Research graph
References from Engineering and preclinical development of hydrogels for dermatologic drug delivery. Local targets link to admitted publications; unresolved targets remain external evidence.
Photostability and interaction of ascorbic acid in cream formulations
10.1208/s12249-011-9659-1 · 2011 · External reference
A bio-instructive, bioactive in situ polymerizable wound matrix promotes scar-free burn wound repair
10.1016/j.isci.2025.112471 · 2025 · External reference
Research techniques made simple: transepidermal water loss measurement as a research tool
10.1016/j.jid.2018.09.001 · 2018 · External reference
Evaluation of the clinical impact of repeat application of hydrogel-forming microneedle array patches
10.1007/s13346-020-00727-2 · 2020 · External reference
Anti-wrinkle efficacy of cross-linked hyaluronic acid-based microneedle patch with acetyl Hexapeptide-8 and epidermal growth factor on Korean skin
10.5021/ad.2019.31.3.263 · 2019 · External reference
Application of dermal microdialysis for the determination of bioavailability of clobetasol propionate applied to the skin of human subjects
10.1159/000330489 · 2012 · External reference
Injectable preformed scaffolds with shape-memory properties
10.1073/pnas.1211516109 · 2012 · External reference
A novel dual action monolithic thermosetting hydrogel loaded with lidocaine and metronidazole as a potential treatment for alveolar osteitis
10.1016/j.ejpb.2020.01.007 · 2020 · External reference
Bioequivalence of topical formulations in humans: evaluation by dermal microdialysis sampling and the dermatopharmacokinetic method
10.1038/sj.jid.5700495 · 2007 · External reference
Preclinical study of methotrexate-based hydrogels versus surfactant based liquid crystal systems on psoriasis treatment
10.1016/j.ejps.2021.105956 · 2021 · External reference
Clinical investigation of use of an antimicrobial peptide hydrogel wound dressing on intact skin
10.12968/jowc.2023.32.6.368 · 2023 · External reference
Open flow microperfusion as a dermal pharmacokinetic approach to evaluate topical bioequivalence [published correction appears in Clin Pharmacokinet 2017;56:99]
10.1007/s40262-016-0442-z · 2017 · External reference
MALDI imaging facilitates new topical drug development process by determining quantitative skin distribution profiles
10.1007/s00216-018-0964-3 · 2018 · External reference
Efficacy and safety of topical nitric oxide-releasing berdazimer gel in patients with molluscum contagiosum: a Phase 3 randomized clinical trial
2022 · External reference
Hydrogel crosslinking modulates macrophages, fibroblasts, and their communication, during wound healing
10.1038/s41467-024-50072-y · 2024 · External reference
Joint profiling of chromatin accessibility and gene expression in thousands of single cells
10.1126/science.aau0730 · 2018 · External reference
Pharmacokinetic profile, safety, and tolerability of topical berdazimer gel, 10.3% in patients with molluscum contagiosum
10.36849/jdd.6938 · 2022 · External reference
In vivo confocal Raman microspectroscopy of the skin: noninvasive determination of molecular concentration profiles
10.1046/j.1523-1747.2001.01258.x · 2001 · External reference
Transdermal vaccination via 3D-printed microneedles induces potent humoral and cellular immunity
10.1073/pnas.2102595118 · 2021 · External reference
bFGF and collagen matrix hydrogel attenuates burn wound inflammation through activation of ERK and TRK pathway
10.1038/s41598-021-82888-9 · 2021 · External reference
Bacteria-responsive hydrogel for on-demand release of antimicrobial peptides that prevent superbug infections and promote wound healing
10.1016/j.colcom.2023.100752 · 2023 · External reference
Methods to assess shear-thinning hydrogels for application as injectable biomaterials
10.1021/acsbiomaterials.7b00734 · 2017 · External reference
Dry-coated microprojection array patches for targeted delivery of immunotherapeutics to the skin
10.1016/j.jconrel.2009.06.029 · 2009 · External reference
Nanoparticle targeting to scalp hair follicles: new perspectives for a topical therapy for alopecia areata
