Research graph
References from Prevention of uterine fibroids: Molecular mechanisms and potential clinical application. Local targets link to admitted publications; unresolved targets remain external evidence.
Comprehensive review of uterine fibroids: developmental origin, pathogenesis, and treatment
10.1210/endrev/bnab039 · 2022 · External reference
Uterine fibroids: hiding in plain sight
2022 · External reference
The unmasking of novel unipotent stem cells in the mammary gland
10.1038/emboj.2011.415 · 2011 · External reference
Trop2 identifies a subpopulation of murine and human prostate basal cells with stem cell characteristics
10.1073/pnas.0811411106 · 2008 · External reference
Epigenomic and enhancer dysregulation in uterine leiomyomas
10.1093/humupd/dmac008 · 2022 · External reference
Loss of the repressor REST affects progesterone receptor function and promotes uterine leiomyoma pathogenesis
10.1073/pnas.2205524119 · 2022 · External reference
Aberrant R-loop-induced replication stress in MED12-mutant uterine fibroids
10.1038/s41598-022-10188-x · 2022 · External reference
Mediator kinase disruption in MED12-mutant uterine fibroids from hispanic women of South Texas
10.1210/jc.2018-00863 · 2018 · External reference
The role of endocrine-disrupting chemicals in uterine fibroid pathogenesis
10.1097/med.0000000000000578 · 2020 · External reference
Endocrine-disrupting chemicals and uterine fibroids
10.1016/j.fertnstert.2016.08.023 · 2016 · External reference
Environmental estrogens differentially engage the histone methyltransferase EZH2 to increase risk of uterine tumorigenesis
10.1158/1541-7786.mcr-11-0605 · 2012 · External reference
Xenoestrogen-induced regulation of EZH2 and histone methylation via estrogen receptor signaling to PI3K/AKT
10.1210/me.2009-0438 · 2010 · External reference
Interaction between genetic susceptibility and early-life environmental exposure determines tumor-suppressor-gene penetrance
10.1073/pnas.0503218102 · 2005 · External reference
Hair relaxer use and risk of uterine leiomyomata in African-American women
10.1093/aje/kwr351 · 2012 · External reference
Association of intrauterine and early-life exposures with diagnosis of uterine leiomyomata by 35 years of age in the Sister Study
10.1289/ehp.0901423 · 2010 · External reference
Uncovering evidence: associations between environmental contaminants and disparities in women’s health
10.3390/ijerph19031257 · 2022 · External reference
Racial/ethnic differences in women's experiences with symptomatic uterine fibroids: a qualitative assessment
10.1007/s40615-016-0216-1 · 2017 · External reference
Phthalate exposures and MicroRNA expression in uterine fibroids: the FORGE study
10.1177/2516865720904057 · 2020 · External reference
Effects of phthalate esters on human myometrial and fibroid cells: cell culture and NOD-SCID mouse data
10.1007/s43032-020-00341-0 · 2021 · External reference
Analysis of the in vitro effects of di-(2-ethylhexyl) phthalate exposure on human uterine leiomyoma cells
2018 · External reference
Association between urinary phthalate metabolites and risk of breast cancer and uterine leiomyoma
10.1016/j.reprotox.2017.09.009 · 2017 · External reference
Mono-(2-ethyl-5-hydroxyhexyl) phthalate promotes uterine leiomyoma cell survival through tryptophan-kynurenine-AHR pathway activation
10.1073/pnas.2208886119 · 2022 · External reference
The environmental injustice of beauty: framing chemical exposures from beauty products as a health disparities concern
10.1016/j.ajog.2017.07.020 · 2017 · External reference
Associations of exposure to phthalates and environmental phenols with gynecological disorders
10.1016/j.reprotox.2020.04.076 · 2020 · External reference
Association of environmental phenols with endometriosis and uterine leiomyoma: an analysis of NHANES, 2003–2006
10.1016/j.reprotox.2022.08.003 · 2022 · External reference
The influence of phenolic environmental estrogen on the transcriptome of uterine leiomyoma cells: a whole transcriptome profiling-based analysis
10.1016/j.ecoenv.2021.111945 · 2021 · External reference
Bisphenol A induces human uterine leiomyoma cell proliferation through membrane-associated ERα36 via nongenomic signaling pathways
10.1016/j.mce.2019.01.001 · 2019 · External reference
Effects of bisphenol A on uterine leiomyoma: In vitro and in vivo evaluation with mechanistic insights related to XBP1
10.1016/j.ecoenv.2022.114201 · 2022 · External reference
Nonpersistent endocrine disrupting chemicals and reproductive health of women
10.5468/ogs.2020.63.1.1 · 2020 · External reference
Perfluoroalkyl substances (PFAS) in drinking water and risk for polycystic ovarian syndrome, uterine leiomyoma, and endometriosis: a Swedish cohort study
10.1016/j.envint.2021.106819 · 2021 · External reference
Inhibition of MLL1 and HDAC activity reverses reprogrammed inflammatory components induced by developmental exposure to an endocrine disruptor (diethylstilbesterol) in myometrial stem cells
