Research graph
References from Erratic tacrolimus levels at 6 to 12 months post-lung transplant predicts poor outcomes. Local targets link to admitted publications; unresolved targets remain external evidence.
Post-transplant obliterative bronchiolitis and other late lung sequelae in human heart-lung transplantation
10.1378/chest.86.6.824 · 1984 · External reference
Health-related quality of life in two hundred-eighty lung transplant recipients
10.1016/j.healun.2005.07.005 · 2005 · External reference
Chronic lung allograft dysfunction: Definition, diagnostic criteria, and approaches to treatment-a consensus report from the Pulmonary Council of the ISHLT
10.1016/j.healun.2019.03.009 · 2019 · External reference
A randomized controlled trial of tacrolimus versus cyclosporine after lung transplantation
10.1016/j.healun.2007.07.027 · 2007 · External reference
Clinical trial of tacrolimus versus cyclosporine in lung transplantation
10.1016/0003-4975(95)00407-c · 1995 · External reference
Tacrolimus versus cyclosporin as primary immunosuppression for lung transplant recipients
10.1002/14651858.cd008817.pub2 · 2013 · External reference
Tacrolimus and cyclosporine have differential effects on the risk of development of bronchiolitis obliterans syndrome: results of a prospective, randomized international trial in lung transplantation
10.1016/j.healun.2012.03.008 · 2012 · External reference
Tacrolimus versus cyclosporine after lung transplantation: a prospective, open, randomized two-center trial comparing two different immunosuppressive protocols
10.1016/s1053-2498(01)00244-3 · 2001 · External reference
The Registry of the International Society for Heart and Lung Transplantation: Thirtieth Adult Lung and Heart-Lung Transplant Report--2013; focus theme: age
10.1016/j.healun.2013.08.007 · 2013 · External reference
Effect of once-per-day tacrolimus versus twice-per-day ciclosporin on 3-year incidence of chronic lung allograft dysfunction after lung transplantation in Scandinavia (ScanCLAD): a multicentre randomised controlled trial
2023 · External reference
The International Thoracic Organ Transplant Registry of the International Society for Heart and Lung Transplantation: Thirty-fifth adult lung and heart-lung transplant report-2018; Focus theme: Multiorgan Transplantation
10.1016/j.healun.2018.07.020 · 2018 · External reference
The International Thoracic Organ Transplant Registry of the International Society for Heart and Lung Transplantation: thirty-eighth adult lung transplantation report - 2021; focus on recipient characteristics
10.1016/j.healun.2021.07.021 · 2021 · External reference
High within-patient variability in the clearance of tacrolimus is a risk factor for poor long-term outcome after kidney transplantation
10.1093/ndt/gfq096 · 2010 · External reference
Non-adherence and graft failure in adult liver transplant recipients
10.1007/s10620-012-2412-0 · 2013 · External reference
Variability in tacrolimus blood levels increases the risk of late rejection and graft loss after solid organ transplantation in older children
10.1111/j.1399-3046.2010.01409.x · 2010 · External reference
Erratic tacrolimus exposure, assessed using the standard deviation of trough blood levels, predicts chronic lung allograft dysfunction and survival
10.1016/j.healun.2015.05.028 · 2015 · External reference
10.21203/rs.2.10537/v1
10.21203/rs.2.10537/v1 · External reference
Analytical performance characteristics of the Abbott Architect i2000 Tacrolimus assay; comparisons with liquid chromatography-tandem mass spectrometry (LC-MS/MS) and Abbott IMx methods
10.1016/j.cca.2009.09.009 · 2009 · External reference
Coefficient of variation
1998 · External reference
Tacrolimus intrapatient variability in solid organ transplantation: a multiorgan perspective
10.1002/phar.2480 · 2021 · External reference
Within-patient variability in tacrolimus blood levels predicts kidney graft loss and donor-specific antibody development
10.1097/tp.0000000000001040 · 2016 · External reference
A high intrapatient variability in tacrolimus exposure is associated with poor long-term outcome of kidney transplantation
10.1111/tri.12798 · 2016 · External reference
High intrapatient tacrolimus variability is associated with worse outcomes in renal transplantation using a low-dose tacrolimus immunosuppressive regime
10.1097/tp.0000000000001129 · 2017 · External reference
High intrapatient variability of tacrolimus levels and outpatient clinic nonattendance are associated with inferior outcomes in renal transplant patients
2017 · External reference
High intrapatient variability of tacrolimus concentrations predicts accelerated progression of chronic histologic lesions in renal recipients
10.1111/ajt.13803 · 2016 · External reference
High intrapatient variability in tacrolimus exposure is not associated with immune-mediated graft injury after liver transplantation
10.1097/tp.0000000000002680 · 2019 · External reference
Medication level variability index predicts rejection, possibly due to nonadherence, in adult liver transplant recipients
10.1002/lt.23930 · 2014 · External reference
High intrapatient variability of tacrolimus exposure in the early period after liver transplantation is associated with poorer outcomes
10.1097/tp.0000000000002052 · 2018 · External reference
High tacrolimus intra-patient variability is associated with graft rejection, and de novo donor-specific antibodies occurrence after liver transplantation
10.3748/wjg.v24.i16.1795 · 2018 · External reference
High tacrolimus trough level variability is associated with rejections after heart transplant
10.1111/ajt.15016 · 2018 · External reference
Increasing tacrolimus time-in-therapeutic range is associated with superior one-year outcomes in lung transplant recipients
10.1111/ajt.14723 · 2018 · External reference
Antifungal activities of tacrolimus in combination with antifungal agents against fluconazole-susceptible and fluconazole-resistant Trichosporon asahii isolates
10.1016/j.bjid.2016.08.008 · 2016 · External reference
Unresolved reference
External reference
Patient compliance in transplantation: a report on the perceptions of transplant clinicians
10.1016/s0041-1345(99)00113-x · 1999 · External reference
Adherence of heart transplant recipients to prescribed medication and recommended lifestyle habits
10.1177/1526924817699959 · 2017 · External reference
Prospective randomized trial investigating the influence of pharmaceutical care on the intra-individual variability of tacrolimus concentrations early after kidney transplant
2016 · External reference
A pilot randomized controlled trial to promote immunosuppressant adherence in adult kidney transplant recipients
10.1159/000448627 · 2017 · External reference
Transplant surgery enters a new era: Increasing immunosuppressive medication adherence through mobile apps and smart watches
10.1016/j.amjsurg.2019.02.018 · 2019 · External reference
Exploratory analysis of the impact of an mhealth medication adherence intervention on tacrolimus trough concentration variability: post hoc results of a randomized controlled trial
10.1177/1060028020931806 · 2020 · External reference
Lower variability in 24-hour exposure during once-daily compared to twice-daily tacrolimus formulation in kidney transplantation
10.1097/01.tp.0000437561.31212.0e · 2014 · External reference
Lower variability of tacrolimus trough concentration after conversion from prograf to advagraf in stable kidney transplant recipients
10.1097/tp.0b013e3182292426 · 2011 · External reference
Tacrolimus level variability is a novel measure associated with increased acute rejection in lung transplant (LTx) recipients
10.1016/j.healun.2013.01.404 · 2013 · External reference
Effect of CYP3A5*3 on kidney transplant recipients treated with tacrolimus: a systematic review and meta-analysis of observational studies
10.1038/tpj.2014.38 · 2015 · External reference
Impact of the CYP3A5, CYP3A4, COMT, IL-10 and POR genetic polymorphisms on tacrolimus metabolism in Chinese renal transplant recipients
2014 · External reference