10.1016/j.jid.2019.05.028 · 2020 · External reference
Transdermal delivery of desmopressin using a coated microneedle array patch system
10.1016/s0168-3659(04)00171-3 · 2004 · External reference
Microneedle-mediated transdermal delivery of bevacizumab
10.1021/acs.molpharmaceut.8b00544 · 2018 · External reference
Stem cell-containing hyaluronic acid-based spongy hydrogels for integrated diabetic wound healing
10.1016/j.jid.2017.02.976 · 2017 · External reference
High-throughput sequencing of the T cell receptor β gene identifies aggressive early-stage mycosis fungoides
10.1126/scitranslmed.aar5894 · 2018 · External reference
Composite dissolving microneedles for coordinated control of antigen and adjuvant delivery kinetics in transcutaneous vaccination
10.1002/adfm.201201512 · 2013 · External reference
Spatial profiling of chromatin accessibility in mouse and human tissues
10.1038/s41586-022-05094-1 · 2022 · External reference
Transdermal delivery of siRNA through microneedle array
2016 · External reference
Topical delivery of Anti-TNFα siRNA and capsaicin via novel lipid-polymer hybrid nanoparticles efficiently inhibits skin inflammation in vivo
10.1016/j.jconrel.2013.04.021 · 2013 · External reference
Hydrogel-forming microneedle arrays for enhanced transdermal drug delivery
10.1002/adfm.201200864 · 2012 · External reference
Enhanced skin deposition of betamethasone dipropionate from a novel formulation and drug delivery technology
10.1007/s13555-023-00959-3 · 2023 · External reference
Secukinumab distributes into dermal interstitial fluid of psoriasis patients as demonstrated by open flow microperfusion
10.1111/exd.12863 · 2016 · External reference
Assessing the risk of a clinically significant infection from a Microneedle Array Patch (MAP) product
10.1016/j.jconrel.2023.07.001 · 2023 · External reference
White paper: understanding, informing and defining the regulatory science of microneedle-based dosage forms that are applied to the skin
10.1016/j.jconrel.2024.11.056 · 2025 · External reference
In situ forming injectable thermoresponsive hydrogels for controlled delivery of biomacromolecules
10.1021/acsomega.0c02009 · 2020 · External reference
In-vivo dynamic characterization of microneedle skin penetration using optical coherence tomography
10.1117/1.3463002 · 2010 · External reference
Crosslinking hyaluronic acid soft-tissue fillers: current status and perspectives from an industrial point of view
10.1080/17434440.2021.2014320 · 2021 · External reference
Analyzing immune response to engineered hydrogels by hierarchical clustering of inflammatory cell subsets
10.1126/sciadv.abd8056 · 2022 · External reference
A framework for multi-Omic prediction of treatment response to biologic therapy for psoriasis
10.1016/j.jid.2018.04.041 · 2019 · External reference
Single-cell analysis of psoriasis resolution demonstrates an inflammatory fibroblast state targeted by IL-23 blockade
10.1038/s41467-024-44994-w · 2024 · External reference
Biocompatibility and characterization of polyglycerol-based thermoresponsive nanogels designed as novel drug-delivery systems and their intracellular localization in keratinocytes
10.1080/17435390.2017.1292371 · 2017 · External reference
Correlation between the chemical composition of thermoresponsive nanogels and their interaction with the skin barrier
10.1016/j.jconrel.2016.10.022 · 2016 · External reference
Breaking the barrier - potent anti-inflammatory activity following efficient topical delivery of etanercept using thermoresponsive nanogels
10.7150/thno.21668 · 2018 · External reference
Laser-engineered dissolving microneedles for active transdermal delivery of nadroparin calcium
10.1016/j.ejpb.2012.07.008 · 2012 · External reference
Multiplexed spatial mapping of chromatin features, transcriptome and proteins in tissues
10.1038/s41592-024-02576-0 · 2025 · External reference
Lipid nanoparticles efficiently deliver the base editor ABE8e for COL7A1 correction in dystrophic epidermolysis bullosa fibroblasts in vitro
10.1016/j.jid.2024.03.027 · 2024 · External reference
