Research graph
References from Follow-Up after adjuvanT CDK4/6i Use in oldeR brEst cancer patients - aspects on geriatric screening, toxicities, and quality of life (FUTURE): A prospective observational cohort study. Local targets link to admitted publications; unresolved targets remain external evidence.
Unresolved reference
External reference
Enrollment of elderly patients in clinical trials for cancer drug registration: a 7-year experience by the US Food and Drug Administration
10.1200/jco.2004.02.175 · 2004 · External reference
FDA analysis of enrollment of older adults in clinical trials for cancer drug registration: a 10-year experience by the U.S. Food and Drug Administration
10.1200/jco.2017.35.15_suppl.10009 · 2017 · External reference
Barriers to clinical trial participation by older women with breast cancer
10.1200/jco.2003.09.124 · 2003 · External reference
CDK inhibitors: positive and negative regulators of G1-phase progression
10.1101/gad.13.12.1501 · 1999 · External reference
Co-targeting CDK4/6 and AKT with endocrine therapy prevents progression in CDK4/6 inhibitor and endocrine therapy-resistant breast cancer
2021 · External reference
Abemaciclib plus endocrine therapy for hormone receptor-positive, HER2-negative, node-positive, high-risk early breast cancer (monarchE): results from a preplanned interim analysis of a randomised, open-label, phase 3 trial
10.1016/s1470-2045(22)00694-5 · 2023 · External reference
Ribociclib plus endocrine therapy in early breast Cancer
10.1056/nejmoa2305488 · 2024 · External reference
Adjuvant Palbociclib for early breast cancer: the PALLAS trial results (ABCSG-42/AFT-05/BIG-14-03)
10.1200/jco.21.02554 · 2022 · External reference
Palbociclib for residual high-risk invasive HR-positive and HER2-negative early breast Cancer-the Penelope-B trial
10.1200/jco.20.03639 · 2021 · External reference
Overall survival with abemaciclib in early breast cancer
10.1016/j.annonc.2025.10.005 · 2026 · External reference
Adjuvant ribociclib plus nonsteroidal aromatase inhibitor therapy in patients with HR-positive/HER2-negative early breast cancer: 5-year follow-up of NATALEE efficacy outcomes and updated overall survival
10.1016/j.esmoop.2025.105858 · 2025 · External reference
Toxicity of older and younger patients treated with adjuvant chemotherapy for node-positive breast cancer: the Cancer and Leukemia group B experience
10.1200/jco.2007.10.9710 · 2007 · External reference
Treatment patterns, risk for hospitalization and mortality in older patients with triple negative breast cancer
10.1016/j.jgo.2020.09.004 · 2021 · External reference
Development and validation of a risk tool for predicting severe toxicity in older adults receiving chemotherapy for early-stage breast cancer
10.1200/jco.20.02063 · 2021 · External reference
Breast cancer in older patients: can CDK 4/6 inhibitors make the difference in the adjuvant setting?
10.1016/j.jgo.2025.102213 · 2025 · External reference
Nephrotoxicity in cancer treatment: an update
10.1016/bs.acr.2022.03.005 · 2022 · External reference
Cardiovascular complications of breast cancer therapy in older adults
10.1634/theoncologist.2010-0348 · 2011 · External reference
Bridging the age gap in breast cancer: impact of chemotherapy on quality of life in older women with early breast cancer
10.1016/j.ejca.2020.11.022 · 2021 · External reference
Updated recommendations regarding the management of older patients with breast cancer: a joint paper from the European Society of Breast Cancer Specialists (EUSOMA) and the International Society of Geriatric Oncology (SIOG)
10.1016/s1470-2045(20)30741-5 · 2021 · External reference
Practical assessment and management of vulnerabilities in older patients receiving systemic cancer therapy: ASCO guideline update
10.1200/jco.23.00933 · 2023 · External reference
Screening older cancer patients: first evaluation of the G-8 geriatric screening tool
10.1093/annonc/mdr587 · 2012 · External reference
The Vulnerable Elders Survey: a tool for identifying vulnerable older people in the community
10.1046/j.1532-5415.2001.49281.x · 2001 · External reference
Predicting disease-related and patient-reported outcomes in older patients with breast cancer - a systematic review
10.1016/j.jgo.2021.01.008 · 2021 · External reference
Association between geriatric 8 frailty and health-related quality of life in older patients with cancer (PROGNOSIS-G8): a Danish single-Centre, prospective cohort study
10.1016/s2666-7568(24)00118-1 · 2024 · External reference
A systematic review on the association of the G8 with geriatric assessment, prognosis and course of treatment in older patients with cancer
10.1016/j.jgo.2019.04.016 · 2019 · External reference
Estimating the risk of chemotherapy toxicity in older patients with cancer: the role of the vulnerable elders Survey-13 (VES-13)
10.1016/j.jgo.2015.02.005 · 2015 · External reference
PALOMAGE, a French real-world cohort of elderly women beyond age 70 with advanced breast cancer receiving palbociclib: baseline characteristics and safety evaluation
10.1200/jco.2021.39.15_suppl.1012 · 2021 · External reference
Low-intensity adjuvant chemotherapy for breast cancer in older women: results from the prospective multicenter HOPE trial
10.1200/jco.22.01440 · 2023 · External reference
Overall survival after CDK4/6 inhibitor dose reduction in women with metastatic breast cancer
10.1038/s44276-024-00108-z · 2024 · External reference
Chemotherapy-related toxic effects and quality of life and physical functioning in older patients
10.1001/jamanetworkopen.2023.39116 · 2023 · External reference
Efficacy and safety results by age in monarchE: adjuvant abemaciclib combined with endocrine therapy (ET) in patients with HR+, HER2-, node-positive, high-risk early breast cancer (EBC)
10.1200/jco.2023.41.16_suppl.501 · 2023 · External reference
Impact of dose reductions on adjuvant abemaciclib efficacy for patients with high-risk early breast cancer: analyses from the monarchE study
10.1038/s41523-024-00639-1 · 2024 · External reference
Implementing geriatric assessment for dose optimization of CDK4/6 inhibitors in older breast cancer patients
10.1080/14796694.2024.2413841 · 2024 · External reference
Screening for vulnerability in older cancer patients: the ONCODAGE prospective Multicenter cohort study
10.1371/journal.pone.0115060 · 2014 · External reference
Detecting disabilities in older patients with cancer: comparison between comprehensive geriatric assessment and vulnerable elders survey-13
10.1200/jco.2009.25.9978 · 2010 · External reference