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References from Analysis of molecular events triggered by furanocoumarins in Psoralea corylifolia L. via reactive metabolites and protein adducts. Local targets link to admitted publications; unresolved targets remain external evidence.
Unresolved reference
2018 · External reference
Spatial analysis of renal acetaminophen metabolism and its modulation by 4-methylpyrazole with desi mass spectrometry imaging
10.1093/toxsci/kfae011 · 2024 · External reference
Lc-ms/ms-qtof screening and identification of phenolic compounds from australian grown herbs and their antioxidant potential
10.3390/antiox10111770 · 2021 · External reference
Cytochromes p450 catalyze the reduction of α,β-unsaturated aldehydes
10.1021/tx200080b · 2011 · External reference
Design of a nanozyme-based magnetic nanoplatform to enhance photodynamic therapy and immunotherapy
10.1016/j.jpha.2023.12.018 · 2024 · External reference
Ferulic acid prevents diosbulbin b-induced liver injury by inhibiting covalent modifications on proteins
10.1016/j.dmpk.2023.100507 · 2023 · External reference
Mechanistic study of cytochrome p450 enzyme-mediated cytotoxicity of psoralen and isopsoralen
10.1016/j.fct.2023.114011 · 2023 · External reference
Comparative study on chemical constituents of different processed products from psoralea corylifolia l. By qualitative and quantitative analysis
2019 · External reference
Unresolved reference
2025 · External reference
Myc on the path to cancer
10.1016/j.cell.2012.03.003 · 2012 · External reference
Activity-based protein profiling: recent advances in medicinal chemistry
10.1016/j.ejmech.2020.112151 · 2020 · External reference
Synthesis, structure, and tandem mass spectrometric characterization of the diastereomers of quinic acid
10.1021/acs.jafc.6b02472 · 2016 · External reference
Evaluation of processing based on the anti-osteoporosis compositions of psoralea coryfolia l
2013 · External reference
Exploring the underlying mechanisms of danshen-shanzha decoction on coronary heart disease: an integrated analysis combining pharmacoinformatics and experimental validation
2025 · External reference
Drug-protein adducts: chemistry, mechanisms of toxicity, and methods of characterization
10.1021/acs.chemrestox.6b00274 · 2016 · External reference
Coordination mechanism and bio-evidence: reactive γ-ketoenal intermediated hepatotoxicity of psoralen and isopsoralen based on computer approach and bioassay
10.3390/molecules22091451 · 2017 · External reference
Chemical composition analysis of psoraleae fructus alcohol extract by uplc-q-tof-ms and its mechanisms of promoting melanogenesis
2024 · External reference
Andrographis paniculata (burm. F.) Wall. Ex nees: a review of ethnobotany, phytochemistry, and pharmacology
10.1155/2014/274905 · 2014 · External reference
Characterization and identification of chemical components in traditional chinese medicine psoraleae fructus based on uhplc-q-tof-ms
2023 · External reference
Strategy for cysteine-targeting covalent inhibitors screening using in-house database based lc-ms/ms and drug repurposing
10.1016/j.jpha.2024.101045 · 2025 · External reference
The max-interacting transcription factor network
10.1016/j.semcancer.2006.07.009 · 2006 · External reference
Psoralen induces hepatotoxicity by covalently binding to glutathione-s-transferases and the hepatic cytochrome p450
10.1016/j.phymed.2022.154165 · 2022 · External reference
Activation of the nrf2/are signaling pathway protects against palmitic acid-induced renal tubular epithelial cell injury by ameliorating mitochondrial reactive oxygen species-mediated mitochondrial dysfunction
10.3389/fmed.2022.939149 · 2022 · External reference
Diminished function of cytotoxic t- and nk- cells in severe alcohol-associated hepatitis
10.20517/mtod.2022.13 · 2022 · External reference
Identification and quantification of flavonoids in yellow grain mutant of rice (oryza sativa l.)
