
Dendritic cells in Graves' disease
2015 · External reference
Frequencies of PD-1- positive T CD3+CD4+, T CD3+CD8+ and B CD19+ lymphocytes in female patients with Graves' disease and healthy controls- preliminary study
10.1016/j.mce.2017.03.006 · 2017 · External reference
Increased Circulating Th17 but Decreased CD4(+)Foxp3(+) Treg and CD19(+)CD1d(hi)CD5(+) Breg Subsets in New-Onset Graves' Disease
10.1155/2017/8431838 · 2017 · External reference
Efficacy of Yikang Pill in treating toxic diffuse goiter and its effects on autoantibodies and adipocytokines
2013 · External reference
Clinical observation of modified Tianwang Buxin Dan on hyperthyroidism (Graves' disease) complicated with insomnia and anxiety
2022 · External reference
Changes in Th9 and Th17 lymphocytes and functional cytokines and their relationship with thyroid-stimulating hormone receptor antibodies at different stages of graves' disease
10.3389/fimmu.2022.919681 · 2022 · External reference
Regulation of apoptosis in endocrine autoimmunity: insights from Hashimoto's thyroiditis and Graves' disease
10.1111/j.1749-6632.2002.tb04253.x · 2002 · External reference
[Graves' disease and bone metabolism]
2006 · External reference
Clinical study of Ziyin Xiaoying Formula in treating hyperthyroidism (Graves' disease) with liver-kidney Yin deficiency and toxin-damaging collaterals pattern
2017 · External reference
Clinical study of modified Zhizi Qinggan Tang in treating newly diagnosed hyperthyroidism with liver fire excess pattern
2013 · External reference
Risks of Iodine Excess
10.1210/endrev/bnae019 · 2024 · External reference
Efficacy of Huangqi Suanzaoren Tang in treating Graves' disease with hyperthyroidism and its effects on TCM syndrome score and immune function
2023 · External reference
Clinical observation of Xiaqin Kangying Formula combined with methimazole in the treatment of Graves' disease with phlegm-heat internal disturbance pattern
2024 · External reference
Graves' disease: a new era of pathophysiology-guided therapeutics
10.1210/clinem/dgag010 · 2026 · External reference
Effect of methimazole treatment on Th1, Th17, and Th22 lymphocytes in pediatric Graves' disease patients
10.3389/fimmu.2024.1431686 · 2024 · External reference
A brief history of Th17, the first major revision in the Th1/Th2 hypothesis of T cell-mediated tissue damage
10.1038/nm1551 · 2007 · External reference
Novel Insights into Causal Effects of Lipid and Lipid-Lowering Targets with Autoimmune Thyroid Disease: A Mendelian Randomization Study
10.2147/itt.s487319 · 2024 · External reference
Current Diagnosis and Management of Graves' Disease
2018 · External reference
Clinical study on the short-term and long-term efficacy of Yin Jia Dan in intervening Graves' disease with phlegm-fire stagnation pattern
2017 · External reference
Clinical study on Jiakuang Formula No.1 combined with methimazole in treating toxic diffuse goiter with heart-liver fire excess pattern
2025 · External reference
Clinical observation of Beimu Exiao Pills in treating Graves' disease with qi stagnation and phlegm obstruction pattern
2019 · External reference
Clinical observation of the efficacy of Yiqi Yangyin Qinggan Formula in treating Graves' disease with Yin deficiency and Yang excess pattern
2012 · External reference
Short-term efficacy of Yin Jia Dan in treating hyperthyroidism due to Graves' disease and its effect on long-term recurrence rate
2021 · External reference
Molecular mechanism through which Tripterygium hypoglaucum (Lévl.) Hutch alleviates psoriasis
10.1016/j.biopha.2024.117647 · 2024 · External reference
Comparative Effectiveness of Treatment Choices for Graves' Hyperthyroidism: A Historical Cohort Study
10.1089/thy.2016.0343 · 2017 · External reference
Comparative effectiveness of therapies for Graves' hyperthyroidism: a systematic review and network meta-analysis
10.1210/jc.2013-1954 · 2013 · External reference
Clinical observation of modified Baihe Dihuang Tang in treating Graves' disease with Yin deficiency and Yang hyperactivity syndrome
