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References from TLR4 epidermal genetic deletion protects against acute and tumorigenic UV exposure in SKH-1 mouse skin.. Local targets link to admitted publications; unresolved targets remain external evidence.
Solar Simulated Light Induces Cutaneous Squamous Cell Carcinoma in Inbred Mice: A Clinically Relevant Model to Investigate T-Cell Responses
10.1016/j.jid.2021.06.005 · 2021 · External reference
Toll-like receptor-4 deficiency inhibits ultraviolet radiation-induced tumor development by modulation of immune and inflammatory responses
10.1002/mc.23271 · 2021 · External reference
Pharmacological Agents Used in the Prevention and Treatment of Actinic Keratosis: A Review
10.3390/ijms24054989 · 2023 · External reference
Pharmacological TLR4 Antagonism Using Topical Resatorvid Blocks Solar UV-Induced Skin Tumorigenesis in SKH-1 Mice
10.1158/1940-6207.capr-17-0349 · 2018 · External reference
Toll-like receptors and skin cancer
10.3389/fimmu.2014.00135 · 2014 · External reference
Role of gut-derived bacterial lipopolysaccharide and peripheral TLR4 in immobilization stress-induced itch aggravation in a mouse model of atopic dermatitis
10.1038/s41598-024-56936-z · 2024 · External reference
Increased PD-L1 Expression in Human Skin Acutely and Chronically Exposed to UV Irradiation
10.1111/php.13406 · 2021 · External reference
Inhibition of UV-Induced Stress Signaling and Inflammatory Responses in SKH-1 Mouse Skin by Topical Small-Molecule PD-L1 Blockade
10.1016/j.xjidi.2023.100255 · 2024 · External reference
TLR4 in skin cancer: From molecular mechanisms to clinical interventions
10.1002/mc.23016 · 2019 · External reference
Protein signaling and drug target activation signatures to guide therapy prioritization: Therapeutic resistance and sensitivity in the I-SPY 2 Trial
2023 · External reference
Imiquimod 5% cream for the treatment of superficial basal cell carcinoma: a double-blind, randomized, vehicle-controlled study
10.1067/mjd.2002.126215 · 2002 · External reference
Resatorvid-based Pharmacological Antagonism of Cutaneous TLR4 Blocks UV-induced NF-kappaB and AP-1 Signaling in Keratinocytes and Mouse Skin
10.1111/php.12659 · 2016 · External reference
Genetic Target Modulation Employing CRISPR/Cas9 Identifies Glyoxalase 1 as a Novel Molecular Determinant of Invasion and Metastasis in A375 Human Malignant Melanoma Cells In Vitro and In Vivo
10.3390/cancers12061369 · 2020 · External reference
Topical hypochlorous acid (HOCl) blocks inflammatory gene expression and tumorigenic progression in UV-exposed SKH-1 high risk mouse skin
10.1016/j.redox.2021.102042 · 2021 · External reference
Targeted deletion and lipidomic analysis identify epithelial cell COX-2 as a major driver of chemically induced skin cancer
10.1158/1541-7786.mcr-14-0397-t · 2014 · External reference
Cell-type-specific roles for COX-2 in UVB-induced skin cancer
10.1093/carcin/bgu020 · 2014 · External reference
Epidermal p65/NF-kappaB signalling is essential for skin carcinogenesis
10.15252/emmm.201303541 · 2014 · External reference
Toll-like receptor 4 (TLR4): new insight immune and aging
10.1186/s12979-023-00383-3 · 2023 · External reference
The chemopreventive efficacies of nonsteroidal anti-inflammatory drugs: the relationship of short-term biomarkers to long-term skin tumor outcome
10.1158/1940-6207.capr-13-0064 · 2013 · External reference
TLR4-mediated skin carcinogenesis is dependent on immune and radioresistant cells
10.1038/emboj.2010.94 · 2010 · External reference
Chemokine expression by human keratinocyte cell lines after activation of Toll-like receptors
10.1111/j.1600-0625.2009.01026.x · 2010 · External reference
Preparation and use of reverse protein microarrays
2014 · External reference
NIH Image to ImageJ: 25 years of image analysis
10.1038/nmeth.2089 · 2012 · External reference
Toll-Like Receptor-4 Antagonist Enhances the Repair of Ultraviolet Radiation-Induced DNA Damage and Augments Anti-Tumor Immune Responses in Mice
10.3390/cancers13215406 · 2021 · External reference
IFN-alpha enhances peptide vaccine-induced CD8+ T cell numbers, effector function, and antitumor activity
10.4049/jimmunol.0802982 · 2009 · External reference
The Central Roles of Keratinocytes in Coordinating Skin Immunity
10.1016/j.jid.2024.06.1280 · 2024 · External reference
Recent Advances in Clinical Research for Skin Cancer Chemoprevention
10.3390/cancers15153819 · 2023 · External reference
