Research graph
References from Immunosenescence and cancer. Local targets link to admitted publications; unresolved targets remain external evidence.
Cancer immunoediting: from immunosurveillance to tumor escape
10.1038/ni1102-991 · 2002 · External reference
Do autochthonous tumors interfere with effector T cell responses?
10.1016/j.semcancer.2007.06.007 · 2007 · External reference
The flip side of immune surveillance: immune dependency
10.1111/j.1600-065x.2008.00609.x · 2008 · External reference
The inflammatory micro-environment in tumor progression: the role of tumor-associated macrophages
10.1016/j.critrevonc.2007.07.004 · 2008 · External reference
Polarized immune responses differentially regulate cancer development
10.1111/j.1600-065x.2008.00600.x · 2008 · External reference
Immunity to methylcholanthrene-induced tumours in inbred rats following atrophy and regression of the implanted tumours
10.1038/bjc.1955.70 · 1955 · External reference
Adaptive immunity maintains occult cancer in an equilibrium state
10.1038/nature06309 · 2007 · External reference
Contribution of the PD-L1/PD-1 pathway to T-cell exhaustion: an update on implications for chronic infections and tumor evasion
10.1007/s00262-006-0272-1 · 2007 · External reference
10.1186/1742-4933-5-11 · 2008 · Admitted local publication
Toll-like receptor 4-dependent contribution of the immune system to anticancer chemotherapy and radiotherapy
10.1038/nm1622 · 2007 · External reference
DCVax-Brain and DC vaccines in the treatment of GBM
10.1517/13543780902841951 · 2009 · External reference
Safety and immunological efficacy of a DNA vaccine encoding prostatic acid phosphatase in patients with stage D0 prostate cancer
10.1200/jco.2008.19.9968 · 2009 · External reference
Vaccination strategies in patients with renal cell carcinoma
10.1007/s00262-009-0706-7 · 2009 · External reference
Biomarkers of human immunosenescence: impact of Cytomegalovirus infection
10.1016/j.coi.2009.05.012 · 2009 · External reference
Immunosenescence and vaccine failure in the elderly
10.1007/bf03324904 · 2009 · External reference
Tumor-induced modulation of dendritic cell function
10.1016/j.cytogfr.2007.10.008 · 2008 · External reference
Decline of T cell-related immune functions in cancer patients and an attempt to restore them through infusion of activated autologous T cells
10.1016/j.mad.2008.05.001 · 2009 · External reference
Cytomegalovirus and human immunosenescence
10.1002/rmv.598 · 2009 · External reference
Socioeconomic disparities in the seroprevalence of cytomegalovirus infection in the US population: NHANES III
10.1017/s0950268808000551 · 2009 · External reference
Role of cytomegalovirus in the T cell changes seen in elderly individuals
10.1006/clim.1998.4638 · 1999 · External reference
Cytomegalovirus-seropositivity has a profound influence on the magnitude of major lymphoid subsets within healthy individuals
10.1111/j.1365-2249.2008.03785.x · 2009 · External reference
T-regulatory cell modulation: the future of cancer immunotherapy?
10.1038/sj.bjc.6605040 · 2009 · External reference
The number of human peripheral blood CD4+ CD25high regulatory T cells increases with age
10.1111/j.1365-2249.2005.02798.x · 2005 · External reference
Higher frequency of regulatory T cells in the elderly and increased suppressive activity in neurodegeneration
10.1016/j.jneuroim.2007.05.011 · 2007 · External reference
Functional regulatory T cells accumulate in aged hosts and promote chronic infectious disease reactivation
10.4049/jimmunol.181.3.1835 · 2008 · External reference
CD4+CD25+ T regulatory cells inhibit cytotoxic activity of CTL and NK cells in humans-impact of immunosenescence
10.1016/j.clim.2006.02.002 · 2006 · External reference
Aging and human CD4(+) regulatory T cells
10.1016/j.mad.2009.06.003 · 2009 · External reference
Functional assay for human CD4+CD25+ Treg cells reveals an age-dependent loss of suppressive activity
10.1002/jnr.10766 · 2003 · External reference
Myeloid-derived suppressor cells as regulators of the immune system
10.1038/nri2506 · 2009 · External reference
Age-related increase of tumor susceptibility is associated with myeloid-derived suppressor cell mediated suppression of T cell cytotoxicity in recombinant inbred BXD12 mice
10.1016/j.mad.2007.10.003 · 2007 · External reference
Myeloid-derived suppressor cells down-regulate L-selectin expression on CD4+ and CD8+ T cells
10.4049/jimmunol.0804253 · 2009 · External reference
Conditions that diminish myeloid-derived suppressor cell activities stimulate cross-protective immunity
10.1128/iai.00759-08 · 2008 · External reference
Immunosenescence and cancer vaccines
10.1007/s00262-009-0665-z · 2009 · External reference
Impact of aging on cancer immunity and immunotherapy