2024 · External reference
Clinical study on the immunomodulatory mechanism of Chaishao Erzhi Formula in regulating immune balance in Graves' disease
2025 · External reference
Efficacy observation of integrated traditional Chinese and Western medicine in treating Graves' disease
2005 · External reference
Effect of integrated traditional Chinese and Western medicine on immunological parameters in Graves' disease
2009 · External reference
Observation and clinical study on the efficacy of Yingqi Ling on Graves' disease and its intervention on T lymphocyte subsets
2009 · External reference
Effect of Sanying Formula on serum cytokines in newly diagnosed hyperthyroidism due to Graves' disease
2017 · External reference
Clinical observation of Sanjie Xiaoying Tang in treating toxic diffuse goiter
2020 · External reference
CD8(+) T cell-based immunotherapy: Promising frontier in human diseases
10.1016/j.bcp.2025.116909 · 2025 · External reference
STAT3 Hyper-IgE Syndrome-an Update and Unanswered Questions
10.1007/s10875-021-01051-1 · 2021 · External reference
Association between polymorphism within interleukin related genes and Graves' disease: a meta-analysis of 22 case-control studies
10.18632/oncotarget.20114 · 2017 · External reference
The Usefulness of Thyroid Antibodies in the Diagnostic Approach to Autoimmune Thyroid Disease
2023 · External reference
Pathogenic Th17 and Th22 cells are increased in patients with autoimmune thyroid disorders
10.1007/s12020-017-1361-y · 2017 · External reference
Professor Li Saimei‘s experience in treating hyperthyroidism
2007 · External reference
Changes of T cell subsets after treatment with Astragalus membranaceus Injection for hyperthyroidism (Graves' disease)
2001 · External reference
Effect of Shen Xian Yiqi Zhuyang Decoction on thyroid autoantibody levels in patients with Graves' disease
2011 · External reference
Unresolved reference
External reference
Clinical observation of Jiakuang Formula No.2 in treating hyperthyroidism of Yin deficiency and Yang hyperactivity syndrome
2024 · External reference
Professor Dong Zhenhua's experience in the treatment of hyperthyroidism
2014 · External reference
Chemical Identity of Interaction of Protein with Reactive Metabolite of Diosbulbin B In Vitro and In Vivo
10.3390/toxins9080249 · 2017 · External reference
Active Compounds, Targets, and Mechanisms of Salvia miltiorrhiza Bunge in Treating Interstitial Cystitis/Bladder Pain Syndrome
10.1002/iid3.70173 · 2025 · External reference
Clinical observation of Shugan Jianpi Formula combined with MMI in treating Graves' disease
2013 · External reference
Clinical observation of the efficacy of Pingkang Xiaoying Decoction in treating Graves' disease and its effect on sFas
2017 · External reference
Tumor necrosis factor-related apoptosis-inducing ligand inhibits experimental autoimmune thyroiditis by the expansion of CD4+CD25+ regulatory T cells
10.1210/en.2008-1389 · 2009 · External reference
Clinical study of Qi Jing Pingkang Decoction in treating hyperthyroidism due to Graves' disease
2006 · External reference
Theoretical exploration and clinical study of the clearing heat and cooling blood method in treating newly diagnosed hyperthyroidism due to Graves' disease
2007 · External reference
Efficacy observation of integrated traditional Chinese and Western medicine in treating hyperthyroidism due to Graves' disease
2012 · External reference
Pathogenic role of Th17 cells in autoimmune thyroid disease and their underlying mechanisms
10.1016/j.beem.2023.101743 · 2023 · External reference
A Novel PDE4D Inhibitor BPN14770 Reverses Scopolamine-Induced Cognitive Deficits via cAMP/SIRT1/Akt/Bcl-2 Pathway
10.3389/fcell.2020.599389 · 2020 · External reference
Hepatotoxic Compounds and Mechanisms of Polygonum Multiflorum: A Narrative Review of Recent Advances
2026 · External reference
The management and metabolic characterization: hyperthyroidism and hypothyroidism
