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References from Clinico-genomic risk stratification for biomarker-enriched trial design in poor-prognosis metastatic castrate-resistant prostate cancer (mCRPC). Local targets link to admitted publications; unresolved targets remain external evidence.
Cancer treatment and survivorship statistics, 2025
2025 · External reference
A bayesian network meta-analysis of systemic treatments for metastatic castration-resistant prostate cancer in First- and subsequent lines
10.1007/s11523-025-01148-2 · 2025 · External reference
Abiraterone acetate plus prednisone versus placebo plus prednisone in chemotherapy-naive men with metastatic castration-resistant prostate cancer (COU-AA-302): final overall survival analysis of a randomised, double-blind, placebo-controlled phase 3 study
10.1016/s1470-2045(14)71205-7 · 2015 · External reference
Enzalutamide in men with chemotherapy-naive metastatic castration-resistant prostate cancer: extended analysis of the phase 3 PREVAIL study
10.1016/j.eururo.2016.07.032 · 2017 · External reference
Cabazitaxel versus abiraterone or enzalutamide for poor-prognosis metastatic castration-resistant prostate cancer after docetaxel: a phase 2 trial with a circulating tumor DNA analysis
2025 · External reference
External validation of a prognostic model of overall survival in men with chemotherapy-naive metastatic castration-resistant prostate cancer
10.1200/jco.22.02661 · 2023 · External reference
Overall survival of black and white men with metastatic castration-resistant prostate cancer treated with docetaxel
10.1200/jco.18.01279 · 2019 · External reference
Prognostic model predicting metastatic castration-resistant prostate cancer survival in men treated with second-line chemotherapy
10.1093/jnci/djt280 · 2013 · External reference
Updated prognostic model for predicting overall survival in first-line chemotherapy for patients with metastatic castration-resistant prostate cancer
10.1200/jco.2013.52.3696 · 2014 · External reference
Prognostic index model for progression-free survival in chemotherapy-naive metastatic castration-resistant prostate cancer treated with abiraterone acetate plus prednisone
2017 · External reference
Clinical and genomic insights into circulating tumor DNA-based alterations across the spectrum of metastatic hormone-sensitive and castrate-resistant prostate cancer
10.1016/j.ebiom.2020.102728 · 2020 · External reference
Plasma cell–free DNA profiling of PTEN-PI3K-AKT pathway aberrations in metastatic castration-resistant prostate cancer
10.1200/po.20.00424 · 2021 · External reference
Exosomal miR-1290 and miR-375 as prognostic markers in castration-resistant prostate cancer
10.1016/j.eururo.2014.07.035 · 2015 · External reference
Prognostic association of plasma cell-free DNA-based androgen receptor amplification and circulating tumor cells in pre-chemotherapy metastatic castration-resistant prostate cancer patients
10.1038/s41391-018-0043-z · 2018 · External reference
Plasma copy number alteration-based prognostic and predictive multi-gene risk score in metastatic castration-resistant prostate cancer
10.3390/cancers14194714 · 2022 · External reference
Plasma AR and abiraterone-resistant prostate cancer
10.1126/scitranslmed.aac9511 · 2015 · External reference
Multi-gene risk score for prediction of clinical outcomes in treatment-naive metastatic castrate-resistant prostate cancer
10.1093/jncics/pkaf025 · 2025 · External reference
Pathogenic genomic alterations in circulating tumor DNA predict overall survival in men with metastatic castrate-resistant prostate cancer
2025 · External reference
Liquid biopsy testing in urological cancers: focus on urine
10.1016/j.urolonc.2025.07.034 · 2025 · External reference
Blood and urine-based biomarkers in prostate cancer: current advances, clinical applications, and future directions
10.1016/j.jlb.2025.100305 · 2025 · External reference
Molecular subtypes of diffuse large B cell lymphoma are associated with distinct pathogenic mechanisms and outcomes
10.1038/s41591-018-0016-8 · 2018 · External reference
Validation of a prognostic model and the impact of mutations in patients with lower-risk myelodysplastic syndromes
