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References from Sex differences in MASLD and fitness improvement during a weight loss intervention for adolescents living with obesity. Local targets link to admitted publications; unresolved targets remain external evidence.
FISPGHAN statement on the global public health impact of metabolic dysfunction‐associated steatotic liver disease
2024 · External reference
Global burden of NAFLD and NASH: trends, predictions, risk factors and prevention
10.1038/nrgastro.2017.109 · 2018 · External reference
A multisociety Delphi consensus statement on new fatty liver disease nomenclature
10.1016/j.aohep.2023.101133 · 2024 · External reference
EASL–EASD–EASO Clinical Practice Guidelines on the management of metabolic dysfunction-associated steatotic liver disease (MASLD)
10.1016/j.jhep.2024.04.031 · 2024 · External reference
Long-term mortality and extrahepatic outcomes in 1096 children with MASLD: A retrospective cohort study
2025 · External reference
Mortality in biopsy-confirmed nonalcoholic fatty liver disease: results from a nationwide cohort
10.1136/gutjnl-2020-322786 · 2021 · External reference
Updates in clinical medicine: MASLD in children and adolescents
10.1016/j.jhep.2026.02.016 · 2026 · External reference
Recent prevalence and trends of obesity and metabolic dysfunction‐associated steatotic liver disease (<scp>MASLD</scp>) among <scp>US</scp> adolescents: 1999 to 2020
10.1111/ijpo.70003 · 2025 · External reference
Epidemiology of metabolic dysfunction-associated steatotic liver disease
10.3350/cmh.2024.0431 · 2025 · External reference
European Society for Pediatric Gastroenterology, Hepatology and Nutrition (ESPGHAN) position paper on screening, diagnosis and investigation of paediatric metabolic dysfunction-associated steatotic liver disease
10.1002/jpn3.70490 · 2026 · External reference
Progression of Fatty Liver Disease in Children Receiving Standard of Care Lifestyle Advice
10.1053/j.gastro.2020.07.034 · 2020 · External reference
Accuracy and reproducibility of transient elastography for the diagnosis of fibrosis in pediatric nonalcoholic steatohepatitis
10.1002/hep.22376 · 2008 · External reference
Transient elastography is a useful noninvasive tool for the evaluation of fibrosis in paediatric chronic liver disease
10.1097/mpg.0b013e31826f2760 · 2013 · External reference
Quick assessment with controlled attenuation parameter for hepatic steatosis in children based on MRI-PDFF as the gold standard
10.1186/s12887-019-1485-8 · 2019 · External reference
Starting Age for Screening Metabolic Dysfunction-Associated Steatotic Liver Disease in Children Using Controlled Attenuation Parameter on Transient Elastography
10.1111/ijpo.70080 · 2026 · External reference
Practical Aspects of Cardiopulmonary Exercise Testing in Children
10.1055/a-2191-0518 · 2024 · External reference
Principles of exercise testing and interpretation
10.1097/00008483-198704000-00014 · 1987 · External reference
Methodological approach to the first and second lactate threshold in incremental cardiopulmonary exercise testing
10.1097/hjr.0b013e328304fed4 · 2008 · External reference
Oxygen-uptake efficiency slope as a determinant of fitness in overweight adolescents
10.1249/mss.0b013e31812e52b3 · 2007 · External reference
Oxygen uptake efficiency slope in children: Its role in exercise testing
10.1177/2047487318810872 · 2019 · External reference
Response profiles of oxygen uptake efficiency during exercise in healthy children
10.1177/2047487315611769 · 2016 · External reference
Assessment of the 5-Minute Oxygen Uptake Efficiency Slope in Children With Obesity
10.1123/pes.2016-0248 · 2017 · External reference
Exercise tolerance in obese vs. lean adolescents: a systematic review and meta‐analysis
10.1111/obr.12202 · 2014 · External reference
Normative values for cardiopulmonary exercise testing in the pediatric population – an updated systematic review
10.1093/eurjpc/zwag168 · 2026 · External reference
Non-Alcoholic Fatty Liver Disease in Children and Adolescents: Lifestyle Change - a Systematic Review and Meta-Analysis
10.5604/01.3001.0011.7380 · 2018 · External reference
Evidence-Based Exercise Recommendations to Reduce Hepatic Fat Content in Youth- a Systematic Review and Meta-Analysis
10.1016/j.pcad.2018.01.013 · 2018 · External reference
Intensive Lifestyle Management Improves Steatosis and Fibrosis in Pediatric Nonalcoholic Fatty Liver Disease
10.1016/j.cgh.2021.11.039 · 2022 · External reference