Skin basal cell carcinomas assemble a pro-tumorigenic spatially organized and self-propagating Trem2+ myeloid niche
10.1038/s41467-023-37993-w · 2023 · External reference
Hydrogel increases diclofenac skin permeation and absorption
10.1002/bdd.2194 · 2019 · External reference
Characterizing cutaneous drug delivery using open-flow microperfusion and mass spectrometry imaging
10.1021/acs.molpharmaceut.1c00285 · 2021 · External reference
Hydrogel-forming microneedle arrays made from light-responsive materials for on-demand transdermal drug delivery
10.1021/acs.molpharmaceut.5b00807 · 2016 · External reference
Effect of steam sterilization and biocompatibility studies of hyaluronic acid hydrogel for viscosupplementation
10.1016/j.polymdegradstab.2019.03.019 · 2019 · External reference
Tape strips detect distinct immune and barrier profiles in atopic dermatitis and psoriasis
10.1016/j.jaci.2020.05.048 · 2021 · External reference
Tape-strip proteomic profiling of atopic dermatitis on Dupilumab identifies minimally invasive biomarkers
10.3389/fimmu.2020.01768 · 2020 · External reference
Microneedle-delivered adeno-associated virus vaccine amplified anti-viral immunity by improving antigen-presenting cells infection
10.1016/j.jconrel.2025.01.069 · 2025 · External reference
Effects of gamma irradiation and supercritical carbon dioxide sterilization on methacrylated gelatin/hyaluronan hydrogels
10.3390/jfb14060317 · 2023 · External reference
Fractional laser-assisted topical delivery of bleomycin quantified by LC-MS and visualized by MALDI mass spectrometry imaging
10.1080/10717544.2019.1574937 · 2019 · External reference
Microfabricated microneedles: a novel approach to transdermal drug delivery [published correction appears in J Pharm Sci 1998;88:948]
10.1021/js980042+ · 1998 · External reference
Methods for the determination of the substantivity of topical formulations
10.3109/10837450.2015.1135346 · 2017 · External reference
Measurement of the penetration of 56 cosmetic relevant chemicals into and through human skin using a standardized protocol
10.1002/jat.3913 · 2020 · External reference
Protease-modulating polyacrylate-based hydrogel stimulates wound bed preparation in venous leg ulcers--a randomized controlled trial
10.1111/jdv.12400 · 2014 · External reference
Dissolving microneedle with high molecular weight hyaluronic acid to improve skin wrinkles, dermal density and elasticity
10.1111/ics.12617 · 2020 · External reference
Spatial transcriptomics for profiling the tropism of viral vectors in tissues
10.1038/s41587-022-01648-w · 2023 · External reference
Intradermal indocyanine green for in vivo fluorescence laser scanning microscopy of human skin: a pilot study
10.1371/journal.pone.0023972 · 2011 · External reference
Comparative physical properties of hyaluronic acid dermal fillers
10.1111/j.1524-4725.2008.01046.x · 2009 · External reference
In situ-formable, dynamic crosslinked poly(ethylene glycol) carrier for localized adeno-associated virus infection and reduced off-target effects
10.1038/s42003-023-04851-w · 2023 · External reference
Comparison of microdialysis sampling perfusion fluid components on the foreign body reaction in rat subcutaneous tissue
10.1016/j.ejps.2013.11.005 · 2014 · External reference
Systemic bioavailability of topical diclofenac sodium gel 1% versus oral diclofenac sodium in healthy volunteers
10.1177/0091270009336234 · 2010 · External reference
Microneedle Array Patch (MAP) consisting of crosslinked hyaluronic acid nanoparticles for processability and sustained release
10.1007/s11095-020-2768-3 · 2020 · External reference
BCG hydrogel promotes CTSS-mediated antigen processing and presentation, thereby suppressing metastasis and prolonging survival in melanoma
10.1136/jitc-2021-004133 · 2022 · External reference
Photocrosslinked gelatin hydrogel improves wound healing and skin flap survival by the sustained release of basic fibroblast growth factor
10.1038/s41598-021-02589-1 · 2021 · External reference
Assessing the integrity and mechanical properties of commercial microneedles: innovation or fad?