10.1007/s00262-009-0743-2 · 2009 · External reference
Aging and the dendritic cell system: implications for cancer
10.1016/j.critrevonc.2007.03.002 · 2007 · External reference
Mechanisms of murine dendritic cell antitumor dysfunction in aging
10.1007/s00262-008-0636-9 · 2009 · External reference
The significance of OX40 and OX40L to T-cell biology and immune disease
10.1111/j.1600-065x.2009.00766.x · 2009 · External reference
The effect of aging on OX40 agonist-mediated cancer immunotherapy
10.1007/s00262-009-0687-6 · 2009 · External reference
Use of CD40L immunoconjugates to overcome the defective immune response to vaccines for infections and cancer in the aged
10.1007/s00262-009-0718-3 · 2009 · External reference
Cancer, aging and immunotherapy: lessons learned from animal models
10.1007/s00262-009-0677-8 · 2009 · External reference
Human T-cell clones in long-term culture as a model of immunosenescence
10.1111/j.1600-065x.1997.tb01025.x · 1997 · External reference
Clonal expansions in acute EBV infection are detectable in the CD8 and not the CD4 subset and persist with a variable CD45 phenotype
10.4049/jimmunol.165.10.5729 · 2000 · External reference
The flow cytometric analysis of telomere length in antigen-specific CD8+ T cells during acute Epstein-Barr virus infection
10.1182/blood.v97.3.700 · 2001 · External reference
Longitudinal studies of clonally expanded CD8 T cells reveal a repertoire shrinkage predicting mortality and an increased number of dysfunctional cytomegalovirus-specific T cells in the very elderly
10.4049/jimmunol.176.4.2645 · 2006 · External reference
Gene expression changes in long-term culture of T-cell clones: genomic effects of chronic antigenic stress in aging and immunosenescence
10.1111/j.1474-9726.2007.00269.x · 2007 · External reference
SELDI-TOF-MS ProteinChip array profiling of T-cell clones propagated in long-term culture identifies human profilin-1 as a potential bio-marker of immunosenescence
10.1186/1477-5956-5-7 · 2007 · External reference
High frequencies of functionally impaired cytokeratin 18-specific CD8+ T cells in healthy HLA-A2+ donors
10.1002/eji.200526207 · 2005 · External reference
under revision. Simultaneous infiltration of polyfunctional effector and suppressor T cells into renal cell carcinomas
10.1158/0008-5472.can-09-0852 · 2009 · External reference
Increase in tumour-infiltrating lymphocytes with regulatory T cell immunophenotypes and reduced zeta-chain expression in nasopharyngeal carcinoma patients
10.1111/j.1365-2249.2008.03793.x · 2009 · External reference
Follicular lymphoma B cells induce the conversion of conventional CD4+ T cells to T-regulatory cells
10.1002/ijc.23881 · 2009 · External reference
Tumor-derived TGF-beta mediates conversion of CD4+Foxp3+ regulatory T cells in a murine model of pancreas cancer
10.1097/cji.0b013e318189f13c · 2009 · External reference
Tumor-specific regulatory T cells in cancer patients
10.1016/j.humimm.2008.02.005 · 2008 · External reference
Increased programmed death-1+ tumor-infiltrating lymphocytes in classical Hodgkin lymphoma substantiate reduced overall survival
10.1016/j.humpath.2009.03.025 · 2009 · External reference
High numbers of tumor-infiltrating programmed cell death 1-positive regulatory lymphocytes are associated with improved overall survival in follicular lymphoma
10.1200/jco.2008.18.0513 · 2009 · External reference
Are regulatory T-cells linked with aging?
10.1016/j.exger.2006.01.008 · 2006 · External reference
Hypoxia controls CD4+CD25+ regulatory T-cell homeostasis via hypoxia-inducible factor-1alpha. Eur
2008 · External reference
Immune impairment in patients with terminal cancers: influence of cancer treatments and cytomegalovirus infection
2009 · External reference
Impact of Cytomegalovirus infection on immune signatures in cancer patients
2009 · External reference
Cytomegalovirus seropositivity is significantly associated with mycosis fungoides and Sezary syndrome
10.1182/blood-2002-07-2247 · 2003 · External reference
Cytomegalovirus seroprevalence is not higher in patients with mycosis fungoides/Sezary syndrome
10.1182/blood.v107.3.1241.1241 · 2006 · External reference
Frequency and clinical significance of human beta-herpesviruses in cervical samples from Italian women
10.1002/jmv.21054 · 2008 · External reference
Association of human beta-herpesviruses with the development of cervical cancer: bystanders or cofactors
10.1136/jcp.54.1.48 · 2001 · External reference
Relationship between viral factors, axillary lymph node status and survival in breast cancer
10.1007/s00432-006-0141-5 · 2007 · External reference
Cytomegalovirus, Epstein-Barr virus and risk of breast cancer before age 40 years: a case-control study
10.1038/sj.bjc.6601822 · 2004 · External reference