10.1016/j.npep.2022.102308 · 2023 · External reference
Using Network Pharmacology and Molecular Docking to Explore the Mechanism of Shan Ci Gu (Cremastra appendiculata) Against Non-Small Cell Lung Cancer
2021 · External reference
Effect of Prunella vulgaris Granule combined with methimazole on autoantibodies and cytokines in patients with Graves' disease
2017 · External reference
Graves' disease: Introduction, epidemiology, endogenous and environmental pathogenic factors
10.1016/j.ando.2018.09.002 · 2018 · External reference
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A Novel Monoclonal Antibody Degrades the Thyrotropin Receptor Autoantibodies in Graves' Disease
10.1016/j.eprac.2023.04.002 · 2023 · External reference
Effect of Huangqi on peripheral blood IL-1β, TNF-α, and antigen expression in mononuclear cells of patients with Graves' disease
2011 · External reference
Qualitative and quantitative analysis of Tripterygium hypoglaucum in Chinese herbal compound preparations
2022 · External reference
Study on protective effects and mechanisms of total glucosides of Paeony on Graves disease in BALB/c mice
2023 · External reference
Application of Prunella vulgaris Oral Liquid in the treatment of Graves' disease
2012 · External reference
Effect of Yingliu Mixture combined with MMI on thyroid function and related cytokines in patients with Graves' disease
2016 · External reference
CD4+ T cells and the Th1/Th2 imbalance are implicated in the pathogenesis of Graves' ophthalmopathy
2006 · External reference
Clinical observation of modified Yueju Wan in treating Graves' disease with phlegm-qi stagnation syndrome
2024 · External reference
Therapeutic potential of Scutellaria baicalensis Georgi in lung cancer therapy
10.1016/j.phymed.2021.153727 · 2022 · External reference
Clinical observation of integrated traditional Chinese and Western medicine in treating Graves' disease with liver dysfunction
2012 · External reference
Investigating the mechanism and efficacy material basis of Xiehuo Xiaoying decoction for treating Graves' disease via thyroid cell apoptosis based on proteomics and molecular docking techniques
10.1016/j.jep.2024.117753 · 2024 · External reference
Clinical observation of Dang Gui Liu Huang Tang in treating hyperthyroidism of Yin deficiency with effulgent fire pattern
2024 · External reference
Diosgenin From Dioscorea Nipponica Rhizoma Against Graves' Disease-On Network Pharmacology and Experimental Evaluation
2021 · External reference
Correlation between PGE1 and Graves' disease and clinical observation of the clearing liver and draining fire method on Graves' disease
2011 · External reference
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Effect of Xiehuo Yangyin Powder on Th1/Th2 cytokine balance in patients with Graves' disease
2011 · External reference
Clinical observation of Qingre Yangyin Decoction in treating Graves' disease with heart-liver fire excess pattern
2016 · External reference
Clinical study on integrated traditional Chinese and Western medicine in treating toxic diffuse goiter
2015 · External reference
Evaluation of the diagnostic performance of thyroid-stimulating immunoglobulin and thyrotropin receptor antibodies for Graves' disease
10.1002/jcla.24890 · 2023 · External reference
Peripherally induced tregs - role in immune homeostasis and autoimmunity
10.3389/fimmu.2013.00232 · 2013 · External reference
An updated view on transcription factor GATA3-mediated regulation of Th1 and Th2 cell differentiation
10.1093/intimm/dxr029 · 2011 · External reference
Clinical observation of Xiaoying Capsules combined with methimazole in treating toxic diffuse goiter
2021 · External reference
Rapid differential diagnosis of Graves' disease and painless thyroiditis using total T3/T4 ratio, TSH, and total alkaline phosphatase activity
10.1507/endocrj.52.29 · 2005 · External reference
Caspase-3 and apoptosis in experimental chronic renal scarring
10.1046/j.1523-1755.2001.00013.x · 2001 · External reference