10.1007/s13346-025-01888-8 · 2025 · External reference
Hyaluronic acid detection and relative quantification by mass spectrometry imaging in human skin tissues
10.1007/s00216-022-04139-8 · 2022 · External reference
Direct analysis and MALDI imaging of formalin-fixed, paraffin-embedded tissue sections
10.1021/pr060549i · 2007 · External reference
Highly multiplexed immunofluorescence imaging of human tissues and tumors using t-CyCIF and conventional optical microscopes
10.7554/elife.31657 · 2018 · External reference
Shear-thinning and self-healing hydrogels as injectable therapeutics and for 3D-printing
10.1038/nprot.2017.053 · 2017 · External reference
Glycosaminoglycan-based hydrogels capture inflammatory chemokines and rescue defective wound healing in mice
10.1126/scitranslmed.aai9044 · 2017 · External reference
Spatially resolved epigenomic profiling of single cells in complex tissues [published correction appears in Cell 2023;186:2275–9]
10.1016/j.cell.2022.09.035 · 2022 · External reference
High-mass-resolution MALDI mass spectrometry imaging of metabolites from formalin-fixed paraffin-embedded tissue
10.1038/nprot.2016.081 · 2016 · External reference
Temporal progression of the host response to implanted poly(ethylene glycol)-based hydrogels
10.1002/jbm.a.33015 · 2011 · External reference
Single cell and spatial sequencing define processes by which keratinocytes and fibroblasts amplify inflammatory responses in psoriasis
10.1038/s41467-023-39020-4 · 2023 · External reference
Microinfusion using hollow microneedles
10.1007/s11095-005-8498-8 · 2006 · External reference
From the laboratory to the end-user: a primary packaging study for microneedle patches containing amoxicillin sodium
10.1007/s13346-020-00883-5 · 2021 · External reference
Generation of an inflammatory niche in a hydrogel depot through recruitment of key immune cells improves efficacy of mRNA vaccines
10.1126/sciadv.adr2631 · 2025 · External reference
Spatially mapping the immune landscape of melanoma using imaging mass cytometry
10.1126/sciimmunol.abi5072 · 2022 · External reference
Visualizing the neutrophil response to sterile tissue injury in mouse dermis reveals a three-phase cascade of events
10.1038/jid.2011.179 · 2011 · External reference
Toxicity and photosensitizing assessment of gelatin methacryloyl-based hydrogels photoinitiated with lithium phenyl-2,4,6-trimethylbenzoylphosphinate in human primary renal proximal tubule epithelial cells
10.1116/1.5095886 · 2019 · External reference
Dermatopharmacokinetics: factors influencing drug clearance from the stratum corneum
10.1007/s11095-008-9785-y · 2009 · External reference
Design and characterization of matrix metalloproteinase-responsive hydrogels for the treatment of inflammatory skin diseases
10.1016/j.actbio.2022.12.015 · 2023 · External reference
Evaluation of skin penetration of fluorescent dissolved formulations using confocal laser scanning microscopy
10.3390/pharmaceutics17121534 · 2025 · External reference
Bioluminescent murine models of bacterial sepsis and scald wound infections for antimicrobial efficacy testing
10.1371/journal.pone.0200195 · 2018 · External reference
In vivo stratum corneum distribution of lidocaine, assessed by tape stripping, from a new bioadhesive film
10.1111/j.1600-0846.2009.00407.x · 2010 · External reference