2021 · External reference
Increased pro-inflammatory signaling of stem cells correlating with the phenotype of uterine fibroids
2021 · External reference
Integrated multi-omics analyses of high-risk myometrial progenitor/stem cells: implication for uterine fibroid pathogenesis
2021 · External reference
Developmental reprogramming of pro-inflammatory pathway mediates adult onset of uterine fibroids
10.1016/j.fertnstert.2018.07.1053 · 2018 · External reference
Uterine fibroids: bridging genomic defects and chronic inflammation
10.1055/s-0037-1607240 · 2017 · External reference
Activin A in inflammation, tissue repair, and fibrosis: possible role as inflammatory and fibrotic mediator of uterine fibroid development and growth
10.1055/s-0037-1607265 · 2017 · External reference
Possible involvement of inflammatory/reparative processes in the development of uterine fibroids
10.1007/s00441-015-2324-3 · 2016 · External reference
Macrophages and immune responses in uterine fibroids
10.3390/cells10050982 · 2021 · External reference
Pro-inflammatory and immunosuppressive environment contributes to the development and progression of uterine fibroids
10.1016/j.fertnstert.2020.08.264 · 2020 · External reference
Human “at risk” myometrial stem cells exhibit an hyper-inflammatory phenotype
10.1016/j.fertnstert.2018.07.682 · 2018 · External reference
Racial/ethnic disparities in disease burden and costs related to exposure to endocrine-disrupting chemicals in the United States: an exploratory analysis
10.1016/j.jclinepi.2018.11.024 · 2019 · External reference
Epidemiology and risk factors of uterine fibroids
10.1016/j.bpobgyn.2017.09.004 · 2018 · External reference
Association between obesity and the risk of uterine fibroids: a systematic review and meta-analysis
10.1136/jech-2019-213364 · 2021 · External reference
Adipocytes enhance the proliferation of human leiomyoma cells via TNF-alpha proinflammatory cytokine
10.1177/1933719111408111 · 2011 · External reference
Adipocyte coculture induces a pro-inflammatory, fibrotic, angiogenic, and proliferative microenvironment in uterine leiomyoma cells
10.1016/j.bbadis.2022.166564 · 2023 · External reference
African genetic ancestry interacts with body mass index to modify risk for uterine fibroids
10.1371/journal.pgen.1006871 · 2017 · External reference
Effect of caloric restriction on gut permeability, inflammation markers, and fecal microbiota in obese women
10.1038/s41598-017-12109-9 · 2017 · External reference
Curcumin and piperine supplementation of obese mice under caloric restriction modulates body fat and interleukin-1beta
10.1186/s12986-018-0250-6 · 2018 · External reference
The extracellular matrix contributes to mechanotransduction in uterine fibroids
10.1155/2014/783289 · 2014 · External reference
Biology of the extracellular matrix: an overview
10.1097/ijg.0000000000000108 · 2014 · External reference
Latent TGF-beta structure and activation
10.1038/nature10152 · 2011 · External reference
Role of transforming growth factor beta in uterine fibroid biology
10.3390/ijms18112435 · 2017 · External reference
The impact of the extracellular matrix on inflammation
10.1038/nri2852 · 2010 · External reference
Cellular mechanotransduction: from tension to function
10.3389/fphys.2018.00824 · 2018 · External reference
Integrin-mediated mechanotransduction
10.1083/jcb.201609037 · 2016 · External reference
Extracellular matrix in uterine leiomyoma pathogenesis: a potential target for future therapeutics
10.1093/humupd/dmx032 · 2018 · External reference
Dynamic reciprocity between cells and their microenvironment in reproduction
10.1095/biolreprod.114.121368 · 2015 · External reference
ESCRT III repairs nuclear envelope ruptures during cell migration to limit DNA damage and cell death
10.1126/science.aad7611 · 2016 · External reference
TGF-B and early-life exposure to endocrine-disrupting chemicals impair nucleotide excision repair in eker rat myometrial stem cells
10.1016/j.fertnstert.2022.08.647 · 2022 · External reference
Evidence of selection as a cause for racial disparities in fibroproliferative disease
10.1371/journal.pone.0182791 · 2017 · External reference
Pleiotropic effects of immune responses explain variation in the prevalence of fibroproliferative diseases
10.1371/journal.pgen.1005568 · 2015 · External reference
Transcriptomics analysis shows profound ethnic differences in at risk pre-fibroid myometrium
10.1016/j.fertnstert.2021.07.040 · 2021 · External reference
Enhancing primary care and preventive services through Interprofessional practice and education
10.1186/s13584-020-00371-8 · 2020 · External reference
Health Care industry insights: why the use of preventive services is still low
10.5888/pcd16.180625 · 2019 · External reference
Fibroids: yet another example of disparity in health?