Efficacy study of Yiyin Kangjia Formula combined with methimazole in the treatment of Graves' disease with hyperthyroidism
2024 · External reference
Ligustilide, a major bioactive component of Angelica sinensis, promotes bone formation via the GPR30/EGFR pathway
10.1038/s41598-019-43518-7 · 2019 · External reference
Clinical efficacy of Yingliu treatment for Graves disease
2015 · External reference
Clinical efficacy of Yingliu mixture combined with metimazole for treating diffuse goitre with hyperthyroidism and its impact on related cytokines
10.1080/13880209.2016.1260595 · 2017 · External reference
Clinical observation on the efficacy of Yingliu Mixture combined with methimazole in improving autoantibodies in diffuse toxic goiter
2014 · External reference
Effect of Prunella vulgaris Granule on inflammation and oxidative stress markers in Graves' disease
2023 · External reference
Possible molecular exploration of herbal pair Haizao-Kunbu in the treatment of Graves' disease by network pharmacology, molecular docking, and molecular dynamic analysis
10.3389/fendo.2023.1236549 · 2023 · External reference
Alteration of the intestinal flora may participate in the development of Graves' disease: a study conducted among the Han population in southwest China
10.1530/ec-19-0001 · 2019 · External reference
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Clinical efficacy observation of Danzhi Qinggan Tang in the treatment of Graves' disease with heart-liver fire excess pattern
2025 · External reference
Traditional Use, Pharmacology, Toxicology, and Quality Control of Species in Genus Bupleurum L
2013 · External reference
Clinical observation of Maocaogua Formula in the treatment of 168 cases of hyperthyroidism
2009 · External reference
Treatment of hyperthyroidism with Yin deficiency and fire excess pattern by Yin Jia Dan
2011 · External reference
Clinical study of Yiqi Yangyin Xiaoying Method in treating hyperthyroidism with Qi and Yin deficiency pattern
2011 · External reference
Puerarin inhibits inflammation and oxidative stress in female BALB/c mouse models of Graves' disease
10.21037/tp-23-370 · 2024 · External reference
Professor Chen Xiabo’s medication rule study on treating hyperthyroidism and preliminary exploration of pulse wave characteristics in hyperthyroidism patients
2024 · External reference
Effect of Jiakuang Ling combined with MMI on autoantibodies and inflammatory markers in Graves' disease
2020 · External reference
Exploration of medication rules and mechanisms of traditional Chinese medicine in treating hyperthyroidism of yin deficiency type based on network pharmacology and data mining
2025 · External reference
Clinical observation of JiaKangLing Tablets combined with Methimazole Tablets in treating toxic diffuse goiter
2025 · External reference
Integrating Network Pharmacology and Bioinformatics to Explore the Effects of Dangshen (Codonopsis pilosula) Against Hepatocellular Carcinoma: Validation Based on the Active Compound Luteolin
10.2147/dddt.s386941 · 2023 · External reference
Recent advances in CD8(+) regulatory T cell research
2018 · External reference
Effect of Bailing Capsule combined with MMI on serum thyroid hormones and recurrence rate in patients with Graves' disease
2020 · External reference
Low regulatory T cell and high IL-17 mRNA expression in a mouse Graves' disease model
10.1007/s40618-016-0575-9 · 2017 · External reference
Observation on the efficacy of Yikang Pill in patients with Graves' disease and changes in serum TRAb
2008 · External reference
Efficacy of modified Zini Haizao Xiaoying Decoction in treating mild to moderate Graves' disease and its impact on patients' quality of life
2023 · External reference
Clinical study on Qingge Pills combined with MMI in treating toxic diffuse goiter with liver fire excess pattern
2021 · External reference
Clinical study of Yingqi Ling on different TCM patterns of Graves' disease and its effect on immune balance