Preparation and characterization of breathable hemostatic hydrogel dressings and determination of their effects on full-thickness defects
10.3390/polym9120727 · 2017 · External reference
Intradermal delivery of STAT3 siRNA to treat melanoma via dissolving microneedles
10.1038/s41598-018-19463-2 · 2018 · External reference
Diffusion of macromolecules in extracellular matrix mimetic hydrogels - effect of size and charge
10.1016/j.ejps.2025.107257 · 2025 · External reference
Spatial mass cytometry-based single-cell imaging reveals a disrupted epithelial-immune axis in prurigo Nodularis
10.1016/j.jid.2024.01.036 · 2024 · External reference
Stratum corneum sampling to assess bioequivalence between topical acyclovir products
10.1007/s11095-019-2707-3 · 2019 · External reference
Nanoparticle-driven self-assembling injectable hydrogels provide a multi-factorial approach for chronic wound treatment
10.1016/j.actbio.2021.07.020 · 2021 · External reference
Highly multiplexed phenotyping of immunoregulatory proteins in the tumor microenvironment by CODEX tissue imaging
10.3389/fimmu.2021.687673 · 2021 · External reference
Heparin-regulated release of growth factors in vitro and angiogenic response in vivo to implanted hyaluronan hydrogels containing VEGF and bFGF
10.1016/j.biomaterials.2006.05.018 · 2006 · External reference
Nanofibrous supramolecular peptide hydrogels for controlled release of small-molecule drugs and biologics
10.1038/s41565-025-01981-6 · 2025 · External reference
ROS-responsive hydrogels with spatiotemporally sequential delivery of antibacterial and anti-inflammatory drugs for the repair of MRSA-infected wounds
10.1093/rb/rbad110 · 2024 · External reference
Biodegradable core-multishell nanocarrier: topical tacrolimus delivery for treatment of dermatitis
10.1016/j.jconrel.2022.07.025 · 2022 · External reference
Effect of sterilization treatment on mechanical properties, biodegradation, bioactivity and printability of GelMA hydrogels
10.1088/1748-605x/aba40c · 2020 · External reference
Alginate microbeads are complement compatible, in contrast to polycation containing microcapsules, as revealed in a human whole blood model
10.1016/j.actbio.2011.03.011 · 2011 · External reference
The safety, immunogenicity, and acceptability of inactivated influenza vaccine delivered by microneedle patch (TIV-MNP 2015): a randomised, partly blinded, placebo-controlled, phase 1 trial
10.1016/s0140-6736(17)30575-5 · 2017 · External reference
Circulating immune landscape profiling in psoriasis vulgaris and psoriatic arthritis by mass cytometry
10.1155/2024/9927964 · 2024 · External reference
Finite dose skin mass balance including the lateral part: comparison between experiment, pharmacokinetic modeling and diffusion models
10.1016/j.jconrel.2012.10.009 · 2013 · External reference
Hyaluronic acid-based hybrid hydrogel microspheres with enhanced structural stability and high injectability
10.1021/acsomega.9b01475 · 2019 · External reference
Skin permeating nanogel for the cutaneous co-delivery of two anti-inflammatory drugs
10.1016/j.biomaterials.2011.11.011 · 2012 · External reference
Optimization of an adeno-associated viral vector for epidermal keratinocytes in vitro and in vivo
10.1016/j.jdermsci.2024.07.006 · 2024 · External reference
Cutaneous microdialysis: cytokine evidence for altered innate reactivity in the skin of psoriasis patients?