10.1186/s12916-022-02528-5 · 2022 · External reference
Ultrasound-confirmed, age-specific uterine leiomyoma incidence in a cohort of black individuals
10.1097/aog.0000000000004997 · 2022 · External reference
Unresolved reference
2023 · External reference
Burden, Prevalence, and treatment of uterine fibroids: a survey of U.S. women
10.1089/jwh.2018.7076 · 2018 · External reference
In vivo breast tumor detection using transient elastography
10.1016/s0301-5629(03)00978-5 · 2003 · External reference
Ultrasound elastography: the new frontier in direct measurement of muscle stiffness
10.1016/j.apmr.2014.07.007 · 2014 · External reference
Ultrasound elastography for musculoskeletal applications
10.1259/bjr/93042867 · 2012 · External reference
Diagnosing deep endometriosis using transvaginal elastosonography
10.1007/s43032-019-00108-2 · 2020 · External reference
The benefit of transvaginal elastography in detecting deep endometriosis: a feasibility study
2023 · External reference
The management of chronic hepatitis C: 2018 guideline update from the Canadian Association for the Study of the Liver
10.1503/cmaj.170453 · 2018 · External reference
EFSUMB guidelines and recommendations on the clinical use of ultrasound elastography. Part 2: clinical applications
10.1055/s-0033-1335375 · 2013 · External reference
Imaging for uterine myomas and adenomyosis
10.1016/j.jmig.2013.11.011 · 2014 · External reference
Importance of transvaginal elastography in the diagnosis of uterine fibroids and adenomyosis
2016 · External reference
Transvaginal ultrasound shear wave elastography for the evaluation of benign uterine pathologies: a prospective pilot study
10.1002/jum.14676 · 2019 · External reference
Value of ultrasound shear wave elastography in the diagnosis of adenomyosis
10.1177/1742271x16673677 · 2016 · External reference
A comparison of shear wave elastography between normal myometrium, uterine fibroids, and adenomyosis: a cross-sectional study
2022 · External reference
MRI for adenomyosis: a pictorial review
10.1007/s13244-017-0576-z · 2017 · External reference
Effects of epigallocatechin gallate-enriched green tea extract capsules in uterine myomas: results of an observational study
10.1007/s00404-020-05907-6 · 2021 · External reference
Uterine fibroids treatment: do we have new valid alternative? Experiencing the combination of vitamin D plus epigallocatechin gallate in childbearing age affected women
2021 · External reference
Dynamic and quasi-static mechanical testing for characterization of the viscoelastic properties of human uterine tissue
10.1016/j.jbiomech.2015.05.013 · 2015 · External reference
Characterization of tissue biomechanics and mechanical signaling in uterine leiomyoma
10.1016/j.matbio.2011.09.001 · 2012 · External reference
Transvaginal elastosonography as an imaging technique for diagnosing adenomyosis
10.1177/1933719117750752 · 2018 · External reference
Uterine fibroids: correlations between MRI appearance and stiffness via magnetic resonance elastography
10.1007/s00261-017-1314-1 · 2018 · External reference
Injectable Clostridium histolyticum collagenase as a potential treatment for uterine fibroids
10.1177/1933719114553449 · 2014 · External reference
Evidence of biomechanical and collagen heterogeneity in uterine fibroids
10.1371/journal.pone.0215646 · 2019 · External reference
Treatment of uterine fibroid symptoms with relugolix combination therapy
10.1056/nejmoa2008283 · 2021 · External reference
Feasibility of imaging and treatment monitoring of breast lesions with three-dimensional shear wave elastography
2017 · External reference
MR-guided focused ultrasound for uterine fibroids: a preliminary study of relationship between the treatment outcomes and factors of mr images including elastography
10.2463/mrms.tn.2017-0103 · 2019 · External reference