The effectiveness of multidisciplinary weight loss interventions is associated with initial cardiorespiratory fitness in adolescents with obesity
10.1111/ijpo.13147 · 2024 · External reference
Physical determinants of weight loss during a residential rehabilitation program for adolescents with obesity
2020 · External reference
Homeostasis model assessment: insulin resistance and β-cell function from fasting plasma glucose and insulin concentrations in man
10.1007/bf00280883 · 1985 · External reference
Prevalence of steatosis and fibrosis in young adults in the UK: a population-based study
10.1016/s2468-1253(19)30419-4 · 2020 · External reference
Accuracy of FibroScan Controlled Attenuation Parameter and Liver Stiffness Measurement in Assessing Steatosis and Fibrosis in Patients With Nonalcoholic Fatty Liver Disease
10.1053/j.gastro.2019.01.042 · 2019 · External reference
Comparison of Controlled Attenuation Parameter and Liver Biopsy to Assess Hepatic Steatosis in Pediatric Patients
10.1016/j.jpeds.2016.03.021 · 2016 · External reference
Data Processing Strategies to Determine Maximum Oxygen Uptake: A Systematic Scoping Review and Experimental Comparison with Guidelines for Reporting
10.1007/s40279-023-01903-3 · 2023 · External reference
Prevalence of Metabolically Healthy but Overweight/Obese Phenotype and Its Association With Sedentary Time, Physical Activity, and Fitness
10.1016/j.jadohealth.2017.01.018 · 2017 · External reference
Cardiorespiratory fitness, body mass index and mortality: a systematic review and meta-analysis
10.1136/bjsports-2024-108748 · 2025 · External reference
Is Weight Loss–Induced Muscle Mass Loss Clinically Relevant?
2024 · External reference
Improvement of non-invasive markers of NAFLD from an individualised, web-based exercise program
10.1111/apt.15427 · 2019 · External reference
Sex Differences in Upper- and Lower-Limb Muscle Strength in Children and Adolescents: A Meta-Analysis
10.1002/ejsc.12282 · 2025 · External reference
Sex-related variations in liver homeostasis and disease: From zonation dynamics to clinical implications
10.1016/j.jhep.2025.08.007 · 2026 · External reference
Sex differences in cardiometabolic risk factors and in response to lifestyle intervention in prepubertal and pubertal subjects with obesity
10.3389/fped.2024.1304451 · 2024 · External reference
Percent Body Fat and Weight Status of Youth Participating in Pediatric Weight Management Programs in the Pediatric Obesity Weight Evaluation Registry
10.1089/chi.2023.0201 · 2024 · External reference
Sex as a moderator of body composition following a randomized controlled lifestyle intervention among Latino youth with obesity
2020 · External reference
Sex differences in response to lifestyle intervention among children and adolescents: Systematic review and meta-analysis
10.1002/oby.23663 · 2023 · External reference
Sex Differences in Diet and Physical Activity Behaviors Among Racial/Ethnic Minority Adolescents with High Metabolic Risk
10.1007/s40615-023-01880-3 · 2025 · External reference
Gender Differences in Physiologic Markers and Health Behaviors Associated With Childhood Obesity
10.1542/peds.2012-2994 · 2013 · External reference
Behavioral Weight Loss Intervention Preferences of Adolescents with Overweight/Obesity
10.1089/chi.2020.0296 · 2021 · External reference
Effects of different exercise modalities and intensities on body composition in overweight and obese children and adolescents: a systematic review and network meta-analysis
10.3389/fphys.2023.1193223 · 2023 · External reference
The use of submaximal parameters in the assessment of exercise capacity in children with obesity
10.1111/ijpo.13201 · 2025 · External reference
Influence of grade of obesity on the achievement of VO2max using an incremental treadmill test in youths
10.1080/02640414.2021.1898093 · 2021 · External reference
Chronotropic incompetence is more frequent in obese adolescents and relates to systemic inflammation and exercise intolerance
10.1016/j.jshs.2021.01.010 · 2023 · External reference
Unresolved reference
External reference
Altered gas-exchange at peak exercise in obese adolescents: implications for verification of effort during cardiopulmonary exercise testing
10.23736/s0022-4707.16.06607-x · 2017 · External reference
Comparison of two methods of cardiopulmonary exercise testing for assessing physical fitness in children and adolescents with extreme obesity
10.1007/s00431-022-04434-7 · 2022 · External reference
Reference values and secular trends for cardiorespiratory fitness in children and adolescents with obesity
10.1111/apa.15163 · 2020 · External reference