10.1016/j.foodchem.2017.08.089 · 2018 · External reference
Unresolved reference
2019 · External reference
Protein targets of isoniazid-reactive metabolites in mouse liver in vivo
10.1021/acs.chemrestox.6b00098 · 2016 · External reference
Nontargeted identification of reactive metabolite protein adducts
10.1021/acs.analchem.6b04604 · 2017 · External reference
Identification of chemical constituents of qingjin yiqi granules and comparative study on pharmacokinetics of 23 main bioactive components in normal and lung-qi deficiency rats by uplc-ms/ms method
10.1016/j.jchromb.2023.123802 · 2023 · External reference
Identification of chemical and metabolic components in psoralea corylifolia l. By ultra-high performance liquid chromatography-tandem mass spectrometry
2010 · External reference
Quantitative analysis, pharmacokinetics and metabolomics study for the comprehensive characterization of the salt-processing mechanism of psoraleae fructus
10.1038/s41598-018-36908-w · 2019 · External reference
The interaction between polyphyllin i and sqle protein induces hepatotoxicity through srebp-2/hmgcr/sqle/lss pathway
10.1016/j.jpha.2022.11.005 · 2023 · External reference
Curcumin activates a ros/keap1/nrf2/mir-34a/b/c cascade to suppress colorectal cancer metastasis
10.1038/s41418-023-01178-1 · 2023 · External reference
Administration of psoralea corylifolia l. (Buguzhi) during pregnancy causes mild liver injury in mouse mothers and weaned offspring
10.1097/st9.0000000000000067 · 2025 · External reference
Chemical proteomics reveals sinomenine's anti-inflammatory mechanism through serum protein covalent modification
10.1186/s13020-026-01403-2 · 2026 · External reference
Quercetin inhibits the expression of myc and cyp2e1 and reduces oxidative stress in the myocardium of spontaneously hypertensive rats
2023 · External reference
The changes of hepatic bile acid synthesis and transport and bile acids profiles in isopsoralen-induced liver injury c57bl/6j mice
10.1080/13880209.2022.2116057 · 2022 · External reference
Cyp450: a crucial player in active ingredient biosynthesis in medicinal plants
10.1097/st9.0000000000000090 · 2025 · External reference
Lc/ms study of the diversity and distribution of pyrrolizidine alkaloids in crotalaria species growing in Colombia
10.1002/jssc.202000776 · 2020 · External reference
Chemical profiling of wu-tou decoction by uplc-q-tof-ms
10.1016/j.talanta.2013.09.054 · 2014 · External reference
Myc can induce dna breaks in vivo and in vitro independent of reactive oxygen species
10.1158/0008-5472.can-05-3115 · 2006 · External reference
Integrating network pharmacology, uplc-q-tof-ms and molecular docking to investigate the effect and mechanism of chuanxiong renshen decoction against Alzheimer'S disease
10.1186/s13020-022-00698-1 · 2022 · External reference
A systematic review on the safety of psoraleae fructus: potential risks, toxic characteristics, underlying mechanisms and detoxification methods
2022 · External reference
High-efficient discovering the potent anti-notum agents from herbal medicines for combating glucocorticoid-induced osteoporosis
10.1016/j.apsb.2025.06.004 · 2025 · External reference
Myc, metabolism, and cancer
10.1158/2159-8290.cd-15-0507 · 2015 · External reference
Spectrum-effect relationship combined with bioactivity evaluation to discover the main anxiolytic active components of baihe dihuang decoction
2024 · External reference
Identification and quantification of gingerols and related compounds in ginger dietary supplements using high-performance liquid chromatography-tandem mass spectrometry
10.1021/jf9020224 · 2009 · External reference
Functional characterization of cooperating mga mutations in runx1::runx1t1 acute myeloid leukemia
10.1038/s41375-024-02193-y · 2024 · External reference
Lignans from gnetum montanum markgr. F. Megalocarpua
10.1007/s10600-009-9325-y · 2010 · External reference
Chemical proteomics-based reactive metabolites and protein adducts: the new perspective on the metabolism of food furanocoumarins
2025 · External reference
Function-oriented mechanism discovery of coumarins from psoralea corylifolia l. In the treatment of ovariectomy-induced osteoporosis based on multi-omics analysis
10.1016/j.jep.2024.118130 · 2024 · External reference
Fangji huangqi decoction alleviates rheumatoid arthritis through regulating hif-1α mediated the angiogenesis and the balance between autophagy and apoptosis
10.1016/j.jep.2024.118061 · 2024 · External reference
Characterization of chemical composition from psoralea corylifolia l. Based on uhplc-q-orbitrap ms
2025 · External reference
Chemical constituent characterization and determination of quisqualis fructus based on uplc-q-tof-ms and hplc combined with fingerprint and chemometric analysis
2024 · External reference
Comprehensive study of the in vivo and in vitro metabolism of dietary isoflavone biochanin a based on uhplc-q-tof-ms/ms
10.1021/acs.jafc.9b05776 · 2019 · External reference
Psoralen and isopsoralen from psoraleae fructus aroused hepatotoxicity via induction of aryl hydrocarbon receptor-mediated cyp1a2 expression
10.1016/j.jep.2022.115577 · 2022 · External reference
Study on processing mechanism of psoralea corylifolia l. Based on uplc-q-tof/ms technology
2022 · External reference
Characterisation and classification of citri reticulatae pericarpium varieties based on uhplc-q-tof-ms/ms combined with multivariate statistical analyses
10.1002/pca.2812 · 2019 · External reference
Strategy for hepatotoxicity prediction induced by drug reactive metabolites using human liver microsome and online 2d-nano-lc-ms analysis
10.1021/acs.analchem.7b02684 · 2017 · External reference
Hepatotoxic evaluation of toosendanin via biomarker quantification and pathway mapping of large-scale chemical proteomics
10.1016/j.fct.2021.112257 · 2021 · External reference