2007 · External reference
Effect of Yingqi Ling on serum IFN-γ and IL-4 in patients with Graves' disease
2008 · External reference
Efficacy evaluation of modified Erzhi Formula in treating toxic diffuse goiter with liver-kidney Yin deficiency pattern and its effects on TRAb and serum IGF-1
2022 · External reference
Effects of Xiehuo Xiaoying Formula on cellular immune function in patients with Graves' disease of heart-liver fire excess pattern
2024 · External reference
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Analysis of Yiqi Yangyin Formula in treating 88 cases of Graves' disease and changes in TRAb and TSH
2013 · External reference
Therapeutic effect of Yingqi Ling on toxic diffuse goiter and its mechanism exploration
2008 · External reference
Clinical study on Modified Huangqi Formula combined with methimazole on relevant antibodies in Graves' disease with Qi and Yin deficiency pattern
2018 · External reference
The double-edged sword of Dioscorea bulbifera L.: Recent advances in its pharmacological benefits and hepatotoxicity, and the quest for detoxification strategies
10.1016/j.jep.2026.121331 · 2026 · External reference
Mechanism of Prunella vulgaris L. and luteolin in restoring Tfh/Tfr balance and alleviating oxidative stress in Graves' disease
10.1016/j.phymed.2024.155818 · 2024 · External reference
Efficacy observation of integrated traditional Chinese and Western medicine in treating Graves' disease
2011 · External reference
Clinical efficacy of Jiakang Pingxiao Decoction combined with low-dose methimazole in the treatment of Graves' disease
2017 · External reference
Alterations and Mechanism of Gut Microbiota in Graves' Disease and Hashimoto's Thyroiditis
10.33073/pjm-2022-016 · 2022 · External reference
Potential roles and molecular mechanisms of bioactive ingredients in Curcumae Rhizoma against breast cancer
10.1016/j.phymed.2023.154810 · 2023 · External reference
Clinical study on Rougan Ziyin Formula combined with MMI in treating Graves' disease with Yin deficiency and Yang excess pattern
2022 · External reference
Traditional Uses, Chemical Constituents and Biological Activities of Plants from the Genus Sanguisorba L
10.1142/s0192415x17500136 · 2017 · External reference
A Global Regulatory Network for Dysregulated Gene Expression and Abnormal Metabolic Signaling in Immune Cells in the Microenvironment of Graves' Disease and Hashimoto's Thyroiditis
2022 · External reference
Effects of radioactive iodine combined with Salvia miltiorrhiza Injection on FT3, TSH, TRAb, and cardiac function indicators in patients with hyperthyroid heart disease
2019 · External reference
Clinical study of Qinggan Tang combined with methimazole in the treatment of hyperthyroidism
2007 · External reference
Efficacy of Wuyue Kangjia Pills as adjuvant therapy for Graves' disease and its effect on serum IGF-I level
2008 · External reference
Genetics, Epigenetics, Cellular Immunology, and Gut Microbiota: Emerging Links With Graves' Disease
2021 · External reference
Exploring the liver toxicity mechanism of Tripterygium wilfordii extract based on metabolomics, network pharmacological analysis and experimental validation
2025 · External reference
Efficacy observation of integrated traditional Chinese and Western medicine in treating 45 cases of Graves' disease
2007 · External reference
Clinical study of modified Shenmai Powder on hyperthyroidism (Graves' disease)
2010 · External reference
Single-Cell RNA Sequencing of Thyroid Tissues Reveals Pathogenesis of Graves' Disease
10.1002/advs.202508449 · 2026 · External reference
Efficacy observation of combined internal and external treatment in improving symptoms and signs of hyperthyroidism (Graves' disease)
2008 · External reference
Clinical study on the intervention of Erxia Xiaoying Decoction on Graves' disease
2008 · External reference
Effect of Sanjie Xiaoying Tang on thyroid size and TSH receptor antibodies in patients with Graves' disease
2017 · External reference