10.1208/s12248-012-9331-z · 2012 · External reference
Imaging the distribution of skin lipids and topically applied compounds in human skin using mass spectrometry
10.1038/s41598-018-34286-x · 2018 · External reference
In-situ formed elastin-based hydrogels enhance wound healing via promoting innate immune cells recruitment and angiogenesis
2022 · External reference
Cutaneous pharmacokinetics-based bioequivalence: a clinical dermal open flow microperfusion verification study using lidocaine and prilocaine combination topical products
10.1016/j.ejps.2024.106827 · 2024 · External reference
Noninvasive tape-stripping with high-resolution RNA profiling effectively captures a Preinflammatory State in nonlesional psoriatic skin
10.1016/j.jid.2021.09.038 · 2022 · External reference
Imaging of injectable hydrogels delivered into myocardium with SPECT/CT
10.1002/adhm.202000294 · 2020 · External reference
Microneedle-based drug and vaccine delivery via nanoporous microneedle arrays
10.1007/s13346-015-0238-y · 2015 · External reference
Impact-insertion applicator improves reliability of skin penetration by solid microneedle arrays
10.1208/s12248-014-9606-7 · 2014 · External reference
The use of a pressure-indicating sensor film to provide feedback upon hydrogel-forming microneedle array self-application in vivo
10.1007/s11095-016-2032-z · 2016 · External reference
Engineering bioactive self-healing antibacterial exosomes hydrogel for promoting chronic diabetic wound healing and complete skin regeneration
10.7150/thno.29766 · 2019 · External reference
ROS/pH dual-responsive hydrogel dressings loaded with amphiphilic structured nano micelles for the repair of infected wounds
10.2147/ijn.s522589 · 2025 · External reference
Injectable and protease-degradable hydrogel for siRNA sequestration and triggered delivery to the heart
10.1016/j.jconrel.2018.07.004 · 2018 · External reference
Local and sustained miRNA delivery from an injectable hydrogel promotes cardiomyocyte proliferation and functional regeneration after ischemic injury
10.1038/s41551-017-0157-y · 2017 · External reference
Injectable, guest-host assembled polyethylenimine hydrogel for siRNA delivery
10.1021/acs.biomac.6b01378 · 2017 · External reference
Controlled release of minoxidil through hydrogel cross-linking to treat androgenetic alopecia
10.1021/acsbiomaterials.5c00292 · 2025 · External reference
Local and sustained baricitinib delivery to the skin through injectable hydrogels containing reversible thioimidate adducts
2024 · External reference
Accelerating diabetic wound healing by ROS-scavenging lipid nanoparticle-mRNA formulation
2024 · External reference
Stage-responsive multifunctional microneedle patches for enhanced biofilm penetration and accelerated healing of bacterial infected skin wounds
10.1021/acsami.5c20107 · 2025 · External reference
First-line interactive wound dressing update: a comprehensive review of the evidence
10.3389/fphar.2020.00155 · 2020 · External reference
Comparative study of physicochemical properties of alginate composite hydrogels prepared by the physical blending and electrostatic assembly methods
10.3390/gels8120799 · 2022 · External reference
Use of RT-PCR and DNA microarrays to characterize RNA recovered by non-invasive tape harvesting of normal and inflamed skin
10.1111/j.0022-202x.2004.22729.x · 2004 · External reference
Bacteria-responsive programmed self-activating antibacterial hydrogel to remodel regeneration microenvironment for infected wound healing
10.1093/nsr/nwae044 · 2024 · External reference
Effect of cross-linking reagents for hyaluronic acid hydrogel dermal fillers on tissue augmentation and regeneration
10.1021/bc9002647 · 2010 · External reference
Injectable self-healing glucose-responsive hydrogels with pH-regulated mechanical properties
10.1002/adma.201502902 · 2016 · External reference
Persistence of skin-resident memory T cells within an epidermal niche
10.1073/pnas.1322292111 · 2014 · External reference
Efficient loading and sustained delivery of methotrexate using a tip-swellable microneedle array patch for psoriasis treatment
10.1021/acsbiomaterials.3c01810 · 2024 · External reference
Autoreactive B cell differentiation in diffuse ectopic lymphoid-like structures of inflamed pemphigus lesions
10.1016/j.jid.2019.07.717 · 2020 · External reference
Non-invasive transdermal delivery of biomacromolecules with fluorocarbon-modified chitosan for melanoma immunotherapy and viral vaccines
10.1038/s41467-024-45158-6 · 2024 · External reference
Solute diffusion and interactions in cross-linked poly(ethylene glycol) hydrogels studied by Fluorescence correlation spectroscopy
10.1039/c0sm00111b · 2010 · External reference
Characterization of protein release from hydrolytically degradable poly(ethylene glycol) hydrogels
10.1002/bit.22911 · 2011 · External reference
