Research graph
References from Antibiotic versus saline wound irrigation after appendectomy for prevention of incisional surgical site infection: a systematic review and meta-analysis of randomised controlled trials.. Local targets link to admitted publications; unresolved targets remain external evidence.
Acute appendicitis: modern understanding of pathogenesis, diagnosis, and management
10.1016/s0140-6736(15)00275-5 · 2015 · External reference
Global incidence of surgical site infection after appendectomy: a systematic review and meta-analysis
10.1136/bmjopen-2019-034266 · 2020 · External reference
Centers for Disease Control and Prevention Guideline for the Prevention of Surgical Site Infection, 2017
10.1001/jamasurg.2017.0904 · 2017 · External reference
World Health Organization: global guidelines for the prevention of surgical site infection
10.1016/j.jhin.2016.12.016 · 2017 · External reference
Incisional Wound Irrigation for the Prevention of Surgical Site Infection: A Systematic Review and Network Meta-Analysis
10.1001/jamasurg.2024.0775 · 2024 · External reference
Antiseptic wound irrigation to prevent surgical site infection after laparotomy: meta-analysis
10.1093/bjsopen/zraf072 · 2025 · External reference
Diagnosis and treatment of acute appendicitis: 2020 update of the WSES Jerusalem guidelines
10.1186/s13017-020-00306-3 · 2020 · External reference
A randomized controlled trial on irrigation of open appendectomy wound with gentamicin- saline solution versus saline solution for prevention of surgical site infection
10.1016/j.ijsu.2020.07.057 · 2020 · External reference
Role of intraoperative antibiotics wound irrigation in reducing surgical site infection following open appendectomy: a randomized controlled trial
10.1186/s12893-025-03127-w · 2025 · External reference
The PRISMA 2020 statement: an updated guideline for reporting systematic reviews
10.1136/bmj.n71 · 2021 · External reference
AMSTAR 2: a critical appraisal tool for systematic reviews that include randomised or non-randomised studies of healthcare interventions, or both
2017 · External reference
RoB 2: a revised tool for assessing risk of bias in randomised trials
2019 · External reference
GRADE guidelines: 3. Rating the quality of evidence
10.1016/j.jclinepi.2010.07.015 · 2011 · External reference
Meta-analysis in clinical trials revisited
10.1016/j.cct.2015.09.002 · 2015 · External reference
Surgical site infection: Incidence and impact on hospital utilization and treatment costs
10.1016/j.ajic.2008.12.010 · 2009 · External reference
Health and Economic Impact of Surgical Site Infections Diagnosed after Hospital Discharge
10.3201/eid0902.020232 · 2003 · External reference
Surgical Site Infection after Digestive Surgery: Diagnosis and Treatment in a Context of Limited Resources
10.1089/sur.2019.007 · 2020 · External reference
Surgical site infection following abdominal surgery: a prospective cohort study
10.1503/cjs.004818 · 2019 · External reference
Global Surgery 2030: evidence and solutions for achieving health, welfare, and economic development
10.1016/s0140-6736(15)60160-x · 2015 · External reference
Management of acute appendicitis in low- and middle-income countries
10.1016/j.cpsurg.2024.101444 · 2024 · External reference
Challenges to implement laparoscopic appendectomy as the first-line treatment for acute appendicitis: a fifteen-year experience in a tertiary hospital in Brazil
2023 · External reference
Topical Ampicillin for Prophylaxis Against Wound Infection in Acute Appendicitis
10.5144/0256-4947.1994.233 · 1994 · External reference
Prevention of postoperative wound infection after appendectomy by local application of tinidazole: a double‐blind study
10.1007/bf01656415 · 1987 · External reference
10.3329/jninb.v6i1.48031
10.3329/jninb.v6i1.48031 · External reference
Compare the incidence of surgical site infection after appendectomy wound irrigation with normal saline and imipenem solutions
10.53350/pjmhs211582184 · 2021 · External reference
Intra-Operative Wound Irrigation with Normal Saline Solution Versus Topical Antibiotics to Avoid Wound Infection
2024 · External reference
Comparison of Gentamicin Saline Solution and Normal Saline in Reducing Surgical Site Infections in Open Appendectomy: A Randomized Controlled Trial
10.1002/hsr2.71143 · 2025 · External reference
Irrigation of Abdomen With Imipenem Solution Decreases Surgical Site Infections in Patients With Perforated Appendicitis: A Randomized Clinical Trial
10.5812/ircmj.12732 · 2014 · External reference
The Intraperitoneal Use of Cephazolin: A Novelty in the Prevention of Intra-abdominal Abscess after Laparoscopic Appendectomy in Children
10.62713/aic.3381 · 2024 · External reference
The efficacy of metronidazole rinses in reducing surgical site infections and improving wound healing in patients with purulent appendicitis: a systematic review and meta-analysis
10.1186/s12879-025-11994-0 · 2025 · External reference
Trial sequential analysis may establish when firm evidence is reached in cumulative meta-analysis
10.1016/j.jclinepi.2007.03.013 · 2008 · External reference
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