Research graph
References from A Cardioprotective perfusion protocol limits myocardial functional decline during ex situ heart perfusion. Local targets link to admitted publications; unresolved targets remain external evidence.
Ex situ heart perfusion: the past, the present, and the future
10.1016/j.healun.2020.10.004 · 2021 · External reference
Machine perfusion for human heart preservation: a systematic review
10.3389/ti.2022.10258 · 2022 · External reference
Impact of reperfusion calcium and pH on the resuscitation of hearts donated after circulatory death
10.1016/j.athoracsur.2016.05.084 · 2017 · External reference
Dynamic metabolic changes during prolonged ex situ heart perfusion are associated with myocardial functional decline
10.3389/fimmu.2022.859506 · 2022 · External reference
Myocardial functional decline during prolonged ex situ heart perfusion
10.1016/j.athoracsur.2019.01.076 · 2019 · External reference
Oxidative stress and related metabolic alterations are induced in ex situ perfusion of donated hearts regardless of the ventricular load or leukocyte depletion
10.1016/j.ajt.2022.11.027 · 2023 · External reference
Immunity and stress responses are induced during ex situ heart perfusion
10.1161/circheartfailure.119.006552 · 2020 · External reference
Gene therapy during ex situ heart perfusion: a new frontier in cardiac regenerative medicine?
10.3389/fcvm.2023.1264449 · 2023 · External reference
A cardioprotective preservation strategy employing ex vivo heart perfusion facilitates successful transplant of donor hearts after cardiocirculatory death
10.1016/j.healun.2013.04.016 · 2013 · External reference
Cardioprotective reperfusion strategies differentially affect mitochondria: studies in an isolated rat heart model of donation after circulatory death (DCD)
10.1111/ajt.15024 · 2019 · External reference
A whole blood–based perfusate provides superior preservation of myocardial function during ex vivo heart perfusion
10.1016/j.healun.2014.09.021 · 2015 · External reference
Prolonged (24-hour) normothermic ex vivo heart perfusion facilitated by perfusate hemofiltration
10.1097/mat.0000000000001649 · 2022 · External reference
Steroids limit myocardial edema during ex vivo perfusion of hearts donated after circulatory death
10.1016/j.athoracsur.2018.01.004 · 2018 · External reference
The position of the heart during normothermic ex situ heart perfusion is an important factor in preservation and recovery of myocardial function
10.1097/mat.0000000000001386 · 2021 · External reference
Validation of the slaughterhouse porcine heart model for ex-situ heart perfusion studies
2023 · External reference
An ex vivo platform to simulate cardiac physiology: a new dimension for therapy development and assessment
10.5301/ijao.2011.8456 · 2011 · External reference
Investigating the physiology of normothermic ex vivo heart perfusion in an isolated slaughterhouse porcine model used for device testing and training
10.1186/s12872-019-1242-9 · 2019 · External reference
Investigating the physiology of normothermic ex vivo heart perfusion in an isolated slaughterhouse porcine model used for device testing and training
10.1186/s12872-019-1242-9 · 2019 · External reference
Ex vivo lung perfusion: a review of current and future application in lung transplantation
10.1007/s41030-022-00185-w · 2022 · External reference
Prolonged preservation by hypothermic machine perfusion facilitates logistics in liver transplantation: a European observational cohort study
10.1111/ajt.17037 · 2022 · External reference
Normothermic liver machine perfusion as a dynamic platform for regenerative purposes: what does the future have in store for us?
10.1016/j.jhep.2022.04.033 · 2022 · External reference
Ex-vivo kidney machine perfusion: therapeutic potential
2021 · External reference
Myocardial ischemia-reperfusion injury: a neglected therapeutic target
10.1172/jci62874 · 2013 · External reference
Myocardial ischaemia–reperfusion injury and cardioprotection in perspective
10.1038/s41569-020-0403-y · 2020 · External reference
Transplantation of hearts donated after circulatory death
10.3389/fcvm.2018.00008 · 2018 · External reference
Cardioplegia and cardiac surgery: pharmacological arrest and cardioprotection during global ischemia and reperfusion
10.1016/j.pharmthera.2010.04.001 · 2010 · External reference
New directions for protecting the heart against ischaemia–reperfusion injury: targeting the Reperfusion Injury Salvage Kinase (RISK)-pathway
10.1016/j.cardiores.2003.09.024 · 2004 · External reference
Reperfusion injury salvage kinase signalling: taking a RISK for cardioprotection
10.1007/s10741-007-9026-1 · 2007 · External reference
Cardioprotective reperfusion strategies differentially affect mitochondria: studies in an isolated rat heart model of donation after circulatory death (DCD)
10.1111/ajt.15024 · 2019 · External reference
Moderate hypothermia during ex vivo machine perfusion promotes recovery of hearts donated after cardiocirculatory death
10.1093/ejcts/ezv066 · 2016 · External reference
Gradual rewarming with gradual increase in pressure during machine perfusion after cold static preservation reduces kidney ischemia reperfusion injury
10.1371/journal.pone.0143859 · 2015 · External reference
Novel strategy to decrease reperfusion injuries and improve function of cold-preserved livers using normothermic ex vivo liver perfusion machine
10.1002/lt.24352 · 2016 · External reference
Rewarming injury after cold preservation
10.3390/ijms20092059 · 2019 · External reference
Methylprednisolone and tacrolimus prevent hypothermia-induced endothelial dysfunction
10.1016/j.healun.2009.04.003 · 2009 · External reference
Cardiac allograft vasculopathy: current review and future research directions
2021 · External reference
Cardiac allograft vasculopathy after heart transplantation: risk factors and management
10.1016/j.healun.2004.03.009 · 2004 · External reference
Hemofiltration improves blood perfusate conditions leading to improved ex situ heart perfusion
10.1097/mat.0000000000002058 · 2023 · External reference
An integrated perfusion machine preserves injured human livers for 1 week
10.1038/s41587-019-0374-x · 2020 · External reference
Normothermic extracorporeal liver perfusion for donation after cardiac death (DCD) livers
2015 · External reference
Liver transplantation after organ preservation with normothermic extracorporeal perfusion
10.1097/00000658-200101000-00017 · 2001 · External reference
Ex vivo heart perfusion for 72 h using plasma cross circulation
10.1097/mat.0000000000001061 · 2020 · External reference
Twenty-four-hour normothermic perfusion of isolated ex vivo hearts using plasma exchange
10.1016/j.jtcvs.2020.11.158 · 2021 · External reference
Glucose is an ineffective substrate for preservation of machine perfused donor hearts
10.1016/j.jss.2011.05.028 · 2012 · External reference
The proton-linked monocarboxylate transporter (MCT) family: structure, function and regulation
10.1042/bj3430281 · 1999 · External reference
Pyruvate in organ transplantation
10.1177/0148607101025004216 · 2001 · External reference
Antioxidant pyruvate inhibits cardiac formation of reactive oxygen species through changes in redox state
10.1152/ajpheart.2000.279.5.h2431 · 2000 · External reference
Protection by pyrdvate against inhibition of Na+,K+-ATPase by a free radical generating system containing T-butylhydroperoxide
10.1016/0024-3205(95)02028-h · 1995 · External reference
Antioxidant properties of pyruvate mediate its potentiation of β-adrenergic inotropism in stunned myocardium
10.1006/jmcc.1999.1020 · 1999 · External reference
Partitioning of pyruvate between oxidation and anaplerosis in swine hearts
10.1152/ajpheart.2000.279.5.h2390 · 2000 · External reference