10.1200/jco.2011.40.7379 · 2012 · External reference
Prognostic and predictive biomarker developments in multiple myeloma
10.1186/s13045-021-01162-7 · 2021 · External reference
IPSS-M risk and specific sex-associated somatic mutations predict response to ESA therapy in LR-MDS: building a new score
10.1182/blood.2024027540 · 2025 · External reference
Unresolved reference
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Unresolved reference
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Survival with olaparib in metastatic castration-resistant prostate cancer
10.1056/nejmoa2022485 · 2020 · External reference
DNA-repair defects and olaparib in metastatic prostate cancer
10.1056/nejmoa1506859 · 2015 · External reference
PARP inhibitor-based treatment in metastatic, castration-resistant prostate cancer (mCRPC): a systematic review and meta-analysis
10.1002/bco2.455 · 2025 · External reference
Clinico-genomic nomograms for estimation of survival risk in metastatic castrate-resistant prostate cancer
10.1093/jncics/pkag042 · 2026 · External reference
Clinical and genomic risk to guide the use of adjuvant therapy for breast cancer
10.1056/nejmoa1904819 · 2019 · External reference
Adjuvant chemotherapy guided by a 21-Gene expression assay in breast cancer
10.1056/nejmoa1804710 · 2018 · External reference
Multigene copy number alteration risk score biomarker-based enrichment study designs in metastatic castrate-resistant prostate cancer
2024 · External reference
A prospective genome-wide study of prostate cancer metastases reveals association of wnt pathway activation and increased cell cycle proliferation with primary resistance to abiraterone acetate-prednisone
10.1093/annonc/mdx689 · 2018 · External reference
Molecular profile changes in patients with castrate-resistant prostate cancer Pre- and post-Abiraterone/Prednisone treatment
10.1158/1541-7786.mcr-22-0099 · 2022 · External reference
Prediction of plasma ctDNA fraction and prognostic implications of liquid biopsy in advanced prostate cancer
10.1038/s41467-024-45475-w · 2024 · External reference
Nonparametric estimation of lifetime and disease onset distributions from incomplete observations
10.2307/2529872 · 1982 · External reference
Evaluating the yield of medical tests
10.1001/jama.1982.03320430047030 · 1982 · External reference
Pharmacogenetics- and pharmacogenomics-based rational clinical trial designs in oncology
2013 · External reference
Integrative clinical genomics of advanced prostate cancer
10.1016/j.cell.2015.05.001 · 2015 · External reference
First-line camizestrant for emerging ESR1-Mutated advanced breast cancer
10.1056/nejmoa2502929 · 2025 · External reference
Olaparib for metastatic castration-resistant prostate cancer
10.1056/nejmoa1911440 · 2020 · External reference
Rucaparib or physician's choice in metastatic prostate cancer
10.1056/nejmoa2214676 · 2023 · External reference
Niraparib plus abiraterone acetate with prednisone in patients with metastatic castration-resistant prostate cancer and homologous recombination repair gene alterations: second interim analysis of the randomized phase III MAGNITUDE trial
10.1016/j.annonc.2023.06.009 · 2023 · External reference
Pembrolizumab in microsatellite instability high or mismatch repair deficient cancers: updated analysis from the phase II KEYNOTE-158 study
10.1016/j.annonc.2022.05.519 · 2022 · External reference
Prospective multicenter validation of androgen receptor splice variant 7 and hormone therapy resistance in high-risk castration-resistant prostate cancer: the PROPHECY study
10.1200/jco.18.01731 · 2019 · External reference
Final overall survival and molecular data associated with clinical outcomes in patients receiving ipatasertib and abiraterone in the phase 3 IPATential150 trial
10.1016/j.eururo.2024.12.015 · 2025 · External reference
Value of the 21-gene expression assay in predicting locoregional recurrence rates in estrogen receptor-positive breast cancer: a systematic review and network meta-analysis
10.1007/s10549-022-06580-w · 2022 · External reference
Combined Tumor suppressor defects characterize clinically defined aggressive variant prostate cancers
10.1158/1078-0432.ccr-15-1259 · 2016 · External reference